Frank Grosveld

50.7k citations

391 papers · 38.5k indexed · 12 hit papers · h-index 105

Molecular Biology top 0.05%
Genetics top 0.05%
Cell Biology top 0.05%
Immunology top 0.2%
Genetics top 0.1%

Co-authors: Wouter de Laat Peter Fraser George Kollias David R. Greaves Robert‐Jan Palstra Erik Splinter Sjaak Philipsen Niels Galjart
Topics: Genomics and Chromatin Dynamics (86 papers)Hemoglobinopathies and Related Disorders (52 papers)CRISPR and Genetic Engineering (51 papers)
Cited by: Molecular Biology Genetics Cell Biology
Journals: Nature Science Cell
Partner nations: Netherlands United Kingdom United States

In The Last Decade

Frank Grosveld

389 papers receiving 37.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 1.7k citations Frank Grosveld et al. profile →
Looping and Interaction between Hypersensitive Sites in the Active β-globin Locus

2002 1.0k citations Robert‐Jan Palstra, Erik Splinter et al. profile →
Atherosclerotic Lesion Size and Vulnerability Are Determined by Patterns of Fluid Shear Stress

2006 787 citations Rien van Haperen, Frank Grosveld et al. profile →
A human monoclonal antibody blocking SARS-CoV-2 infection

2020 729 citations Chunyan Wang, Wentao Li et al. Nature Communications profile →
Development of hematopoietic stem cell activity in the mouse embryo

1994 695 citations John Strouboulis, Frank Grosveld et al. profile →
Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

2006 659 citations Frank Grosveld et al. profile →
Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction

2010 614 citations Wilfred F. J. van IJcken, Frank Grosveld et al. profile →
Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells

2013 566 citations Jessica Zuin, Petros Kolovos et al. Proceedings of the National Academy of Sciences profile →
Visualization of Microtubule Growth in Cultured Neurons via the Use of EB3-GFP (End-Binding Protein 3-Green Fluorescent Protein)

2003 548 citations Casper C. Hoogenraad, Gideon Lansbergen et al. profile →
CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus

2006 546 citations Erik Splinter, Jurgen Kooren et al. profile →
Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

1995 500 citations Frank Grosveld et al. profile →
Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress.

1995 470 citations Frank Grosveld et al. profile →

Peers

Countries citing papers authored by Frank Grosveld

Since Specialization

Citations

This map shows the geographic impact of Frank Grosveld's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Grosveld with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Grosveld more than expected).

Fields of papers citing papers by Frank Grosveld

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Grosveld. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Grosveld. The network helps show where Frank Grosveld may publish in the future.

