Steven E. Shoelson

43.8k total citations · 14 hit papers
173 papers, 35.9k citations indexed

About

Steven E. Shoelson is a scholar working on Molecular Biology, Immunology and Epidemiology. According to data from OpenAlex, Steven E. Shoelson has authored 173 papers receiving a total of 35.9k indexed citations (citations by other indexed papers that have themselves been cited), including 116 papers in Molecular Biology, 35 papers in Immunology and 33 papers in Epidemiology. Recurrent topics in Steven E. Shoelson's work include Protein Kinase Regulation and GTPase Signaling (44 papers), Adipokines, Inflammation, and Metabolic Diseases (29 papers) and Metabolism, Diabetes, and Cancer (24 papers). Steven E. Shoelson is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (44 papers), Adipokines, Inflammation, and Metabolic Diseases (29 papers) and Metabolism, Diabetes, and Cancer (24 papers). Steven E. Shoelson collaborates with scholars based in United States, Canada and South Korea. Steven E. Shoelson's co-authors include Marc Y. Donath, Jongsoon Lee, Minsheng Yuan, Laura Herrero, Afia Naaz, Lone Hansen, Michael J. Eck, Diane Mathis, Morris F. White and Dongsheng Cai and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Steven E. Shoelson

171 papers receiving 35.2k citations

Hit Papers

Inflammation and insulin resistance 1994 2026 2004 2015 2006 2011 1994 2005 2009 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Inflammation and insulin resistance
    2006 3.7k citations Steven E. Shoelson Journal of Clinical Investigation profile →
  2. Type 2 diabetes as an inflammatory disease
    2011 2.8k citations Steven E. Shoelson et al. profile →
  3. Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation
    1994 1.9k citations Steven E. Shoelson et al. Biochemistry profile →
  4. Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
    2005 1.8k citations Dongsheng Cai, Minsheng Yuan et al. Nature Medicine profile →
  5. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
    2009 1.7k citations Jongsoon Lee, Christophe Benoıst et al. Nature Medicine profile →
  6. Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ
    2001 1.5k citations Minsheng Yuan, Jongsoon Lee et al. profile →
  7. Obesity, Inflammation, and Insulin Resistance
    2007 1.4k citations Steven E. Shoelson et al. profile →
  8. IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice
    2004 1.1k citations Dongsheng Cai, J. Daniel Frantz et al. Cell profile →
  9. PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
    2012 915 citations Jongsoon Lee, Steven E. Shoelson et al. profile →
  10. Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance
    1998 835 citations J. Daniel Frantz, Steven E. Shoelson et al. profile →
  11. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.
    1994 799 citations Zhou Songyang, Steven E. Shoelson et al. Molecular and Cellular Biology profile →
  12. Crystal Structure of the Tyrosine Phosphatase SHP-2
    1998 786 citations Peter Hof, Scott Pluskey et al. Cell profile →
  13. SOCS-1 and SOCS-3 Block Insulin Signaling by Ubiquitin-mediated Degradation of IRS1 and IRS2
    2002 721 citations Minsheng Yuan, Steven E. Shoelson et al. Journal of Biological Chemistry profile →
  14. Prevention of fat-induced insulin resistance by salicylate
    2001 574 citations Jason K. Kim, Yun Joong Kim et al. Journal of Clinical Investigation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Steven E. Shoelson United States 79 17.7k 9.3k 8.1k 7.9k 4.5k 173 35.9k
Alan R. Saltiel United States 93 25.3k 1.4× 9.4k 1.0× 11.2k 1.4× 6.4k 0.8× 4.9k 1.1× 280 45.5k
Walter Wahli Switzerland 96 28.5k 1.6× 6.2k 0.7× 11.9k 1.5× 3.2k 0.4× 3.2k 0.7× 325 42.0k
Masato Kasuga Japan 96 18.3k 1.0× 4.0k 0.4× 6.8k 0.8× 3.3k 0.4× 5.5k 1.2× 555 35.0k
Peter Tontonoz United States 95 27.4k 1.5× 7.8k 0.8× 10.6k 1.3× 7.2k 0.9× 3.3k 0.7× 228 45.0k
Ryozo Nagai Japan 104 18.1k 1.0× 8.8k 0.9× 8.1k 1.0× 4.7k 0.6× 3.5k 0.8× 859 45.6k
David A. Brenner United States 132 20.1k 1.1× 26.8k 2.9× 4.7k 0.6× 7.1k 0.9× 4.3k 1.0× 517 59.5k
Mitchell A. Lazar United States 125 30.0k 1.7× 12.7k 1.4× 16.7k 2.1× 4.6k 0.6× 6.6k 1.5× 325 56.1k
Peter P. Nawroth Germany 95 9.8k 0.6× 4.0k 0.4× 6.4k 0.8× 6.5k 0.8× 5.1k 1.1× 494 36.3k
Bin Gao United States 103 11.2k 0.6× 14.8k 1.6× 2.6k 0.3× 7.4k 0.9× 3.9k 0.9× 483 36.3k
Eric Verdin United States 115 24.9k 1.4× 8.1k 0.9× 11.0k 1.4× 5.8k 0.7× 1.7k 0.4× 279 47.7k

Countries citing papers authored by Steven E. Shoelson

Since Specialization
Citations

This map shows the geographic impact of Steven E. Shoelson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven E. Shoelson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven E. Shoelson more than expected).

Fields of papers citing papers by Steven E. Shoelson

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven E. Shoelson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven E. Shoelson. The network helps show where Steven E. Shoelson may publish in the future.

