Randy J. Chandler

3.2k citations

48 papers · 2.0k indexed · 1 hit paper · h-index 26

Co-authors: Charles P. Venditti Nuria Carrillo Mark S. Sands Victoria Hoffmann Shawn M. Burgess Gaurav K. Varshney Matthew C. LaFave Julien S. Senac
Topics: Virus-based gene therapy research (24 papers)Metabolism and Genetic Disorders (20 papers)CRISPR and Genetic Engineering (11 papers)
Cited by: Clinical Biochemistry Genetics Molecular Biology
Journals: The Lancet Journal of Clinical Investigation Blood
Partner nations: United States Italy Australia

In The Last Decade

Randy J. Chandler

47 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evaluating the state of the science for adeno-associated virus integration: An integrated perspective

2022 128 citations Denise E. Sabatino, Frederic D. Bushman et al. Molecular Therapy profile →

Peers

Countries citing papers authored by Randy J. Chandler

Since Specialization

Citations

This map shows the geographic impact of Randy J. Chandler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Randy J. Chandler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Randy J. Chandler more than expected).

Fields of papers citing papers by Randy J. Chandler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Randy J. Chandler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Randy J. Chandler. The network helps show where Randy J. Chandler may publish in the future.

Co-authorship network of co-authors of Randy J. Chandler

This figure shows the co-authorship network connecting the top 25 collaborators of Randy J. Chandler. A scholar is included among the top collaborators of Randy J. Chandler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Randy J. Chandler. Randy J. Chandler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Growth advantage of corrected hepatocytes in a juvenile model of methylmalonic acidemia following liver directed adeno-associated viral mediated nuclease-free genome editing 2022 ·Molecular Genetics and Metabolism ·(unknown),Randy J. Chandler,(unknown),Victoria Hoffmann,(unknown),Susana Gordo,Nelson Chau,Charles P. Venditti	7
2	Evaluating the state of the science for adeno-associated virus integration: An integrated perspectivebreakdown → 2022 ·Molecular Therapy ·Denise E. Sabatino,Frederic D. Bushman,Randy J. Chandler,Ronald G. Crystal,Beverly L. Davidson,(unknown),Kevin Eggan,Guangping Gao,Irene Gil-Fariña,Mark A. Kay,Douglas M. McCarty,Eugenio Montini,(unknown),Jing Yuan	128
3	In vivo genome editing at the albumin locus to treat methylmalonic acidemia 2021 ·Molecular Therapy — Methods & Clinical Development ·Jessica L. Schneller,Ciaran M. Lee,(unknown),Randy J. Chandler,(unknown),(unknown),Thomas J. Cradick,Ayrea Hurley,William R. Lagor,Gang Bao,Charles P. Venditti	13
4	Central nervous system-targeted adeno-associated virus gene therapy in methylmalonic acidemia 2021 ·Molecular Therapy — Methods & Clinical Development ·Francis J. May,PamelaSara E. Head,(unknown),Randy J. Chandler,Charles P. Venditti	4
5	Low incidence of hepatocellular carcinoma in mice and cats treated with systemic adeno-associated viral vectors 2020 ·Molecular Therapy — Methods & Clinical Development ·Rita Ferla,(unknown),(unknown),Edoardo Nusco,John M. Cullen,Stephanie Smith,Tyra G. Wolfsberg,Patricia O’Donnell,Ping Wang,Anh‐Dao Nguyen,Randy J. Chandler,Zelin Chen,Shawn M. Burgess,Charles H. Vite,Mark E. Haskins,Charles P. Venditti,Alberto Auricchio	35
6	Enhanced Efficacy and Increased Long-Term Toxicity of CNS-Directed, AAV-Based Combination Therapy for Krabbe Disease 2020 ·Molecular Therapy ·Yedda Li,Christopher A. Miller,Lauren Shea,Xuntian Jiang,Miguel A. Guzmán,Randy J. Chandler,Sai Mukund Ramakrishnan,Stephanie Smith,Charles P. Venditti,Carole Vogler,Daniel S. Ory,Timothy J. Ley,Mark S. Sands	33
7	Gene Therapy for Methylmalonic Acidemia: Past, Present, and Future 2019 ·Human Gene Therapy ·Randy J. Chandler,Charles P. Venditti	30
8	Pathogenesis of Hepatic Tumors following Gene Therapy in Murine and Canine Models of Glycogen Storage Disease 2019 ·Molecular Therapy — Methods & Clinical Development ·(unknown),Monika Gjorgjieva,Stephanie Smith,Elizabeth D. Brooks,Zelin Chen,Shawn M. Burgess,Randy J. Chandler,(unknown),(unknown),Songtao Li,Gilles Mithieux,Charles P. Venditti,Fabienne Rajas,Dwight D. Koeberl	13
9	Genotoxicity in Mice Following AAV Gene Delivery: A Safety Concern for Human Gene Therapy? 2016 ·Molecular Therapy ·Randy J. Chandler,Matthew C. LaFave,Gaurav K. Varshney,Shawn M. Burgess,Charles P. Venditti	52
10	Gene therapy for metabolic diseases 2016 ·PubMed ·Randy J. Chandler,Charles P. Venditti	25
11	Systemic AAV9 gene therapy improves the lifespan of mice with Niemann-Pick disease, type C1 2016 ·Human Molecular Genetics ·Randy J. Chandler,Ian M. Williams,(unknown),Cristin Davidson,Arturo Incao,Brandon T. Hubbard,Forbes D. Porter,William J. Pavan,Charles P. Venditti	59
12	The proteome of methylmalonic acidemia (MMA): the elucidation of altered pathways in patient livers 2015 ·Molecular BioSystems ·Marianna Caterino,Randy J. Chandler,Jennifer L. Sloan,Kenneth Dorko,Kristina Cusmano‐Ozog,(unknown),Stephen C. Strom,Esther Imperlini,Emanuela Scolamiero,Charles P. Venditti,Margherita Ruoppolo	28
13	Pre-clinical efficacy and dosing of an AAV8 vector expressing human methylmalonyl-CoA mutase in a murine model of methylmalonic acidemia (MMA) 2012 ·Molecular Genetics and Metabolism ·Randy J. Chandler,Charles P. Venditti	23
14	Gene therapy in a murine model of methylmalonic acidemia using rAAV9-mediated gene delivery 2011 ·Gene Therapy ·Julien S. Senac,Randy J. Chandler,Justin R. Sysol,(unknown),Charles P. Venditti	22
15	Long-term Rescue of a Lethal Murine Model of Methylmalonic Acidemia Using Adeno associated Viral Gene Therapy 2009 ·Molecular Therapy ·Randy J. Chandler,Charles P. Venditti	37
16	Propionyl-CoA and adenosylcobalamin metabolism in Caenorhabditis elegans: Evidence for a role of methylmalonyl-CoA epimerase in intermediary metabolism 2006 ·Molecular Genetics and Metabolism ·Randy J. Chandler,(unknown),Mindy Tsai,Marni J. Falk,(unknown),(unknown),(unknown),Margaret M. Sedensky,Haig H. Kazazian,Charles P. Venditti	24
17	Genetic and genomic systems to study methylmalonic acidemia 2005 ·Molecular Genetics and Metabolism ·Randy J. Chandler,Charles P. Venditti	44
18	Resistant herpes infection of the palm in a patient with acquired immunodeficiency syndrome: A case report 1997 ·The Journal Of Hand Surgery ·(unknown),Randy J. Chandler,Aditya K. Gupta	1
19	Phosphorylation with protein kinases modulates calcium loading of terminal cisternae of sarcoplasmic reticulum from skeletal muscle 1995 ·Cell Calcium ·M. Mayrleitner,Randy J. Chandler,H. Schindler,Sidney Fleischer	26
20	Tryptic and chymotryptic proteases released by larvae of the blowfly, lucilia cuprina 1990 ·International Journal for Parasitology ·R.M. Sandeman,(unknown),Randy J. Chandler,Vernon M Bowles	47

About Randy J. Chandler

Randy J. Chandler is a scholar working on Clinical Biochemistry, Genetics and Molecular Biology, having authored 48 papers that have together received 2.0k indexed citations. Recurring topics across this work include Virus-based gene therapy research (24 papers), Metabolism and Genetic Disorders (20 papers) and CRISPR and Genetic Engineering (11 papers). The work is most often cited by research in Clinical Biochemistry (568 citations), Genetics (966 citations) and Molecular Biology (1.3k citations). Randy J. Chandler has collaborated with scholars based in United States, Italy and Australia. Frequent co-authors include Charles P. Venditti, Nuria Carrillo, Mark S. Sands, Victoria Hoffmann, Shawn M. Burgess, Gaurav K. Varshney, Matthew C. LaFave, Julien S. Senac, Jennifer L. Sloan and Guangping Gao. Their work appears in journals such as The Lancet, Journal of Clinical Investigation and Blood.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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