Jason G. Kettle

3.4k total citations
61 papers, 1.7k citations indexed

About

Jason G. Kettle is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Jason G. Kettle has authored 61 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Molecular Biology, 25 papers in Organic Chemistry and 20 papers in Oncology. Recurrent topics in Jason G. Kettle's work include HER2/EGFR in Cancer Research (10 papers), Quinazolinone synthesis and applications (10 papers) and Cytokine Signaling Pathways and Interactions (10 papers). Jason G. Kettle is often cited by papers focused on HER2/EGFR in Cancer Research (10 papers), Quinazolinone synthesis and applications (10 papers) and Cytokine Signaling Pathways and Interactions (10 papers). Jason G. Kettle collaborates with scholars based in United Kingdom, United States and France. Jason G. Kettle's co-authors include J. Stephen Clark, Frederick W. Goldberg, Matthew W. D. Perry, Thierry Kogej, Richard A. Ward, Peter Ballard, Donald Ogilvie, Thorsten Nowak, Andy Barker and Emma Williams and has published in prestigious journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and Cancer Research.

In The Last Decade

Jason G. Kettle

55 papers receiving 1.6k citations

Peers

Jason G. Kettle

ONCOL

CTM

Mark E. Bunnage United Kingdom

James J.‐W. Duan United States

John H. Hutchinson United States

Joel C. Barrish United States

Matthew M. Hayward United States

Christian Peifer Germany

Percy H. Carter United States

Richard Labaudinière United States

Andrew S. Tasker United States

Randall W. Hungate United States

Mark E. Bunnage United Kingdom

Jason G. Kettle

1.3k ×1.4

1.7k ×2.0

254 ×0.9

ONCOL

300 ×1.6

CTM

91 ×0.7

Citations per year, relative to Jason G. Kettle Jason G. Kettle (= 1×) peers Mark E. Bunnage

Countries citing papers authored by Jason G. Kettle

Since Specialization

Citations

This map shows the geographic impact of Jason G. Kettle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jason G. Kettle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jason G. Kettle more than expected).

Fields of papers citing papers by Jason G. Kettle

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jason G. Kettle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jason G. Kettle. The network helps show where Jason G. Kettle may publish in the future.

Co-authorship network of co-authors of Jason G. Kettle

This figure shows the co-authorship network connecting the top 25 collaborators of Jason G. Kettle. A scholar is included among the top collaborators of Jason G. Kettle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jason G. Kettle. Jason G. Kettle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Pearson‐Stuttard, Jonathan, et al.. (2025). Metrics that matter: Identifying endpoints for capturing the broad health impacts of prevention of obesity. Diabetes Obesity and Metabolism. 27(11). 6275–6283.

Davies, Gareth M., Tiziana Monteverde, Jonathan Tart, et al.. (2024). High throughput application of the NanoBiT Biochemical Assay for the discovery of selective inhibitors of the interaction of PI3K-p110α with KRAS. SLAS DISCOVERY. 29(8). 100197–100197. 1 indexed citations

Kettle, Jason G., et al.. (2024). Effect of Tether Length on endo/exo Stereoselectivity in Alkene–Arene meta‐Photocycloaddition Reactions towards the Aphidocolin/Stemodin Scaffolds. European Journal of Organic Chemistry. 27(30).

Geeson, Michael B., Thomas V. Murray, Monika Papworth, et al.. (2024). Site‐Specific Quadruple‐Functionalised Antibodies. Angewandte Chemie. 137(5).

Andrews, David, Sabina Cosulich, Nullin Divecha, et al.. (2021). Identification and optimization of a novel series of selective PIP5K inhibitors. Bioorganic & Medicinal Chemistry. 54. 116557–116557. 7 indexed citations

Reddy, Venkatesh Pilla, Rana Anjum, Michael Grondine, et al.. (2020). The Pharmacokinetic–Pharmacodynamic (PKPD) Relationships of AZD3229, a Novel and Selective Inhibitor of KIT, in a Range of Mouse Xenograft Models of GIST. Clinical Cancer Research. 26(14). 3751–3759. 9 indexed citations

Grimster, Neil P., Lisa Drew, Stephen E. Fawell, et al.. (2020). Abstract A56: Releasing the brake on T-cell activation through inhibition of HPK1. Cancer Immunology Research. 8(3_Supplement). A56–A56. 1 indexed citations

Kettle, Jason G. & David M. Wilson. (2016). Standing on the shoulders of giants: a retrospective analysis of kinase drug discovery at AstraZeneca. Drug Discovery Today. 21(10). 1596–1608. 15 indexed citations

Goldberg, Frederick W., et al.. (2014). Designing novel building blocks is an overlooked strategy to improve compound quality. Drug Discovery Today. 20(1). 11–17. 158 indexed citations

10.

Barlaam, Bernard, Judith Anderton, Peter Ballard, et al.. (2013). Discovery of AZD8931, an Equipotent, Reversible Inhibitor of Signaling by EGFR, HER2, and HER3 Receptors. ACS Medicinal Chemistry Letters. 4(8). 742–746. 31 indexed citations

11.

Barlaam, Bernard, Richard Ducray, Christine Lambert‐van der Brempt, et al.. (2011). Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series. Bioorganic & Medicinal Chemistry Letters. 21(8). 2207–2211. 26 indexed citations

12.

Bardelle, Catherine, Darren A.E. Cross, Sara Davenport, et al.. (2008). Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines. Bioorganic & Medicinal Chemistry Letters. 18(9). 2776–2780. 49 indexed citations

13.

Ducray, Richard, et al.. (2007). Novel 3-alkoxy-1H-pyrazolo[3,4-d]pyrimidines as EGFR and erbB2 receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 18(3). 959–962. 70 indexed citations

14.

Ballard, Peter, Bernard Barlaam, Robert H. Bradbury, et al.. (2007). Neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase. Bioorganic & Medicinal Chemistry Letters. 17(22). 6326–6329. 23 indexed citations

15.

Barlaam, Bernard, Peter Ballard, Robert H. Bradbury, et al.. (2007). A new series of neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase. Bioorganic & Medicinal Chemistry Letters. 18(2). 674–678. 18 indexed citations

16.

Ballard, Peter, Robert H. Bradbury, Craig S. Harris, et al.. (2006). Inhibitors of epidermal growth factor receptor tyrosine kinase: Optimisation of potency and in vivo pharmacokinetics. Bioorganic & Medicinal Chemistry Letters. 16(18). 4908–4912. 29 indexed citations

17.

Ballard, Peter, Robert H. Bradbury, Laurent Hennequin, et al.. (2005). 5-Substituted 4-anilinoquinazolines as potent, selective and orally active inhibitors of erbB2 receptor tyrosine kinase. Bioorganic & Medicinal Chemistry Letters. 15(19). 4226–4229. 31 indexed citations

18.

Ballard, Peter, Robert H. Bradbury, Craig S. Harris, et al.. (2005). Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocket. Bioorganic & Medicinal Chemistry Letters. 16(6). 1633–1637. 31 indexed citations

19.

Baxter, Andrew, Anne Cooper, Eike Floettmann, et al.. (2004). Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 14(11). 2817–2822. 70 indexed citations

20.

Kettle, Jason G., et al.. (2003). N-Benzylindole-2-carboxylic acids: potent functional antagonists of the CCR2b chemokine receptor. Bioorganic & Medicinal Chemistry Letters. 14(2). 405–408. 24 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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