Angela Cacace

3.1k total citations · 1 hit paper
35 papers, 2.1k citations indexed

About

Angela Cacace is a scholar working on Molecular Biology, Physiology and Oncology. According to data from OpenAlex, Angela Cacace has authored 35 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 6 papers in Physiology and 5 papers in Oncology. Recurrent topics in Angela Cacace's work include Alzheimer's disease research and treatments (6 papers), Protein Kinase Regulation and GTPase Signaling (5 papers) and Genetics and Neurodevelopmental Disorders (5 papers). Angela Cacace is often cited by papers focused on Alzheimer's disease research and treatments (6 papers), Protein Kinase Regulation and GTPase Signaling (5 papers) and Genetics and Neurodevelopmental Disorders (5 papers). Angela Cacace collaborates with scholars based in United States, Germany and Italy. Angela Cacace's co-authors include I. Bernard Weinstein, Deborah K. Morrison, Regina M. Santella, Wei Jiang, Marc Therrien, Neil R. Michaud, Gerald M. Rubin, Edward K. Han, Scott M. Kahn and Yikai Zhang and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and PLoS ONE.

In The Last Decade

Angela Cacace

33 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene

2018 335 citations X. Shawn Liu, Hao Wu et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Angela Cacace United States	21	1.5k	479	291	230	192	35	2.1k
Wenhui Qiao United States	19	1.1k 0.7×	592 1.2×	413 1.4×	228 1.0×	220 1.1×	20	1.8k
Jacqueline L. Vanderluit Canada	25	1.2k 0.8×	354 0.7×	234 0.8×	366 1.6×	207 1.1×	33	1.8k
Stefan Berger Germany	22	800 0.5×	341 0.7×	306 1.1×	375 1.6×	85 0.4×	43	1.8k
Toshiyuki Araki Japan	27	2.7k 1.7×	605 1.3×	229 0.8×	285 1.2×	247 1.3×	42	3.2k
Markus Reschke Austria	16	938 0.6×	542 1.1×	112 0.4×	195 0.8×	129 0.7×	31	1.7k
Daisuke Yamada Japan	22	1.4k 0.9×	556 1.2×	295 1.0×	104 0.5×	97 0.5×	65	2.2k
Yetao Jin United States	17	1.5k 0.9×	731 1.5×	226 0.8×	261 1.1×	207 1.1×	17	1.9k
Andrew J. H. Smith United Kingdom	16	1.3k 0.8×	241 0.5×	129 0.4×	575 2.5×	170 0.9×	19	2.0k
Francisco Cruzalegui France	25	2.0k 1.3×	472 1.0×	210 0.7×	415 1.8×	399 2.1×	51	2.9k
Sheila Harroch France	28	1.2k 0.8×	406 0.8×	149 0.5×	334 1.5×	430 2.2×	40	2.2k

Countries citing papers authored by Angela Cacace

Since Specialization

Citations

This map shows the geographic impact of Angela Cacace's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Angela Cacace with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Angela Cacace more than expected).

Fields of papers citing papers by Angela Cacace

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Angela Cacace. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Angela Cacace. The network helps show where Angela Cacace may publish in the future.

Co-authorship network of co-authors of Angela Cacace

This figure shows the co-authorship network connecting the top 25 collaborators of Angela Cacace. A scholar is included among the top collaborators of Angela Cacace based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Angela Cacace. Angela Cacace is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Smits, Lisa, Yi Zhang, Claire Woodward, et al.. (2025). First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of ARV-102, a PROTAC LRRK2 degrader, in healthy volunteers. Parkinsonism & Related Disorders. 134. 107624–107624. 2 indexed citations

Krukowski, Karen, Sarah Barker, Chao Wang, et al.. (2024). Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury. Molecular Neurodegeneration. 19(1). 51–51. 11 indexed citations

Hickey, Christopher M., Katherine M. Digianantonio, Kurt Zimmermann, et al.. (2024). Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nature Structural & Molecular Biology. 31(2). 311–322. 29 indexed citations

Hickey, Christopher M., et al.. (2024). New therapies on the horizon: Targeted protein degradation in neuroscience. Cell chemical biology. 31(9). 1688–1698. 12 indexed citations

Krzisch, Marine, Hao Wu, Bingbing Yuan, et al.. (2022). Fragile X Syndrome Patient–Derived Neurons Developing in the Mouse Brain Show FMR1-Dependent Phenotypes. Biological Psychiatry. 93(1). 71–81.

Hagedorn, Peter, Jeffrey M. Brown, Amy Easton, et al.. (2022). Acute Neurotoxicity of Antisense Oligonucleotides After Intracerebroventricular Injection Into Mouse Brain Can Be Predicted from Sequence Features. Nucleic Acid Therapeutics. 32(3). 151–162. 36 indexed citations

Rojas, Luis Alejandro, Ning Shen, Alan P. Robertson, et al.. (2020). p38α Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy. Journal of Pharmacology and Experimental Therapeutics. 374(3). 489–498. 34 indexed citations

Graef, John D., Hao Wu, Carrie Ng, et al.. (2019). Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons. European Journal of Neuroscience. 51(10). 2143–2157. 26 indexed citations

Liu, X. Shawn, Hao Wu, Marine Krzisch, et al.. (2018). Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell. 172(5). 979–992.e6. 335 indexed citations breakdown →

10.

Hunihan, Lisa, Jeffrey M. Brown, Angela Cacace, Alda Fernandes, & Andrea D. Weston. (2017). Generation of a clonal induced pluripotent stem cell (iPSC) line expressing the mutant MECP2 allele from a Rett Syndrome patient fibroblast line. Stem Cell Research. 20. 67–69. 5 indexed citations

11.

Cacace, Angela, Martina Sboarina, Thibaut Vazeille, & Pierre Sonveaux. (2016). Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism. Oncogene. 36(15). 2074–2084. 62 indexed citations

12.

Kiefer, Susan E., ChiehYing Chang, Mian Gao, et al.. (2014). The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor. Acta Crystallographica Section F Structural Biology Communications. 70(2). 173–181. 20 indexed citations

13.

Balu, Darrick T., Alo C. Basu, John Corradi, Angela Cacace, & Joseph T. Coyle. (2011). The NMDA receptor co-agonists, d-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex. Neurobiology of Disease. 45(2). 671–682. 74 indexed citations

14.

Cacace, Angela, et al.. (2008). Characterization of the 5-HT2b Receptor in Evaluation of Aequorin Detection of Calcium Mobilization for Miniaturized GPCR High-Throughput Screening. SLAS DISCOVERY. 13(6). 486–493. 16 indexed citations

15.

Zhu, Zhengrong, Jeremy Stewart, John J. Herbst, et al.. (2007). Use of Cryopreserved Transiently Transfected Cells in High-Throughput Pregnane X Receptor Transactivation Assay. SLAS DISCOVERY. 12(2). 248–254. 19 indexed citations

16.

Johnson, Stephen R., Ramesh Padmanabha, Wayne Vaccaro, et al.. (2007). A Simple Strategy for Mitigating the Effect of Data Variability on the Identification of Active Chemotypes from High-Throughput Screening Data. SLAS DISCOVERY. 12(2). 276–284. 2 indexed citations

17.

Barber, Lauren E., et al.. (2004). Adjunct Automation to the Cellmate™ Cell Culture Robot. JALA Journal of the Association for Laboratory Automation. 9(4). 209–217. 5 indexed citations

18.

Cacace, Angela, Martyn Banks, Timothy Spicer, Francesca Civoli, & John B. Watson. (2003). An ultra-HTS process for the identification of small molecule modulators of orphan G-protein-coupled receptors. Drug Discovery Today. 8(17). 785–792. 23 indexed citations

19.

Cacace, Angela, Marius Ueffing, Edward K. Han, Dieter Marmé, & I. Bernard Weinstein. (1998). Overexpression of PKCɛ in R6 fibroblasts causes increased production of active TGFβ. Journal of Cellular Physiology. 175(3). 314–322. 25 indexed citations

20.

Cacace, Angela, et al.. (1995). Overexpression of protein kinase C β1 in the SW480 colon cancer cell line growth suppression. Carcinogenesis. 16(5). 1121–1126. 36 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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