Tina Ritschel

1.6k citations

32 papers · 1.1k indexed · h-index 20

Computational Theory and Mathematics top 2%
- Computational Drug Discovery Methods 6
Infectious Diseases top 10%
Molecular Biology
- RNA and protein synthesis mechanisms 10
- Chemical Synthesis and Analysis 4
- RNA modifications and cancer 4
Pharmacology top 10%
Epidemiology
- Respiratory viral infections research 3
Genetics
- Bacterial Genetics and Biotechnology 4
Radiology, Nuclear Medicine and Imaging
- Monoclonal and Polyclonal Antibodies Research 4
Materials Chemistry
- Enzyme Structure and Function 4

Co-authors: Frans G. M. Rüssel G. Klebe Ross McGuire Tom J.J. Schirris Jan Smeıtınk Nicolas Foloppe J. Kelder Valère Lounnas
Cited by: Computational Theory and Mathematics Infectious Diseases Molecular Biology
Journals: Proceedings of the National Academy of Sciences (1 paper)Angewandte Chemie International Edition (2 papers)Nature Communications (2 papers)
Partner nations: Netherlands Germany United States

In The Last Decade

Tina Ritschel

31 papers receiving 1.1k citations

Peers

Countries citing papers authored by Tina Ritschel

Since Specialization

Citations

This map shows the geographic impact of Tina Ritschel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tina Ritschel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tina Ritschel more than expected).

Fields of papers citing papers by Tina Ritschel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tina Ritschel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tina Ritschel. The network helps show where Tina Ritschel may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Tina Ritschel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tina Ritschel Line = papers co-authored together Tina Ritschel links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer Nature Communications ·Mark J. G. Bakkers,Tina Ritschel,Machteld M. Tiemessen,Jacobus Dijkman,Angelo A. Zuffianò,Xiaodi Yu,Daan van Overveld,Lam Le,Richard Voorzaat,Marlies M. van Haaren,Martijn de Man,Sem Tamara,Leslie van der Fits,Roland Zahn,Jarek Juraszek,Johannes P. M. Langedijk	2024	13
2	RSV A2-Based Prefusion F Vaccine Candidates Induce RSV A and RSV B Cross Binding and Neutralizing Antibodies and Provide Protection against RSV A and RSV B Challenge in Preclinical Models Vaccines ·Freek Cox,Eiríkur Saeland,Anne Thoma,Ward van den Hoogen,Lisanne Tettero,Joke Drijver,Cornelis Vaneman,Yolinda van Polanen,Tina Ritschel,Arangassery Rosemary Bastian,Benoît Callendret,Roland Zahn,Leslie van der Fits	2023	6
3	Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions Proceedings of the National Academy of Sciences ·Fin Milder,Mandy Jongeneelen,Tina Ritschel,Pascale Bouchier,Ilona J. M. Bisschop,Martijn de Man,Daniel Veldman,Lam Le,Baerbel Kaufmann,Mark J. G. Bakkers,Jarek Juraszek,Boerries Brandenburg,Johannes P. M. Langedijk	2022	25
4	Stabilizing the closed SARS-CoV-2 spike trimer Nature Communications ·Jarek Juraszek,Lucy Rutten,Sven Blokland,Pascale Bouchier,Richard Voorzaat,Tina Ritschel,Mark J. G. Bakkers,Ludovic Renault,Johannes P. M. Langedijk	2021	111
5	Drug Discovery and Repurposing Inhibits a Major Gut Pathogen-Derived Oncogenic Toxin Frontiers in Cellular and Infection Microbiology ·Paul Metz,Martijn J. H. Tjan,Shaoguang Wu,Mehrosh Pervaiz,Susanne M.A. Hermans,Aishwarya Shettigar,Cynthia L. Sears,Tina Ritschel,Bas E. Dutilh,Annemarie Boleij	2019	13
6	Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies PLoS Pathogens ·Harrison G. Jones,Tina Ritschel,Gabriel Pascual,Just P. J. Brakenhoff,Elissa Keogh,Polina Furmanova-Hollenstein,Ellen Lanckacker,Jehangir S. Wadia,Morgan S. A. Gilman,R. Anthony Williamson,Dirk Roymans,Angélique B. van ’t Wout,Johannes P. M. Langedijk,Jason S. McLellan	2018	54
7	Molecular interaction fingerprint approaches for GPCR drug discovery Current Opinion in Pharmacology ·Márton Vass,Albert J. Kooistra,Tina Ritschel,Rob Leurs,Iwan J. P. de Esch,Chris de Graaf	2016	36
8	Mitochondrial ADP/ATP exchange inhibition: a novel off-target mechanism underlying ibipinabant-induced myotoxicity Scientific Reports ·Tom J.J. Schirris,Tina Ritschel,G. Herma Renkema,Peter H.G.M. Willems,Jan Smeıtınk,Frans G. M. Rüssel	2015	17
9	Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition Cell Metabolism ·Tom J.J. Schirris,G. Herma Renkema,Tina Ritschel,Nicol C. Voermans,Albert Bilos,Baziel G.M. van Engelen,Ulrich Brandt,Werner J.H. Koopman,Julien Beyrath,Richard J. Rodenburg,Peter H.G.M. Willems,Jan Smeıtınk,Frans G. M. Rüssel	2015	169
10	Snooker Structure-Based Pharmacophore Model Explains Differences in Agonist and Blocker Binding to Bitter Receptor hTAS2R39 PLoS ONE ·Wibke S. U. Roland,Marijn P. A. Sanders,Leo van Buren,Robin J. Gouka,Harry Gruppen,Jean‐Paul Vincken,Tina Ritschel	2015	13
11	KRIPO – a structure-based pharmacophores approach explains polypharmacological effects Journal of Cheminformatics ·Tina Ritschel,Tom J.J. Schirris,Frans G. M. Rüssel	2014	7
12	Influence of azide incorporation on binding affinity by small papain inhibitors Bioorganic & Medicinal Chemistry ·Angelique E. M. Wammes,Tom Hendriks,Helene I. V. Amatdjais‐Groenen,Marloes A. Wijdeven,Jan C. M. van Hest,Floris L. van Delft,Tina Ritschel,Floris P. J. T. Rutjes	2014	0
13	High-affinity inhibitors ofZymomonas mobilistRNA–guanine transglycosylase through convergent optimization Acta Crystallographica Section D Biological Crystallography ·Luzi Jakob Barandun,F. Immekus,Philipp Köhler,Tina Ritschel,A. Heine,Pierfrancesco Orlando,G. Klebe,François Diederich	2013	10
14	CURRENT PROGRESS IN STRUCTURE-BASED RATIONAL DRUG DESIGN MARKS A NEW MINDSET IN DRUG DISCOVERY Computational and Structural Biotechnology Journal ·Valère Lounnas,Tina Ritschel,J. Kelder,Ross McGuire,Robert P. Bywater,Nicolas Foloppe	2013	149
15	From lin‐Benzoguanines to lin‐Benzohypoxanthines as Ligands for Zymomonas mobilis tRNA–Guanine Transglycosylase: Replacement of Protein–Ligand Hydrogen Bonding by Importing Water Clusters Chemistry - A European Journal ·Luzi Jakob Barandun,F. Immekus,Philipp Köhler,Sandro Tonazzi,Björn Wagner,Severin Wendelspiess,Tina Ritschel,A. Heine,Manfred Kansy,G. Klebe,François Diederich	2012	19
16	How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA‐Guanine Transglycosylase ChemMedChem ·Tina Ritschel,Philipp Köhler,Gerd Neudert,A. Heine,François Diederich,G. Klebe	2009	25
17	Crystal Structure Analysis and in Silico pK_a Calculations Suggest Strong pK_a Shifts of Ligands as Driving Force for High‐Affinity Binding to TGT ChemBioChem ·Tina Ritschel,S. Hoertner,A. Heine,François Diederich,G. Klebe	2009	20
18	An Integrative Approach Combining Noncovalent Mass Spectrometry, Enzyme Kinetics and X-ray Crystallography to Decipher Tgt Protein-Protein and Protein-RNA Interaction Journal of Molecular Biology ·Tina Ritschel,Cédric Atmanène,Klaus Reuter,Alain Van Dorsselaer,Sarah Cianférani,G. Klebe	2009	36
19	High‐Affinity Inhibitors of tRNA‐Guanine Transglycosylase Replacing the Function of a Structural Water Cluster Chemistry - A European Journal ·Philipp Köhler,Tina Ritschel,W. Bernd Schweizer,G. Klebe,François Diederich	2009	27
20	Potent Inhibitors of tRNA‐Guanine Transglycosylase, an Enzyme Linked to the Pathogenicity of the Shigella Bacterium: Charge‐Assisted Hydrogen Bonding Angewandte Chemie International Edition ·Simone R. Hörtner,Tina Ritschel,B. Stengl,Christian Krämer,W. Bernd Schweizer,Björn Wagner,Manfred Kansy,G. Klebe,François Diederich	2007	42

About Tina Ritschel

Tina Ritschel is a scholar working on Computational Theory and Mathematics, Infectious Diseases and Molecular Biology, having authored 32 papers that have together received 1.1k indexed citations. Recurring topics across this work include RNA and protein synthesis mechanisms (10 papers), Computational Drug Discovery Methods (6 papers), Chemical Synthesis and Analysis (4 papers), RNA modifications and cancer (4 papers), Bacterial Genetics and Biotechnology (4 papers), Monoclonal and Polyclonal Antibodies Research (4 papers), Enzyme Structure and Function (4 papers) and Respiratory viral infections research (3 papers). The work is most often cited by research in Computational Theory and Mathematics (223 citations), Infectious Diseases (183 citations) and Molecular Biology (627 citations). Tina Ritschel has collaborated with scholars based in Netherlands, Germany and United States. Frequent co-authors include Frans G. M. Rüssel, G. Klebe, Ross McGuire, Tom J.J. Schirris, Jan Smeıtınk, Nicolas Foloppe, J. Kelder, Valère Lounnas, Robert P. Bywater and François Diederich. Their work appears in journals such as Proceedings of the National Academy of Sciences, Angewandte Chemie International Edition and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact