Sandra E. Nicholson

9.6k citations

90 papers · 6.7k indexed · 2 hit papers · h-index 41

Impact in

Immunology top 0.5%
- interferon and immune responses
- Immune Cell Function and Interaction
- Immune Response and Inflammation
Oncology top 0.5%
- Cytokine Signaling Pathways and Interactions

Papers in ⓘ

Oncology 53
- Cytokine Signaling Pathways and Interactions 51
Immunology 51
- interferon and immune responses 25
- Immune Cell Function and Interaction 12
- Immune Response and Inflammation 12
- T-cell and B-cell Immunology 8

Co-authors: Hiu Kiu (2 shared papers)Douglas J. Hilton (14 shared papers)Nicos A. Nicola (24 shared papers)Tracy A. Willson (13 shared papers)Ben A. Croker (2 shared papers)Donald Metcalf (8 shared papers)Edmond M. Linossi (12 shared papers)Warren S. Alexander (14 shared papers)
Journals: Proceedings of the National Academy of Sciences (6 papers)Journal of Biological Chemistry (5 papers)Cytokine (5 papers)Growth Factors (5 papers)Immunology and Cell Biology (4 papers)
Partner nations: Australia United Kingdom United States

In The Last Decade

Sandra E. Nicholson

89 papers receiving 6.6k citations

Hit Papers

align trajectories log scale

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation 1999 · 530 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1999 Proceedings of the National Academy of Sciences
1998 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Sandra E. Nicholson

Since Specialization

Citations

This map shows the geographic impact of Sandra E. Nicholson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sandra E. Nicholson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sandra E. Nicholson more than expected).

Fields of papers citing papers by Sandra E. Nicholson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sandra E. Nicholson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sandra E. Nicholson. The network helps show where Sandra E. Nicholson may publish in the future.

