Rudolf Grosschedl

31.4k total citations · 9 hit papers
160 papers, 25.2k citations indexed

About

Rudolf Grosschedl is a scholar working on Molecular Biology, Immunology and Genetics. According to data from OpenAlex, Rudolf Grosschedl has authored 160 papers receiving a total of 25.2k indexed citations (citations by other indexed papers that have themselves been cited), including 107 papers in Molecular Biology, 64 papers in Immunology and 26 papers in Genetics. Recurrent topics in Rudolf Grosschedl's work include T-cell and B-cell Immunology (45 papers), Immune Cell Function and Interaction (37 papers) and Genomics and Chromatin Dynamics (29 papers). Rudolf Grosschedl is often cited by papers focused on T-cell and B-cell Immunology (45 papers), Immune Cell Function and Interaction (37 papers) and Genomics and Chromatin Dynamics (29 papers). Rudolf Grosschedl collaborates with scholars based in United States, Germany and Japan. Rudolf Grosschedl's co-authors include Klaus Giese, Laurakay Bruhn, Joan Galcerán, Max L. Birnstiel, Isabel Fariñas, Jürgen Behrens, Walter Birchmeier, Michael Kühl, Doris Wedlich and Jens Peter von Kries and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Rudolf Grosschedl

160 papers receiving 24.5k citations

Hit Papers

Functional interaction of... 1985 2026 1998 2012 1996 2006 1994 1994 1988 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Functional interaction of β-catenin with the transcription factor LEF-1
    1996 2.5k citations Rudolf Grosschedl et al. profile →
  2. LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
    2006 964 citations Rudolf Grosschedl et al. profile →
  3. Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.
    1994 801 citations Rudolf Grosschedl et al. Genes & Development profile →
  4. HMG domain proteins: architectural elements in the assembly of nucleoprotein structures
    1994 695 citations Rudolf Grosschedl et al. profile →
  5. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
    1988 626 citations Rudolf Grosschedl et al. profile →
  6. The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures
    1992 598 citations Rudolf Grosschedl et al. profile →
  7. Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements
    1985 541 citations Rudolf Grosschedl et al. profile →
  8. Failure of B-cell differentiation in mice lacking the transcription factor EBF
    1995 541 citations Rudolf Grosschedl et al. profile →
  9. LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]
    1991 534 citations Adam Travis, Rudolf Grosschedl et al. Genes & Development profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Rudolf Grosschedl United States 84 18.4k 5.0k 4.1k 2.7k 2.1k 160 25.2k
Cornelis Murre United States 77 19.1k 1.0× 8.4k 1.7× 3.4k 0.8× 2.9k 1.0× 2.5k 1.2× 151 27.6k
Jeffrey M. Leiden United States 69 10.8k 0.6× 5.0k 1.0× 3.3k 0.8× 2.3k 0.8× 1.6k 0.7× 145 18.2k
Debra J. Gilbert United States 69 10.8k 0.6× 3.6k 0.7× 3.0k 0.7× 2.3k 0.8× 1.3k 0.6× 256 17.7k
Richard Treisman United Kingdom 70 19.1k 1.0× 2.8k 0.6× 3.2k 0.8× 3.8k 1.4× 2.5k 1.2× 116 25.1k
Robert N. Eisenman United States 82 25.2k 1.4× 2.8k 0.6× 5.1k 1.3× 5.8k 2.1× 2.9k 1.4× 204 30.7k
Haruhiko Koseki Japan 90 19.2k 1.0× 8.5k 1.7× 4.3k 1.1× 3.2k 1.2× 2.1k 1.0× 388 29.9k
Toru Nakano Japan 68 12.9k 0.7× 4.6k 0.9× 2.7k 0.7× 1.8k 0.7× 1.8k 0.8× 208 18.9k
Tadashi Yamamoto Japan 77 13.2k 0.7× 3.3k 0.7× 2.0k 0.5× 5.0k 1.8× 2.1k 1.0× 400 22.4k
Colin L. Stewart United States 96 22.7k 1.2× 6.8k 1.4× 4.9k 1.2× 2.4k 0.9× 1.4k 0.7× 217 33.9k
James L. Manley United States 111 35.1k 1.9× 2.7k 0.5× 3.6k 0.9× 2.5k 0.9× 3.3k 1.6× 348 39.1k

Countries citing papers authored by Rudolf Grosschedl

Since Specialization
Citations

This map shows the geographic impact of Rudolf Grosschedl's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rudolf Grosschedl with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rudolf Grosschedl more than expected).

Fields of papers citing papers by Rudolf Grosschedl

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rudolf Grosschedl. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rudolf Grosschedl. The network helps show where Rudolf Grosschedl may publish in the future.

Co-authorship network of co-authors of Rudolf Grosschedl

This figure shows the co-authorship network connecting the top 25 collaborators of Rudolf Grosschedl. A scholar is included among the top collaborators of Rudolf Grosschedl based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rudolf Grosschedl. Rudolf Grosschedl is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Zhou, Yeqiao, Sora Yoon, Guy Nir, et al.. (2025). Lineage-determining transcription factors constrain cohesin to drive multi-enhancer oncogene regulation. Nature Cell Biology. 28(1). 149–165. 1 indexed citations
2.
Andreani, Virginia, Senthilkumar Ramamoorthy, Reinhard Fässler, & Rudolf Grosschedl. (2022). Integrin β1 regulates marginal zone B cell differentiation and PI3K signaling. The Journal of Experimental Medicine. 220(1). 10 indexed citations
3.
Wang, Yuanting, Nikolay Zolotarev, Chengyuan Yang, et al.. (2020). A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin. Immunity. 53(6). 1151–1167.e6. 51 indexed citations
4.
Rodríguez‐Gil, Alfonso, Jochen Wilhelm, Chen-Yuan Charlie Yang, et al.. (2017). The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription. Scientific Reports. 7(1). 3547–3547. 23 indexed citations
5.
Yang, Chengyuan, Senthilkumar Ramamoorthy, Sören Boller, et al.. (2016). Interaction of CCR4–NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis. Genes & Development. 30(20). 2310–2324. 24 indexed citations
6.
Rosenbaum, Marc, et al.. (2014). MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress. Genes & Development. 28(11). 1165–1178. 91 indexed citations
7.
Zhang, Jin, Qisheng Tu, Rudolf Grosschedl, et al.. (2011). Roles of SATB2 in Osteogenic Differentiation and Bone Regeneration. Tissue Engineering Part A. 17(13-14). 1767–1776. 82 indexed citations
8.
Treiber, Nora, Thomas Treiber, Georg Zocher, & Rudolf Grosschedl. (2010). Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins. Genes & Development. 24(20). 2270–2275. 34 indexed citations
9.
Schneider, Robert & Rudolf Grosschedl. (2007). Dynamics and interplay of nuclear architecture, genome organization, and gene expression. Genes & Development. 21(23). 3027–3043. 315 indexed citations
10.
Grosschedl, Rudolf, et al.. (2005). Wnt Signaling in Lymphopoiesis. Current topics in microbiology and immunology. 290. 225–252. 15 indexed citations
11.
Gregorieff, Alex, Rudolf Grosschedl, & Hans Clevers. (2004). Hindgut defects and transformation of the gastro‐intestinal tract in Tcf4−/−/Tcf1−/− embryos. The EMBO Journal. 23(8). 1825–1833. 102 indexed citations
12.
Roth, Wera, Claudio Sustmann, Matthias Kieslinger, et al.. (2004). PIASy-Deficient Mice Display Modest Defects in IFN and Wnt Signaling. The Journal of Immunology. 173(10). 6189–6199. 70 indexed citations
13.
Kokubu, Chikara, U. Heinzmann, Norio Sakai, et al.. (2004). Skeletal defects inringelschwanzmutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis. Development. 131(21). 5469–5480. 145 indexed citations
14.
Medina, Kay L., Jagan M.R. Pongubala, Karen L. Reddy, et al.. (2004). Assembling a Gene Regulatory Network for Specification of the B Cell Fate. Developmental Cell. 7(4). 607–617. 182 indexed citations
15.
Kratochwil, Klaus, et al.. (2002). FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1 −/− mice. Genes & Development. 16(24). 3173–3185. 211 indexed citations
16.
Fernández, Luis Ángel, Michael Winkler, & Rudolf Grosschedl. (2001). Matrix Attachment Region-Dependent Function of the Immunoglobulin μ Enhancer Involves Histone Acetylation at a Distance without Changes in Enhancer Occupancy. Molecular and Cellular Biology. 21(1). 196–208. 77 indexed citations
17.
Pérez-Alvarado, Gabriela C., et al.. (2000). Identification of the regions involved in DNA binding by the mouse PEBP2α protein. FEBS Letters. 470(2). 125–130. 15 indexed citations
18.
Fernández, Luis Ángel, Michael Winkler, William C. Forrester, Thomas Jenuwein, & Rudolf Grosschedl. (1998). Nuclear Matrix Attachment Regions Confer Long-range Function upon the Immunoglobulin   Enhancer. Cold Spring Harbor Symposia on Quantitative Biology. 63(0). 515–524. 12 indexed citations
19.
Travis, Adam, James Hagman, Lena H. Hwang, & Rudolf Grosschedl. (1993). Purification of Early-B-Cell Factor and Characterization of its DNA-Binding Specificity. Molecular and Cellular Biology. 13(6). 3392–3400. 20 indexed citations
20.
Travis, Adam, James Hagman, & Rudolf Grosschedl. (1991). Heterogeneously Initiated Transcription from the Pre-B- and B-Cell-Specific mb-1 Promoter: Analysis of the Requirement for Upstream Factor-Binding Sites and Initiation Site Sequences. Molecular and Cellular Biology. 11(11). 5756–5766. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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