Ruben L. Smeets

3.7k citations

46 papers · 2.0k indexed · 1 hit paper · h-index 21

Immunology top 2%
- T-cell and B-cell Immunology 7
- Immune Cell Function and Interaction 6
- Immune Response and Inflammation 6
- interferon and immune responses 5
- Immunotherapy and Immune Responses 5
- Psoriasis: Treatment and Pathogenesis 5
Rheumatology top 2%
Oncology top 10%
- Cancer Immunotherapy and Biomarkers 4
Hematology top 10%
Transplantation top 10%
Pathology and Forensic Medicine
- Systemic Sclerosis and Related Diseases 5

Co-authors: Hans J. P. M. Koenen Irma Joosten Annemieke M. H. Boots Paul Vink Esther van Rijssen Wim B. van den Berg Leo A. B. Joosten Fons A. J. van de Loo
Cited by: Immunology Rheumatology Oncology
Journals: New England Journal of Medicine (1 paper)Blood (1 paper)The Journal of Immunology (1 paper)
Partner nations: Netherlands Germany United States

In The Last Decade

Ruben L. Smeets

42 papers receiving 2.0k citations

Hit Papers

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Peers

Countries citing papers authored by Ruben L. Smeets

Since Specialization

Citations

This map shows the geographic impact of Ruben L. Smeets's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ruben L. Smeets with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ruben L. Smeets more than expected).