Co-authors

The 25 scholars most cited alongside Sandra E. Nicholson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Sandra E. Nicholson Line = papers co-authored together Sandra E. Nicholson links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 90 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Twenty proteins containing a C-terminal SOCS box form five structural classes Proceedings of the National Academy of Sciences ·Douglas J. Hilton, Rachael T. Richardson, Warren S. Alexander, Elizabeth M. Viney, Tracy A. Willson, Naomi S. Sprigg, Robyn Starr, Sandra E. Nicholson, Donald Metcalf, Nicos A. Nicola Hit paper breakdown →	1998	638
2	The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation Proceedings of the National Academy of Sciences ·Jian‐Guo Zhang, Alison Farley, Sandra E. Nicholson, Tracy A. Willson, Lisa M. Zugaro, Richard J. Simpson, Robert L. Moritz, Dale Cary, Rachael T. Richardson, George Hausmann, Benjamin T. Kile, Stephen B. H. Kent, Warren S. Alexander, Donald Metcalf, Douglas J. Hilton, Nicos A. Nicola, Manuel Baca Hit paper breakdown →	1999	530
3	SOCS regulation of the JAK/STAT signalling pathway Seminars in Cell and Developmental Biology ·Ben A. Croker, Hiu Kiu, Sandra E. Nicholson	2008	496
4	Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation Nature Immunology ·Ashley Mansell, Rosealee Smith, Sarah Doyle, Pearl Gray, Jennifer E Fenner, Peter J. Crack, Sandra E. Nicholson, Douglas J. Hilton, Luke O'neill, Paul J. Hertzog	2006	434
5	Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130 Proceedings of the National Academy of Sciences ·Sandra E. Nicholson, David P. De Souza, Louis Fabri, Jason Corbin, Tracy A. Willson, Jian‐Guo Zhang, Anabel Silva, Maria Asimakis, Alison Farley, Andrew D. Nash, Donald Metcalf, Douglas J. Hilton, Nicos A. Nicola, Manuel Baca	2000	395
6	Biology and significance of the JAK/STAT signalling pathways Growth Factors ·Hiu Kiu, Sandra E. Nicholson	2012	360
7	Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction The EMBO Journal ·Sandra E. Nicholson	1999	355
8	Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation. Proceedings of the National Academy of Sciences ·Sandra E. Nicholson, Andrew C. Oates, Ailsa G. Harpur, Andrew Ziemiecki, Andrew F. Wilks, Judith E. Layton	1994	175
9	Time is the enemy: Mortality in trauma patients with hemorrhage from torso injury occurs long before the “golden hour” The American Journal of Surgery ·Abdul Q. Alarhayem, John G. Myers, Daniel L. Dent, Lillian Liao, Mark T. Muir, Deborah Mueller, Sandra E. Nicholson, Ramón F. Cestero, Michael Johnson, Ronald M. Stewart, Grant E. O’Keefe, Brian J. Eastridge	2016	161
10	Suppression of cytokine signaling: The SOCS perspective Cytokine & Growth Factor Reviews ·Edmond M. Linossi, Jeffrey J. Babon, Douglas J. Hilton, Sandra E. Nicholson	2013	146
11	The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability Molecular Cell ·Jeffrey J. Babon, Edward J. McManus, Shenggen Yao, David P. De Souza, Lisa A. Mielke, Naomi S. Sprigg, Tracy A. Willson, Douglas J. Hilton, Nicos A. Nicola, Manuel Baca, Sandra E. Nicholson, Raymond S. Norton	2006	134
12	Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells Nature Communications ·Priyanka Sathe, Rebecca B. Delconte, Fernando Souza-Fonseca-Guimarães, Cyril Seillet, Michaël Chopin, Cassandra J. Vandenberg, Lucille C. Rankin, Lisa A. Mielke, Ingela B. Vikstrom, Tatiana B. Kolesnik, Sandra E. Nicholson, Éric Vivier, Mark J. Smyth, Stephen L. Nutt, Stefan Glaser, Andreas Strasser, Gabrielle T. Belz, Sebastian Carotta, Nicholas D. Huntington	2014	131
13	The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo Proceedings of the National Academy of Sciences ·Jian‐Guo Zhang, Donald Metcalf, Steven Rakar, Maria Asimakis, Christopher J. Greenhalgh, Tracy A. Willson, Robyn Starr, Sandra E. Nicholson, Wendy Carter, Warren S. Alexander, Douglas J. Hilton, Nicos A. Nicola	2001	128
14	SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation Molecular and Cellular Biology ·Danielle L. Krebs, Rachel T. Uren, Donald Metcalf, Steven Rakar, Jian‐Guo Zhang, Robyn Starr, David P. De Souza, Kathy Hanzinikolas, Jo Eyles, Lisa Connolly, Richard J. Simpson, Nicos A. Nicola, Sandra E. Nicholson, Manuel Baca, Douglas J. Hilton, Warren S. Alexander	2002	128
15	Suppressor of Cytokine Signaling (SOCS) 1 Inhibits Type I Interferon (IFN) Signaling via the Interferon α Receptor (IFNAR1)-associated Tyrosine Kinase Tyk2 Journal of Biological Chemistry ·Rebecca Piganis, Nicole A. de Weerd, Jodee A. Gould, Christian Schindler, Ashley Mansell, Sandra E. Nicholson, Paul J. Hertzog	2011	125
16	Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity Protein Science ·Akshay A. D’Cruz, Jeffrey J. Babon, Raymond S. Norton, Nicos A. Nicola, Sandra E. Nicholson	2012	111
17	The SOCS proteins: a new family of negative regulators of signal transduction Journal of Leukocyte Biology ·Sandra E. Nicholson, Douglas J. Hilton	1998	111
18	The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development Development ·Walid T. Khaled, Eliot Read, Sandra E. Nicholson, Fiona O. Baxter, A. J. Brennan, Paul J. Came, Naomi S. Sprigg, Andrew N. J. McKenzie, Christine J. Watson	2007	102
19	The SOCS box—Adapting proteins for ubiquitination and proteasomal degradation IUBMB Life ·Edmond M. Linossi, Sandra E. Nicholson	2012	98
20	DNAM-1 Expression Marks an Alternative Program of NK Cell Maturation Cell Reports ·Ludovic Martinet, Lucas Ferrari de Andrade, Camille Guillerey, Jason S. Lee, Jing Liu, Fernando Souza-Fonseca-Guimarães, Dana S. Hutchinson, Tatiana B. Kolesnik, Sandra E. Nicholson, Nicholas D. Huntington, Mark J. Smyth	2015	97

About Sandra E. Nicholson

Sandra E. Nicholson is a scholar working on Oncology, Immunology, Molecular Biology, Pharmacology and Cancer Research, having authored 90 papers that have together received 6.7k indexed citations. Recurring topics across this work include Cytokine Signaling Pathways and Interactions (51 papers), interferon and immune responses (25 papers), Immune Cell Function and Interaction (12 papers), Medicinal Plant Pharmacodynamics Research (12 papers), Immune Response and Inflammation (12 papers), NF-κB Signaling Pathways (9 papers), T-cell and B-cell Immunology (8 papers) and Protein Kinase Regulation and GTPase Signaling (6 papers). The work is most often cited by research in Immunology (3.4k citations), Oncology (3.5k citations), Pharmacology (710 citations), Cancer Research (816 citations) and Molecular Biology (2.4k citations). Sandra E. Nicholson has collaborated with scholars based in Australia, United Kingdom and United States. Frequent co-authors include Hiu Kiu, Douglas J. Hilton, Nicos A. Nicola, Tracy A. Willson, Ben A. Croker, Donald Metcalf, Edmond M. Linossi, Warren S. Alexander, Jian‐Guo Zhang and Robyn Starr. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, Cytokine, Growth Factors and Immunology and Cell Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact