Bruno Guigas

12.0k citations

117 papers · 9.0k indexed · 4 hit papers · h-index 42

Impact in

Endocrinology, Diabetes and Metabolism top 0.5%
- Diabetes Treatment and Management
- Diet, Metabolism, and Disease
Aging top 2%

Papers in

Physiology 43
- Adipose Tissue and Metabolism 31
- Diet and metabolism studies 15
Parasitology 10
- Parasites and Host Interactions 10

Co-authors: Benoı̂t Viollet Marc Foretz Luc Bertrand Fabrizio Andréelli Jocelyne Leclerc Dominique Détaille Michaël Pollak Louis Hue
Journals: Diabetes (7 papers)Frontiers in Immunology (6 papers)Journal of Biological Chemistry (4 papers)International Journal of Obesity (4 papers)Scientific Reports (3 papers)
Partner nations: Netherlands France Belgium

In The Last Decade

Bruno Guigas

113 papers receiving 8.9k citations

Hit Papers

align trajectories log scale

Metformin: update on mechanisms of action and repurposing potential 2023 · 360 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2023 Nature Reviews Endocrinology
2019 Nature Reviews Endocrinology
2014 Cell Metabolism
2011 Clinical Science

Peers

Countries citing papers authored by Bruno Guigas

Since Specialization

Citations

This map shows the geographic impact of Bruno Guigas's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruno Guigas with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruno Guigas more than expected).

Fields of papers citing papers by Bruno Guigas

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruno Guigas. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruno Guigas. The network helps show where Bruno Guigas may publish in the future.

