Ghislain Opdenakker

38.9k total citations · 8 hit papers
512 papers, 30.1k citations indexed

About

Ghislain Opdenakker is a scholar working on Cancer Research, Molecular Biology and Immunology. According to data from OpenAlex, Ghislain Opdenakker has authored 512 papers receiving a total of 30.1k indexed citations (citations by other indexed papers that have themselves been cited), including 187 papers in Cancer Research, 163 papers in Molecular Biology and 163 papers in Immunology. Recurrent topics in Ghislain Opdenakker's work include Protease and Inhibitor Mechanisms (177 papers), Cell Adhesion Molecules Research (99 papers) and Chemokine receptors and signaling (79 papers). Ghislain Opdenakker is often cited by papers focused on Protease and Inhibitor Mechanisms (177 papers), Cell Adhesion Molecules Research (99 papers) and Chemokine receptors and signaling (79 papers). Ghislain Opdenakker collaborates with scholars based in Belgium, Saudi Arabia and United Kingdom. Ghislain Opdenakker's co-authors include Jo Van Damme, Philippe E. Van den Steen, Paul Proost, Sofie Struyf, Pauline M. Rudd, Alfons Billiau, Raymond A. Dwek, Jennifer Vandooren, Stefan Masure and Anja Wuyts and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Ghislain Opdenakker

506 papers receiving 29.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Biochemistry and Molecular Biology of Gelatinase B or Matrix Metalloproteinase-9 (MMP-9)

2002 789 citations Philippe E. Van den Steen, Ghislain Opdenakker et al. Critical Reviews in Biochemistry and Molecular Biology profile →
Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases

2007 634 citations Jialiang Hu, Philippe E. Van den Steen et al. profile →
Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade

2013 619 citations Jennifer Vandooren, Philippe E. Van den Steen et al. Critical Reviews in Biochemistry and Molecular Biology profile →
Concepts and Principles of O-Linked Glycosylation

1998 600 citations Philippe E. Van den Steen, Ghislain Opdenakker et al. Critical Reviews in Biochemistry and Molecular Biology profile →
Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 598 citations Jo Van Damme, Ghislain Opdenakker et al. The Journal of Experimental Medicine profile →
Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-α and leaves RANTES and MCP-2 intact

2000 564 citations Philippe E. Van den Steen, Paul Proost et al. Blood profile →
Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

2015 462 citations Ghislain Opdenakker et al. profile →
Matrix metalloproteinases in arthritis: towards precision medicine

2023 110 citations Bernard Grillet, Jo Van Damme et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ghislain Opdenakker Belgium	91	9.5k	9.4k	8.6k	8.0k	3.4k	512	30.1k
Jo Van Damme Belgium	108	12.7k 1.3×	16.7k 1.8×	13.7k 1.6×	4.4k 0.6×	4.2k 1.2×	547	41.8k
Harold A. Chapman United States	83	7.9k 0.8×	4.8k 0.5×	3.6k 0.4×	7.0k 0.9×	3.1k 0.9×	163	23.6k
Jacques J. Peschon United States	63	9.1k 1.0×	11.5k 1.2×	5.9k 0.7×	3.2k 0.4×	2.3k 0.7×	94	24.8k
Dylan R. Edwards United Kingdom	82	9.5k 1.0×	2.8k 0.3×	6.2k 0.7×	9.1k 1.1×	2.9k 0.9×	233	22.9k
Francisco Sánchez‐Madrid Spain	99	16.7k 1.8×	16.7k 1.8×	5.5k 0.6×	6.4k 0.8×	10.3k 3.0×	525	39.9k
Jordan S. Pober United States	97	12.0k 1.3×	15.7k 1.7×	4.3k 0.5×	4.7k 0.6×	6.3k 1.8×	362	37.0k
Yasunori Okada Japan	94	11.6k 1.2×	3.5k 0.4×	9.0k 1.0×	12.3k 1.5×	4.3k 1.3×	602	33.0k
Naofumi Mukaida Japan	89	7.3k 0.8×	12.5k 1.3×	7.8k 0.9×	3.6k 0.4×	1.8k 0.5×	376	28.4k
Ann M. Dvořàk United States	87	13.7k 1.4×	8.4k 0.9×	4.1k 0.5×	4.4k 0.6×	4.8k 1.4×	330	30.5k
Brian Seed United States	77	17.8k 1.9×	11.8k 1.2×	5.0k 0.6×	3.8k 0.5×	5.2k 1.5×	155	33.2k

Countries citing papers authored by Ghislain Opdenakker

Since Specialization

Citations

This map shows the geographic impact of Ghislain Opdenakker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ghislain Opdenakker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ghislain Opdenakker more than expected).

Fields of papers citing papers by Ghislain Opdenakker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ghislain Opdenakker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ghislain Opdenakker. The network helps show where Ghislain Opdenakker may publish in the future.

