Denise E. Sabatino

5.6k citations

53 papers · 2.8k indexed · 3 hit papers · h-index 25

Co-authors: Katherine A. High Daniel J. Hui Federico Mingozzi Valder R. Arruda Glenn F. Pierce Haiyan Jiang Timothy C. Nichols Elizabeth P. Merricks
Topics: Virus-based gene therapy research (33 papers)Hemophilia Treatment and Research (22 papers)CAR-T cell therapy research (14 papers)
Cited by: Genetics Hematology Oncology
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Nature Medicine
Partner nations: United States Australia Canada

In The Last Decade

Denise E. Sabatino

53 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CD8+ T-cell responses to adeno-associated virus capsid in humans

2007 573 citations Federico Mingozzi, Marcela V. Maus et al. Nature Medicine profile →
A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells

2020 295 citations Giang N. Nguyen, J.K. Everett et al. Nature Biotechnology profile →
Evaluating the state of the science for adeno-associated virus integration: An integrated perspective

2022 128 citations Denise E. Sabatino, Frederic D. Bushman et al. Molecular Therapy profile →

Peers

Countries citing papers authored by Denise E. Sabatino

Since Specialization

Citations

This map shows the geographic impact of Denise E. Sabatino's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Denise E. Sabatino with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Denise E. Sabatino more than expected).

Fields of papers citing papers by Denise E. Sabatino

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Denise E. Sabatino. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Denise E. Sabatino. The network helps show where Denise E. Sabatino may publish in the future.

