Judith Frydman

21.5k total citations · 5 hit papers
157 papers, 15.8k citations indexed

About

Judith Frydman is a scholar working on Molecular Biology, Materials Chemistry and Cell Biology. According to data from OpenAlex, Judith Frydman has authored 157 papers receiving a total of 15.8k indexed citations (citations by other indexed papers that have themselves been cited), including 137 papers in Molecular Biology, 50 papers in Materials Chemistry and 27 papers in Cell Biology. Recurrent topics in Judith Frydman's work include Heat shock proteins research (85 papers), Enzyme Structure and Function (50 papers) and Protein Structure and Dynamics (48 papers). Judith Frydman is often cited by papers focused on Heat shock proteins research (85 papers), Enzyme Structure and Function (50 papers) and Protein Structure and Dynamics (48 papers). Judith Frydman collaborates with scholars based in United States, Germany and Switzerland. Judith Frydman's co-authors include Sebastian Pechmann, F. Ulrich Hartl, Daniel Kaganovich, Amie J. McClellan, Ron R. Kopito, Christoph Spiess, Raul Andino, Ron Geller, Elmar Nimmesgern and Véronique Albanèse and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Judith Frydman

155 papers receiving 15.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Folding of Newly Translated Proteins In Vivo: The Role of Molecular Chaperones

2001 935 citations Judith Frydman profile →
Misfolded proteins partition between two distinct quality control compartments

2008 747 citations Daniel Kaganovich, Judith Frydman et al. Nature profile →
Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

1994 565 citations Judith Frydman, F. Ulrich Hartl et al. Nature profile →
Protein misfolding in neurodegenerative diseases: implications and strategies

2017 462 citations Judith Frydman et al. profile →
Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging

2018 382 citations Dena S. Leeman, Katja Hebestreit et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Judith Frydman United States	68	12.9k	3.4k	2.5k	1.4k	1.3k	157	15.8k
Manajit Hayer‐Hartl Germany	53	15.6k 1.2×	3.5k 1.0×	3.6k 1.4×	1.6k 1.1×	1.6k 1.2×	98	18.1k
Jason E. Gestwicki United States	70	10.8k 0.8×	2.5k 0.8×	983 0.4×	1.1k 0.8×	1.1k 0.8×	226	14.8k
Matthias P. Mayer Germany	61	11.7k 0.9×	2.9k 0.8×	1.9k 0.7×	374 0.3×	1.6k 1.2×	137	13.8k
Len Neckers United States	85	19.4k 1.5×	3.0k 0.9×	1.5k 0.6×	931 0.7×	4.0k 3.0×	248	24.9k
Michael K. Rosen United States	70	18.4k 1.4×	5.6k 1.7×	1.4k 0.6×	1.1k 0.8×	1.9k 1.4×	142	23.6k
Laurence H. Pearl United Kingdom	76	18.0k 1.4×	2.2k 0.7×	2.7k 1.1×	396 0.3×	2.1k 1.6×	217	21.3k
Péter Tompa Hungary	64	19.9k 1.5×	3.4k 1.0×	4.9k 1.9×	1.0k 0.7×	769 0.6×	240	23.8k
A. Keith Dunker United States	75	22.6k 1.7×	2.8k 0.8×	6.2k 2.4×	884 0.6×	919 0.7×	163	26.8k
Harm H. Kampinga Netherlands	65	9.6k 0.7×	2.9k 0.9×	750 0.3×	1.4k 1.0×	796 0.6×	232	13.6k
Andreas Bracher Germany	47	8.2k 0.6×	2.3k 0.7×	1.4k 0.6×	505 0.4×	688 0.5×	100	10.1k

Countries citing papers authored by Judith Frydman

Since Specialization

Citations

This map shows the geographic impact of Judith Frydman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Judith Frydman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Judith Frydman more than expected).

Fields of papers citing papers by Judith Frydman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Judith Frydman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Judith Frydman. The network helps show where Judith Frydman may publish in the future.