Co-authors

The 25 scholars most cited alongside Bruno Guigas, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bruno Guigas Line = papers co-authored together Bruno Guigas links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The polyphenol-rich plant extract Totum-448 decreases hepatic steatosis and inflammation in diet-induced MASLD mice SHILAP Revista de lepidopterología ·Joost M. Lambooij, Vivien Chavanelle, Marie Vallier, Hendrik J.P. van der Zande, Yolanda F. Otero, Anuva Barman, Yuhan Yang, Massimo Pirondini, Thierry Maugard, Martin Giera, Sébastien Peltier, Arnaud Zaldumbide, Pascal Sirvent, Bruno Guigas	2025	0
2	Deleting ACC1 in platelets alters phospholipidome and reduces platelet activation and thrombosis in mice Blood Advances ·Xuanhui Chen, Ernst. Mecklenburg, J. M. Urbach, Alice Marino, Jérôme Ambroise, Martin Giera, Bruno Guigas, Audrey Ginion, C. Jason Wang, Marijke J. E. Kuijpers, Constance C. F. M. J. Baaten, Johan W. M. Heemskerk, Zoltán Nagy, Yotis A. Senis, Davide Brusa, Caroline Bouzin, Luc Bertrand, Christophe Beauloye, Sandrine Horman	2025	0
3	Timing Matters: Late, but Not Early, Exercise Training Ameliorates MASLD in Part by Modulating the Gut‐Liver Axis in Mice Journal of Pineal Research ·Patrice Gosselin, Zhixiong Ying, Sen Zhang, Elena Olgiati, Joost M. Lambooij, Edgar S. García Jiménez, Bruno Guigas, Quinten R. Ducarmon, Patrick C.N. Rensen, Milena Schönke	2024	6
4	S. mansoni -derived omega-1 prevents OVA-specific allergic airway inflammation via hampering of cDC2 migration PLoS Pathogens ·Thiago A. Patente, Edward Yadzinsky, Maaike R. Scheenstra, Arifa Ozir‐Fazalalikhan, Yunfeng Ma, Sjoerd Schetters, Daniel Beno, Karl Vergote, Anuva Barman, Ruud H. P. Wilbers, Estelle Segonds-Domart, Yolanda van Wijck, Christian Taube, Hamida Hammad, A. Schots, Bart Everts, Maria Yazdanbakhsh, Bruno Guigas, Cornelis H. Hokke, Hermelijn H. Smits	2024	3
5	AMPK activation induces RALDH+ tolerogenic dendritic cells by rewiring glucose and lipid metabolism The Journal of Cell Biology ·Eline C. Brombacher, Thiago A. Patente, Alwin J. van der Ham, A. A. Adefisoye, Anuva Barman, F.W. Verheijen, Esther A. Zaal, Arnoud H. de Ru, J. Deveseleer, Celia R. Berkers, Peter A. van Veelen, Bruno Guigas, Bart Everts	2024	5
6	Combined GIP receptor and GLP1 receptor agonism attenuates NAFLD in male APOE∗3-Leiden.CETP mice EBioMedicine ·Zhixiong Ying, DEMBINSKA Izabela, 和弘大串, V M Lariononv, Joost M. Lambooij, Bruno Guigas, Martin Giera, Jan Freark de Boer, Tamer Coşkun, Hongchang Qu, Yanan Wang, Mariëtte R. Boon, Patrick C.N. Rensen, Sander Kooijman	2023	14
7	A novel polyphenol-rich combination of 5 plant extracts prevents high-fat diet-induced body weight gain by regulating intestinal macronutrient absorption in mice Nutrition Research ·Vivien Chavanelle, Cédric Langhi, Koichiro SANO, Ida Saliny Hassan, Yolanda F. Otero, Massimo Pirondini, Thierry Maugard, Bruno Guigas, Martin Giera, Sébastien Peltier, Pascal Sirvent	2023	2
8	Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption Nutrients ·Cédric Langhi, Marie Vallier, Yolanda F. Otero, Wilhelm Hamacher, Massimo Pirondini, Hugo Groult, Seyed Medhi Nourani, Proceso Organizativo del Pueblo Rom de Colombia, Martin Giera, Bruno Guigas, Thierry Maugard, Benoît Chassaing, Sébastien Peltier, Jean‐Marie Bard, Quanjiang Li	2023	4
9	Dendritic cell–intrinsic LKB1-AMPK/SIK signaling controls metabolic homeostasis by limiting the hepatic Th17 response during obesity JCI Insight ·Hendrik J.P. van der Zande, Eline C. Brombacher, Joost M. Lambooij, Leonard R. Pelgrom, Anna Zawistowska‐Deniziak, Thiago A. Patente, Steves Paterne Nkoulou, Anuva Barman, Arifa Ozir‐Fazalalikhan, Maria Yazdanbakhsh, Bart Everts, Bruno Guigas	2023	11
10	FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis eLife ·Cong Liu, Milena Schönke, 黄钦全, Joost M. Lambooij, Hendrik J.P. van der Zande, Enchen Zhou, Maarten E. Tushuizen, Anne‐Christine Andréasson, Andrew Park, Stephanie Oldham, 姜淇远, Sergey Belyanchikov, Yasuhiro Ikeda, Kristina Wallenius, Xiaorong Peng, Bruno Guigas, Mariëtte R. Boon, Yanan Wang, Patrick C.N. Rensen	2023	46
11	Linking platelet lipidome and inflammatory response in septic patients Archives of Cardiovascular Diseases Supplements ·K. Peter, Mélanie Dechamps, L. Morhrmann, Christine Des Rosiers, Anik Forest, Bruno Guigas, Martin Giera, Jérôme Ambroise, Luc Bertrand, Christophe Beauloye, Sandrine Horman	2023	1
12	Metformin: update on mechanisms of action and repurposing potential Nature Reviews Endocrinology ·Marc Foretz, Bruno Guigas, Benoı̂t Viollet Hit paper breakdown →	2023	360
13	Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation EMBO Molecular Medicine ·Enchen Zhou, 和弘大串, Hiroyuki Nakashima, Rumei Li, Hendrik J.P. van der Zande, Cong Liu, Zhuang Li, Christoph Müller, Franz Bracher, Yassene Mohammed, Jan Freark de Boer, Folkert Kuipers, Bruno Guigas, Christopher K. Glass, Patrick C.N. Rensen, Martin Giera, Yanan Wang	2023	19
14	Schistosoma haematobium infection is associated with lower serum cholesterol levels and improved lipid profile in overweight/obese individuals PLoS neglected tropical diseases ·Jeannot Fréjus Zinsou, Jacqueline J. Janse, Gilles Brosseau, Jean Claude Dejon‐Agobé, Noemí García‐Tardón, Pytsje T. Hoekstra, Marguerite Massinga Loembé, Paul L. A. M. Corstjens, Govert J. van Dam, Martin Giera, Peter G. Kremsner, Maria Yazdanbakhsh, Ayôla Akim Adégnika, Bruno Guigas	2020	22
15	C-Myc plays a crucial role in chronic liver injury Journal of Viral Hepatitis ·李静睿, М. В. Патика, Bruno Guigas, O. A. Alduhov, Jessica Endig, Ulrika Bärdén, Silke Marhenke, Michael P. Manns, Arthur Vogel	2015	1
16	Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity (vol 10, e0127746, 2015) PLoS ONE ·Aprilianto E. Wiria, Firdaus Hamid, Linda J. Wammes, 貞丈一色, Olaf M. Dekkers, Xuehuan Ma, Maria Mardalena Martini Kaisar, Jaco J. Verweij, Bruno Guigas, F Partònò, Erliyani Sartono, Taniawati Supali, Maria Yazdanbakhsh, Johannes W. A. Smit	2015	1
17	CD 24 ^hi CD 27 ⁺ B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide Clinical & Experimental Allergy ·Luciën E. P. M. van der Vlugt, М.А. Волгин, Arifa Ozir‐Fazalalikhan, Montse Janssen Bonás, J. Takita, Lucja A. Labuda, Robert Schot, Bruno Guigas, Gertrude M. Möller, Pieter S. Hiemstra, Maria Yazdanbakhsh, Hermelijn H. Smits	2013	72
18	Impact of Metformin and Compound C on NIS Expression and Iodine Uptake In Vitro and In Vivo: A Role for CRE in AMPK Modulation of Thyroid Function Thyroid ·R Commission, Mariëtte R. Boon, Hetty C. M. Sips, Bruno Guigas, Patrick C.N. Rensen, Johannes W. A. Smit, Guido C. Hovens	2013	28
19	Du cancer au traitement du diabète : le suppresseur de tumeur LKB1 comme nouvelle cible pharmacologique médecine/sciences ·Marc Foretz, Bruno Guigas, Benoı̂t Viollet	2006	2
20	Régulation du métabolisme énergétique par l’AMPK : Une nouvelle voie thérapeutique pour le traitement des maladies métaboliques et cardiaques médecine/sciences ·Marc Foretz, Nellie Taleux, Bruno Guigas, Sandrine Horman, Christophe Beauloye, Fabrizio Andréelli, Luc Bertrand, Benoı̂t Viollet	2006	16