Co-authorship network of co-authors of Denise E. Sabatino

This figure shows the co-authorship network connecting the top 25 collaborators of Denise E. Sabatino. A scholar is included among the top collaborators of Denise E. Sabatino based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Denise E. Sabatino. Denise E. Sabatino is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Altered cleavage of human factor VIII at the B-domain and acidic region 3 interface enhances expression after gene therapy in hemophilia A mice 2023 ·Journal of Thrombosis and Haemostasis ·(unknown),(unknown),(unknown),Samita Kafle,(unknown),(unknown),Denise E. Sabatino	6
2	Coagulation factor VIII regulates von Willebrand factor homeostasis in vivo 2023 ·Journal of Thrombosis and Haemostasis ·(unknown),(unknown),(unknown),Lindsey A. George,Bhavya S. Doshi,Denise E. Sabatino,(unknown),Liang Zheng,Rodney M. Camire,X. Long Zheng	2
3	Evaluating the state of the science for adeno-associated virus integration: An integrated perspectivebreakdown → 2022 ·Molecular Therapy ·Denise E. Sabatino,Frederic D. Bushman,Randy J. Chandler,Ronald G. Crystal,Beverly L. Davidson,(unknown),Kevin Eggan,Guangping Gao,Irene Gil-Fariña,Mark A. Kay,Douglas M. McCarty,Eugenio Montini,(unknown),Jing Yuan	128
4	Preclinical assessment of an optimized AAV-FVIII vector in mice and non-human primates for the treatment of hemophilia A 2021 ·Molecular Therapy — Methods & Clinical Development ·(unknown),Sean M. Armour,Raffaella Toso,(unknown),Robert J. Davidson,Giang N. Nguyen,(unknown),(unknown),(unknown),(unknown),Marco Crosariol,Yuhuan Wang,Chuansong Wang,Katherine A. High,Denise E. Sabatino,Xavier M. Anguela	13
5	Challenges in estimating numbers of vectors integrated in gene-modified cells using DNA sequence information 2021 ·Molecular Therapy ·Frederic D. Bushman,Adrian Cantu,J.K. Everett,Denise E. Sabatino,Charles C. Berry	10
6	Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing 2020 ·Science Advances ·Xinfu Zhang,Weiyu Zhao,Giang N. Nguyen,Chengxiang Zhang,Chunxi Zeng,Jinyue Yan,Shi Du,Xucheng Hou,Wenqing Li,Justin Jiang,Binbin Deng,David W. McComb,(unknown),Aalok Shah,Luis Barrera,Francine M. Gregoire,Manmohan Singh,Delai Chen,Denise E. Sabatino,Yizhou Dong	151
7	A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cellsbreakdown → 2020 ·Nature Biotechnology ·Giang N. Nguyen,J.K. Everett,Samita Kafle,Aoife M. Roche,Hayley E. Raymond,Jacob S. Leiby,Christian M. Wood,Charles‐Antoine Assenmacher,Elizabeth P. Merricks,(unknown),Haig H. Kazazian,Timothy C. Nichols,Frederic D. Bushman,Denise E. Sabatino	295
8	Long-Term AAV-Mediated Factor VIII Expression in Nine Hemophilia A Dogs: A 10 Year Follow-up Analysis on Durability, Safety and Vector Integration 2019 ·Blood ·Giang N. Nguyen,J.K. Everett,Hayley E. Raymond,Samita Kafle,Elizabeth P. Merricks,Haig H. Kazazian,Timothy C. Nichols,Frederic D. Bushman,Denise E. Sabatino	24
9	Overexpression of factor VIII after AAV delivery is transiently associated with cellular stress in hemophilia A mice 2016 ·Molecular Therapy — Methods & Clinical Development ·(unknown),(unknown),Giang N. Nguyen,Denise E. Sabatino	64
10	Platelet‐delivered therapeutics 2015 ·Journal of Thrombosis and Haemostasis ·Randolph B. Lyde,Denise E. Sabatino,Spencer K. Sullivan,Mortimer Poncz	9
11	Muscle Gene Therapy for Hemophilia 2013 ·Journal of Genetic Syndromes & Gene Therapy ·Denise E. Sabatino,Valder R. Arruda	4
12	Light Chain of Factor VIII Is Sufficient for Accelerating Cleavage of von Willebrand Factor by ADAMTS13 Metalloprotease 2012 ·Journal of Biological Chemistry ·Wenjing Cao,Denise E. Sabatino,(unknown),(unknown),(unknown),Rodney M. Camire,X. Long Zheng	13
13	Animal Models of Hemophilia 2011 ·Progress in molecular biology and translational science ·Denise E. Sabatino,Timothy C. Nichols,Elizabeth P. Merricks,Dwight A. Bellinger,Roland W. Herzog,Paul E. Monahan	50
14	Diverse IgG subclass responses to adeno‐associated virus infection and vector administration 2008 ·Journal of Medical Virology ·Samuel L. Murphy,Hojun Li,Federico Mingozzi,Denise E. Sabatino,Daniel J. Hui,Shyrie Edmonson,Katherine A. High	83
15	CD8+ T-cell responses to adeno-associated virus capsid in humansbreakdown → 2007 ·Nature Medicine ·Federico Mingozzi,Marcela V. Maus,Daniel J. Hui,Denise E. Sabatino,Samuel L. Murphy,John E.J. Rasko,Margaret V. Ragni,Catherine S. Manno,Jürg M. Sommer,Haiyan Jiang,Glenn F. Pierce,Hildegund C.J. Ertl,Katherine A. High	573
16	Persistent Expression of hF.IX After Tolerance Induction by In Utero or Neonatal Administration of AAV-1-F.IX in Hemophilia B Mice 2007 ·Molecular Therapy ·Denise E. Sabatino,Tippi C. MacKenzie,William H. Peranteau,Shyrie Edmonson,Cesare Campagnoli,(unknown),Alan W. Flake,Katherine A. High	83
17	Development of a Stable Retrovirus Vector Capable of Long‐Term Expression of γ‐Globin mRNA in Mouse Erythrocytes 2001 ·Annals of the New York Academy of Sciences ·Denise E. Sabatino,Nancy E. Seidel,Amanda P. Cline,Stacie M. Anderson,Patrick G. Gallagher,David M. Bodine	6
18	A Human β-Spectrin Gene Promoter Directs High Level Expression in Erythroid but Not Muscle or Neural Cells 1999 ·Journal of Biological Chemistry ·Patrick G. Gallagher,Denise E. Sabatino,Marc Romana,Amanda P. Cline,Lisa Garrett,David M. Bodine,Bernard G. Forget	27
19	Amphotropic or Gibbon Ape Leukemia Virus Retrovirus Binding and Transduction Correlates with the Level of Receptor mRNA in Human Hematopoietic Cell Lines 1997 ·Blood Cells Molecules and Diseases ·Denise E. Sabatino,(unknown),Louise C. Pyle,Nancy E. Seidel,(unknown),S. Kaye Spratt,Donald Orlic,David M. Bodine	50
20	Distal 8p deletion (8)(p23.1): An easily missed chromosomal abnormality that may be associated with congenital heart defect and mental retardation 1996 ·American Journal of Medical Genetics ·Bai‐Lin Wu,Gretchen Schneider,Denise E. Sabatino,(unknown),(unknown),Bruce R. Korf	52

About Denise E. Sabatino

Denise E. Sabatino is a scholar working on Hematology, Genetics and Oncology, having authored 53 papers that have together received 2.8k indexed citations. Recurring topics across this work include Virus-based gene therapy research (33 papers), Hemophilia Treatment and Research (22 papers) and CAR-T cell therapy research (14 papers). The work is most often cited by research in Genetics (1.8k citations), Hematology (526 citations) and Oncology (739 citations). Denise E. Sabatino has collaborated with scholars based in United States, Australia and Canada. Frequent co-authors include Katherine A. High, Daniel J. Hui, Federico Mingozzi, Valder R. Arruda, Glenn F. Pierce, Haiyan Jiang, Timothy C. Nichols, Elizabeth P. Merricks, Samuel L. Murphy and Hildegund C.J. Ertl. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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