Richard J. Simpson

57.1k citations

558 papers · 42.5k indexed · 18 hit papers · h-index 91

Impact in

Cancer Research top 0.02%
- MicroRNA in disease regulation
Immunology and Allergy top 0.1%

Papers in

Immunology and Allergy 39
Spectroscopy 98
- Advanced Proteomics Techniques and Applications 74
- Mass Spectrometry Techniques and Applications 52
- Analytical Chemistry and Chromatography 28

Co-authors: Suresh Mathivanan Robert L. Moritz David W. Greening Hong Ji Gavin E. Reid Rong Xu Bow J. Tauro Alin Rai
Journals: Cold Spring Harbor Protocols (36 papers)Journal of Biological Chemistry (35 papers)Electrophoresis (24 papers)Proceedings of the National Academy of Sciences (23 papers)PROTEOMICS (23 papers)
Partner nations: Australia United States Belgium

In The Last Decade

Richard J. Simpson

547 papers receiving 41.4k citations

Hit Papers

15 papers align trajectories log scale

Extracellular vesicles in cancer — implications for future improvements in cancer care 2018 · 1.1k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2018 Nature Reviews Clinical Oncology
2016 Journal of Clinical Investigation
2015 PROTEOMICS
2015 Methods in molecular biology
2015 Seminars in Cell and Developmental Biology
2013 PROTEOMICS
2012 Methods
2011 Nucleic Acids Research
2010 Journal of Proteomics
2009 Expert Review of Proteomics
2009 PROTEOMICS
2008 PROTEOMICS
2000 Cell
1999 Proceedings of the National Academy of Sciences
1990 Proceedings of the National Academy of Sciences
1989 Nature
1987 The Journal of Experimental Medicine
1986 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Richard J. Simpson

Since Specialization

Citations

This map shows the geographic impact of Richard J. Simpson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Richard J. Simpson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Richard J. Simpson more than expected).

Fields of papers citing papers by Richard J. Simpson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Richard J. Simpson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Richard J. Simpson. The network helps show where Richard J. Simpson may publish in the future.