Co-authorship network of co-authors of Judith Frydman

This figure shows the co-authorship network connecting the top 25 collaborators of Judith Frydman. A scholar is included among the top collaborators of Judith Frydman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Judith Frydman. Judith Frydman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chou, Ching‐Chieh, Ryan T. Vest, Miguel A. Prado, et al.. (2025). Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer’s disease. Nature Cell Biology. 27(4). 619–632. 10 indexed citations

Tilk, Susanne, Judith Frydman, Christina Curtis, & Dmitri A. Petrov. (2024). Cancers adapt to their mutational load by buffering protein misfolding stress. eLife. 12. 1 indexed citations

Rodriguez-Aliaga, Piere, Tomáš Majtner, Stefanie Böhm, et al.. (2024). In situ analysis reveals the TRiC duty cycle and PDCD5 as an open-state cofactor. Nature. 637(8047). 983–990. 4 indexed citations

Groh, Carina, Lena Krämer, Kevin C. Stein, et al.. (2023). The unfolded protein response of the endoplasmic reticulum supports mitochondrial biogenesis by buffering nonimported proteins. Molecular Biology of the Cell. 34(10). ar95–ar95. 8 indexed citations

Collier, M, Kathy H. Li, Yuchan Chen, et al.. (2021). Native mass spectrometry analyses of chaperonin complex TRiC/CCT reveal subunit N-terminal processing and re-association patterns. Scientific Reports. 11(1). 13084–13084. 9 indexed citations

Knowlton, Jonathan J., Daniel R. Gestaut, Boxue Ma, et al.. (2021). Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network. Proceedings of the National Academy of Sciences. 118(11). 28 indexed citations

Wu, Gong‐Her, Jesús G. Galaz-Montoya, Corey W. Hecksel, et al.. (2020). Multi-scale 3D Cryo-Correlative Microscopy for Vitrified Cells. Structure. 28(11). 1231–1237.e3. 48 indexed citations

Shen, Koning, Yulian Gavrilov, Pieter E. S. Smith, et al.. (2018). Huntingtin’s N-Terminus Rearrangements in the Presence of Membranes: A Joint Spectroscopic and Computational Perspective. ACS Chemical Neuroscience. 10(1). 472–481. 16 indexed citations

Leeman, Dena S., Katja Hebestreit, Ashley E. Webb, et al.. (2018). Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging. Science. 359(6381). 1277–1283. 382 indexed citations breakdown →

10.

Nayak, Arabinda, Dong Young Kim, Michael J. Trnka, et al.. (2018). A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability. Cell Host & Microbe. 24(4). 542–557.e9. 27 indexed citations

11.

Frydman, Judith, et al.. (2018). Post-extubation non-invasive ventilation in the pediatric intensive care unit: a multicenter study. Archivos Argentinos de Pediatria. 116(5). 333–339. 12 indexed citations

12.

Ogawa, N., Yohei Yamamoto, Keisuke Abé, et al.. (2018). Time-Resolved Measurement of the ATP-Dependent Motion of the Group II Chaperonin by Diffracted Electron Tracking. International Journal of Molecular Sciences. 19(4). 950–950. 2 indexed citations

13.

Frydman, Judith. (2018). Proteostasis Function and Disfunction: The Folding Machines that Maintain Proteome Health. Biophysical Journal. 114(3). 544a–545a. 1 indexed citations

14.

Shen, Koning, Barbara Calamini, Jonathan A. Fauerbach, et al.. (2016). Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract. eLife. 5. 53 indexed citations

15.

Frydman, Judith. (2012). Mechanism and Function of the Eukaryotic Ring-Shaped Chaperonin TRiC/CCT. Biophysical Journal. 102(3). 428a–428a. 1 indexed citations

16.

Cong, Yao, Matthew L. Baker, Joanita Jakana, et al.. (2010). 4.0-Å resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement. Proceedings of the National Academy of Sciences. 107(11). 4967–4972. 139 indexed citations

17.

Pan, Xuewen, Zhiwei Huang, Daniel Yuan, et al.. (2010). Trivalent Arsenic Inhibits the Functions of Chaperonin Complex. Genetics. 186(2). 725–734. 48 indexed citations

18.

McClellan, Amie J., Stephen J. Tam, Daniel Kaganovich, & Judith Frydman. (2005). Protein quality control: chaperones culling corrupt conformations. Nature Cell Biology. 7(8). 736–741. 226 indexed citations

19.

Meyer, Anne S., et al.. (2003). Closing the Folding Chamber of the Eukaryotic Chaperonin Requires the Transition State of ATP Hydrolysis. Cell. 113(3). 369–381. 166 indexed citations

20.

Frydman, Judith & F. Ulrich Hartl. (1994). 10 Molecular Chaperone Functions of hsp70 and hsp60 in Protein Folding. Cold Spring Harbor Monograph Archive. 26. 251–283. 34 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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