Frank Grosveld

50.7k total citations · 12 hit papers
391 papers, 38.5k citations indexed

About

Frank Grosveld is a scholar working on Molecular Biology, Genetics and Genetics. According to data from OpenAlex, Frank Grosveld has authored 391 papers receiving a total of 38.5k indexed citations (citations by other indexed papers that have themselves been cited), including 289 papers in Molecular Biology, 85 papers in Genetics and 63 papers in Genetics. Recurrent topics in Frank Grosveld's work include Genomics and Chromatin Dynamics (86 papers), Hemoglobinopathies and Related Disorders (52 papers) and CRISPR and Genetic Engineering (51 papers). Frank Grosveld is often cited by papers focused on Genomics and Chromatin Dynamics (86 papers), Hemoglobinopathies and Related Disorders (52 papers) and CRISPR and Genetic Engineering (51 papers). Frank Grosveld collaborates with scholars based in Netherlands, United Kingdom and United States. Frank Grosveld's co-authors include Wouter de Laat, Peter Fraser, George Kollias, David R. Greaves, Robert‐Jan Palstra, Erik Splinter, Sjaak Philipsen, Niels Galjart, John Strouboulis and Niall Dillon and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Frank Grosveld

389 papers receiving 37.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 1.7k citations Frank Grosveld et al. profile →
Looping and Interaction between Hypersensitive Sites in the Active β-globin Locus

2002 1.0k citations Frank Grosveld et al. profile →
Atherosclerotic Lesion Size and Vulnerability Are Determined by Patterns of Fluid Shear Stress

2006 787 citations Rien van Haperen, Frank Grosveld et al. profile →
A human monoclonal antibody blocking SARS-CoV-2 infection

2020 729 citations Chunyan Wang, Wentao Li et al. Nature Communications profile →
Development of hematopoietic stem cell activity in the mouse embryo

1994 695 citations John Strouboulis, Frank Grosveld et al. profile →
Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

2006 659 citations Frank Grosveld et al. Nature Cell Biology profile →
Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction

2010 614 citations Wilfred F. J. van IJcken, Peter J. van der Spek et al. PLoS ONE profile →
Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells

2013 566 citations Jessica Zuin, Petros Kolovos et al. Proceedings of the National Academy of Sciences profile →
Visualization of Microtubule Growth in Cultured Neurons via the Use of EB3-GFP (End-Binding Protein 3-Green Fluorescent Protein)

2003 548 citations Т. Ф. Степанова, Casper C. Hoogenraad et al. profile →
CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus

2006 546 citations Frank Grosveld, Niels Galjart et al. profile →
Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

1995 500 citations Frank Grosveld et al. profile →
Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress.

1995 470 citations Frank Grosveld et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Frank Grosveld Netherlands	105	27.5k	7.1k	5.2k	4.4k	3.8k	391	38.5k
D.N. Cooper United Kingdom	90	19.9k 0.7×	10.5k 1.5×	2.4k 0.5×	3.7k 0.8×	1.9k 0.5×	568	34.9k
Uta Francke United States	99	24.1k 0.9×	14.5k 2.0×	4.0k 0.8×	4.8k 1.1×	1.7k 0.4×	503	41.9k
Stylianos E. Antonarakis Switzerland	102	21.9k 0.8×	13.3k 1.9×	1.9k 0.4×	2.8k 0.6×	4.1k 1.1×	602	40.8k
Janet Rossant Canada	130	49.6k 1.8×	11.9k 1.7×	7.2k 1.4×	4.7k 1.1×	2.0k 0.5×	397	61.8k
David E. Housman United States	104	32.2k 1.2×	9.2k 1.3×	2.7k 0.5×	3.0k 0.7×	2.1k 0.5×	329	47.8k
Roel Nusse United States	99	43.6k 1.6×	8.1k 1.1×	6.3k 1.2×	3.8k 0.9×	1.8k 0.5×	208	55.1k
Steven L. McKnight United States	87	26.7k 1.0×	6.2k 0.9×	2.5k 0.5×	4.3k 1.0×	1.2k 0.3×	149	39.0k
Mark Groudine United States	89	27.1k 1.0×	6.2k 0.9×	1.5k 0.3×	2.8k 0.6×	2.2k 0.6×	223	32.6k
Michael D. Waterfield United Kingdom	80	20.8k 0.8×	3.7k 0.5×	5.2k 1.0×	4.3k 1.0×	2.5k 0.6×	187	32.3k
J. Michael Bishop United States	116	33.0k 1.2×	11.4k 1.6×	4.5k 0.9×	5.7k 1.3×	1.6k 0.4×	356	48.6k

Countries citing papers authored by Frank Grosveld

Since Specialization

Citations

This map shows the geographic impact of Frank Grosveld's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Grosveld with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Grosveld more than expected).

Fields of papers citing papers by Frank Grosveld

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Grosveld. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Grosveld. The network helps show where Frank Grosveld may publish in the future.

Co-authorship network of co-authors of Frank Grosveld

This figure shows the co-authorship network connecting the top 25 collaborators of Frank Grosveld. A scholar is included among the top collaborators of Frank Grosveld based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank Grosveld. Frank Grosveld is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bindels, Eric M., Remco M. Hoogenboezem, Mathijs A. Sanders, et al.. (2025). Distinct roles of Atf3 , Zfp711 and Bcl6b in early embryonic hematopoietic and endothelial lineage specification. Development. 152(23).

Yavuz, Selçuk, Simon Linder, Wiggert A. van Cappellen, et al.. (2023). Compartmentalization of androgen receptors at endogenous genes in living cells. Nucleic Acids Research. 51(20). 10992–11009. 7 indexed citations

Wang, Chunyan, Emma L. Hesketh, Wentao Li, et al.. (2022). Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes. Nature Communications. 13(1). 2921–2921. 20 indexed citations

Wang, Chunyan, Rien van Haperen, Francisco J. Gutierrez-Alvarez, et al.. (2021). A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies. Nature Communications. 12(1). 1715–1715. 95 indexed citations

Miyata, Masato, Nynke Gillemans, Dorit Hockman, et al.. (2020). An evolutionarily ancient mechanism for regulation of hemoglobin expression in vertebrate red cells. Blood. 136(3). 269–278. 14 indexed citations

Knoch, Tobias, Malte Wachsmuth, Nick Kepper, et al.. (2016). The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes. Epigenetics & Chromatin. 9(1). 19 indexed citations

Giraud, Guillaume, Ralph Stadhouders, Andrea Conidi, et al.. (2014). NLS-tagging: an alternative strategy to tag nuclear proteins. Nucleic Acids Research. 42(21). e163–e163. 8 indexed citations

Stadhouders, Ralph, Süleyman Aktuna, Supat Thongjuea, et al.. (2014). HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. Journal of Clinical Investigation. 124(4). 1699–1710. 142 indexed citations

Huang, Yadi, Joshua K. Ochieng, Sigrid Swagemakers, et al.. (2013). Hypoxia Inducible Factor 3α Plays a Critical Role in Alveolarization and Distal Epithelial Cell Differentiation during Mouse Lung Development. PLoS ONE. 8(2). e57695–e57695. 24 indexed citations

10.

Bakker, Elvira R. M., Jason C. Mills, Sigrid M. A. Swagemakers, et al.. (2012). SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype. Journal of Molecular Cell Biology. 4(6). 377–385. 51 indexed citations

11.

Huang, Yadi, Marjon Buscop‐van Kempen, Anne Boerema‐de Munck, et al.. (2011). Hypoxia-Inducible Factor 2α Plays a Critical Role in the Formation of Alveoli and Surfactant. American Journal of Respiratory Cell and Molecular Biology. 46(2). 224–232. 39 indexed citations

12.

Cappellen, Wiggert A. van, Jeffrey van Haren, George D. Tsibidis, et al.. (2008). Dynamic behavior of GFP–CLIP-170 reveals fast protein turnover on microtubule plus ends. The Journal of Cell Biology. 180(4). 729–737. 97 indexed citations

13.

Meier, N., Patrick Rodriguez, John Strouboulis, et al.. (2006). Novel binding partners of Ldb1 are required for haematopoietic development. Development. 133(24). 4913–4923. 105 indexed citations

14.

Dekker, Sylvia, Rudi W. Hendriks, George Panayotou, et al.. (2006). Generation of heavy-chain-only antibodies in mice. Proceedings of the National Academy of Sciences. 103(41). 15130–15135. 60 indexed citations

15.

Mimori‐Kiyosue, Yuko, Ilya Grigoriev, Gideon Lansbergen, et al.. (2005). CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. The Journal of Cell Biology. 168(1). 141–153. 333 indexed citations

16.

Lansbergen, Gideon, Yulia Komarova, Mauro Modesti, et al.. (2004). Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. The Journal of Cell Biology. 166(7). 1003–1014. 148 indexed citations

17.

Boer, Ernie de, Patrick Rodriguez, Edgar Bonte, et al.. (2003). Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice. Proceedings of the National Academy of Sciences. 100(13). 7480–7485. 336 indexed citations

18.

Akhmanova, Anna, Phebe S. Wulf, Elaine Del Nery, et al.. (2002). Bicaudal-D regulates COPI-independent Golgi–ER transport by recruiting the dynein–dynactin motor complex. Nature Cell Biology. 4(12). 986–992. 314 indexed citations

19.

Wit, Ton de, Frank Grosveld, & Dubravka Drabek. (2002). The tomato RNA-directed RNA polymerase has no effect on gene silencing by RNA interference in transgenic mice. Transgenic Research. 11(3). 305–310. 6 indexed citations

20.

Vidal, Miguel, et al.. (1990). Differences in human cell lines to support stable replication of Epstein-Barr virus-based vectors. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1048(2-3). 171–177. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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