Peter Pickkers

37.5k citations

443 papers · 18.8k indexed · 9 hit papers · h-index 73

Impact in

Critical Care and Intensive Care Medicine top 0.02%
- Intensive Care Unit Cognitive Disorders
Nephrology top 0.1%
- Acute Kidney Injury Research

Papers in ⓘ

Epidemiology 146
- Sepsis Diagnosis and Treatment 118
Immunology 102
- Immune Response and Inflammation 72

Co-authors: Matthijs Kox (154 shared papers)Johannes G. van der Hoeven (107 shared papers)Mihai G. Netea (48 shared papers)Mark van den Boogaard (51 shared papers)Lisette Schoonhoven (30 shared papers)Theo van Achterberg (15 shared papers)Leo Koenderman (15 shared papers)Paul Smits (29 shared papers)
Journals: Critical Care (52 papers)Shock (31 papers)Intensive Care Medicine (24 papers)Critical Care Medicine (24 papers)Journal of Critical Care (19 papers)
Partner nations: Netherlands United States Germany

In The Last Decade

Peter Pickkers

434 papers receiving 18.5k citations

Hit Papers

9 papers align trajectories log scale

The pathophysiology of sepsis and precision-medicine-based immunotherapy 2024 · 158 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2024 Nature Immunology
2022 Nature Medicine
2021 Annual Review of Physiology
2021 Intensive Care Medicine
2019 Intensive Care Medicine
2016 Nature Immunology
2015 Journal of the American Society of Nephrology
2013 Shock
2011 Journal of Clinical Investigation

Peers

Countries citing papers authored by Peter Pickkers

Since Specialization

Citations

This map shows the geographic impact of Peter Pickkers's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Peter Pickkers with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Peter Pickkers more than expected).

Fields of papers citing papers by Peter Pickkers

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Peter Pickkers. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Peter Pickkers. The network helps show where Peter Pickkers may publish in the future.