Fields of papers citing papers by Ruben L. Smeets

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ruben L. Smeets. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ruben L. Smeets. The network helps show where Ruben L. Smeets may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Ruben L. Smeets, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ruben L. Smeets Line = papers co-authored together Ruben L. Smeets links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Ex vivo pembrolizumab pharmacology for personalized PD-1 inhibitor therapy reveals a critical gap between receptor occupancy and T cell functionality International Immunopharmacology ·Judith D J Verdonk,Berber Piet,Rob ter Heine,Michel M. van den Heuvel,Ruben L. Smeets,Hans J. P. M. Koenen	2025	0
2	Systemic sclerosis-associated pulmonary arterial hypertension is characterized by a distinct peripheral T helper cell profile Lara D. Veeken ·Theodoros Ioannis Papadimitriou,J. Lemmers,A. van Caam,Jacqueline L Vos,E.L. Vitters,Lizan Stinissen,Sander I. van Leuven,Marije I. Koenders,P.M. van der Kraan,Hans J. P. M. Koenen,Ruben L. Smeets,Robin Nijveldt,Madelon C Vonk,Rogier M. Thurlings	2024	1
3	Development and validation of a bioanalytical assay for the measurement of total and unbound teicoplanin in human serum Journal of Antimicrobial Chemotherapy ·Johan Mouton,J. A. M. Raaijmakers,M. Botterblom,M Toonen,Rob ter Heine,Ruben L. Smeets,Roger J. M. Brüggemann,Lindsey te Brake,Nynke G L Jager	2023	5
4	Evidence‐based rationale for low dose nivolumab in critically ill patients with sepsis‐induced immunosuppression Clinical and Translational Science ·Demy A. C. van den Haak,Leila S. Otten,Hans J. P. M. Koenen,Ruben L. Smeets,Berber Piet,Peter Pickkers,Matthijs Kox,Rob ter Heine	2023	10
5	Molecular mechanisms and treatment responses of pulmonary fibrosis in severe COVID-19 Respiratory Research ·Emma J. Kooistra,K. Dahm,Antonius E. van Herwaarden,Jelle Gerretsen,Melanie Nuesch Germano,Karoline Mauer,Ruben L. Smeets,Sjef van der Velde,Maarten J. W. van den Berg,Johannes G. van der Hoeven,Anna C. Aschenbrenner,Joachim L. Schultze,Thomas Ulas,Matthijs Kox,Peter Pickkers	2023	10
6	Severe Immune-Related Enteritis after In Utero Exposure to Pembrolizumab New England Journal of Medicine ·Manuel A. Baarslag,Joosje H. Heimovaara,Jessica S.W. Borgers,Koen van Aerde,Hans J. P. M. Koenen,Ruben L. Smeets,Pauline L.M. Buitelaar,Dick Pluim,Shoko Vos,Stefanie Henriet,Jan Willem B. de Groot,Martine van Grotel,Hilde Rosing,Jos H. Beijnen,Alwin D. R. Huitema,John B.A.G. Haanen,Frédéric Amant,N. Gierenz	2023	14
7	Validation of non-invasive point of care blood content analysis using the TensorTip™ MTX device: a method comparison study Clinical Chemistry and Laboratory Medicine (CCLM) ·Sjoerd Servaas,Silke de Vreede,Ruben L. Smeets,An K. Stroobants,Lucas T. van Eijk,Ignacio Malagon,Cornelis Slagt	2023	1
8	CD7 activation regulates cytotoxicity-driven pathology in systemic sclerosis, yielding a target for selective cell depletion Annals of the Rheumatic Diseases ·Theodoros Ioannis Papadimitriou,Prashant Singh,A. van Caam,Birgitte Walgreen,Mark A.J. Gorris,E.L. Vitters,Iris L. van Ingen,Marije I. Koenders,Ruben L. Smeets,Madelon C Vonk,Jolanda M de Vries,P.M. van der Kraan,Ypke van Oosterhout,Martijn A. Huynen,Hans J. P. M. Koenen,Rogier M. Thurlings	2023	5
9	Trio-based whole exome sequencing in patients with suspected sporadic inborn errors of immunity: A retrospective cohort study eLife ·Anne Hebert,Annet Simons,Janneke Schuurs-Hoeijmakers,Hans JPM Koenen,Evelien Zonneveld‐Huijssoon,Stefanie Henriet,Ellen Schatorjé,Esther Hoppenreijs,Erika Leenders,E. Janssen,Gijs W.E. Santen,Sonja A. de Munnik,Simon V. van Reijmersdal,Esther van Rijssen,Simone Kersten,Mihai G. Netea,Ruben L. Smeets,Frank L. van de Veerdonk,Alexander Hoischen,Caspar I. van der Made	2022	4
10	Autoantibodies in the disease criteria for systemic sclerosis: The need for specification for optimal application Journal of Translational Autoimmunity ·Jan Damoiseaux,Judith Potjewijd,Ruben L. Smeets,Carolien Bonroy	2022	8
11	Diagnostic profiles for precision medicine in systemic sclerosis; stepping forward from single biomarkers towards pathophysiological panels Autoimmunity Reviews ·Ruben L. Smeets,Brigit E. Kersten,Irma Joosten,Charlotte Kaffa,Wynand Alkema,Hans J. P. M. Koenen,Madelon C Vonk	2020	19
12	Targeting PKC in Human T Cells Using Sotrastaurin (AEB071) Preserves Regulatory T Cells and Prevents IL-17 Production Journal of Investigative Dermatology ·Xuehui He,Hans J. P. M. Koenen,Ruben L. Smeets,R.R.M.C. Keijsers,Esther van Rijssen,Andreas Koerber,P C van de Kerkhof,Annemieke M. H. Boots,Irma Joosten	2013	33
13	Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling BMC Immunology ·Ruben L. Smeets,Wilco Fleuren,Xuehui He,Paul Vink,Frank Wijnands,Monika Górecka,Henri Klop,Sussane Bauerschmidt,Anja Garritsen,Hans J. P. M. Koenen,Irma Joosten,Annemieke M. H. Boots,Wynand Alkema	2012	39
14	Structure-based lead identification of ATP-competitive MK2 inhibitors Bioorganic & Medicinal Chemistry Letters ·Tjeerd Barf,Allard Kaptein,Sander de Wilde,Ruud van der Heijden,Richard van Someren,Dennis Demont,Carsten Schultz‐Fademrecht,Judith Versteegh,Mario van Zeeland,Nicole Seegers,Bert Kazemier,Bas van de Kar,Maaike van Hoek,Jeroen de Roos,Henri Klop,Ruben L. Smeets,Claudia L. Hofstra,Jorrit J. Hornberg,Arthur Oubrie	2011	19
15	A novel role for suppressor of cytokine signaling 3 in cartilage destruction via induction of chondrocyte desensitization toward insulin‐like growth factor Arthritis & Rheumatism ·Ruben L. Smeets,Sharon Veenbergen,Onno J. Arntz,M.B. Bennink,Leo A. B. Joosten,Wim B. van den Berg,Fons A. J. van de Loo	2006	41
16	Inhibition of TNFα during maturation of dendritic cells results in the development of semi-mature cells: a potential mechanism for the beneficial effects of TNFα blockade in rheumatoid arthritis Annals of the Rheumatic Diseases ·Antoine W.T. van Lieshout,Pilar Barrera,Ruben L. Smeets,G. J. Pesman,Piet L. C. M. van Riel,Wim B. van den Berg,Timothy R. D. J. Radstake	2004	45
17	Crucial role of synovial lining macrophages in the promotion of transforming growth factor β–mediated osteophyte formation Arthritis & Rheumatism ·Peter L. E. M. van Lent,Arjen B. Blom,P. van der Kraan,A. E. M. Holthuysen,E.L. Vitters,Nico van Rooijen,Ruben L. Smeets,Karin C. Nabbe,Wim B. van den Berg	2004	153
18	Toll-Like Receptor 2 Pathway Drives Streptococcal Cell Wall-Induced Joint Inflammation: Critical Role of Myeloid Differentiation Factor 88 The Journal of Immunology ·Leo A. B. Joosten,Marije I. Koenders,Ruben L. Smeets,Marleen Heuvelmans‐Jacobs,Monique M. Helsen,Kiyoshi Takeda,Shizuo Akira,Erik Lubberts,Fons A. J. van de Loo,Wim B. van den Berg	2003	181
19	Adenoviral delivery of IL-18 binding protein C ameliorates Collagen-Induced Arthritis in mice Gene Therapy ·Ruben L. Smeets,Fons A. J. van de Loo,Onno J. Arntz,M.B. Bennink,Leo A. B. Joosten,Wim B. van den Berg	2003	71
20	Effectiveness of the soluble form of the interleukin‐1 receptor accessory protein as an inhibitor of interleukin‐1 in collagen‐induced arthritis Arthritis & Rheumatism ·Ruben L. Smeets,Fons A. J. van de Loo,Leo A. B. Joosten,Onno J. Arntz,M.B. Bennink,W. A. Loesberg,Igor P. Dmitriev,David T. Curiel,Myriam Martin,Wim B. van den Berg	2003	39

About Ruben L. Smeets

Ruben L. Smeets is a scholar working on Immunology, Pathology and Forensic Medicine and Transplantation, having authored 46 papers that have together received 2.0k indexed citations. Recurring topics across this work include T-cell and B-cell Immunology (7 papers), Immune Cell Function and Interaction (6 papers), Immune Response and Inflammation (6 papers), interferon and immune responses (5 papers), Immunotherapy and Immune Responses (5 papers), Psoriasis: Treatment and Pathogenesis (5 papers), Systemic Sclerosis and Related Diseases (5 papers) and Cancer Immunotherapy and Biomarkers (4 papers). The work is most often cited by research in Immunology (1.1k citations), Rheumatology (434 citations) and Oncology (365 citations). Ruben L. Smeets has collaborated with scholars based in Netherlands, Germany and United States. Frequent co-authors include Hans J. P. M. Koenen, Irma Joosten, Annemieke M. H. Boots, Paul Vink, Esther van Rijssen, Wim B. van den Berg, Leo A. B. Joosten, Fons A. J. van de Loo, Onno J. Arntz and Marije I. Koenders. Their work appears in journals such as New England Journal of Medicine, Blood and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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