Tom van der Poll

116.0k total citations · 20 hit papers
876 papers, 71.6k citations indexed

About

Tom van der Poll is a scholar working on Epidemiology, Immunology and Hematology. According to data from OpenAlex, Tom van der Poll has authored 876 papers receiving a total of 71.6k indexed citations (citations by other indexed papers that have themselves been cited), including 401 papers in Epidemiology, 375 papers in Immunology and 139 papers in Hematology. Recurrent topics in Tom van der Poll's work include Immune Response and Inflammation (272 papers), Sepsis Diagnosis and Treatment (202 papers) and Blood Coagulation and Thrombosis Mechanisms (118 papers). Tom van der Poll is often cited by papers focused on Immune Response and Inflammation (272 papers), Sepsis Diagnosis and Treatment (202 papers) and Blood Coagulation and Thrombosis Mechanisms (118 papers). Tom van der Poll collaborates with scholars based in Netherlands, United States and Canada. Tom van der Poll's co-authors include Marcel Levi, Derek C. Angus, Steven M. Opal, Sandrine Florquin, Manu Shankar‐Hari, W. Joost Wiersinga, Jean‐Louis Vincent, John C. Marshall, Gordon R. Bernard and Michael Bauer and has published in prestigious journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Tom van der Poll

869 papers receiving 70.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

2016 17.0k citations Tom van der Poll et al. profile →
Severe Sepsis and Septic Shock

2013 2.8k citations Tom van der Poll et al. profile →
The immunopathology of sepsis and potential therapeutic targets

2017 1.3k citations Tom van der Poll, Brendon P. Scicluna et al. profile →
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

2007 1.1k citations Tom van der Poll et al. profile →
Inflammation and coagulation

2010 716 citations Tom van der Poll et al. Critical Care Medicine profile →
Sepsis: a roadmap for future research

2015 714 citations Tom van der Poll et al. profile →
Bidirectional Relation Between Inflammation and Coagulation

2004 687 citations Tom van der Poll et al. profile →
The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

2015 607 citations Tim J. Schuijt, Jacqueline M. Lankelma et al. Gut profile →
Coagulation and sepsis

2016 557 citations Tom van der Poll et al. profile →
Pathogenesis, treatment, and prevention of pneumococcal pneumonia

2009 539 citations Tom van der Poll et al. profile →
The immunology of sepsis

2021 516 citations Tom van der Poll, W. Joost Wiersinga et al. profile →
Activation of Coagulation after Administration of Tumor Necrosis Factor to Normal Subjects

1990 514 citations Tom van der Poll, Sander J. H. van Deventer et al. profile →
Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit

2010 499 citations Tom van der Poll et al. profile →
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

2016 438 citations Brendon P. Scicluna, Olaf L. Cremer et al. profile →
Pneumonia

2021 411 citations Antoní Torres, Catia Cillóniz et al. Nature Reviews Disease Primers profile →
Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis

2016 345 citations Lonneke A. van Vught, Brendon P. Scicluna et al. profile →
Diagnosis and management of sepsis‐induced coagulopathy and disseminated intravascular coagulation

2019 330 citations Tom van der Poll et al. profile →
Sepsis-Induced Immunosuppression

2021 200 citations Tom van der Poll et al. profile →
A guide to immunotherapy for COVID-19

2022 191 citations Lennie Derde, W. Joost Wiersinga et al. profile →
The pathophysiology of sepsis and precision-medicine-based immunotherapy

2024 158 citations Tom van der Poll, Alexander P. J. Vlaar et al. profile →

Peers

Countries citing papers authored by Tom van der Poll

Since Specialization

Citations

This map shows the geographic impact of Tom van der Poll's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tom van der Poll with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tom van der Poll more than expected).

Fields of papers citing papers by Tom van der Poll

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tom van der Poll. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tom van der Poll. The network helps show where Tom van der Poll may publish in the future.

