Jonathan C. O’Connell

1.3k citations
18 papers · 585 · h-index 13

Impact in

  • Cellular and Molecular Neuroscience top 10%
    • Neuropeptides and Animal Physiology
  • Molecular Biology
    • Receptor Mechanisms and Signaling
    • Phosphodiesterase function and regulation
    • Pharmacological Receptor Mechanisms and Effects
    • Epigenetics and DNA Methylation
    • Cancer-related gene regulation
    • Chemical Synthesis and Analysis

Papers in

  • Molecular Biology 14
    • Receptor Mechanisms and Signaling 6
    • Chemical Synthesis and Analysis 3
    • Pharmacological Receptor Mechanisms and Effects 3
    • Phosphodiesterase function and regulation 3
    • Protein Tyrosine Phosphatases 2
  • Cellular and Molecular Neuroscience 6
    • Neuropeptides and Animal Physiology 5
Co-authors
Martyn Banks (10 shared papers)Miles D. Houslay (3 shared papers)Andrew Alt (6 shared papers)Neil T. Burford (5 shared papers)Graeme B. Bolger (2 shared papers)Tom S. Wehrman (3 shared papers)Samuel W. Gerritz (4 shared papers)John R. Traynor (2 shared papers)
Journals
SLAS DISCOVERY (7 papers)Journal of Medicinal Chemistry (2 papers)Assay and Drug Development Technologies (1 paper)Organic Letters (1 paper)FEBS Letters (1 paper)
Partner nations
United StatesGermanyUnited Kingdom

In The Last Decade

Jonathan C. O’Connell

18 papers receiving 562 citations

Peers

Jonathan C. O’Connell
Comparison fields: 5 of 68
  • Cellular and Molecular Neuroscience 194
  • Molecular Biology 489
  • Pharmacology 113
  • Pharmacology 27
  • Organic Chemistry 65
Replace Saheem A. Zaidi with:
Saheem A. Zaidi United States
Alexandra J. Gadiano United States
Ginny D. Ho United States
Élie Besserer‐Offroy Canada
Beverley Hammond United Kingdom
Mirko Rivara Italy
Dagmar Stropova United States
Andrew D. Gribble United Kingdom
Toyokazu Hiranuma Japan
Jonathan C. O’Connell relative to Saheem A. Zaidi United States Saheem A. Zaidi's profile →
Citations per field
00.5×1.5×2×2.5×
Saheem A. Zaidi · 1×
Citations per year

Countries citing papers authored by Jonathan C. O’Connell

Since Specialization
Citations

This map shows the geographic impact of Jonathan C. O’Connell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jonathan C. O’Connell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jonathan C. O’Connell more than expected).

Fields of papers citing papers by Jonathan C. O’Connell

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jonathan C. O’Connell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jonathan C. O’Connell. The network helps show where Jonathan C. O’Connell may publish in the future.

Co-authors

The 25 scholars most cited alongside Jonathan C. O’Connell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jonathan C. O’Connell Line = papers co-authored together Jonathan C. O’Connell links everyone, so they are left out of the graph.

All Works

18 of 18 papers shown
#Work
1
Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor
Proceedings of the National Academy of Sciences ·Neil T. Burford, Mary J. Clark, Tom S. Wehrman, Samuel W. Gerritz, Martyn Banks, Jonathan C. O’Connell, John R. Traynor, Andrew Alt
2013126
2
The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5)
Biochemical Journal ·Jonathan C. O’Connell, J. Fraser McCALLUM, Ian McPhee, Jill M. WAKEFIELD, Emma S. Houslay, William Wishart, Graeme B. Bolger, Margaret C. Frame, Miles D. Houslay
199687
3
Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1)
Bioorganic & Medicinal Chemistry Letters ·Ashok V. Purandare, Zhong Chen, Tram Huynh, Suhong Pang, Jieping Geng, Wayne Vaccaro, Michael A. Poss, Jonathan C. O’Connell, Kimberly Nowak, Lata Jayaraman
200869
4
Discovery, Synthesis, and Molecular Pharmacology of Selective Positive Allosteric Modulators of the δ-Opioid Receptor
Journal of Medicinal Chemistry ·Neil T. Burford, Kathryn E. Livingston, Meritxell Canals, Molly R. Ryan, Lauren Budenholzer, Ying Han, Yi Shang, John J. Herbst, Jonathan C. O’Connell, Martyn Banks, Litao Zhang, Marta Filizola, Daniel L. Bassoni, Tom S. Wehrman, Arthur Christopoulos, John R. Traynor, Samuel W. Gerritz, Andrew Alt
201560
5
The unique N‐terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains
FEBS Letters ·Matthew Beard, Jonathan C. O’Connell, Graeme B. Bolger, Miles D. Houslay
199956
6
Synthesis of Multifunctional 2-Aminobenzimidazoles on DNA via Iodine-Promoted Cyclization
Organic Letters ·Liqiang Su, Jing Feng, Ting Peng, Jinqiao Wan, Jing Fan, Jin Li, Jonathan C. O’Connell, David R. Lancia, G. Joseph Franklin, Guansai Liu
202035
7
Identification of Selective Agonists and Positive Allosteric Modulators for µ- and δ-Opioid Receptors from a Single High-Throughput Screen
SLAS DISCOVERY ·Neil T. Burford, Tom S. Wehrman, Daniel L. Bassoni, Jonathan C. O’Connell, Martyn Banks, Litao Zhang, Andrew Alt
201428
8
Use of Cryopreserved Transiently Transfected Cells in High-Throughput Pregnane X Receptor Transactivation Assay
SLAS DISCOVERY ·Zhengrong Zhu, Jaime Puglisi, David Connors, Jeremy Stewart, John J. Herbst, Anthony M. Marino, Michael Sinz, Jonathan C. O’Connell, Martyn Banks, Kenneth E.J. Dickinson, Angela Cacace
200719
9
Small Molecule Receptor Protein Tyrosine Phosphatase γ (RPTPγ) Ligands That Inhibit Phosphatase Activity via Perturbation of the Tryptophan–Proline–Aspartate (WPD) Loop
Journal of Medicinal Chemistry ·S. Sheriff, Brett R. Beno, Weixu Zhai, Walter A. Kostich, Patricia A. McDonnell, Kevin Kish, Valentina Goldfarb, Mian Gao, Susan E. Kiefer, Joseph Yanchunas, Yanling Huang, Shuhao Shi, Shirong Zhu, Carolyn D. Dzierba, Joanne J. Bronson, John E. Macor, Kingsley K. Appiah, Ryan S. Westphal, Jonathan C. O’Connell, Samuel W. Gerritz
201118
10
Identification of Small Molecules That Selectively Inhibit Diacylglycerol Lipase–α Activity
SLAS DISCOVERY ·Kingsley K. Appiah, Yuval Blat, Barbara Robertson, Bradley C. Pearce, Donna L. Pedicord, Robert G. Gentles, Xuan‐Chuan Yu, Faika Mseeh, Nghi Nguyen, Jonathan C. Swaffield, David Harden, Ryan S. Westphal, Martyn Banks, Jonathan C. O’Connell
201315
11
Development of Novel, 384-Well High-Throughput Assay Panels for Human Drug Transporters: Drug Interaction and Safety Assessment in Support of Discovery Research
SLAS DISCOVERY ·Huaping Tang, Ding Ren Shen, Yong–Hae Han, Yan Kong, Praveen Balimane, Anthony M. Marino, Mian Gao, Sophie Wu, Dianlin Xie, Matthew G. Soars, Jonathan C. O’Connell, A. David Rodrigues, Litao Zhang, Mary Ellen Cvijic
201313
12
The Impact of Variable Selection Coverage on Detection of Ligands from a DNA-Encoded Library Screen
SLAS DISCOVERY ·Kelly A. McCarthy, G. Joseph Franklin, David R. Lancia, Martin Olbrot, Eneida Pardo, Jonathan C. O’Connell, Christopher S. Kollmann
202012
13
Alternative splicing of the type-IVA cyclic AMP phosphodiesterase gene provides isoform variants with distinct N-terminal domains fused to a common, soluble catalytic unit: ‘designer’ changes in Vmax, stability and membrane association
Biochemical Society Transactions ·Miles D. Houslay, Grant Scotland, L Pooley, Sandra Spence, Ian Wilkinson, Fraser McCallum, Pascale Julien, Graham Rena, Alison M. Michie, Suat Erdoğan, Li‐Fan Zeng, Jonathan C. O’Connell, Edward S. Tobias, Iain MacPhee
199512
14
Development of a High-Throughput Calcium Flux Assay for Identification of All Ligand Types Including Positive, Negative, and Silent Allosteric Modulators for G Protein-Coupled Receptors
Assay and Drug Development Technologies ·Devin J. Noblin, Robert L. Bertekap, Neil T. Burford, Adam Hendricson, Litao Zhang, Ronald J. Knox, Martyn Banks, Jonathan C. O’Connell, Andrew Alt
201211
15
Integrating High-Content Analysis into a Multiplexed Screening Approach to Identify and Characterize GPCR Agonists
SLAS DISCOVERY ·Ying‐Jie Zhu, John B. Watson, Mengjie Chen, Ding Ren Shen, Melissa Yarde, Michele Agler, Neil T. Burford, Andrew Alt, Sukhanya Jayachandra, Mary Ellen Cvijic, Litao Zhang, Alaric J. Dyckman, Jenny Xie, Jonathan C. O’Connell, Martyn Banks, Andrea D. Weston
201410
16
Challenges and Opportunities in Enabling High-Throughput, Miniaturized High Content Screening
Methods in molecular biology ·Debra Nickischer, Lisa Elkin, Normand J. Cloutier, Jonathan C. O’Connell, Martyn Banks, Andrea D. Weston
20178
17
A High-Throughput Screen for Receptor Protein Tyrosine Phosphatase–γ Selective Inhibitors
SLAS DISCOVERY ·Kingsley K. Appiah, Walter A. Kostich, Samuel W. Gerritz, Yanling Huang, Brian D. Hamman, Jason Allen, Wandong Zhang, Thomas H. Lanthorn, Charles F. Albright, Ryan S. Westphal, Martyn Banks, Jonathan C. O’Connell
20115
18
Studying GPCR trafficking using automated HCS tools
Ying‐Jie Zhu, Michele Agler, Andrew Alt, Jonathan C. O’Connell, Martyn Banks, Jenny Xie
20101

About Jonathan C. O’Connell

Jonathan C. O’Connell is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Immunology, Organic Chemistry and Pharmacology, having authored 18 papers that have together received 585 indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (6 papers), Neuropeptides and Animal Physiology (5 papers), Chemical Synthesis and Analysis (3 papers), Pharmacological Receptor Mechanisms and Effects (3 papers), Phosphodiesterase function and regulation (3 papers), Protein Tyrosine Phosphatases (2 papers), Galectins and Cancer Biology (2 papers) and Pharmacogenetics and Drug Metabolism (2 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (194 citations), Molecular Biology (489 citations), Pharmacology (113 citations), Pharmacology (27 citations) and Organic Chemistry (65 citations). Jonathan C. O’Connell has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Martyn Banks, Miles D. Houslay, Andrew Alt, Neil T. Burford, Graeme B. Bolger, Tom S. Wehrman, Samuel W. Gerritz, John R. Traynor, Mary J. Clark and Matthew Beard. Their work appears in journals such as SLAS DISCOVERY, Journal of Medicinal Chemistry, Assay and Drug Development Technologies, Organic Letters and FEBS Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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