Rob Leurs

24.2k total citations · 2 hit papers
443 papers, 19.1k citations indexed

About

Rob Leurs is a scholar working on Molecular Biology, Immunology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Rob Leurs has authored 443 papers receiving a total of 19.1k indexed citations (citations by other indexed papers that have themselves been cited), including 307 papers in Molecular Biology, 235 papers in Immunology and 79 papers in Cellular and Molecular Neuroscience. Recurrent topics in Rob Leurs's work include Receptor Mechanisms and Signaling (246 papers), Mast cells and histamine (196 papers) and Chemical Synthesis and Analysis (57 papers). Rob Leurs is often cited by papers focused on Receptor Mechanisms and Signaling (246 papers), Mast cells and histamine (196 papers) and Chemical Synthesis and Analysis (57 papers). Rob Leurs collaborates with scholars based in Netherlands, United States and United Kingdom. Rob Leurs's co-authors include Martine J. Smit, Iwan J. P. de Esch, Henk Timmerman, Remko A. Bakker, H. Timmerman, Henry F. Vischer, Chris de Graaf, Maikel Wijtmans, Albert J. Kooistra and Herman D. Lim and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Nucleic Acids Research.

In The Last Decade

Rob Leurs

437 papers receiving 18.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.

1993 530 citations Rob Leurs et al. profile →
International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors

2015 414 citations Rob Leurs et al. profile →

Peers

Countries citing papers authored by Rob Leurs

Since Specialization

Citations

This map shows the geographic impact of Rob Leurs's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rob Leurs with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rob Leurs more than expected).

Fields of papers citing papers by Rob Leurs

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rob Leurs. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rob Leurs. The network helps show where Rob Leurs may publish in the future.