Co-authorship network of co-authors of Tom van der Poll

This figure shows the co-authorship network connecting the top 25 collaborators of Tom van der Poll. A scholar is included among the top collaborators of Tom van der Poll based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tom van der Poll. Tom van der Poll is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Effect of the gut microbiota-derived tryptophan metabolite indole-3-acetic acid in pneumonia 2025 ·Nature Communications ·Robert F. J. Kullberg, (unknown), Bastiaan W. Haak, (unknown), Joe M. Butler, (unknown), Tjitske S. R. van Engelen, Jonne J. Sikkens, Marije K. Bomers, Antoine Lefèvre, Olaf L. Cremer, Joris J. T. H. Roelofs, Bruno Sovran, René van den Wijngaard, Alex F. de Vos, Wouter J. de Jonge, Tom van der Poll, W. Joost Wiersinga	0
2	Temporal robustness of biomarker-based classification algorithms for sepsis 2025 ·Intensive Care Medicine ·Emma Rademaker, Rombout B. E. van Amstel, Said el Bouhaddani, Marc J. M. Bonten, Lennie Derde, (unknown), Tom van der Poll, Lieuwe D. J. Bos, Harm‐Jan de Grooth, Olaf L. Cremer	1
3	Pathogen-specific host response in critically ill patients with blood stream infections: a nested case–control study 2025 ·EBioMedicine ·Joe M. Butler, Hessel Peters‐Sengers, Tom D. Y. Reijnders, Tjitske S. R. van Engelen, Fabrice Uhel, Lonneke A. van Vught, Marcus J. Schultz, Pierre‐François Laterre, Bruno François, Miguel Sánchez García, Eleuterio Lombardo, Timothy E. Sweeney, Marc J. M. Bonten, (unknown), Dayle Sampson, (unknown), Thomas D. Yager, Olaf L. Cremer, Brendon P. Scicluna, Tom van der Poll	1
4	Aiming for precision: personalized medicine through sepsis subtyping 2024 ·Burns & Trauma ·(unknown), W. Joost Wiersinga, Tom van der Poll	4
5	Dysregulation of Host–Pathogen Interactions in Sepsis: Host-Related Factors 2024 ·Seminars in Respiratory and Critical Care Medicine ·(unknown), W. Joost Wiersinga, Tom van der Poll	1
6	Clinical Subtype Trajectories in Sepsis Patients Admitted to the ICU: A Secondary Analysis of an Observational Study 2024 ·Critical Care Explorations ·Marleen A. Slim, Rombout B. E. van Amstel, Marcella C.A. Müller, Olaf L. Cremer, Alexander P. J. Vlaar, Tom van der Poll, W. Joost Wiersinga, Christopher Seymour, Lonneke A. van Vught	2
7	The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia 2024 ·American Journal of Respiratory and Critical Care Medicine ·Osoul Chouchane, Alex R. Schuurman, Tom D. Y. Reijnders, Hessel Peters‐Sengers, Joe M. Butler, Fabrice Uhel, Marcus J. Schultz, Marc J. M. Bonten, Olaf L. Cremer, Carolyn S. Calfee, Michael A. Matthay, Raymond J. Langley, Narges Alipanah, Stephen F. Kingsmore, Angela J. Rogers, Michel van Weeghel, Frédéric M. Vaz, Tom van der Poll	15
8	Persistent alveolar inflammatory response in critically ill patients with COVID-19 is associated with mortality 2023 ·Thorax ·Justin de Brabander, L.S. Boers, Robert F. J. Kullberg, (unknown), Esther J. Nossent, Leo Heunks, Alexander P. J. Vlaar, Peter I. Bonta, Marcus J. Schultz, Tom van der Poll, JanWillem Duitman, Lieuwe D. J. Bos, (unknown)	15
9	Host Response Changes and Their Association with Mortality in COVID-19 Patients with Lymphopenia 2023 ·American Journal of Respiratory and Critical Care Medicine ·(unknown), Brent Appelman, Justin de Brabander, Rombout B. E. van Amstel, (unknown), Osoul Chouchane, Tom D. Y. Reijnders, Alex R. Schuurman, (unknown), (unknown), Renée A. Douma, Lieuwe D. J. Bos, W. Joost Wiersinga, Hessel Peters‐Sengers, Tom van der Poll	5
