Denise E. Sabatino

5.6k total citations · 3 hit papers
53 papers, 2.8k citations indexed

About

Denise E. Sabatino is a scholar working on Genetics, Molecular Biology and Hematology. According to data from OpenAlex, Denise E. Sabatino has authored 53 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 38 papers in Genetics, 28 papers in Molecular Biology and 25 papers in Hematology. Recurrent topics in Denise E. Sabatino's work include Virus-based gene therapy research (33 papers), Hemophilia Treatment and Research (22 papers) and CAR-T cell therapy research (14 papers). Denise E. Sabatino is often cited by papers focused on Virus-based gene therapy research (33 papers), Hemophilia Treatment and Research (22 papers) and CAR-T cell therapy research (14 papers). Denise E. Sabatino collaborates with scholars based in United States, Australia and Canada. Denise E. Sabatino's co-authors include Katherine A. High, Daniel J. Hui, Federico Mingozzi, Valder R. Arruda, Glenn F. Pierce, Haiyan Jiang, Elizabeth P. Merricks, Timothy C. Nichols, Samuel L. Murphy and Hildegund C.J. Ertl and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Medicine.

In The Last Decade

Denise E. Sabatino

53 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CD8+ T-cell responses to adeno-associated virus capsid in humans

2007 573 citations Federico Mingozzi, Marcela V. Maus et al. Nature Medicine profile →
A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells

2020 295 citations Giang N. Nguyen, J.K. Everett et al. Nature Biotechnology profile →
Evaluating the state of the science for adeno-associated virus integration: An integrated perspective

2022 128 citations Denise E. Sabatino, Frederic D. Bushman et al. Molecular Therapy profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Denise E. Sabatino United States	25	1.8k	1.8k	739	526	279	53	2.8k
Amit C. Nathwani United Kingdom	32	2.6k 1.4×	2.4k 1.3×	1.1k 1.5×	651 1.2×	395 1.4×	88	3.7k
Gregory M. Podsakoff United States	14	1.8k 1.0×	1.7k 0.9×	633 0.9×	258 0.5×	247 0.9×	19	2.4k
John T. Gray United States	28	1.7k 1.0×	2.1k 1.2×	682 0.9×	161 0.3×	277 1.0×	55	2.8k
David M. Markusic United States	26	1.4k 0.8×	1.5k 0.8×	641 0.9×	298 0.6×	242 0.9×	54	2.4k
Ute Modlich Germany	28	2.1k 1.1×	2.8k 1.5×	1.1k 1.4×	292 0.6×	175 0.6×	78	3.7k
Mark E. Metzger United States	34	2.0k 1.1×	2.3k 1.3×	949 1.3×	806 1.5×	241 0.9×	94	3.7k
Xavier M. Anguela United States	17	1.3k 0.7×	1.7k 0.9×	476 0.6×	205 0.4×	155 0.6×	31	2.2k
Pietro Genovese United States	16	1.4k 0.8×	2.4k 1.3×	853 1.2×	201 0.4×	128 0.5×	35	3.0k
Linda B. Couto United States	22	3.2k 1.8×	2.8k 1.5×	1.4k 1.8×	467 0.9×	399 1.4×	31	3.9k
Salima Hacein‐Bey‐Abina France	31	2.1k 1.1×	2.1k 1.1×	1.1k 1.5×	534 1.0×	238 0.9×	84	3.7k

Countries citing papers authored by Denise E. Sabatino

Since Specialization

Citations

This map shows the geographic impact of Denise E. Sabatino's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Denise E. Sabatino with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Denise E. Sabatino more than expected).

Fields of papers citing papers by Denise E. Sabatino

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Denise E. Sabatino. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Denise E. Sabatino. The network helps show where Denise E. Sabatino may publish in the future.

Co-authorship network of co-authors of Denise E. Sabatino

This figure shows the co-authorship network connecting the top 25 collaborators of Denise E. Sabatino. A scholar is included among the top collaborators of Denise E. Sabatino based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Denise E. Sabatino. Denise E. Sabatino is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kafle, Samita, et al.. (2023). Altered cleavage of human factor VIII at the B-domain and acidic region 3 interface enhances expression after gene therapy in hemophilia A mice. Journal of Thrombosis and Haemostasis. 21(8). 2101–2113. 6 indexed citations

George, Lindsey A., Bhavya S. Doshi, Denise E. Sabatino, et al.. (2023). Coagulation factor VIII regulates von Willebrand factor homeostasis in vivo. Journal of Thrombosis and Haemostasis. 21(12). 3477–3489. 2 indexed citations