Co-authorship network of co-authors of Rob Leurs

This figure shows the co-authorship network connecting the top 25 collaborators of Rob Leurs. A scholar is included among the top collaborators of Rob Leurs based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rob Leurs. Rob Leurs is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Design and synthesis of photoswitchable desloratadine ligands for histamine H ₁ receptor photopharmacology 2025 ·RSC Medicinal Chemistry ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Oscar P. J. van Linden, Iwan J. P. de Esch, Henry F. Vischer, Maikel Wijtmans, Rob Leurs	0
2	Inhibition of constitutive activity of the atypical chemokine receptor 3 by the small-molecule inverse agonist VUF16840 2025 ·Molecular Pharmacology ·Reggie Bosma, (unknown), (unknown), (unknown), (unknown), Max Meyrath, (unknown), (unknown), Susanne M. A. van der Pol, Iwan J. P. de Esch, Martyna Szpakowska, Maikel Wijtmans, Andy Chevigné, Henry F. Vischer, Rob Leurs	1
3	Synthesis and Pharmacological Characterization of New Photocaged Agonists for Histamine H3 and H4 Receptors 2024 ·Pharmaceuticals ·Yang Zheng, (unknown), Maikel Wijtmans, Henry F. Vischer, Rob Leurs	3
4	Structural basis of ligand recognition and design of antihistamines targeting histamine H4 receptor 2024 ·Nature Communications ·Ruixue Xia, Shuang Shi, Zhenmei Xu, Henry F. Vischer, Albert D. Windhorst, Qian Yu, (unknown), (unknown), Kai Chen, Anqi Zhang, Changyou Guo, Rob Leurs, Yuanzheng He	7
5	Multiplex Detection of Fluorescent Chemokine Binding to CXC Chemokine Receptors by NanoBRET 2024 ·International Journal of Molecular Sciences ·(unknown), (unknown), Reggie Bosma, Henry F. Vischer, Rob Leurs	2
6	Structural Optimization of BIPPO Analogs as Potent Antimalarials 2023 ·Molecules ·Yang Zheng, An Matheeussen, Louis Maes, Guy Caljon, (unknown), Rob Leurs	2
7	Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3) 2023 ·ACS Medicinal Chemistry Letters ·(unknown), (unknown), (unknown), Marta Arimont, Meritxell Canals, (unknown), Chris de Graaf, Laura E. Kilpatrick, Rob Leurs, Barrie Kellam, Stephen J. Hill, Stephen J. Briddon, Michael J. Stocks	3
8	A NanoBRET-Based H3R Conformational Biosensor to Study Real-Time H3 Receptor Pharmacology in Cell Membranes and Living Cells 2022 ·International Journal of Molecular Sciences ·(unknown), (unknown), Henry F. Vischer, Rob Leurs	4
9	3-nitroimidazo[1,2-b]pyridazine as a novel scaffold for antiparasitics with sub-nanomolar anti-Giardia lamblia activity 2022 ·International Journal for Parasitology Drugs and Drug Resistance ·Yang Zheng, Joachim Müller, Stefan Kunz, Marco Siderius, Louis Maes, Guy Caljon, Norbert Müller, Andrew Hemphill, Geert Jan Sterk, Rob Leurs	9
10	Analysis of Missense Variants in the Human Histamine Receptor Family Reveals Increased Constitutive Activity of E4106.30×30K Variant in the Histamine H1 Receptor 2021 ·International Journal of Molecular Sciences ·(unknown), (unknown), Barbara Zarzycka, Henry F. Vischer, Rob Leurs	5
11	Identification of TSPAN4 as Novel Histamine H4 Receptor Interactor 2021 ·Biomolecules ·(unknown), (unknown), Marco Siderius, Rob Leurs, Henry F. Vischer	7
12	A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light 2019 ·Beilstein Journal of Organic Chemistry ·Xavier Gómez‐Santacana, (unknown), Tamara A. M. Mocking, (unknown), Shan‐Liang Sun, (unknown), Iwan J. P. de Esch, Henry F. Vischer, Maikel Wijtmans, Rob Leurs	14
13	Design, synthesis, andin vitroandin vivocharacterization of 1-{4-[4-(substituted)piperazin-1-yl]butyl}guanidines and their piperidine analogues as histamine H₃receptor antagonists 2019 ·MedChemComm ·(unknown), Anna Stasiak, Tadeusz Karcz, (unknown), W. A. Fogel, Katarzyna Kieć‐Kononowicz, Rob Leurs, Krzysztof Walczyński	5
14	Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells 2018 ·Scientific Reports ·Leigh A. Stoddart, Andrea J. Vernall, (unknown), Reggie Bosma, Albert J. Kooistra, Chris de Graaf, Henry F. Vischer, Rob Leurs, Stephen J. Briddon, Barrie Kellam, Stephen J. Hill	51
15	The third generation of antihistamines: Assessment of Histamine H1/H4 Receptor Antagonists in a Murine Model of Allergic Conjunctivitis 2014 ·Investigative Ophthalmology & Visual Science ·(unknown), (unknown), (unknown), Jac C.H.M. Wijkmans, (unknown), (unknown), Rogier A. Smits, Iwan J. P. de Esch, Rob Leurs	1
16	Ayatollah Khomeini: The changing face of Islam 2012 ·SHILAP Revista de lepidopterología ·Rob Leurs	1
17	Crystal Structure-Based Virtual Screening for Fragment-like Ligands of the Human Histamine H ₁ Receptor 2011 ·Journal of Medicinal Chemistry ·Chris de Graaf, Albert J. Kooistra, Henry F. Vischer, Vsevolod Katritch, (unknown), Mitsunori Shiroishi, So Iwata, Tatsuro Shimamura, Raymond C. Stevens, Iwan J. P. de Esch, Rob Leurs	162
18	The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice 2010 ·Journal of Clinical Investigation ·Gerold Bongers, David Maussang, Luciana R. Muniz, Vanessa M. Noriega, Alberto Fraile‐Ramos, Nick Barker, Federica Marchesi, Nanthakumar Thirunarayanan, Henry F. Vischer, Lihui Qin, Lloyd Mayer, Noam Harpaz, Rob Leurs, Gláucia C. Furtado, Hans Clevers, Domenico Tortorella, Martine J. Smit, Sérgio A. Lira	89
19	The Human Cytomegalovirus–Encoded Chemokine Receptor US28 Promotes Angiogenesis and Tumor Formation via Cyclooxygenase-2 2009 ·Cancer Research ·David Maussang, Ellen Langemeijer, Carlos P. Fitzsimons, Marijke Stigter‐van Walsum, Remco Dijkman, (unknown), Erik Slinger, Andreas Schreiber, Detlef Michel, Cornelis P. Tensen, Guus A.M.S. van Dongen, Rob Leurs, Martine J. Smit	128
20	CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C–dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase 2003 ·Blood ·Martine J. Smit, Pauline Verdijk, (unknown), Marjon Navis, Paul J. Hensbergen, Rob Leurs, Cornelis P. Tensen	139

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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