Zhen Guan

3.7k total citations · 2 hit papers
67 papers, 2.9k citations indexed

About

Zhen Guan is a scholar working on Pathology and Forensic Medicine, Cellular and Molecular Neuroscience and Oncology. According to data from OpenAlex, Zhen Guan has authored 67 papers receiving a total of 2.9k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Pathology and Forensic Medicine, 14 papers in Cellular and Molecular Neuroscience and 14 papers in Oncology. Recurrent topics in Zhen Guan's work include Spinal Cord Injury Research (18 papers), Colorectal Cancer Surgical Treatments (13 papers) and Neuroinflammation and Neurodegeneration Mechanisms (9 papers). Zhen Guan is often cited by papers focused on Spinal Cord Injury Research (18 papers), Colorectal Cancer Surgical Treatments (13 papers) and Neuroinflammation and Neurodegeneration Mechanisms (9 papers). Zhen Guan collaborates with scholars based in United States, China and Ethiopia. Zhen Guan's co-authors include Phillip G. Popovich, Bradford T. Stokes, Ping Wei, Nico van Rooijen, Daniel P. Ankeny, Inge Huitinga, Lyn B. Jakeman, Lesley C. Fisher, D. Michele Basso and Dana M. McTigue and has published in prestigious journals such as Journal of Clinical Investigation, Nature Communications and Journal of Neuroscience.

In The Last Decade

Zhen Guan

66 papers receiving 2.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Depletion of Hematogenous Macrophages Promotes Partial Hindlimb Recovery and Neuroanatomical Repair after Experimental Spinal Cord Injury

1999 566 citations Phillip G. Popovich, Zhen Guan et al. Experimental Neurology profile →
Microglia coordinate cellular interactions during spinal cord repair in mice

2022 176 citations Faith H. Brennan, Yang Li et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Zhen Guan United States	25	1.5k	983	824	589	529	67	2.9k
Daniel P. Ankeny United States	16	1.4k 0.9×	987 1.0×	1.2k 1.5×	622 1.1×	739 1.4×	17	3.2k
Antje Kroner Germany	29	1.3k 0.9×	775 0.8×	1.2k 1.4×	983 1.7×	1.1k 2.1×	55	3.8k
Ehud Hauben Israel	29	788 0.5×	714 0.7×	1.0k 1.3×	912 1.5×	1.2k 2.3×	51	3.7k
Lesley C. Fisher United States	13	1.6k 1.1×	824 0.8×	476 0.6×	390 0.7×	160 0.3×	22	2.3k
Ravid Shechter Israel	17	769 0.5×	967 1.0×	1.7k 2.0×	740 1.3×	1.1k 2.0×	21	3.6k
Marc J. Ruitenberg Australia	40	888 0.6×	1.8k 1.8×	1.2k 1.5×	1.2k 2.1×	874 1.7×	83	4.7k
Alex E. Marcillo United States	20	1.8k 1.2×	964 1.0×	377 0.5×	599 1.0×	177 0.3×	25	2.8k
Jason R. Plemel Canada	30	1.9k 1.3×	1.5k 1.6×	1.1k 1.3×	1.1k 1.9×	438 0.8×	54	4.2k
David P. Stirling United States	18	792 0.5×	671 0.7×	638 0.8×	413 0.7×	216 0.4×	28	1.8k
Sven Hendrix Belgium	30	539 0.4×	613 0.6×	500 0.6×	567 1.0×	596 1.1×	71	2.4k

Countries citing papers authored by Zhen Guan

Since Specialization

Citations

This map shows the geographic impact of Zhen Guan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhen Guan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhen Guan more than expected).

Fields of papers citing papers by Zhen Guan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhen Guan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhen Guan. The network helps show where Zhen Guan may publish in the future.

Co-authorship network of co-authors of Zhen Guan

This figure shows the co-authorship network connecting the top 25 collaborators of Zhen Guan. A scholar is included among the top collaborators of Zhen Guan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhen Guan. Zhen Guan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Li, Qingyang, et al.. (2025). A method of matching nodes between MRI and pathology with MRI-based 3D node map in rectal cancer. Abdominal Radiology. 50(9). 4004–4014.

Guan, Zhen, et al.. (2025). Predicting Regional Lymph Node Metastases at CT in Microsatellite Instability–High Colon Cancer. Radiology. 315(1). e242122–e242122. 1 indexed citations

Shi, Yan‐Jie, Xin Yang, Zhen Guan, et al.. (2024). Early Contrast-Enhanced MR for Diagnosing Complete Tumor Response of Locally Advanced Esophageal Squamous Cell Carcinoma After Neoadjuvant Therapy: A Retrospective Comparative Study. Annals of Surgical Oncology. 31(7). 4271–4280. 2 indexed citations

Guan, Zhen, Xianwei Zhang, Shuangmei Zou, et al.. (2024). Evaluation of tumor budding with virtual panCK stains generated by novel multi-model CNN framework. Computer Methods and Programs in Biomedicine. 257. 108352–108352. 1 indexed citations

Qi, Jun, Zhen Guan, Chang Zhang, et al.. (2024). Fiber-Optic Distributed Acoustic Sensing for Smart Grid Application. Photonics. 12(1). 7–7. 2 indexed citations

Li, Qingyang, Haitao Zhu, Xiaoyan Zhang, et al.. (2024). Fully semantic segmentation for rectal cancer based on post-nCRT MRl modality and deep learning framework. BMC Cancer. 24(1). 315–315. 2 indexed citations

Brennan, Faith H., Yang Li, Cankun Wang, et al.. (2022). Microglia coordinate cellular interactions during spinal cord repair in mice. Nature Communications. 13(1). 4096–4096. 176 indexed citations breakdown →

Gottipati, Manoj K., Devan L. Puhl, Zhen Guan, et al.. (2021). Acute Dose-Dependent Neuroprotective Effects of Poly(pro-17β-estradiol) in a Mouse Model of Spinal Contusion Injury. ACS Chemical Neuroscience. 12(6). 959–965. 4 indexed citations

Freria, Camila Marques, Faith H. Brennan, David R. Sweet, et al.. (2020). Serial Systemic Injections of Endotoxin (LPS) Elicit Neuroprotective Spinal Cord Microglia through IL-1-Dependent Cross Talk with Endothelial Cells. Journal of Neuroscience. 40(47). 9103–9120. 24 indexed citations

10.

Freria, Camila Marques, Jodie C.E. Hall, Ping Wei, et al.. (2017). Deletion of the Fractalkine Receptor, CX3CR1, Improves Endogenous Repair, Axon Sprouting, and Synaptogenesis after Spinal Cord Injury in Mice. Journal of Neuroscience. 37(13). 3568–3587. 72 indexed citations

11.

Gensel, John C., Yan Wang, Zhen Guan, et al.. (2015). Toll-Like Receptors and Dectin-1, a C-Type Lectin Receptor, Trigger Divergent Functions in CNS Macrophages. Journal of Neuroscience. 35(27). 9966–9976. 56 indexed citations

12.

Kigerl, Kristina A., Daniel P. Ankeny, Sanjay K. Garg, et al.. (2011). System xc− regulates microglia and macrophage glutamate excitotoxicity in vivo. Experimental Neurology. 233(1). 333–341. 55 indexed citations

13.

Gensel, John C., et al.. (2009). Macrophages Promote Axon Regeneration with Concurrent Neurotoxicity. Journal of Neuroscience. 29(12). 3956–3968. 186 indexed citations

14.

Song, Fei, Ingrid E. Gienapp, Todd Shawler, Zhen Guan, & Caroline C. Whitacre. (2004). The Thymus Plays a Role in Oral Tolerance Induction in Experimental Autoimmune Encephalomyelitis. Annals of the New York Academy of Sciences. 1029(1). 402–404. 2 indexed citations

15.

Jakeman, Lyn B., Zhen Guan, Ping Wei, et al.. (2000). Traumatic Spinal Cord Injury Produced by Controlled Contusion in Mouse. Journal of Neurotrauma. 17(4). 299–319. 172 indexed citations

16.

Benson, Jacqueline, Kim Campbell, Zhen Guan, et al.. (2000). T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen. Journal of Clinical Investigation. 106(8). 1031–1038. 73 indexed citations

17.

Guan, Zhen, et al.. (1999). Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells. Neurochemistry International. 35(6). 411–422. 6 indexed citations

18.

Jakeman, Lyn B., Ping Wei, Zhen Guan, & Bradford T. Stokes. (1998). Brain-Derived Neurotrophic Factor Stimulates Hindlimb Stepping and Sprouting of Cholinergic Fibers after Spinal Cord Injury. Experimental Neurology. 154(1). 170–184. 183 indexed citations

19.

Christofi, Fievos L., et al.. (1996). Responsiveness to ATP with an increase in intracellular free Ca2+ is not a distinctive feature of calbindin-D28 immunoreactive neurons in myenteric ganglia. Brain Research. 725(2). 241–246. 7 indexed citations

20.

Guan, Zhen, Bradford T. Stokes, James R. Van Brocklyn, & Allan J. Yates. (1992). Gangliosides inhibit platelet-derived growth-factor-stimulated increases in intracellular calcium in Swiss 3T3 cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1136(3). 315–318. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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