10	Immunomodulation and endothelial barrier protection mediate the association between oral imatinib and mortality in hospitalised COVID-19 patients 2022 ·European Respiratory Journal ·Justin de Brabander, (unknown), (unknown), Patrick Smeele, Hessel Peters‐Sengers, JanWillem Duitman, Jurjan Aman, Harm Jan Bogaard, Tom van der Poll, Lieuwe D. J. Bos	19
11	Pneumonia breakdown → 2021 ·Nature Reviews Disease Primers ·Antoní Torres, Catia Cillóniz, Michael S. Niederman, Rosario Menéndez, James D. Chalmers, Richard G. Wunderink, Tom van der Poll	411
12	Biological subphenotypes of acute respiratory distress syndrome may not reflect differences in alveolar inflammation 2021 ·Physiological Reports ·Nanon F. L. Heijnen, Laura A. Hagens, Marry R. Smit, Marcus J. Schultz, Tom van der Poll, Ronny M. Schnabel, Iwan C.C. van der Horst, Robert P. Dickson, Dennis C. J. J. Bergmans, Lieuwe D. J. Bos	25
13	Aging and Microglial Response following Systemic Stimulation with Escherichia coli in Mice 2021 ·Cells ·Inge C.M. Hoogland, (unknown), Joo-Yeon Engelen-Lee, Mercedes Valls Serón, (unknown), David J. van Westerloo, Tom van der Poll, Willem A. van Gool, Diederik van de Beek	6
14	Diabetes Is Not Associated With Increased 90-Day Mortality Risk in Critically Ill Patients With Sepsis 2017 ·Critical Care Medicine ·Lonneke A. van Vught, Rebecca Holman, Evert de Jonge, Nicolette F. de Keizer, Tom van der Poll	39
15	The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia breakdown → 2015 ·Gut ·Tim J. Schuijt, Jacqueline M. Lankelma, Brendon P. Scicluna, Felipe de Sousa e Melo, Joris J. T. H. Roelofs, J. Daan de Boer, Arjan J. Hoogendijk, Regina de Beer, Alex de Vos, Clara Belzer, Willem M. de Vos, Tom van der Poll, W. Joost Wiersinga	607
16	Correction for Pasari et al., Several scales of biodiversity affect ecosystem multifunctionality 2013 ·Proceedings of the National Academy of Sciences ·Weile Wang, Philippe Ciais, Ramakrishna Nemani, Josep G. Canadell, Shilong Piao, Stephen Sitch, Michael A. White, JanWillem Duitman, Marcel Schouten, A.P. de Groot, Keren Borensztajn, Joost Daalhuisen, Sandrine Florquin, Tom van der Poll, C. Arnold Spek	2
17	β2-Glycoprotein I: a novel component of innate immunity 2011 ·Blood ·Çetin Ağar, Philip G. de Groot, Matthias Mörgelin, (unknown), (unknown), Johannes H.M. Levels, Bas de Laat, Rolf T. Urbanus, Heiko Herwald, Tom van der Poll, Joost C.M. Meijers	87
18	Mechanical Ventilation with Lower Tidal Volumes and Positive End-expiratory Pressure Prevents Pulmonary Inflammation in Patients without Preexisting Lung Injury 2008 ·Anesthesiology ·Esther K. Wolthuis, Goda Choi, Mark C. Dessing, Paul Bresser, René Lutter, Misa Dzoljic, Tom van der Poll, Margreeth B. Vroom, Markus W. Hollmann, Marcus J. Schultz	197
19	Antiinflammatory Effects of Salmeterol after Inhalation of Lipopolysaccharide by Healthy Volunteers 2005 ·American Journal of Respiratory and Critical Care Medicine ·Nico A. Maris, Alex F. de Vos, Mark C. Dessing, C. Arnold Spek, René Lutter, Henk M. Jansen, Jaring S. van der Zee, Paul Bresser, Tom van der Poll	103
20	The effect ofPseudomonasexotoxin A on cytokine production in whole blood exposed toPseudomonas aeruginosa 2000 ·FEMS Immunology & Medical Microbiology ·Marc J. Schultz, Peter Speelman, (unknown), C. Erik Hack, Sander J. H. van Deventer, Tom van der Poll	25

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