About Bruno Guigas

Bruno Guigas is a scholar working on Physiology, Parasitology, Endocrinology, Diabetes and Metabolism, Aging and Surgery, having authored 117 papers that have together received 9.0k indexed citations. Recurring topics across this work include Metabolism, Diabetes, and Cancer (42 papers), Pancreatic function and diabetes (36 papers), Adipose Tissue and Metabolism (31 papers), Diet and metabolism studies (15 papers), Adipokines, Inflammation, and Metabolic Diseases (13 papers), Parasites and Host Interactions (10 papers), Liver Disease Diagnosis and Treatment (10 papers) and Mitochondrial Function and Pathology (8 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (2.0k citations), Aging (155 citations), Physiology (2.1k citations), Molecular Biology (5.1k citations) and Geriatrics and Gerontology (212 citations). Bruno Guigas has collaborated with scholars based in Netherlands, France and Belgium. Frequent co-authors include Benoı̂t Viollet, Marc Foretz, Luc Bertrand, Fabrizio Andréelli, Jocelyne Leclerc, Dominique Détaille, Michaël Pollak, Louis Hue, Xavier Leverve and Éric Fontaine. Their work appears in journals such as Diabetes, Frontiers in Immunology, Journal of Biological Chemistry, International Journal of Obesity and Scientific Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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