Sabatino, Denise E., Frederic D. Bushman, Randy J. Chandler, et al.. (2022). Evaluating the state of the science for adeno-associated virus integration: An integrated perspective. Molecular Therapy. 30(8). 2646–2663. 128 indexed citations breakdown →

Armour, Sean M., Raffaella Toso, Robert J. Davidson, et al.. (2021). Preclinical assessment of an optimized AAV-FVIII vector in mice and non-human primates for the treatment of hemophilia A. Molecular Therapy — Methods & Clinical Development. 24. 20–29. 13 indexed citations

Zhang, Xinfu, Weiyu Zhao, Giang N. Nguyen, et al.. (2020). Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing. Science Advances. 6(34). 151 indexed citations

Nguyen, Giang N., J.K. Everett, Samita Kafle, et al.. (2020). A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells. Nature Biotechnology. 39(1). 47–55. 295 indexed citations breakdown →

Nguyen, Giang N., J.K. Everett, Hayley E. Raymond, et al.. (2019). Long-Term AAV-Mediated Factor VIII Expression in Nine Hemophilia A Dogs: A 10 Year Follow-up Analysis on Durability, Safety and Vector Integration. Blood. 134(Supplement_1). 611–611. 24 indexed citations

Lyde, Randolph B., Paul Gadue, Deborah L. French, et al.. (2019). A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis. Blood. 134(Supplement_1). 1102–1102. 2 indexed citations

Lyde, Randolph B., Denise E. Sabatino, Spencer K. Sullivan, & Mortimer Poncz. (2015). Platelet‐delivered therapeutics. Journal of Thrombosis and Haemostasis. 13. S143–S150. 9 indexed citations

10.

Sabatino, Denise E. & Valder R. Arruda. (2013). Muscle Gene Therapy for Hemophilia. Journal of Genetic Syndromes & Gene Therapy. S1(2). 4 indexed citations

11.

Sabatino, Denise E., et al.. (2013). Minimal modification in the factor VIII B-domain sequence ameliorates the murine hemophilia A phenotype. Blood. 121(21). 4396–4403. 70 indexed citations

12.

Cao, Wenjing, et al.. (2012). Light Chain of Factor VIII Is Sufficient for Accelerating Cleavage of von Willebrand Factor by ADAMTS13 Metalloprotease. Journal of Biological Chemistry. 287(39). 32459–32466. 13 indexed citations

13.

Sabatino, Denise E., Timothy C. Nichols, Elizabeth P. Merricks, et al.. (2011). Animal Models of Hemophilia. Progress in molecular biology and translational science. 105. 151–209. 50 indexed citations

14.

Murphy, Samuel L., Hojun Li, Federico Mingozzi, et al.. (2008). Diverse IgG subclass responses to adeno‐associated virus infection and vector administration. Journal of Medical Virology. 81(1). 65–74. 83 indexed citations

15.

Mingozzi, Federico, Marcela V. Maus, Daniel J. Hui, et al.. (2007). CD8+ T-cell responses to adeno-associated virus capsid in humans. Nature Medicine. 13(4). 419–422. 573 indexed citations breakdown →

16.

Murphy, Samuel L., Denise E. Sabatino, Federico Mingozzi, Shyrie Edmonson, & Katherine A. High. (2006). 74. Cellular Immunity to Adeno-Associated Virus Capsid Attenuates Transgene Expression in the Liver. Molecular Therapy. 13. S31–S32. 2 indexed citations

17.

Sabatino, Denise E., et al.. (2003). Optimized Production of High-Titer Recombinant Adeno-Associated Virus in Roller Bottles. BioTechniques. 34(1). 184–189. 54 indexed citations

18.

Sabatino, Denise E., Nancy E. Seidel, Amanda P. Cline, et al.. (2001). Development of a Stable Retrovirus Vector Capable of Long‐Term Expression of γ‐Globin mRNA in Mouse Erythrocytes. Annals of the New York Academy of Sciences. 938(1). 246–261. 6 indexed citations

19.

Gallagher, Patrick G., Denise E. Sabatino, Marc Romana, et al.. (1999). A Human β-Spectrin Gene Promoter Directs High Level Expression in Erythroid but Not Muscle or Neural Cells. Journal of Biological Chemistry. 274(10). 6062–6073. 27 indexed citations

20.

Wu, Bai‐Lin, et al.. (1996). Distal 8p deletion (8)(p23.1): An easily missed chromosomal abnormality that may be associated with congenital heart defect and mental retardation. American Journal of Medical Genetics. 62(1). 77–83. 52 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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