Kevin J. Tracey

103.6k total citations · 42 hit papers
501 papers, 79.9k citations indexed

About

Kevin J. Tracey is a scholar working on Molecular Biology, Neurology and Immunology. According to data from OpenAlex, Kevin J. Tracey has authored 501 papers receiving a total of 79.9k indexed citations (citations by other indexed papers that have themselves been cited), including 183 papers in Molecular Biology, 179 papers in Neurology and 161 papers in Immunology. Recurrent topics in Kevin J. Tracey's work include Advanced Glycation End Products research (148 papers), Vagus Nerve Stimulation Research (147 papers) and Immune Response and Inflammation (109 papers). Kevin J. Tracey is often cited by papers focused on Advanced Glycation End Products research (148 papers), Vagus Nerve Stimulation Research (147 papers) and Immune Response and Inflammation (109 papers). Kevin J. Tracey collaborates with scholars based in United States, Sweden and United Kingdom. Kevin J. Tracey's co-authors include Anthony Cerami, Haichao Wang, Jan Andersson, Valentin A. Pavlov, Christopher J. Czura, Michael T. Lotze, Mahendar Ochani, Sangeeta S. Chavan, Huan Yang and Mauricio Rosas‐Ballina and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Kevin J. Tracey

491 papers receiving 78.3k citations

Hit Papers

Vagus nerve stimulation attenuates the systemic inflamma... 1986 2026 1999 2012 2000 1999 2002 2002 1986 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
    2000 3.1k citations Haichao Wang, Kevin J. Tracey et al. profile →
  2. HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
    1999 2.8k citations Haichao Wang, Huan Yang et al. profile →
  3. The inflammatory reflex
    2002 2.7k citations Kevin J. Tracey profile →
  4. Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
    2002 2.6k citations Mahendar Ochani, Jian Hua Li et al. profile →
  5. Shock and Tissue Injury Induced by Recombinant Human Cachectin
    1986 2.1k citations Kevin J. Tracey et al. profile →
  6. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
    2005 2.1k citations Kevin J. Tracey et al. profile →
  7. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
    1987 2.0k citations Kevin J. Tracey et al. profile →
  8. High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes
    2000 1.2k citations Jan Andersson, Haichao Wang et al. The Journal of Experimental Medicine profile →
  9. HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection
    2011 1.2k citations Jan Andersson, Kevin J. Tracey profile →
  10. Physiology and immunology of the cholinergic antiinflammatory pathway
    2007 1.2k citations Kevin J. Tracey Journal of Clinical Investigation profile →
  11. Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit
    2011 1.1k citations Mauricio Rosas‐Ballina, Peder S. Olofsson et al. profile →
  12. Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.
    1991 962 citations Kevin J. Tracey et al. Journal of Clinical Investigation profile →
  13. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
    2005 944 citations Huan Yang, Jianhua Li et al. The Journal of Experimental Medicine profile →
  14. Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
    2004 943 citations Hong Liao, Mahendar Ochani et al. profile →
  15. Reversing established sepsis with antagonists of endogenous high-mobility group box 1
    2003 942 citations Huan Yang, Mahendar Ochani et al. Proceedings of the National Academy of Sciences profile →
  16. TUMOR NECROSIS FACTOR: A Pleiotropic Cytokine and Therapuetic Target
    1994 884 citations Kevin J. Tracey et al. profile →
  17. MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia
    1993 861 citations Kevin J. Tracey et al. profile →
  18. Reflex control of immunity
    2009 826 citations Kevin J. Tracey profile →
  19. Endogenous HMGB1 regulates autophagy
    2010 778 citations Marco E. Bianchi, Kevin J. Tracey et al. profile →
  20. Sepsis: a roadmap for future research
    2015 714 citations Kevin J. Tracey et al. profile →
  21. Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis
    2016 706 citations Sangeeta S. Chavan, Yaakov A. Levine et al. Proceedings of the National Academy of Sciences profile →
  22. HMGB1 SIGNALS THROUGH TOLL-LIKE RECEPTOR (TLR) 4 AND TLR2
    2006 696 citations Haichao Wang, Christopher J. Czura et al. profile →
  23. Tumor Necrosis Factor, Other Cytokines and Disease
    1993 688 citations Kevin J. Tracey et al. profile →
  24. The vagus nerve and the inflammatory reflex—linking immunity and metabolism
    2012 671 citations Valentin A. Pavlov, Kevin J. Tracey profile →
  25. A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
    2010 645 citations Huan Yang, Haichao Wang et al. Proceedings of the National Academy of Sciences profile →
  26. Novel role of PKR in inflammasome activation and HMGB1 release
    2012 632 citations Ben Lü, Jianhua Li et al. profile →
  27. Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation.
    1988 612 citations Kevin J. Tracey et al. The Journal of Experimental Medicine profile →
  28. Cutting Edge: HMG-1 as a Mediator of Acute Lung Inflammation
    2000 610 citations Haichao Wang, Kevin J. Tracey et al. profile →
  29. Spinal Glia and Proinflammatory Cytokines Mediate Mirror-Image Neuropathic Pain in Rats
    2003 577 citations Kevin J. Tracey et al. profile →
  30. The Cholinergic Anti-inflammatory Pathway: A Missing Link in Neuroimmunomodulation
    2003 563 citations Valentin A. Pavlov, Christopher J. Czura et al. Molecular Medicine profile →
  31. Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
    2012 561 citations Emilie Vénéreau, Maura Casalgrandi et al. The Journal of Experimental Medicine profile →
  32. Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia
    2008 551 citations Mauricio Rosas‐Ballina, Mahendar Ochani et al. Proceedings of the National Academy of Sciences profile →
  33. Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis
    2006 536 citations Jared M. Huston, Mahendar Ochani et al. The Journal of Experimental Medicine profile →
  34. Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.
    1989 522 citations Kevin J. Tracey et al. The Journal of Experimental Medicine profile →
  35. Sepsis definitions: time for change
    2013 517 citations Kevin J. Tracey et al. profile →
  36. Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation
    2002 510 citations Luis Ulloa, Mahendar Ochani et al. Proceedings of the National Academy of Sciences profile →
  37. Sepsis: Current Dogma and New Perspectives
    2014 492 citations Kevin J. Tracey et al. profile →
  38. Mechanisms and Therapeutic Relevance of Neuro-immune Communication
    2017 467 citations Sangeeta S. Chavan, Valentin A. Pavlov et al. profile →
  39. The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis
    2013 446 citations Huan Yang, Daniel J. Antoine et al. profile →
  40. A jump-start for electroceuticals
    2013 429 citations Kevin J. Tracey et al. profile →
  41. Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog.
    1987 341 citations Kevin J. Tracey et al. profile →
  42. Glucagon-like peptide-1: a multi-faceted anti-inflammatory agent
    2023 153 citations Syed Faizan Mehdi, Kevin J. Tracey et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Kevin J. Tracey United States 135 25.7k 23.2k 20.8k 17.1k 10.2k 501 79.9k
Anthony Cerami United States 135 18.8k 0.7× 20.7k 0.9× 3.2k 0.2× 10.9k 0.6× 10.8k 1.1× 514 76.7k
Haichao Wang United States 85 13.3k 0.5× 10.9k 0.5× 6.0k 0.3× 10.9k 0.6× 4.0k 0.4× 295 33.9k
Ann Marie Schmidt United States 113 13.3k 0.5× 7.4k 0.3× 4.2k 0.2× 27.6k 1.6× 4.2k 0.4× 395 49.7k
Jan Andersson Sweden 109 13.9k 0.5× 20.4k 0.9× 3.5k 0.2× 10.0k 0.6× 7.6k 0.7× 571 48.5k
Charles N. Serhan United States 155 23.1k 0.9× 23.9k 1.0× 2.6k 0.1× 3.3k 0.2× 7.6k 0.7× 625 82.0k
Timothy R. Billiar United States 122 19.5k 0.8× 14.0k 0.6× 2.1k 0.1× 4.6k 0.3× 7.7k 0.8× 781 57.3k
Charles A. Dinarello United States 174 36.8k 1.4× 47.0k 2.0× 3.8k 0.2× 1.4k 0.1× 15.9k 1.6× 873 108.0k
Peter P. Nawroth Germany 95 9.8k 0.4× 6.5k 0.3× 2.7k 0.1× 11.1k 0.6× 4.0k 0.4× 494 36.3k
Claudio Franceschi Italy 110 23.8k 0.9× 11.6k 0.5× 4.4k 0.2× 1.4k 0.1× 7.3k 0.7× 816 62.5k
Eicke Latz Germany 101 32.3k 1.3× 31.6k 1.4× 5.4k 0.3× 1.1k 0.1× 8.9k 0.9× 283 61.2k

Countries citing papers authored by Kevin J. Tracey

Since Specialization
Citations

This map shows the geographic impact of Kevin J. Tracey's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kevin J. Tracey with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kevin J. Tracey more than expected).

Fields of papers citing papers by Kevin J. Tracey

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kevin J. Tracey. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kevin J. Tracey. The network helps show where Kevin J. Tracey may publish in the future.

Co-authorship network of co-authors of Kevin J. Tracey

This figure shows the co-authorship network connecting the top 25 collaborators of Kevin J. Tracey. A scholar is included among the top collaborators of Kevin J. Tracey based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kevin J. Tracey. Kevin J. Tracey is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Wang, Ping, et al.. (2026). Repurposing a detrimental antibody epitope as targeted therapeutics for sepsis and rheumatoid arthritis. Military Medical Research. 12(1). 98–98.
2.
Brines, Michael, Xiangying Xue, Prodyot K. Chatterjee, et al.. (2025). Increased plasma lipopolysaccharide-binding protein and altered inflammatory mediators reveal a pro-inflammatory state in overweight women. BMC Women s Health. 25(1). 57–57. 2 indexed citations
3.
Mehdi, Syed Faizan, Miti Shah, Christine N. Metz, et al.. (2025). Endocrine and metabolic alterations in response to systemic inflammation and sepsis: a review article. Molecular Medicine. 31(1). 16–16. 11 indexed citations
4.
Natarajan, Chandramohan, et al.. (2024). Electrical stimulation of the vagus nerve ameliorates inflammation and disease activity in a rat EAE model of multiple sclerosis. Proceedings of the National Academy of Sciences. 121(28). e2322577121–e2322577121. 8 indexed citations
5.
Kressel, Adam M., Téa Tsaava, Yaakov A. Levine, et al.. (2020). Identification of a brainstem locus that inhibits tumor necrosis factor. Proceedings of the National Academy of Sciences. 117(47). 29803–29810. 90 indexed citations
6.
Zanos, Theodoros P., Harold Silverman, Todd Levy, et al.. (2018). Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity. Proceedings of the National Academy of Sciences. 115(21). E4843–E4852. 152 indexed citations
7.
Consolim‐Colombo, Fernanda Marciano, Carine Teles Sangaleti, Heno Ferreira Lopes, et al.. (2017). Galantamine alleviates inflammation and insulin resistance in patients with metabolic syndrome in a randomized trial. JCI Insight. 2(14). 66 indexed citations
8.
Li, Wei, Shu Zhu, Jianhua Li, et al.. (2015). Serum Amyloid A Stimulates PKR Expression and HMGB1 Release Possibly through TLR4/RAGE Receptors. Molecular Medicine. 21(1). 515–525. 33 indexed citations
9.
Tang, Yiting, Xin Zhao, Daniel J. Antoine, et al.. (2015). Regulation of Posttranslational Modifications of HMGB1 During Immune Responses. Antioxidants and Redox Signaling. 24(12). 620–634. 110 indexed citations
10.
Lü, Ben, Daniel J. Antoine, Kevin Kwan, et al.. (2014). JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation. Proceedings of the National Academy of Sciences. 111(8). 3068–3073. 298 indexed citations
11.
Parker, Katherine H., Pratima Sinha, Lucas A. Horn, et al.. (2014). HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells. Cancer Research. 74(20). 5723–5733. 208 indexed citations
12.
Antoine, Daniel J., Helena Erlandsson Harris, Jan Andersson, Kevin J. Tracey, & Marco E. Bianchi. (2014). A Systematic Nomenclature for the Redox States of High Mobility Group Box (HMGB) Proteins. Molecular Medicine. 20(1). 135–137. 88 indexed citations
13.
Reardon, Colin, Gordon S. Duncan, Anne Brüstle, et al.. (2013). Lymphocyte-derived ACh regulates local innate but not adaptive immunity. Proceedings of the National Academy of Sciences. 110(4). 1410–1415. 179 indexed citations
14.
Patel, Vivek, Ravikumar Sitapara, Lokesh Sharma, et al.. (2013). High Mobility Group Box–1 Mediates Hyperoxia-Induced Impairment of Pseudomonas aeruginosa Clearance and Inflammatory Lung Injury in Mice. American Journal of Respiratory Cell and Molecular Biology. 48(3). 280–287. 67 indexed citations
15.
Vénéreau, Emilie, Maura Casalgrandi, Milena Schiraldi, et al.. (2012). Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. The Journal of Experimental Medicine. 209(9). 1519–1528. 561 indexed citations breakdown →
16.
Tracey, Kevin J.. (2007). Physiology and immunology of the cholinergic antiinflammatory pathway. Journal of Clinical Investigation. 117(2). 289–296. 1164 indexed citations breakdown →
17.
Huston, Jared M., Mahendar Ochani, Mauricio Rosas‐Ballina, et al.. (2006). Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis. The Journal of Experimental Medicine. 203(7). 1623–1628. 536 indexed citations breakdown →
18.
Friedman, Steven G., Christopher J. Czura, & Kevin J. Tracey. (2003). The gesture life of high mobility group box 1. Current Opinion in Clinical Nutrition & Metabolic Care. 6(3). 283–287. 7 indexed citations
19.
Wang, Haichao, Huan Yang, Christopher J. Czura, Andrew E. Sama, & Kevin J. Tracey. (2001). HMGB1 as a Late Mediator of Lethal Systemic Inflammation. American Journal of Respiratory and Critical Care Medicine. 164(10). 1768–1773. 406 indexed citations
20.
D’Souza, Malcolm J., Carl W. Oettinger, Grace V. Milton, & Kevin J. Tracey. (1999). Prevention of Lethality and Suppression of Proinflammatory Cytokines in Experimental Septic Shock by Microencapsulated CNI-1493. Journal of Interferon & Cytokine Research. 19(10). 1125–1133. 23 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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