Zhigang He

31.0k total citations · 16 hit papers
116 papers, 21.8k citations indexed

About

Zhigang He is a scholar working on Cellular and Molecular Neuroscience, Developmental Neuroscience and Molecular Biology. According to data from OpenAlex, Zhigang He has authored 116 papers receiving a total of 21.8k indexed citations (citations by other indexed papers that have themselves been cited), including 81 papers in Cellular and Molecular Neuroscience, 53 papers in Developmental Neuroscience and 43 papers in Molecular Biology. Recurrent topics in Zhigang He's work include Nerve injury and regeneration (63 papers), Neurogenesis and neuroplasticity mechanisms (51 papers) and Axon Guidance and Neuronal Signaling (42 papers). Zhigang He is often cited by papers focused on Nerve injury and regeneration (63 papers), Neurogenesis and neuroplasticity mechanisms (51 papers) and Axon Guidance and Neuronal Signaling (42 papers). Zhigang He collaborates with scholars based in United States, China and Canada. Zhigang He's co-authors include Marc Tessier‐Lavigne, Glenn Yiu, Kevin K. Park, Ke Wang, Rajeev Sivasankaran, Kai Liu, Chen Wang, Hang Chen, Vuk Koprivica and Guo‐li Ming and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Zhigang He

116 papers receiving 21.6k citations

Hit Papers

Promoting Axon Regeneration in the Adult CNS by Modul... 1997 2026 2006 2016 2008 2006 1997 1999 2002 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway
    2008 1.3k citations Kai Liu, Zhigang He et al. Science profile →
  2. Glial inhibition of CNS axon regeneration
    2006 1.2k citations Glenn Yiu, Zhigang He Nature reviews. Neuroscience profile →
  3. Neuropilin Is a Receptor for the Axonal Chemorepellent Semaphorin III
    1997 972 citations Zhigang He, Marc Tessier‐Lavigne Cell profile →
  4. Plexins Are a Large Family of Receptors for Transmembrane, Secreted, and GPI-Anchored Semaphorins in Vertebrates
    1999 950 citations Hang Chen, Zhigang He et al. Cell profile →
  5. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth
    2002 749 citations Ke Wang, Zhigang He et al. profile →
  6. PTEN deletion enhances the regenerative ability of adult corticospinal neurons
    2010 746 citations Kai Liu, Yi Lu et al. Nature Neuroscience profile →
  7. Conversion of Neuronal Growth Cone Responses from Repulsion to Attraction by Cyclic Nucleotides
    1998 679 citations Guo‐li Ming, Zhigang He et al. Science profile →
  8. p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp
    2002 649 citations Ke Wang, Zhigang He et al. profile →
  9. Neuropilin-2, a Novel Member of the Neuropilin Family, Is a High Affinity Receptor for the Semaphorins Sema E and Sema IV but Not Sema III
    1997 563 citations Hang Chen, Zhigang He et al. Neuron profile →
  10. Sustained axon regeneration induced by co-deletion of PTEN and SOCS3
    2011 558 citations Guoping Feng, Zhigang He et al. profile →
  11. PTPσ Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration
    2009 536 citations Yingjie Shen, Alan P. Tenney et al. Science profile →
  12. Intrinsic Control of Axon Regeneration
    2016 427 citations Zhigang He, Yishi Jin Neuron profile →
  13. Required growth facilitators propel axon regeneration across complete spinal cord injury
    2018 386 citations Yan Ao, Alexander M. Bernstein et al. profile →
  14. Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes
    2019 380 citations Wenjun Yan, Zhigang He et al. Neuron profile →
  15. Microglia-organized scar-free spinal cord repair in neonatal mice
    2020 288 citations Riki Kawaguchi, Aboozar Monavarfeshani et al. profile →
  16. Microglia coordinate cellular interactions during spinal cord repair in mice
    2022 176 citations Faith H. Brennan, Yang Li et al. Nature Communications profile →

Peers

Zhigang He
Jerry Silver United States
Charles ffrench‐Constant United Kingdom
Yves‐Alain Barde Germany
Michael Sendtner Germany
Ueli Suter Switzerland
Barbara L. Hempstead United States
Joost Verhaagen Netherlands
Ronald W. Oppenheim United States
Freda D. Miller Canada
William D. Snider United States
Jerry Silver United States
Zhigang He
Citations per year, relative to Zhigang He Zhigang He (= 1×) peers Jerry Silver

Countries citing papers authored by Zhigang He

Since Specialization
Citations

This map shows the geographic impact of Zhigang He's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhigang He with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhigang He more than expected).

Fields of papers citing papers by Zhigang He

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhigang He. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhigang He. The network helps show where Zhigang He may publish in the future.

