Thomas Holcomb

3.8k total citations · 2 hit papers
26 papers, 2.4k citations indexed

About

Thomas Holcomb is a scholar working on Molecular Biology, Pulmonary and Respiratory Medicine and Clinical Biochemistry. According to data from OpenAlex, Thomas Holcomb has authored 26 papers receiving a total of 2.4k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Molecular Biology, 5 papers in Pulmonary and Respiratory Medicine and 4 papers in Clinical Biochemistry. Recurrent topics in Thomas Holcomb's work include Metabolism and Genetic Disorders (4 papers), Mitochondrial Function and Pathology (3 papers) and Hedgehog Signaling Pathway Studies (3 papers). Thomas Holcomb is often cited by papers focused on Metabolism and Genetic Disorders (4 papers), Mitochondrial Function and Pathology (3 papers) and Hedgehog Signaling Pathway Studies (3 papers). Thomas Holcomb collaborates with scholars based in United States, Austria and Japan. Thomas Holcomb's co-authors include Robert L. Yauch, Jeremy Stinson, Charles M. Rudin, Jennifer A. Low, Christine L. Hann, Frédéric J. de Sauvage, Stephen E. Gould, Christopher A. Callahan, Somasekar Seshagiri and Kanan Pujara and has published in prestigious journals such as Science, New England Journal of Medicine and PEDIATRICS.

In The Last Decade

Thomas Holcomb

26 papers receiving 2.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

2009 761 citations Charles M. Rudin, Christine L. Hann et al. New England Journal of Medicine profile →
Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

2009 670 citations Robert L. Yauch, Gerrit J.P. Dijkgraaf et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Thomas Holcomb United States	16	1.9k	587	320	313	287	26	2.4k
Kurt Grünewald Austria	18	902 0.5×	669 1.1×	282 0.9×	163 0.5×	203 0.7×	29	2.2k
Guillermo A. Herrera United States	32	2.3k 1.2×	574 1.0×	427 1.3×	279 0.9×	323 1.1×	150	3.3k
Carlo Zanon Italy	22	1.0k 0.5×	959 1.6×	246 0.8×	464 1.5×	203 0.7×	39	2.3k
Jonathan M. Yingling United States	26	2.7k 1.4×	1.3k 2.1×	128 0.4×	502 1.6×	251 0.9×	49	3.6k
Céline Callens France	27	1.0k 0.5×	670 1.1×	153 0.5×	480 1.5×	275 1.0×	83	2.2k
Thomas Winder United States	20	924 0.5×	903 1.5×	90 0.3×	212 0.7×	121 0.4×	35	2.0k
Belinda Cancilla United States	18	1.5k 0.8×	1.1k 2.0×	71 0.2×	673 2.2×	174 0.6×	38	2.7k
R. Scott Pearsall United States	25	1.4k 0.7×	300 0.5×	558 1.7×	376 1.2×	339 1.2×	62	2.4k
Reinhard Bos Netherlands	22	1.1k 0.6×	660 1.1×	118 0.4×	306 1.0×	172 0.6×	59	2.9k
Pamela M. Pollock Australia	34	2.6k 1.4×	1.3k 2.3×	76 0.2×	402 1.3×	188 0.7×	90	4.0k

Countries citing papers authored by Thomas Holcomb

Since Specialization

Citations

This map shows the geographic impact of Thomas Holcomb's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas Holcomb with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas Holcomb more than expected).

Fields of papers citing papers by Thomas Holcomb

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas Holcomb. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas Holcomb. The network helps show where Thomas Holcomb may publish in the future.

Co-authorship network of co-authors of Thomas Holcomb

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas Holcomb. A scholar is included among the top collaborators of Thomas Holcomb based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas Holcomb. Thomas Holcomb is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Wagle, Marie-Claire, Joseph Castillo, Shrividhya Srinivasan, et al.. (2020). Tumor Fusion Burden as a Hallmark of Immune Infiltration in Prostate Cancer. Cancer Immunology Research. 8(7). 844–850. 6 indexed citations

Goldstein, Leonard D., James Lee, Florian Gnad, et al.. (2016). Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers. Cell Reports. 16(10). 2605–2617. 151 indexed citations

Holcomb, Thomas, et al.. (2016). Introduction à la culture sourde. ERES eBooks. 4 indexed citations

Holcomb, Thomas, et al.. (2014). Systematically variable planktonic carbon metabolism along a land-to-lake gradient in a Great Lakes coastal zone. Journal of Plankton Research. 36(6). 1528–1542. 16 indexed citations

Shames, David S., Kristi Elkins, Kimberly Walter, et al.. (2013). Loss of NAPRT1 Expression by Tumor-Specific Promoter Methylation Provides a Novel Predictive Biomarker for NAMPT Inhibitors. Clinical Cancer Research. 19(24). 6912–6923. 59 indexed citations

Kim, Walter, Thomas Holcomb, Tom Januario, et al.. (2012). DNA Methylation Profiling Defines Clinically Relevant Biological Subsets of Non–Small Cell Lung Cancer. Clinical Cancer Research. 18(8). 2360–2373. 66 indexed citations

Yauch, Robert L., Gerrit J.P. Dijkgraaf, Bruno Alicke, et al.. (2009). Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma. Science. 326(5952). 572–574. 670 indexed citations breakdown →

Rudin, Charles M., Christine L. Hann, John Laterra, et al.. (2009). Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449. New England Journal of Medicine. 361(12). 1173–1178. 761 indexed citations breakdown →

Yauch, Robert L., Thomas Januario, Ling Fu, et al.. (2009). Abstract A44: Predictive biomarkers of efficacy to the hedgehog pathway inhibitor, GDC-0449, in advanced basal cell carcinoma and medulloblastoma in phase I studies. Molecular Cancer Therapeutics. 8(12_Supplement). A44–A44. 1 indexed citations

10.

Kong-Beltran, Monica, Somasekar Seshagiri, Jiping Zha, et al.. (2006). Somatic Mutations Lead to an Oncogenic Deletion of Met in Lung Cancer. Cancer Research. 66(1). 283–289. 372 indexed citations

11.

Holcomb, Thomas, et al.. (2000). Isolation, characterization and expression of a human brain mitochondrial glutaminase cDNA. Molecular Brain Research. 76(1). 56–63. 34 indexed citations

12.

Gstraunthaler, Gerhard, et al.. (2000). Differential expression and acid-base regulation of glutaminase mRNAs in gluconeogenic LLC-PK₁-FBPase⁺cells. American Journal of Physiology-Renal Physiology. 278(2). F227–F237. 34 indexed citations

13.

Liu, Wenlin, Elisabeth Feifel, Thomas Holcomb, et al.. (1998). PMA and staurosporine affect expression of the PCK gene in LLC-PK₁-F⁺cells. American Journal of Physiology-Renal Physiology. 275(3). F361–F369. 6 indexed citations

14.

Holcomb, Thomas, et al.. (1996). Promoter elements that mediate the pH response of PCK mRNA in LLC-PK1-F+ cells. American Journal of Physiology-Renal Physiology. 271(2). F340–F346. 19 indexed citations

15.

Holcomb, Thomas, Norman P. Curthoys, & Gerhard Gstraunthaler. (1995). Subcellular localization of PEPCK and metabolism of gluconeogenic substrains of renal cell lines. American Journal of Physiology-Cell Physiology. 268(2). C449–C457. 21 indexed citations

16.

Crandell, Robert A., et al.. (1968). A fatal illness associated with two viruses: An intermediate adenovirus type(21-16) and influenza A2. The Journal of Pediatrics. 72(4). 467–473. 15 indexed citations

17.

Haggard, Mary Ellen, Donald J. Fernbach, Thomas Holcomb, et al.. (1968). Vincristine in acute leukemia of childhood. Cancer. 22(2). 438–444. 30 indexed citations

18.

Woodhead, David M., et al.. (1968). Urothelial Implantation of Wilmsʼ Tumors. Annals of Surgery. 167(1). 127–131. 15 indexed citations

19.

Fernbach, Donald J., Kenneth M. Griffith, M. E. Haggard, et al.. (1966). Chemotherapy of Acute Leukemia in Childhood. New England Journal of Medicine. 275(9). 451–456. 20 indexed citations

20.

Holcomb, Thomas, et al.. (1959). Foreign body bronchoesophageal fistula*. Journal of Thoracic and Cardiovascular Surgery. 38(1). 115–119. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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