Co-authors

The 25 scholars most cited alongside Peter Pickkers, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Peter Pickkers Line = papers co-authored together Peter Pickkers links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 443 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1 Journal of Clinical Investigation ·Janesh Pillay, Vera Kamp, Els van Hoffen, Tjaakje Visser, Tamar Tak, Jan‐Willem J. Lammers, Laurien H. Ulfman, Luke P. H. Leenen, Peter Pickkers, Leo Koenderman Hit paper breakdown →	2011	639
2	A Unified Theory of Sepsis-Induced Acute Kidney Injury Shock ·Hernando Gómez, Can İnce, Daniel De Backer, Peter Pickkers, Didier Payen, John R. Hotchkiss, John A. Kellum Hit paper breakdown →	2013	567
3	Inflammation in AKI Journal of the American Society of Nephrology ·Hamid Rabb, Matthew D. Griffin, Dianne B. McKay, Sundararaman Swaminathan, Peter Pickkers, Mitchell H. Rosner, John A. Kellum, Claudio Ronco Hit paper breakdown →	2015	444
4	Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis Nature Immunology ·Shih‐Chin Cheng, Brendon P. Scicluna, Rob J.W. Arts, Mark S. Gresnigt, Ekta Lachmandas, Evangelos J. Giamarellos‐Bourboulis, Matthijs Kox, Ganesh R. Manjeri, Jori A. Wagenaars, Olaf L. Cremer, Jenneke Leentjens, Anne Jan van der Meer, Frank L. van de Veerdonk, Marc J. M. Bonten, Marcus J. Schultz, Peter H.G.M. Willems, Peter Pickkers, Leo A. B. Joosten, Tom van der Poll, Mihai G. Netea Hit paper breakdown →	2016	438
5	Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS Blood ·Erwin Kemna, Peter Pickkers, Elizabeta Nemeth, Hans van der Hoeven, Dorine W. Swinkels	2005	413
6	Obesity in the critically ill: a narrative review Intensive Care Medicine ·Miet Schetz, Audrey De Jong, Adam M. Deane, Wilfried Druml, Pleun Hemelaar, Paolo Pelosi, Peter Pickkers, Annika Reintam Blaser, Jason A. Roberts, Yasser Sakr, Samir Jaber Hit paper breakdown →	2019	324
7	Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for intensive care patients: observational multicentre study BMJ ·Mark van den Boogaard, Peter Pickkers, Arjen J. C. Slooter, Michaël Kuiper, Peter E. Spronk, P. H. J. v. d. Voort, Johannes G. van der Hoeven, Rogier Donders, Theo van Achterberg, Lisette Schoonhoven	2012	307
8	Acute kidney injury in the critically ill: an updated review on pathophysiology and management Intensive Care Medicine ·Peter Pickkers, Michaël Darmon, Eric A. J. Hoste, Michael Joannidis, Matthieu Legrand, Marlies Ostermann, John R. Prowle, Antoine Schneider, Miet Schetz Hit paper breakdown →	2021	281
9	Delirium in critically ill patients Critical Care Medicine ·Mark van den Boogaard, Lisette Schoonhoven, Andrea W.M. Evers, Johannes G. van der Hoeven, Theo van Achterberg, Peter Pickkers	2011	275
10	Cytokine Levels in Critically Ill Patients With COVID-19 and Other Conditions JAMA ·Matthijs Kox, Nicole Waalders, Emma J. Kooistra, Jelle Gerretsen, Peter Pickkers	2020	208
11	Sepsis-Induced Immunosuppression Annual Review of Physiology ·Lisa K. Torres, Peter Pickkers, Tom van der Poll Hit paper breakdown →	2021	200
12	Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia Journal of Leukocyte Biology ·Janesh Pillay, Bart Ramakers, Vera Kamp, Adèle Lo Tam Loi, Siu W. Lam, Falco Hietbrink, Luke P. H. Leenen, Anton T. J. Tool, Peter Pickkers, Leo Koenderman	2010	195
13	A guide to immunotherapy for COVID-19 Nature Medicine ·Frank L. van de Veerdonk, Evangelos J. Giamarellos‐Bourboulis, Peter Pickkers, Lennie Derde, Helen L. Leavis, Reinout van Crevel, Job J. Engel, W. Joost Wiersinga, Alexander P. J. Vlaar, Manu Shankar‐Hari, Tom van der Poll, Marc J. M. Bonten, Derek Angus, J.W.M. van der Meer, Mihai G. Netea Hit paper breakdown →	2022	191
14	Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans Proceedings of the National Academy of Sciences ·Matthijs Kox, Lucas T. van Eijk, Jelle Zwaag, Joanne van den Wildenberg, Fred C.G.J. Sweep, Johannes G. van der Hoeven, Peter Pickkers	2014	187
15	Reversal of Immunoparalysis in Humans In Vivo : A Double-Blind, Placebo-controlled, Randomized Pilot Study American Journal of Respiratory and Critical Care Medicine ·Jenneke Leentjens, Matthijs Kox, Rebecca M. Koch, Frank Preijers, Leo A. B. Joosten, Johannes G. van der Hoeven, Mihai G. Netea, Peter Pickkers	2012	185
16	BCG Vaccination Enhances the Immunogenicity of Subsequent Influenza Vaccination in Healthy Volunteers: A Randomized, Placebo-Controlled Pilot Study The Journal of Infectious Diseases ·Jenneke Leentjens, Matthijs Kox, Robin Stokman, Jelle Gerretsen, Dimitri A. Diavatopoulos, Reinout van Crevel, Guus F. Rimmelzwaan, Peter Pickkers, Mihai G. Netea	2015	184
17	Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation. Time for a Paradigm Change? American Journal of Respiratory and Critical Care Medicine ·Jenneke Leentjens, Matthijs Kox, Johannes G. van der Hoeven, Mihai G. Netea, Peter Pickkers	2013	178
18	Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series BMC Infectious Diseases ·Corine Delsing, Mark S. Gresnigt, Jenneke Leentjens, Frank Preijers, Florence Allantaz Frager, Matthijs Kox, Guillaume Monneret, Fabienne Venet, Chantal P. Bleeker‐Rovers, Frank L. van de Veerdonk, Peter Pickkers, Alexandre Pachot, Bart Jan Kullberg, Mihai G. Netea	2014	177
19	Enteroendocrine L Cells Sense LPS after Gut Barrier Injury to Enhance GLP-1 Secretion Cell Reports ·L Lebrun, Kaatje Lenaerts, Dorien Kiers, Jean-Paul Paı̈s de Barros, Naïg Le Guern, Jiří Plesnik, Charles Thomas, Thibaut Bourgeois, Cornelis H.C. Dejong, Matthijs Kox, Inca H. Hundscheid, Naim Akhtar Khan, Stéphane Mandard, Valérie Deckert, Peter Pickkers, Daniel J. Drucker, Laurent Lagrost, Jacques Grober	2017	174
20	Incidence and short-term consequences of delirium in critically ill patients: A prospective observational cohort study International Journal of Nursing Studies ·Mark van den Boogaard, Lisette Schoonhoven, Johannes G. van der Hoeven, Theo van Achterberg, Peter Pickkers	2011	171

About Peter Pickkers

Peter Pickkers is a scholar working on Epidemiology, Immunology, Critical Care and Intensive Care Medicine, Surgery and Molecular Biology, having authored 443 papers that have together received 18.8k indexed citations. Recurring topics across this work include Sepsis Diagnosis and Treatment (118 papers), Immune Response and Inflammation (72 papers), Intensive Care Unit Cognitive Disorders (63 papers), Anesthesia and Sedative Agents (33 papers), Acute Kidney Injury Research (33 papers), Anesthesia and Neurotoxicity Research (29 papers), Respiratory Support and Mechanisms (28 papers) and Cardiac Arrest and Resuscitation (26 papers). The work is most often cited by research in Critical Care and Intensive Care Medicine (3.7k citations), Nephrology (2.3k citations), Anesthesiology and Pain Medicine (1.4k citations), Developmental Neuroscience (1.0k citations) and Immunology (4.2k citations). Peter Pickkers has collaborated with scholars based in Netherlands, United States and Germany. Frequent co-authors include Matthijs Kox, Johannes G. van der Hoeven, Mihai G. Netea, Mark van den Boogaard, Lisette Schoonhoven, Theo van Achterberg, Leo Koenderman, Paul Smits, Jenneke Leentjens and Jelle Gerretsen. Their work appears in journals such as Critical Care, Shock, Intensive Care Medicine, Critical Care Medicine and Journal of Critical Care.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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