Co-authorship network of co-authors of Zhigang He

This figure shows the co-authorship network connecting the top 25 collaborators of Zhigang He. A scholar is included among the top collaborators of Zhigang He based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhigang He. Zhigang He is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chalif, Joshua I., Benjamin R. Johnston, Eric Chalif, et al.. (2025). Traumatic spinal cord injury: a review of the current state of art and future directions – what do we know and where are we going?. North American Spine Society Journal (NASSJ). 22. 100601–100601. 4 indexed citations
2.
Huang, Sizhe, Shaoting Lin, Z. Y. Wu, et al.. (2025). Anisotropic hydrogel microelectrodes for intraspinal neural recordings in vivo. Nature Communications. 16(1). 1127–1127. 7 indexed citations
3.
Luo, Mengmeng, et al.. (2023). LINC00662 promotes melanoma progression by competitively binding miR-107 and activating the β-catenin signaling pathway. International Journal of Medical Sciences. 21(2). 265–276. 5 indexed citations
4.
Liu, Xinyue, Siyuan Rao, Weixuan Chen, et al.. (2023). Fatigue-resistant hydrogel optical fibers enable peripheral nerve optogenetics during locomotion. Nature Methods. 20(11). 1802–1809. 61 indexed citations
5.
Monavarfeshani, Aboozar, Wenjun Yan, Zhigang He, et al.. (2023). Transcriptomic analysis of the ocular posterior segment completes a cell atlas of the human eye. Proceedings of the National Academy of Sciences. 120(34). e2306153120–e2306153120. 18 indexed citations
6.
Brennan, Faith H., Yang Li, Cankun Wang, et al.. (2022). Microglia coordinate cellular interactions during spinal cord repair in mice. Nature Communications. 13(1). 4096–4096. 176 indexed citations breakdown →
7.
Cheng, Yuyan, Yuqin Yin, Alice Zhang, et al.. (2022). Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice. Nature Communications. 13(1). 4418–4418. 35 indexed citations
8.
Pederick, Daniel T., Jan H. Lui, Chuanyun Xu, et al.. (2021). Reciprocal repulsions instruct the precise assembly of parallel hippocampal networks. Science. 372(6546). 1068–1073. 42 indexed citations
9.
Kaiser, Tobias, Boaz Barak, Jing Wang, et al.. (2021). MyelTracer: A Semi-Automated Software for Myeling-Ratio Quantification. eNeuro. 8(4). ENEURO.0558–20.2021. 55 indexed citations
10.
Barak, Boaz, Zicong Zhang, Yuanyuan Liu, et al.. (2019). Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug. Nature Neuroscience. 22(5). 700–708. 86 indexed citations
11.
He, Zhigang & Yishi Jin. (2016). Intrinsic Control of Axon Regeneration. Neuron. 90(3). 437–451. 427 indexed citations breakdown →
12.
Duan, Xin, Mu Qiao, Fengfeng Bei, et al.. (2015). Subtype-Specific Regeneration of Retinal Ganglion Cells following Axotomy: Effects of Osteopontin and mTOR Signaling. Neuron. 85(6). 1244–1256. 375 indexed citations
13.
Feng, Yan, Tiebin Yan, Zhigang He, & Qiwei Zhai. (2010). WldS, Nmnats and axon degeneration-progress in the past two decades. Protein & Cell. 1(3). 237–245. 20 indexed citations
14.
Shen, Yingjie, Alan P. Tenney, Sarah A. Busch, et al.. (2009). PTPσ Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration. Science. 326(5952). 592–596. 536 indexed citations breakdown →
15.
Goh, Eyleen L. K., Ken-ichiro Kuwako, Marc Tessier‐Lavigne, et al.. (2008). beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones. Molecular Brain. 1(1). 10–10. 63 indexed citations
16.
Ji, Benxiu, Lauren C. Case, Kai Liu, et al.. (2008). Assessment of functional recovery and axonal sprouting in oligodendrocyte-myelin glycoprotein (OMgp) null mice after spinal cord injury. Molecular and Cellular Neuroscience. 39(2). 258–267. 48 indexed citations
17.
Yiu, Glenn & Zhigang He. (2006). Glial inhibition of CNS axon regeneration. Nature reviews. Neuroscience. 7(8). 617–627. 1189 indexed citations breakdown →
18.
He, Xiaolin, J. Fernando Bazán, Gerry McDermott, et al.. (2003). Structure of the Nogo Receptor Ectodomain. Neuron. 38(2). 177–185. 166 indexed citations
19.
Chen, Hang, Zhigang He, Anil Bagri, & Marc Tessier‐Lavigne. (1998). Semaphorin–Neuropilin Interactions Underlying Sympathetic Axon Responses to Class III Semaphorins. Neuron. 21(6). 1283–1290. 249 indexed citations
20.
He, Zhigang, Bradford T. Brinton, Jack Greenblatt, John A. Hassell, & C. James Ingles. (1993). The transactivator proteins VP16 and GAL4 bind replication factor A. Cell. 73(6). 1223–1232. 196 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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