Seong A. Kang

8.6k total citations · 5 hit papers
22 papers, 6.6k citations indexed

About

Seong A. Kang is a scholar working on Molecular Biology, Pharmacology and Biochemistry. According to data from OpenAlex, Seong A. Kang has authored 22 papers receiving a total of 6.6k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 3 papers in Pharmacology and 2 papers in Biochemistry. Recurrent topics in Seong A. Kang's work include PI3K/AKT/mTOR signaling in cancer (17 papers), Protein Kinase Regulation and GTPase Signaling (11 papers) and Fungal Biology and Applications (3 papers). Seong A. Kang is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (17 papers), Protein Kinase Regulation and GTPase Signaling (11 papers) and Fungal Biology and Applications (3 papers). Seong A. Kang collaborates with scholars based in United States. Seong A. Kang's co-authors include David M. Sabatini, Carson C. Thoreen, Nathanael S. Gray, Timothy R. Peterson, Yasemin Sancak, Qingsong Liu, Taebo Sim, Jae Won Chang, Jianming Zhang and Laurie J. Reichling and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Seong A. Kang

22 papers receiving 6.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

2009 1.4k citations Carson C. Thoreen, Seong A. Kang et al. Journal of Biological Chemistry profile →
PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase

2007 984 citations Yasemin Sancak, Carson C. Thoreen et al. Molecular Cell profile →
mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

2011 965 citations Timothy R. Peterson, Shomit Sengupta et al. Cell profile →
DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

2009 950 citations Timothy R. Peterson, Mathieu Laplante et al. Cell profile →
The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

2011 840 citations Peggy P. Hsu, Seong A. Kang et al. Science profile →

Peers

Countries citing papers authored by Seong A. Kang

Since Specialization

Citations

This map shows the geographic impact of Seong A. Kang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Seong A. Kang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Seong A. Kang more than expected).

Fields of papers citing papers by Seong A. Kang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Seong A. Kang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Seong A. Kang. The network helps show where Seong A. Kang may publish in the future.

Co-authorship network of co-authors of Seong A. Kang

This figure shows the co-authorship network connecting the top 25 collaborators of Seong A. Kang. A scholar is included among the top collaborators of Seong A. Kang based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Seong A. Kang. Seong A. Kang is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters 2019 ·Cell chemical biology ·Seong A. Kang, David J. O’Neill, (unknown), (unknown), (unknown), Shomit Sengupta, Sarah J. Mahoney, Jessica J. Howell, Lisa Molz, Seung Hahm, George P. Vlasuk, Eddine Saiah	33
2	A small molecule inhibitor of Rheb selectively targets mTORC1 signaling 2018 ·Nature Communications ·Sarah J. Mahoney, Sridhar Narayan, Lisa Molz, (unknown), Seong A. Kang, George P. Vlasuk, Eddine Saiah	61
3	ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP 2016 ·Cancer Research ·Taru Muranen, Laura M. Selfors, Julie Hwang, Lisa L. Gallegos, Jonathan L. Coloff, Carson C. Thoreen, Seong A. Kang, David M. Sabatini, Gordon B. Mills, Joan S. Brugge	53
4	mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin 2013 ·Science ·Seong A. Kang, Michael E. Pacold, Christopher Cervantes, Do Young Lim, Hua Jane Lou, Kathleen Ottina, Nathanael S. Gray, Benjamin E. Turk, Michael B. Yaffe, David M. Sabatini	3
5	mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin 2013 ·DSpace@MIT (Massachusetts Institute of Technology) ·Christopher Cervantes, Daniel Lim, Seong A. Kang, Michael E. Pacold, Hua Jane Lou, Kathleen Ottina, Nathanael S. Gray, Benjamin E. Turk, Michael B. Yaffe, David M. Sabatini	349
6	mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway breakdown → 2011 ·Cell ·Timothy R. Peterson, Shomit Sengupta, Thurl E. Harris, (unknown), Seong A. Kang, (unknown), David A. Guertin, (unknown), Anne E. Carpenter, Brian N. Finck, David M. Sabatini	965
7	Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability 2011 ·Bioorganic & Medicinal Chemistry Letters ·Qingsong Liu, Jinhua Wang, Seong A. Kang, Carson C. Thoreen, Wooyoung Hur, Hwan Geun Choi, David Waller, Taebo Sim, David M. Sabatini, Nathanael S. Gray	10
8	The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling breakdown → 2011 ·Science ·Peggy P. Hsu, Seong A. Kang, Jonathan Rameseder, Yi Zhang, Kathleen Ottina, Daniel Lim, Timothy R. Peterson, Yongmun Choi, Nathanael S. Gray, Michael B. Yaffe, Jarrod A. Marto, David M. Sabatini	840
9	Development of ATP-Competitive mTOR Inhibitors 2011 ·Methods in molecular biology ·Qingsong Liu, Seong A. Kang, Carson C. Thoreen, Wooyoung Hur, Jinhua Wang, Jae Won Chang, Andrew L. Markhard, Jianming Zhang, Taebo Sim, David M. Sabatini, Nathanael S. Gray	37
10	Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer 2010 ·DSpace@MIT (Massachusetts Institute of Technology) ·Qingsong Liu, Jae Won Chang, Jinhua Wang, Seong A. Kang, Carson C. Thoreen, Andrew L. Markhard, Wooyoung Hur, Jianming Zhang, Taebo Sim, David M. Sabatini, Nathanael S. Gray	11
11	Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition 2010 ·Molecular Cell ·Calvin K. Yip, Kazuyoshi Murata, Thomas Walz, David M. Sabatini, Seong A. Kang	315
12	Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer 2010 ·Journal of Medicinal Chemistry ·Qingsong Liu, Jae Won Chang, Jinhua Wang, Seong A. Kang, Carson C. Thoreen, Andrew L. Markhard, Wooyoung Hur, Jianming Zhang, Taebo Sim, David M. Sabatini, Nathanael S. Gray	198
13	Native Capillary Isoelectric Focusing for the Separation of Protein Complex Isoforms and Subcomplexes 2010 ·Analytical Chemistry ·Bryan R. Fonslow, Seong A. Kang, Daniel R. Gestaut, Beth Graczyk, Trisha N. Davis, David M. Sabatini, John R. Yates	2
14	DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival breakdown → 2009 ·Cell ·Timothy R. Peterson, Mathieu Laplante, Carson C. Thoreen, Yasemin Sancak, Seong A. Kang, W. Michael Kuehl, Nathanael S. Gray, David M. Sabatini	950
15	An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1 breakdown → 2009 ·Journal of Biological Chemistry ·Carson C. Thoreen, Seong A. Kang, Jae Won Chang, Qingsong Liu, Jianming Zhang, Yi Gao, Laurie J. Reichling, Taebo Sim, David M. Sabatini, Nathanael S. Gray	1420
16	PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase breakdown → 2007 ·Molecular Cell ·Yasemin Sancak, Carson C. Thoreen, Timothy R. Peterson, Robert A. Lindquist, Seong A. Kang, Eric Spooner, Steven A. Carr, David M. Sabatini	984
17	Crystal Structure and Mechanism of Tryptophan 2,3-Dioxygenase, a Heme Enzyme Involved in Tryptophan Catabolism and in Quinolinate Biosynthesis^, 2006 ·Biochemistry ·Yang Zhang, Seong A. Kang, Tathagata Mukherjee, Shridhar Bale, Brian R. Crane, Tadhg P. Begley, S.E. Ealick	94
18	Solvent Isotope Effects on Interfacial Protein Electron Transfer in Crystals and Electrode Films 2006 ·Journal of the American Chemical Society ·Seong A. Kang, Kevin R. Hoke, Brian R. Crane	13
19	Effects of interface mutations on association modes and electron-transfer rates between proteins 2005 ·Proceedings of the National Academy of Sciences ·Seong A. Kang, Brian R. Crane	41
20	Electron Transfer between Cytochrome c and Cytochome c Peroxidase in Single Crystals 2004 ·Journal of the American Chemical Society ·Seong A. Kang, (unknown), Brian R. Crane	28

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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