Douglas Brown

2.1k citations

29 papers · 1.8k indexed · 1 hit paper · h-index 20

Co-authors: Erwin London Rolf Schroeder Gerald L. Waneck John L. Middlebrook Ranjan Banerjee Eranthie Weerapana Brian S. J. Blagg George Vielhauer
Topics: Heat shock proteins research (5 papers)Protein Structure and Dynamics (3 papers)Botulinum Toxin and Related Neurological Disorders (3 papers)
Cited by: Cell Biology Molecular Biology Immunology
Journals: Proceedings of the National Academy of Sciences Journal of the American Chemical Society Nature Communications
Partner nations: United States United Kingdom

In The Last Decade

Douglas Brown

29 papers receiving 1.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior.

1994 592 citations Rolf Schroeder, Erwin London et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Douglas Brown

Since Specialization

Citations

This map shows the geographic impact of Douglas Brown's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas Brown with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas Brown more than expected).

Fields of papers citing papers by Douglas Brown

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas Brown. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas Brown. The network helps show where Douglas Brown may publish in the future.

Co-authorship network of co-authors of Douglas Brown

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas Brown. A scholar is included among the top collaborators of Douglas Brown based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas Brown. Douglas Brown is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Impact of preoperative endoscopic procedures on adverse event rates after surgical resection for main-duct and mixed-type intraductal papillary mucinous neoplasms (IPMNs) 2023 ·Pancreatology ·(unknown),(unknown),Carlos Fernández‐del Castillo,(unknown),Douglas Brown,Mari Mino–Kenudson,Kumar Krishnan,Brenna Casey,Kelly J. Lafaro,Anne Marie Lennon,Elham Afghani,Yasmin G. Hernandez‐Barco	1
2	High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming 2021 ·Nature Communications ·Guangan Hu,Yang Su,Byong H. Kang,Zhongqi Fan,Ting Dong,Douglas Brown,Jaime H. Cheah,K. Dane Wittrup,Jianzhu Chen	101
3	MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme 2020 ·Nature Communications ·Yingzhong Li,Nikola A. Ivica,Ting Dong,Dimitrios Papageorgiou,Yanpu He,Douglas Brown,Marianna Kleyman,Guangan Hu,Walter W. Chen,Lucas B. Sullivan,Amanda Del Rosario,Paula T. Hammond,Matthew G. Vander Heiden,Jianzhu Chen	32
4	CAR-T cells targeting a nucleophosmin neoepitope exhibit potent specific activity in mouse models of acute myeloid leukaemia 2020 ·Nature Biomedical Engineering ·Guozhu Xie,Nikola A. Ivica,Bin Jia,Yingzhong Li,Han Dong,Yong Liang,Douglas Brown,Rizwan Romee,Jianzhu Chen	58
5	KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90α in Prostate Cancer Cells 2015 ·Molecular Pharmacology ·Weiya Liu,George Vielhauer,Jeffrey M. Holzbeierlein,Huiping Zhao,Suman Ghosh,Douglas Brown,Eugene Lee,Brian S. J. Blagg	33
6	Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors 2014 ·Bioorganic & Medicinal Chemistry ·Bhaskar Reddy Kusuma,Anuj Khandelwal,(unknown),Douglas Brown,Weiya Liu,George Vielhauer,Jeffrey M. Holzbeierlein,Brian S. J. Blagg	46
7	Development of a High-Throughput Screening Cancer Cell-Based Luciferase Refolding Assay for Identifying Hsp90 Inhibitors 2013 ·Assay and Drug Development Technologies ·(unknown),(unknown),(unknown),Douglas Brown,Huiping Zhao,Bhaskar Reddy Kusuma,Roger A. Rajewski,Brian S. J. Blagg,Robert L. Matts,Jeffrey M. Holzbeierlein,George Vielhauer	12
8	1,3,5-Triazine as a Modular Scaffold for Covalent Inhibitors with Streamlined Target Identification 2013 ·Journal of the American Chemical Society ·Ranjan Banerjee,Nicholas J. Pace,Douglas Brown,Eranthie Weerapana	88
9	Recent Developments in the Synthesis of Bioactive 2,4,6-Trisubstituted 1,3,5-Triazines 2013 ·Synlett ·Eranthie Weerapana,Ranjan Banerjee,Douglas Brown	20
10	Engineering an Antibiotic to Fight Cancer: Optimization of the Novobiocin Scaffold to Produce Anti-proliferative Agents 2011 ·Journal of Medicinal Chemistry ·Huiping Zhao,Alison C. Donnelly,Bhaskar Reddy Kusuma,Gary Brandt,Douglas Brown,Roger A. Rajewski,George Vielhauer,Jeffrey M. Holzbeierlein,Mark S. Cohen,Brian S. J. Blagg	147
11	Atonal Homolog 1 Is Required for Growth and Differentiation Effects of Notch/γ-Secretase Inhibitors on Normal and Cancerous Intestinal Epithelial Cells 2010 ·Gastroenterology ·Avedis Kazanjian,Taeko K. Noah,Douglas Brown,Jarred Burkart,Noah F. Shroyer	70
12	268 Atonal Homolog 1 (ATOH1) is Essential for Growth and Differentiation Effects of Notch/γ Secretase Inhibitors on Normal and Cancerous Intestinal Epithelial Cells 2010 ·Gastroenterology ·Avedis Kazanjian,Taeko K. Noah,Douglas Brown,Jarred Burkart,Noah F. Shroyer	2
13	Roads from vaccines to therapies 2004 ·Movement Disorders ·Leonard A. Smith,(unknown),Vicki A. Montgomery,Douglas Brown,Saif Ahmed,Theresa J. Smith	24
14	Pentoxifylline fails to improve organ dysfunction and survival when used in the resuscitation of a porcine model of haemorrhage and abdominal sepsis 2000 ·Resuscitation ·(unknown),Douglas Brown,(unknown),P Watkins	5
15	A PORCINE MODEL OF SEPSIS RESULTING FROM THE COMBINED INSULTS OF HEMORRHAGE AND PERITONITIS 2000 ·Shock ·(unknown),(unknown),Douglas Brown,(unknown),P Watkins	12
16	Identification and Characterization of a Neutralizing Monoclonal Antibody Against Botulinum Neurotoxin, Serotype F, Following Vaccination With Active Toxin 1997 ·Hybridoma ·Douglas Brown,(unknown),James J. Schmidt	15
17	Protective vaccination with a recombinant fragment of Clostridium botulinum neurotoxin serotype A expressed from a synthetic gene in Escherichia coli 1995 ·Infection and Immunity ·(unknown),(unknown),Douglas Brown,John L. Middlebrook	129
18	Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior.breakdown → 1994 ·Proceedings of the National Academy of Sciences ·Rolf Schroeder,Erwin London,Douglas Brown	592
19	Cloning of the filamentous hemagglutinin of Bordetella pertussis and its expression in Escherichia coli 1987 ·Infection and Immunity ·Douglas Brown,C D Parker	27
20	l-Tryptophan administration potentiates serotonin-dependent myoclonic behavior in the rat 1980 ·Neuropharmacology ·Douglas Brown,John H. Growdon	3

About Douglas Brown

Douglas Brown is a scholar working on Critical Care and Intensive Care Medicine, Microbiology and Toxicology, having authored 29 papers that have together received 1.8k indexed citations. Recurring topics across this work include Heat shock proteins research (5 papers), Protein Structure and Dynamics (3 papers) and Botulinum Toxin and Related Neurological Disorders (3 papers). The work is most often cited by research in Cell Biology (348 citations), Molecular Biology (1.1k citations) and Immunology (213 citations). Douglas Brown has collaborated with scholars based in United States and United Kingdom. Frequent co-authors include Erwin London, Rolf Schroeder, Gerald L. Waneck, John L. Middlebrook, Ranjan Banerjee, Eranthie Weerapana, Brian S. J. Blagg, George Vielhauer, Jeffrey M. Holzbeierlein and Huiping Zhao. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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