Co-authorship network of co-authors of Ghislain Opdenakker

This figure shows the co-authorship network connecting the top 25 collaborators of Ghislain Opdenakker. A scholar is included among the top collaborators of Ghislain Opdenakker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ghislain Opdenakker. Ghislain Opdenakker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Metzemaekers, Mieke, Bert Malengier‐Devlies, Mieke Gouwy, et al.. (2023). Fast and furious: The neutrophil and its armamentarium in health and disease. Medicinal Research Reviews. 43(5). 1537–1606. 16 indexed citations

Opdenakker, Ghislain, Norma Uribe‐Uribe, Diana Aguilar‐León, et al.. (2022). Autoantigen characterization in the lower esophageal sphincter muscle of patients with achalasia. Neurogastroenterology & Motility. 34(9). e14348–e14348. 6 indexed citations

Ugarte-Berzal, Estefanía, Erik Martens, Olivia Cano‐Garrido, et al.. (2020). Recombinant Protein-Based Nanoparticles: Elucidating Their Inflammatory Effects In Vivo and Their Potential as a New Therapeutic Format. Pharmaceutics. 12(5). 450–450. 7 indexed citations

Vandermosten, Leen, Thao‐Thy Pham, Julie Deckers, et al.. (2018). Experimental malaria-associated acute respiratory distress syndrome is dependent on the parasite-host combination and coincides with normocyte invasion. Malaria Journal. 17(1). 102–102. 27 indexed citations

Vandooren, Jennifer, Ghislain Opdenakker, Paul M. Loadman, & Dylan R. Edwards. (2016). Proteases in cancer drug delivery. Advanced Drug Delivery Reviews. 97. 144–155. 89 indexed citations

Grünwald, Barbara T., Jennifer Vandooren, Michael Gerg, et al.. (2016). Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow. Molecular Cancer Research. 14(11). 1147–1158. 47 indexed citations

Liekens, Sandra, Annelies Bronckaers, Mirella Belleri, et al.. (2012). The Thymidine Phosphorylase Inhibitor 5′- O -Tritylinosine (KIN59) Is an Antiangiogenic Multitarget Fibroblast Growth Factor-2 Antagonist. Molecular Cancer Therapeutics. 11(4). 817–829. 20 indexed citations

Berghmans, Nele, et al.. (2011). Interferon-γ Orchestrates the Number and Function of Th17 Cells in Experimental Autoimmune Encephalomyelitis. Journal of Interferon & Cytokine Research. 31(7). 575–587. 18 indexed citations

Steen, Philippe E. Van den, Nathalie Geurts, Katrien Deroost, et al.. (2010). Immunopathology and Dexamethasone Therapy in a New Model for Malaria-associated Acute Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine. 181(9). 957–968. 98 indexed citations

10.

Cauwe, Bénédicte & Ghislain Opdenakker. (2010). Intracellular substrate cleavage: a novel dimension in the biochemistry, biology and pathology of matrix metalloproteinases. Critical Reviews in Biochemistry and Molecular Biology. 45(5). 351–423. 238 indexed citations

11.

Piccard, Heléne, Jialiang Hu, Pierre Fiten, et al.. (2009). “Reverse degradomics”, monitoring of proteolytic trimming by multi‐CE and confocal detection of fluorescent substrates and reaction products. Electrophoresis. 30(13). 2366–2377. 11 indexed citations

12.

Proost, Paul, Tamara Loos, Anneleen Mortier, et al.. (2008). Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation. The Journal of Experimental Medicine. 205(9). 2085–2097. 149 indexed citations

13.

Andreï, Graciela, Don B. Gammon, Pierre Fiten, et al.. (2006). Cidofovir Resistance in Vaccinia Virus Is Linked to Diminished Virulencein Mice. Journal of Virology. 80(19). 9391–9401. 70 indexed citations

14.

Loos, Tamara, Sofie Struyf, Evemie Schutyser, et al.. (2006). TLR ligands and cytokines induce CXCR3 ligands in endothelial cells: enhanced CXCL9 in autoimmune arthritis. Laboratory Investigation. 86(9). 902–916. 101 indexed citations

15.

Velders, Gerjo A., Ronald van Os, H. F. L. Guiot, et al.. (2003). Reduced stem cell mobilization in mice receiving antibiotic modulation of the intestinal flora: involvement of endotoxins as cofactors in mobilization. Blood. 103(1). 340–346. 43 indexed citations

16.

Casciano, Ida, Rosella Muresu, Emanuela V. Volpi, et al.. (1996). Molecular and genetic studies on the region of translocation and duplication in the neuroblastoma cell line NGP at the 1p36.13-p36.32 chromosomal site.. Oxford University Research Archive (ORA) (University of Oxford). 12(10). 2101–8. 11 indexed citations

17.

Masure, Stefan, Liesbet Paemen, Paul Proost, Jo Van Damme, & Ghislain Opdenakker. (1995). Expression of a Human Mutant Monocyte Chemotactic Protein 3 in Pichia pastoris and Characterization as an MCP-3 Receptor Antagonist. Journal of Interferon & Cytokine Research. 15(11). 955–963. 23 indexed citations

18.

Laureys, Geneviève, Rogier Versteeg, Frank Speleman, et al.. (1995). Characterisation of the chromosome breakpoints in a patient with a constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12) and neuroblastoma. European Journal of Cancer. 31(4). 523–526. 13 indexed citations

19.

Opdenakker, Ghislain, Pierre Fiten, Guy Froyen, et al.. (1994). The Human MCP-3 Gene (SCYA7): Cloning, Sequence Analysis, and Assignment to the C-C Chemokine Gene Cluster on Chromosome 17q11.2-q12. Genomics. 21(2). 403–408. 31 indexed citations

20.

Opdenakker, Ghislain, Stefan Masure, Paul Proost, Alfons Billiau, & Jo Van Damme. (1991). Natural human monocyte gelatinase and its inhibitor. FEBS Letters. 284(1). 73–78. 46 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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