Co-authorship network of co-authors of Frank Grosveld

This figure shows the co-authorship network connecting the top 25 collaborators of Frank Grosveld. A scholar is included among the top collaborators of Frank Grosveld based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank Grosveld. Frank Grosveld is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Distinct roles of Atf3 , Zfp711 and Bcl6b in early embryonic hematopoietic and endothelial lineage specification 2025 ·Development ·(unknown),(unknown),(unknown),Eric M. Bindels,Remco M. Hoogenboezem,(unknown),Mathijs A. Sanders,(unknown),Ahmet Korkmaz,Joost Gribnau,Jeffrey van Haren,Danny Huylebroeck,Eskeatnaf Mulugeta,Frank Grosveld	0
2	Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein 2024 ·Nature Communications ·Wenjuan Du,(unknown),Dubravka Drabek,Rien van Haperen,(unknown),(unknown),Ieva Drulyte,Frank J. M. van Kuppeveld,Frank Grosveld,Daniel L. Hurdiss,Berend‐Jan Bosch	5
3	Compartmentalization of androgen receptors at endogenous genes in living cells 2023 ·Nucleic Acids Research ·Selçuk Yavuz,(unknown),(unknown),Simon Linder,Wiggert A. van Cappellen,Alex L. Nigg,Tsion E. Abraham,Johan A. Slotman,(unknown),Raymond A. Poot,Wilbert Zwart,Martin E. van Royen,Frank Grosveld,Ihor Smal,Adriaan B. Houtsmuller	7
4	Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes 2022 ·Nature Communications ·Chunyan Wang,Emma L. Hesketh,(unknown),Wentao Li,(unknown),Dubravka Drabek,Rien van Haperen,(unknown),Frank J. M. van Kuppeveld,Frank Grosveld,Neil A. Ranson,Joost Snijder,Raoul J. de Groot,Daniel L. Hurdiss,Berend‐Jan Bosch	20
5	A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies 2021 ·Nature Communications ·Chunyan Wang,Rien van Haperen,Francisco J. Gutierrez-Alvarez,Wentao Li,Nisreen M.A. Okba,Irina C. Albulescu,Ivy Widjaja,Brenda van Dieren,Raúl Fernández‐Delgado,Isabel Sola,Daniel L. Hurdiss,Olalekan Daramola,Frank Grosveld,Frank J. M. van Kuppeveld,Bart L. Haagmans,Luis Enjuanes,Dubravka Drabek,Berend‐Jan Bosch	95
6	An evolutionarily ancient mechanism for regulation of hemoglobin expression in vertebrate red cells 2020 ·Blood ·Masato Miyata,Nynke Gillemans,Dorit Hockman,Jeroen Demmers,Jan‐Fang Cheng,Jun Hou,(unknown),Christopher A. Fisher,Stephen Taylor,Richard J. Gibbons,(unknown),Leonard I. Zon,Frank Grosveld,Eskeatnaf Mulugeta,Tatjana Sauka‐Spengler,Douglas R. Higgs,Sjaak Philipsen	14
7	Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B 2020 ·Human Genomics ·Petros Papadopoulos,(unknown),Iris M. De Cuyper,Vilma Barroca,Daniel Lewandowski,Zahra Kadri,(unknown),(unknown),Nynke Gillemans,(unknown),Frank Grosveld,Rob van Zwieten,Sjaak Philipsen,Muriel Vernet,Laura Gutiérrez,George P. Patrinos	5
8	Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb 2020 ·Development ·(unknown),Elke Stappers,Ruben Dries,Elise Peyre,Veronique van den Berghe,Andrea Conidi,(unknown),Annick Francis,(unknown),Agata Stryjewska,(unknown),Elke Maas,Ihor Smal,Wilfred F. J. van IJcken,Frank Grosveld,Laurent Nguyen,Danny Huylebroeck,Eve Seuntjens	6
9	A human monoclonal antibody blocking SARS-CoV-2 infectionbreakdown → 2020 ·Nature Communications ·Chunyan Wang,Wentao Li,Dubravka Drabek,Nisreen M.A. Okba,Rien van Haperen,Albert D. M. E. Osterhaus,Frank J. M. van Kuppeveld,Bart L. Haagmans,Frank Grosveld,Berend‐Jan Bosch	729
10	A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury 2019 ·Journal of the American Society of Nephrology ·I. V. Grigorieva,André Oszwald,Elena Grigorieva,Helga Schachner,(unknown),Tammo Ostendorf,Jürgen Floege,Maja T. Lindenmeyer,Clemens D. Cohen,Ulf Panzer,Christof Aigner,Alice Schmidt,Frank Grosveld,Rajesh V. Thakker,Andrew J. Rees,Renate Kain	29
11	The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes 2016 ·Epigenetics & Chromatin ·Tobias Knoch,Malte Wachsmuth,Nick Kepper,(unknown),(unknown),A. Imam,Petros Kolovos,Jessica Zuin,Christel Kockx,Rutger W. W. Brouwer,Harmen J.G. van de Werken,Wilfred F. J. van IJcken,Kerstin S. Wendt,Frank Grosveld	19
12	r3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing data 2013 ·Nucleic Acids Research ·Supat Thongjuea,Ralph Stadhouders,Frank Grosveld,Éric Soler,Boris Lenhard	73
13	Dynamic behavior of GFP–CLIP-170 reveals fast protein turnover on microtubule plus ends 2008 ·The Journal of Cell Biology ·(unknown),Wiggert A. van Cappellen,Jeffrey van Haren,George D. Tsibidis,Anna Akhmanova,Tobias Knoch,Frank Grosveld,Niels Galjart	97
14	Chapter 5 Three‐Dimensional Organization of Gene Expression in Erythroid Cells 2008 ·Current topics in developmental biology ·Wouter de Laat,Petra Klous,Jurgen Kooren,Daan Noordermeer,Robert‐Jan Palstra,Marieke Simonis,Erik Splinter,Frank Grosveld	60
15	Novel binding partners of Ldb1 are required for haematopoietic development 2006 ·Development ·N. Meier,(unknown),Patrick Rodriguez,John Strouboulis,Maria Monti,Jeroen Krijgsveld,Martin Gering,Roger Patient,Arnd Hostert,Frank Grosveld	105
16	Generation of heavy-chain-only antibodies in mice 2006 ·Proceedings of the National Academy of Sciences ·(unknown),Sylvia Dekker,Rudi W. Hendriks,George Panayotou,Alexandra van Remoortere,(unknown),Frank Grosveld,Dubravka Drabek	60
17	CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex 2005 ·The Journal of Cell Biology ·Yuko Mimori‐Kiyosue,Ilya Grigoriev,Gideon Lansbergen,Hiroyuki Sasaki,Chiyuki Matsui,Fedor F. Severin,Niels Galjart,Frank Grosveld,Ivan A. Vorobjev,Shöichiro Tsukita,Anna Akhmanova	333
18	Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization 2004 ·The Journal of Cell Biology ·Gideon Lansbergen,Yulia Komarova,Mauro Modesti,Claire Wyman,Casper C. Hoogenraad,Holly V. Goodson,Régis Lemaitre,David Drechsel,Erik van Munster,Theodorus W. J. Gadella,Frank Grosveld,Niels Galjart,Gary G. Borisy,Anna Akhmanova	148
19	Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice 2003 ·Proceedings of the National Academy of Sciences ·Ernie de Boer,Patrick Rodriguez,Edgar Bonte,Jeroen Krijgsveld,Eleni Katsantoni,Albert J. R. Heck,Frank Grosveld,John Strouboulis	336
20	3C Technology: Analyzing the Spatial Organization of Genomic Loci In Vivo 2003 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Erik Splinter,Frank Grosveld,Wouter de Laat	102

About Frank Grosveld

Frank Grosveld is a scholar working on Genetics, Molecular Biology and Cell Biology, having authored 391 papers that have together received 38.5k indexed citations. Recurring topics across this work include Genomics and Chromatin Dynamics (86 papers), Hemoglobinopathies and Related Disorders (52 papers) and CRISPR and Genetic Engineering (51 papers). The work is most often cited by research in Molecular Biology (27.5k citations), Genetics (3.8k citations) and Cell Biology (5.2k citations). Frank Grosveld has collaborated with scholars based in Netherlands, United Kingdom and United States. Frequent co-authors include Wouter de Laat, Peter Fraser, George Kollias, David R. Greaves, Robert‐Jan Palstra, Erik Splinter, Sjaak Philipsen, Niels Galjart, John Strouboulis and Niall Dillon. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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