Co-authorship network of co-authors of Steven E. Shoelson

This figure shows the co-authorship network connecting the top 25 collaborators of Steven E. Shoelson. A scholar is included among the top collaborators of Steven E. Shoelson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven E. Shoelson. Steven E. Shoelson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Diepen, Janna A. van, Bruno Guigas, Rinke Stienstra, et al.. (2011). Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice. Journal of Lipid Research. 52(5). 942–950. 20 indexed citations
2.
Kuo, Alex, Peggie Cheung, Jakub Abramson, et al.. (2008). Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity. Proceedings of the National Academy of Sciences. 105(41). 15878–15883. 142 indexed citations
3.
Nishi, Masahiro, Eric D. Werner, Byung‐Chul Oh, et al.. (2005). Kinase Activation through Dimerization by Human SH2-B. Molecular and Cellular Biology. 25(7). 2607–2621. 49 indexed citations
4.
Cai, Dongsheng, Minsheng Yuan, Peter A. Meléndez, et al.. (2005). Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB. Nature Medicine. 11(2). 183–190. 1830 indexed citations breakdown →
5.
Hundal, Ripudaman S., Kitt Falk Petersen, Adam B. Mayerson, et al.. (2002). Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. Journal of Clinical Investigation. 109(10). 1321–1326. 35 indexed citations
6.
Hundal, Ripudaman S., Kitt Falk Petersen, Adam B. Mayerson, et al.. (2002). Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. Journal of Clinical Investigation. 109(10). 1321–1326. 439 indexed citations
7.
Chi, Young‐In, J.D. Frantz, Bermseok Oh, Lone Hansen, & Steven E. Shoelson. (2002). DIABETES MUTATIONS DELINEATE AN ATYPICAL POU DOMAIN IN HNF1A.. Molecules and Cells. 10. 1 indexed citations
8.
Kim, Jason K., Yun Joong Kim, Jonathan J. Fillmore, et al.. (2001). Prevention of fat-induced insulin resistance by salicylate. Journal of Clinical Investigation. 108(3). 437–446. 574 indexed citations breakdown →
9.
Kim, Jason K., Steven E. Shoelson, & Gerald I. Shulman. (2001). The effect of salicylates on insulin sensitivity. Journal of Clinical Investigation. 108(11). 1724–1724. 1 indexed citations
10.
Lindholm, Cecilia, J. Daniel Frantz, Steven E. Shoelson, & Michael Welsh. (2000). Shf, a Shb-like Adapter Protein, Is Involved in PDGF-α-Receptor Regulation of Apoptosis. Biochemical and Biophysical Research Communications. 278(3). 537–543. 26 indexed citations
11.
Dhe‐Paganon, Sirano, Ron Shigeta, Young‐In Chi, Michael Ristow, & Steven E. Shoelson. (2000). Crystal Structure of Human Frataxin. Journal of Biological Chemistry. 275(40). 30753–30756. 181 indexed citations
12.
Hof, Peter, Scott Pluskey, Sirano Dhe‐Paganon, Michael J. Eck, & Steven E. Shoelson. (1998). Crystal Structure of the Tyrosine Phosphatase SHP-2. Cell. 92(4). 441–450. 786 indexed citations breakdown →
13.
Giorgetti‐Peraldi, Sophie, Elizabeth A. Ottinger, G. Wolf, et al.. (1997). Cellular Effects of Phosphotyrosine-Binding Domain Inhibitors on Insulin Receptor Signaling and Trafficking. Molecular and Cellular Biology. 17(3). 1180–1188. 30 indexed citations
14.
Shoelson, Steven E.. (1997). SH2 and PTB domain interactions in tyrosine kinase signal transduction. Current Opinion in Chemical Biology. 1(2). 227–234. 74 indexed citations
15.
Ravichandran, Kodi S., Ulrike Lorenz, Steven E. Shoelson, & Steven J. Burakoff. (1995). Interaction of Shc with Grb2 Regulates Association of Grb2 with mSOS. Molecular and Cellular Biology. 15(2). 593–600. 156 indexed citations
16.
Schneider, Hal E., Kartik Prasad, Steven E. Shoelson, & Christopher E. Rudd. (1995). CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells.. The Journal of Experimental Medicine. 181(1). 351–355. 143 indexed citations
17.
Fukazawa, Toru, Lesley A. Stolz, Gillian Payne, et al.. (1994). Physical and Functional Interactions between SH2 and SH3 Domains of the Src Family Protein Tyrosine Kinase p59 fyn . Molecular and Cellular Biology. 14(9). 6372–6385. 11 indexed citations
18.
Payne, Gillian, Lesley A. Stolz, Dehua Pei, et al.. (1994). The phosphopeptide-binding specificity of Src family SH2 domains. Chemistry & Biology. 1(2). 99–105. 30 indexed citations
19.
Chuang, Lee‐Ming, Martin G. Myers, Jonathan Backer, et al.. (1993). Insulin-Stimulated Oocyte Maturation Requires Insulin Receptor Substrate 1 and Interaction with the SH2 Domains of Phosphatidylinositol 3-Kinase. Molecular and Cellular Biology. 13(11). 6653–6660. 14 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Alan R. Saltiel Breakdown of academic impact, for papers by Walter Wahli Breakdown of academic impact, for papers by Masato Kasuga Breakdown of academic impact, for papers by Peter Tontonoz Breakdown of academic impact, for papers by Ryozo Nagai Breakdown of academic impact, for papers by David A. Brenner Breakdown of academic impact, for papers by Mitchell A. Lazar Breakdown of academic impact, for papers by Peter P. Nawroth Breakdown of academic impact, for papers by Bin Gao Breakdown of academic impact, for papers by Eric Verdin
Rankless by CCL
2026