Zhigang He

31.0k citations

116 papers · 21.8k indexed · 16 hit papers · h-index 69

Cellular and Molecular Neuroscience top 0.02%
Molecular Biology top 0.5%
Developmental Neuroscience top 0.01%
Pathology and Forensic Medicine top 0.2%
Cell Biology top 0.2%

Co-authors: Marc Tessier‐Lavigne Glenn Yiu Kevin K. ParkKe WangRajeev SivasankaranKai LiuChen WangHang Chen
Topics: Nerve injury and regeneration (63 papers)Neurogenesis and neuroplasticity mechanisms (51 papers)Axon Guidance and Neuronal Signaling (42 papers)
Cited by: Developmental Neuroscience Cellular and Molecular Neuroscience Neurology
Journals: Nature Science Cell
Partner nations: United States China Canada

In The Last Decade

Zhigang He

116 papers receiving 21.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

2008 1.3k citations Kai Liu, Zhigang He et al. Science profile →
Glial inhibition of CNS axon regeneration

2006 1.2k citations Glenn Yiu, Zhigang He Nature reviews. Neuroscience profile →
Neuropilin Is a Receptor for the Axonal Chemorepellent Semaphorin III

1997 972 citations Zhigang He, Marc Tessier‐Lavigne Cell profile →
Plexins Are a Large Family of Receptors for Transmembrane, Secreted, and GPI-Anchored Semaphorins in Vertebrates

1999 950 citations Hang Chen, Zhigang He et al. Cell profile →
Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth

2002 749 citations Ke Wang, Zhigang He et al. profile →
PTEN deletion enhances the regenerative ability of adult corticospinal neurons

2010 746 citations Kai Liu, Yi Lu et al. Nature Neuroscience profile →
Conversion of Neuronal Growth Cone Responses from Repulsion to Attraction by Cyclic Nucleotides

1998 679 citations Guo‐li Ming, Zhigang He et al. Science profile →
p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp

2002 649 citations Ke Wang, Zhigang He et al. profile →
Neuropilin-2, a Novel Member of the Neuropilin Family, Is a High Affinity Receptor for the Semaphorins Sema E and Sema IV but Not Sema III

1997 563 citations Hang Chen, Zhigang He et al. Neuron profile →
Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

2011 558 citations Guoping Feng, Zhigang He et al. profile →
PTPσ Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

2009 536 citations Yingjie Shen, Alan P. Tenney et al. Science profile →
Intrinsic Control of Axon Regeneration

2016 427 citations Zhigang He, Yishi Jin Neuron profile →
Required growth facilitators propel axon regeneration across complete spinal cord injury

2018 386 citations Yan Ao, Alexander M. Bernstein et al. profile →
Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes

2019 380 citations Wenjun Yan, Zhigang He et al. Neuron profile →
Microglia-organized scar-free spinal cord repair in neonatal mice

2020 288 citations Riki Kawaguchi, Aboozar Monavarfeshani et al. profile →
Microglia coordinate cellular interactions during spinal cord repair in mice

2022 176 citations Faith H. Brennan, Yang Li et al. Nature Communications profile →

Peers

Countries citing papers authored by Zhigang He

Since Specialization

Citations

This map shows the geographic impact of Zhigang He's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhigang He with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhigang He more than expected).

Fields of papers citing papers by Zhigang He

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhigang He. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhigang He. The network helps show where Zhigang He may publish in the future.

Co-authorship network of co-authors of Zhigang He

This figure shows the co-authorship network connecting the top 25 collaborators of Zhigang He. A scholar is included among the top collaborators of Zhigang He based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhigang He. Zhigang He is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Traumatic spinal cord injury: a review of the current state of art and future directions – what do we know and where are we going? 2025 ·North American Spine Society Journal (NASSJ) ·(unknown),Joshua I. Chalif,Benjamin R. Johnston,Eric Chalif,(unknown),Saef Izzy,Zhigang He,Rajiv Saigal,Michael G. Fehlings,Yi Lu	4
2	Anisotropic hydrogel microelectrodes for intraspinal neural recordings in vivo 2025 ·Nature Communications ·Sizhe Huang,(unknown),Shaoting Lin,Z. Y. Wu,(unknown),(unknown),(unknown),(unknown),Fake Lu,(unknown),Xinyue Liu,Atharva Sahasrabudhe,Zicong Zhang,Zhigang He,Alfred J. Crosby,(unknown),Tingyi Liu,Qianbin Wang,Siyuan Rao	7
3	LINC00662 promotes melanoma progression by competitively binding miR-107 and activating the β-catenin signaling pathway 2023 ·International Journal of Medical Sciences ·Mengmeng Luo,(unknown),(unknown),(unknown),Zhigang He,(unknown)	5
4	Fatigue-resistant hydrogel optical fibers enable peripheral nerve optogenetics during locomotion 2023 ·Nature Methods ·Xinyue Liu,Siyuan Rao,Weixuan Chen,(unknown),Jiahua Ni,Atharva Sahasrabudhe,Shaoting Lin,Qianbin Wang,Yuanyuan Liu,Zhigang He,Jingyi Xu,Sizhe Huang,Eunji Hong,(unknown),Polina Anikeeva,Xuanhe Zhao	61
5	Transcriptomic analysis of the ocular posterior segment completes a cell atlas of the human eye 2023 ·Proceedings of the National Academy of Sciences ·Aboozar Monavarfeshani,Wenjun Yan,(unknown),(unknown),Zhigang He,Ayellet V. Segrè,Tavé van Zyl,Gregory S. Hageman,Joshua R. Sanes	18
6	Microglia coordinate cellular interactions during spinal cord repair in micebreakdown → 2022 ·Nature Communications ·Faith H. Brennan,Yang Li,Cankun Wang,Anjun Ma,Qi Guo,(unknown),(unknown),Warren A. Campbell,Kristina G. Witcher,Zhen Guan,Kristina A. Kigerl,Jodie C.E. Hall,Jonathan P. Godbout,Andy J. Fischer,Dana M. McTigue,Zhigang He,Qin Ma,Phillip G. Popovich	176
7	Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice 2022 ·Nature Communications ·Yuyan Cheng,Yuqin Yin,Alice Zhang,Alexander M. Bernstein,Riki Kawaguchi,Kun Gao,(unknown),Hui-ya Gilbert,Yan Ao,Jing Ou,(unknown),Jeffrey L. Goldberg,Zhigang He,Clifford J. Woolf,Michael V. Sofroniew,Larry I. Benowitz,Daniel H. Geschwind	35
8	Reciprocal repulsions instruct the precise assembly of parallel hippocampal networks 2021 ·Science ·Daniel T. Pederick,Jan H. Lui,(unknown),Chuanyun Xu,Mark J. Wagner,Yuanyuan Liu,Zhigang He,Stephen R. Quake,Liqun Luo	42
9	MyelTracer: A Semi-Automated Software for Myeling-Ratio Quantification 2021 ·eNeuro ·Tobias Kaiser,(unknown),(unknown),Boaz Barak,Jing Wang,Zhigang He,Minqing Jiang,Guoping Feng	55
10	Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug 2019 ·Nature Neuroscience ·Boaz Barak,Zicong Zhang,Yuanyuan Liu,(unknown),(unknown),(unknown),Kirsten Levandowski,Dongqing Wang,Kathleen B. Quast,Gabriella L. Boulting,Yi Li,Dashzeveg Bayarsaihan,Zhigang He,Guoping Feng	86
11	Intrinsic Control of Axon Regenerationbreakdown → 2016 ·Neuron ·Zhigang He,Yishi Jin	427
12	Subtype-Specific Regeneration of Retinal Ganglion Cells following Axotomy: Effects of Osteopontin and mTOR Signaling 2015 ·Neuron ·Xin Duan,Mu Qiao,Fengfeng Bei,In-Jung Kim,Zhigang He,Joshua R. Sanes	375
13	WldS, Nmnats and axon degeneration-progress in the past two decades 2010 ·Protein & Cell ·Yan Feng,Tiebin Yan,Zhigang He,Qiwei Zhai	20
14	PTPσ Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regenerationbreakdown → 2009 ·Science ·Yingjie Shen,Alan P. Tenney,Sarah A. Busch,Kevin P. Horn,Fernando X. Cuascut,Kai Liu,Zhigang He,Jerry Silver,John G. Flanagan	536
15	beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones 2008 ·Molecular Brain ·Eyleen L. K. Goh,(unknown),Ken-ichiro Kuwako,Marc Tessier‐Lavigne,Zhigang He,John W. Griffin,Guo‐li Ming	63
16	Assessment of functional recovery and axonal sprouting in oligodendrocyte-myelin glycoprotein (OMgp) null mice after spinal cord injury 2008 ·Molecular and Cellular Neuroscience ·Benxiu Ji,Lauren C. Case,Kai Liu,Zhaohui Shao,Xinhua Lee,Zhongshu Yang,Joy Wang,(unknown),Svetlana Shulga‐Morskaya,Martin Scott,Zhigang He,Jane K. Relton,Sha Mi	48
17	Glial inhibition of CNS axon regenerationbreakdown → 2006 ·Nature reviews. Neuroscience ·Glenn Yiu,Zhigang He	1189
18	Structure of the Nogo Receptor Ectodomain 2003 ·Neuron ·Xiaolin He,J. Fernando Bazán,Gerry McDermott,Jong Bae Park,Ke Wang,Marc Tessier‐Lavigne,Zhigang He,K. Christopher García	166
19	Semaphorin–Neuropilin Interactions Underlying Sympathetic Axon Responses to Class III Semaphorins 1998 ·Neuron ·Hang Chen,Zhigang He,Anil Bagri,Marc Tessier‐Lavigne	249
20	The transactivator proteins VP16 and GAL4 bind replication factor A 1993 ·Cell ·Zhigang He,Bradford T. Brinton,Jack Greenblatt,John A. Hassell,C. James Ingles	196

About Zhigang He

Zhigang He is a scholar working on Developmental Neuroscience, Cellular and Molecular Neuroscience and Neurology, having authored 116 papers that have together received 21.8k indexed citations. Recurring topics across this work include Nerve injury and regeneration (63 papers), Neurogenesis and neuroplasticity mechanisms (51 papers) and Axon Guidance and Neuronal Signaling (42 papers). The work is most often cited by research in Developmental Neuroscience (7.8k citations), Cellular and Molecular Neuroscience (14.7k citations) and Neurology (2.0k citations). Zhigang He has collaborated with scholars based in United States, China and Canada. Frequent co-authors include Marc Tessier‐Lavigne, Glenn Yiu, Kevin K. Park, Ke Wang, Rajeev Sivasankaran, Kai Liu, Chen Wang, Hang Chen, Vuk Koprivica and Guo‐li Ming. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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