Co-authors

The 25 scholars most cited alongside Richard J. Simpson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Richard J. Simpson Line = papers co-authored together Richard J. Simpson links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Clinical relevance of extracellular vesicles in cancer — therapeutic and diagnostic potential Nature Reviews Clinical Oncology ·David W. Greening, Rong Xu, Alin Rai, Wittaya Suwakulsiri, Maoshan Chen, Richard J. Simpson	2025	3
2	Transcriptomic analysis and fusion gene identifications of midbody remnants released from colorectal cancer cells reveals they are molecularly distinct from exosomes and microparticles PROTEOMICS ·Wittaya Suwakulsiri, Rong Xu, Alin Rai, Maoshan Chen, Adnan Shafiq, David W. Greening, Richard J. Simpson	2024	4
3	Comparative proteomic analysis of three major extracellular vesicle classes secreted from human primary and metastatic colorectal cancer cells: Exosomes, microparticles, and shed midbody remnants PROTEOMICS ·Wittaya Suwakulsiri, Rong Xu, Alin Rai, Adnan Shafiq, Maoshan Chen, David W. Greening, Richard J. Simpson	2023	9
4	Secreted midbody remnants are a class of extracellular vesicles molecularly distinct from exosomes and microparticles Communications Biology ·Alin Rai, David W. Greening, Rong Xu, Maoshan Chen, Wittaya Suwakulsiri, Richard J. Simpson	2021	60
5	Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis Molecular Cancer Therapeutics ·Joy Gary, John K. Simmons, Jinfei Xu, Shuling Zhang, Tyler J. Peat, Nicholas Watson, Benjamin J. Gamache, Ke Zhang, Alexander L. Kovalchuk, Aleksandra M. Michalowski, Jin‐Qiu Chen, Tuddow Thaiwong, Matti Kiupel, Snehal Gaikwad, Maudeline Etienne, Richard J. Simpson, Wendy Dubois, Joseph R. Testa, Beverly A. Mock	2020	8
6	Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast‐Led Cancer Invasion PROTEOMICS ·Alin Rai, David W. Greening, Rong Xu, Wittaya Suwakulsiri, Richard J. Simpson	2020	25
7	The Outcome of TGFβ Antagonism in Metastatic Breast Cancer Models In Vivo Reflects a Complex Balance between Tumor-Suppressive and Proprogression Activities of TGFβ Clinical Cancer Research ·Yu-an Yang, Howard H. Yang, Binwu Tang, Alex Man Lai Wu, Kathleen C. Flanders, Nellie Moshkovich, Douglas S. Weinberg, Michael A. Welsh, Jia Weng, Humberto de Jesús Ochoa Domínguez, Tiffany Hu, Michelle A. Herrmann, Jinqiu Chen, Elijah F. Edmondson, Richard J. Simpson, Fang Liu, Huaitian Liu, Maxwell P. Lee, Lalage M. Wakefield	2019	20
8	Understanding extracellular vesicle diversity – current status Expert Review of Proteomics ·David W. Greening, Richard J. Simpson	2018	133
9	Ras enhances TGF-β signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1 Cell Communication and Signaling ·Sheng Liu, Josephine Iaria, Richard J. Simpson, Hong‐Jian Zhu	2018	14
10	Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor–Driven Lung Adenocarcinoma Cancer Discovery ·Tapan K. Maity, Abhilash Venugopalan, Ilona Linnoila, Constance M. Cultraro, Andreas Giannakou, Roxanne Nemati, Xu Zhang, Joshua D. Webster, Daniel A. Ritt, Sarani Ghosal, Heinz Hoschuetzky, Richard J. Simpson, Romi Biswas, Katerina Politi, Deborah K. Morrison, Harold Varmus, Udayan Guha	2015	51
11	The Protein Phosphatase 2A Inhibitor LB100 Sensitizes Ovarian Carcinoma Cells to Cisplatin-Mediated Cytotoxicity Molecular Cancer Therapeutics ·Ki-Eun Chang, Bih‐Rong Wei, James P. Madigan, Matthew D. Hall, Richard J. Simpson, Zhengping Zhuang, Michael M. Gottesman	2014	39
12	Deletion of the Proline-Rich Region of the Murine Metastasis Susceptibility Gene Brd4 Promotes Epithelial-to-Mesenchymal Transition- and Stem Cell-Like Conversion Cancer Research ·Jude Alsarraj, Renard C. Walker, Joshua D. Webster, Thomas R. Geiger, Nigel P.S. Crawford, Richard J. Simpson, Keiko Ozato, Kent W. Hunter	2011	56
13	Serum/Plasma Proteomics Methods in molecular biology ·Richard J. Simpson, David W. Greening	2011	12
14	Basic methods in protein purification and analysis : a laboratory manual Richard J. Simpson, Peter D. Adams, Erica A. Golemis	2009	10
15	Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/Friend of GATA interaction Proceedings of the National Academy of Sciences ·Chu Kong Liew, Richard J. Simpson, Ann H. Kwan, Linda Crofts, Fionna E. Loughlin, Jacqueline M. Matthews, Merlin Crossley, Joel P. Mackay	2005	82
16	Treatment of ras-induced cancers by the F-actin-bundling drug MKT-077. PubMed ·Anjali Tikoo, Rushdi Shakri, Lisa Connolly, Yasuko Hirokawa, Takayuki Shishido, Bill Bowers, Lihong Ye, Kazuhiro Kohama, Richard J. Simpson, Hiroshi Maruta	2000	20
17	HIGH-SPEED CHROMATOGRAPHIC-SEPARATION OF PROTEINS AND PEPTIDES - APPLICATION TO RAPID PEPTIDE-MAPPING OF IN-GEL DIGESTED PROTEINS Journal of Protein Chemistry ·Moritz Rl, James S. Eddes, Harris Ji, Gavin E. Reid, Richard J. Simpson	1994	1
18	Characterization of bovine heparin-binding neurotrophic factor (HBNF): assignment of disulfide bonds. PubMed ·Louis Fabri, Nice Ec, Ward Ld, Hiroshi Maruta, AW Burgess, Richard J. Simpson	1992	11
19	αB Crystallin Accumulation Is a Specific Response to Ha- ras and v- mos Oncogene Expression in Mouse NIH 3T3 Fibroblasts Molecular and Cellular Biology ·R Klemenz, Erika Fröhli, Akira Aoyama, Sylvia Hoffmann, Richard J. Simpson, Robert L. Moritz, Reinhold Schäfer	1991	91
20	Occurrence of fructans in the Gramineae (Poaceae) New Phytologist ·HENK SMOUTER, Richard J. Simpson	1989	43

About Richard J. Simpson

Richard J. Simpson is a scholar working on Immunology and Allergy, Spectroscopy, Molecular Biology, Immunology and Cancer Research, having authored 558 papers that have together received 42.5k indexed citations. Recurring topics across this work include Advanced Proteomics Techniques and Applications (74 papers), Glycosylation and Glycoproteins Research (59 papers), Mass Spectrometry Techniques and Applications (52 papers), Extracellular vesicles in disease (52 papers), Monoclonal and Polyclonal Antibodies Research (47 papers), Analytical Chemistry and Chromatography (28 papers), MicroRNA in disease regulation (27 papers) and Cytokine Signaling Pathways and Interactions (27 papers). The work is most often cited by research in Cancer Research (9.4k citations), Immunology and Allergy (2.8k citations), Molecular Biology (27.6k citations), Immunology (7.4k citations) and Oncology (5.2k citations). Richard J. Simpson has collaborated with scholars based in Australia, United States and Belgium. Frequent co-authors include Suresh Mathivanan, Robert L. Moritz, David W. Greening, Hong Ji, Gavin E. Reid, Rong Xu, Bow J. Tauro, Alin Rai, Lisa Connolly and Justin Lim. Their work appears in journals such as Cold Spring Harbor Protocols, Journal of Biological Chemistry, Electrophoresis, Proceedings of the National Academy of Sciences and PROTEOMICS.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact