Ron R. Kopito

27.7k total citations · 11 hit papers
136 papers, 22.6k citations indexed

About

Ron R. Kopito is a scholar working on Molecular Biology, Cell Biology and Physiology. According to data from OpenAlex, Ron R. Kopito has authored 136 papers receiving a total of 22.6k indexed citations (citations by other indexed papers that have themselves been cited), including 97 papers in Molecular Biology, 43 papers in Cell Biology and 30 papers in Physiology. Recurrent topics in Ron R. Kopito's work include Ubiquitin and proteasome pathways (38 papers), Endoplasmic Reticulum Stress and Disease (29 papers) and Genetic Neurodegenerative Diseases (22 papers). Ron R. Kopito is often cited by papers focused on Ubiquitin and proteasome pathways (38 papers), Endoplasmic Reticulum Stress and Disease (29 papers) and Genetic Neurodegenerative Diseases (22 papers). Ron R. Kopito collaborates with scholars based in United States, United Kingdom and France. Ron R. Kopito's co-authors include Cristina L. Ward, Jennifer Johnston, Neil Bence, Harvey F. Lodish, Satoshi ŌMURA, John C. Christianson, Judith Frydman, James A. Olzmann, Ronald Melki and Thomas A. Shaler and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Ron R. Kopito

135 papers receiving 22.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Aggresomes: A Cellular Response to Misfolded Proteins

1998 1.8k citations Cristina L. Ward, Ron R. Kopito et al. The Journal of Cell Biology profile →
Impairment of the Ubiquitin-Proteasome System by Protein Aggregation

2001 1.8k citations Neil Bence, Ron R. Kopito et al. profile →
Aggresomes, inclusion bodies and protein aggregation

2000 1.6k citations Ron R. Kopito profile →
Degradation of CFTR by the ubiquitin-proteasome pathway

1995 1.1k citations Cristina L. Ward, Ron R. Kopito et al. Cell profile →
Misfolded proteins partition between two distinct quality control compartments

2008 747 citations Daniel Kaganovich, Ron R. Kopito et al. Nature profile →
Subversion of Cellular Autophagosomal Machinery by RNA Viruses

2005 668 citations Ron R. Kopito et al. profile →
Prion-like transmission of protein aggregates in neurodegenerative diseases

2010 593 citations Ron R. Kopito et al. profile →
HDAC6 and Microtubules Are Required for Autophagic Degradation of Aggregated Huntingtin

2005 587 citations Atsushi Iwata, Brigit E. Riley et al. Journal of Biological Chemistry profile →
Protein misfolding in neurodegenerative diseases: implications and strategies

2017 462 citations Judith Frydman, Ron R. Kopito et al. profile →
Primary structure and transmembrane orientation of the murine anion exchange protein

1985 450 citations Ron R. Kopito et al. Nature profile →
Glycerol Reverses the Misfolding Phenotype of the Most Common Cystic Fibrosis Mutation

1996 439 citations Sachiko Sato, Cristina L. Ward et al. Journal of Biological Chemistry profile →

Peers

Countries citing papers authored by Ron R. Kopito

Since Specialization

Citations

This map shows the geographic impact of Ron R. Kopito's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ron R. Kopito with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ron R. Kopito more than expected).

Fields of papers citing papers by Ron R. Kopito

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ron R. Kopito. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ron R. Kopito. The network helps show where Ron R. Kopito may publish in the future.

Co-authorship network of co-authors of Ron R. Kopito

This figure shows the co-authorship network connecting the top 25 collaborators of Ron R. Kopito. A scholar is included among the top collaborators of Ron R. Kopito based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ron R. Kopito. Ron R. Kopito is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	UFMylation orchestrates spatiotemporal coordination of RQC at the ER 2025 ·Science Advances ·(unknown), (unknown), (unknown), Otto Berninghausen, Thomas Becker, Ron R. Kopito, Roland Beckmann	3
2	Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways 2024 ·Proceedings of the National Academy of Sciences ·Kelsey Hickey, Alexandra Panov, (unknown), (unknown), Arda Mizrak, Ron R. Kopito, Wolfgang Baumeister, Rubén Fernández‐Busnadiego, J. Wade Harper	1
3	RPL26/uL24 UFMylation is essential for ribosome-associated quality control at the endoplasmic reticulum 2023 ·Proceedings of the National Academy of Sciences ·(unknown), (unknown), (unknown), Ron R. Kopito	38
4	Ribosomal protein RPL26 is the principal target of UFMylation 2019 ·Proceedings of the National Academy of Sciences ·Christopher P. Walczak, Dara E. Leto, Lichao Zhang, Celeste Riepe, Ryan Muller, Paul A. DaRosa, Nicholas T. Ingolia, Joshua E. Elias, Ron R. Kopito	130
5	Ubiquitin Accumulation on Disease Associated Protein Aggregates Is Correlated with Nuclear Ubiquitin Depletion, Histone De-Ubiquitination and Impaired DNA Damage Response 2017 ·PLoS ONE ·(unknown), (unknown), Ofra Novoplansky, Kirill Bersuker, Ron R. Kopito, Michal Goldberg, Michael Brandeis	31
6	Indirect inhibition of 26S proteasome activity in a cellular model of Huntington’s disease 2012 ·The Journal of Cell Biology ·Mark S. Hipp, Chetan N. Patel, Kirill Bersuker, Brigit E. Riley, Stephen E. Kaiser, Thomas A. Shaler, Michael Brandeis, Ron R. Kopito	131
7	Unassembled CD147 is an endogenous endoplasmic reticulum–associated degradation substrate 2012 ·Molecular Biology of the Cell ·Ryan E. Tyler, Margaret M.P. Pearce, Thomas A. Shaler, James A. Olzmann, Ethan J. Greenblatt, Ron R. Kopito	74
8	ALIX Is a Lys63-Specific Polyubiquitin Binding Protein that Functions in Retrovirus Budding 2012 ·Developmental Cell ·Dara P. Dowlatshahi, Virginie Sandrin, Sandro Vivona, Thomas A. Shaler, Stephen E. Kaiser, Francesco Melandri, Wesley I. Sundquist, Ron R. Kopito	63
9	Altered testicular gene expression patterns in mice lacking the polyubiquitin gene Ubb 2011 ·Molecular Reproduction and Development ·Shamim A. Sinnar, Christopher Small, Ryan Evanoff, Laura G. Reinholdt, Michael D. Griswold, Ron R. Kopito, Kwon‐Yul Ryu	18
10	The polyubiquitin Ubc gene modulates histone H2A monoubiquitylation in the R6/2 mouse model of Huntington's disease 2008 ·Journal of Cellular and Molecular Medicine ·John S. Bett, Caroline Benn, Kwon‐Yul Ryu, Ron R. Kopito, Gillian P. Bates	15
11	Misfolded proteins partition between two distinct quality control compartments breakdown → 2008 ·Nature ·Daniel Kaganovich, Ron R. Kopito, Judith Frydman	747
12	The Mouse Polyubiquitin Gene Ubb Is Essential for Meiotic Progression 2007 ·Molecular and Cellular Biology ·Kwon‐Yul Ryu, Shamim A. Sinnar, Laura G. Reinholdt, Sergio Vaccari, Susan J. Hall, Manuel A. Garcia, Tatiana S. Zaitseva, Donna M. Bouley, Kim Boekelheide, Mary Ann Handel, Marco Conti, Ron R. Kopito	83
13	Intersecting pathways to neurodegeneration in Parkinson's disease: Effects of the pesticide rotenone on DJ-1, α-synuclein, and the ubiquitin–proteasome system 2006 ·Neurobiology of Disease ·Ranjita Betarbet, Rosa Canet-Aviles, Todd Sherer, Pier G. Mastroberardino, Chris McLendon, Jin-Ho Kim, (unknown), (unknown), Georgia Taylor, Neil Bence, Ron R. Kopito, Byoung Boo Seo, Takao Yagi, (unknown), Gary Klinefelter, Mark Cookson, J. Timothy Greenamyre	274
14	Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation 2005 ·Proceedings of the National Academy of Sciences ·Atsushi Iwata, John C. Christianson, Mirella Bucci, Lisa Ellerby, Nobuyuki Nukina, Lysia S. Forno, Ron R. Kopito	260
15	Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis 2002 ·Journal of Clinical Investigation ·Marina S. Gelman, Ron R. Kopito	12
16	Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis 2002 ·Journal of Clinical Investigation ·Marina S. Gelman, Ron R. Kopito	69
17	Immunocytochemical localization of vacuolar H+-ATPase and Cl−-HCO 3 − anion exchanger (erythrocyte band-3 protein) in avian osteoclasts: Effect of calcium-deficient diet on polar expression of the H+-ATPase pump 1996 ·Calcified Tissue International ·Bahar Bastani, F. Patrick Ross, Ron R. Kopito, Stephen L. Gluck	19
18	Glycerol Reverses the Misfolding Phenotype of the Most Common Cystic Fibrosis Mutation breakdown → 1996 ·Journal of Biological Chemistry ·Sachiko Sato, Cristina L. Ward, Mauri E. Krouse, Jeffrey J. Wine, Ron R. Kopito	439
19	High Level Expression, Partial Purification, and Functional Reconstitution of the Human AE1 Anion Exchanger in Saccharomycescerevisiae 1995 ·Journal of Biological Chemistry ·Israel Sekler, Ron R. Kopito, Joseph R. Casey	34
20	Conformational states of CFTR associated with channel gating: The role of ATP binding and hydrolysis 1995 ·Cell ·Kevin L. Gunderson, Ron R. Kopito	190

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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