Kenneth Dorko

5.5k citations

51 papers · 4.3k indexed · 2 hit papers · h-index 31

Impact in

Hepatology top 0.5%
- Liver physiology and pathology
Pharmacology top 0.5%
- Drug-Induced Hepatotoxicity and Protection

Papers in

Hepatology 22
- Liver physiology and pathology 18
Clinical Biochemistry 8
- Metabolism and Genetic Disorders 8

Co-authors: Stephen C. Strom James E. Esplen Minji Jo Timothy R. Billiar Tae‐Hyoung Kim Dai‐Wu Seol Ira J. Fox Bernhard Sauter
Journals: Drug Metabolism and Disposition (6 papers)Cell Transplantation (5 papers)Journal of Biological Chemistry (4 papers)Hepatology (3 papers)Toxicology and Applied Pharmacology (3 papers)
Partner nations: United States Sweden Italy

In The Last Decade

Kenneth Dorko

51 papers receiving 4.2k citations

Hit Papers

align trajectories log scale

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand 2000 · 705 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2000 Nature Medicine
1998 New England Journal of Medicine

Peers

Countries citing papers authored by Kenneth Dorko

Since Specialization

Citations

This map shows the geographic impact of Kenneth Dorko's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth Dorko with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth Dorko more than expected).

Fields of papers citing papers by Kenneth Dorko

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth Dorko. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth Dorko. The network helps show where Kenneth Dorko may publish in the future.

Co-authors

The 25 scholars most cited alongside Kenneth Dorko, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kenneth Dorko Line = papers co-authored together Kenneth Dorko links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen Hepatotoxicity Journal of Clinical and Translational Research ·Yuchao Xie, Benjamin L. Woolbright, Milan Kos, Mitchell R. McGill, Kenneth Dorko, Sean Kumer, Timothy M. Schmitt, Hartmut Jaeschke	2015	7
2	The proteome of methylmalonic acidemia (MMA): the elucidation of altered pathways in patient livers Molecular BioSystems ·Marianna Caterino, Randy J. Chandler, Jennifer L. Sloan, Kenneth Dorko, Kristina Cusmano‐Ozog, Laura Ingenito, Stephen C. Strom, Esther Imperlini, Emanuela Scolamiero, Charles P. Venditti, Margherita Ruoppolo	2015	28
3	Dynamic Arginine Methylation of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 Regulates Toll-like Receptor Signaling Journal of Biological Chemistry ·Irina Tikhanovich, Sudhakiranmayi Kuravi, Antonio Artigues, María T. Villar, Kenneth Dorko, Atta Nawabi, Benjamin Roberts, Steven A. Weinman	2015	61
4	Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis Toxicology and Applied Pharmacology ·Benjamin L. Woolbright, Kenneth Dorko, Daniel J. Antoine, Joanna I. Clarke, Parviz Gholami, Feng Li, Sean Kumer, Timothy M. Schmitt, Jameson Forster, Fang Fan, Rosalind E. Jenkins, B. Kevin Park, Bruno Hagenbuch, Mojtaba Olyaee, Hartmut Jaeschke	2015	151
5	Liver-Regenerative Transplantation: Regrow and Reset American Journal of Transplantation ·Alexandra Collin de l’Hortet, Kazuki Takeishi, Jorge Guzman‐Lepe, Kan Handa, Kentaro Matsubara, Ken Fukumitsu, Kenneth Dorko, Sharon C. Presnell, Hiroshi Yagi, Alejandro Soto–Gutiérrez	2015	32
6	Functional Coupling of ATP-binding Cassette Transporter Abcb6 to Cytochrome P450 Expression and Activity in Liver Journal of Biological Chemistry ·Hemantkumar Chavan, Feng Li, Robert Tessman, Kristen Mickey, Kenneth Dorko, Timothy M. Schmitt, Sean Kumer, Sumedha Gunewardena, Nilesh W. Gaikwad, Partha Krishnamurthy	2015	10
7	Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes Toxicology and Applied Pharmacology ·Yuchao Xie, Mitchell R. McGill, Kuo Du, Kenneth Dorko, Sean Kumer, Timothy M. Schmitt, Wen‐Xing Ding, Hartmut Jaeschke	2015	74
8	Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase Journal of Biological Chemistry ·Shih-Chia Tso, W.J. Gui, Cheng‐Yang Wu, Jacinta L. Chuang, Xiangbing Qi, Kristen J. Skvorak, Kenneth Dorko, Amy L. Wallace, Lorraine Morlock, Brendan H. Lee, Susan M. Hutson, Stephen C. Strom, Noelle S. Williams, Uttam K. Tambar, Richard Wynn, David Chuang	2014	72
9	Human pathophysiological concentrations of bile salts induce necrosis in primary human hepatocytes (398.1) The FASEB Journal ·Benjamin L. Woolbright, Feng Li, Parviz Gholami, Kenneth Dorko, Sean Kumer, Timothy M. Schmitt, Jameson Forster, Mojtaba Olyaee, Bruno Hagenbuch, Hartmut Jaeschke	2014	2
10	Mechanisms of acetaminophen-induced cell death in primary human hepatocytes Toxicology and Applied Pharmacology ·Yuchao Xie, Mitchell R. McGill, Kenneth Dorko, Sean Kumer, Timothy M. Schmitt, Jameson Forster, Hartmut Jaeschke	2014	196
11	Bedaquiline Metabolism: Enzymes and Novel Metabolites Drug Metabolism and Disposition ·Ke Liu, Feng Li, Jie Lu, Shinlan Liu, Kenneth Dorko, Wen Xie, Xiaochao Ma	2014	35
12	New potential cell source for hepatocyte transplantation: Discarded livers from metabolic disease liver transplants Stem Cell Research ·Roberto Gramignoli, Veysel Tahan, Kenneth Dorko, Kristen J. Skvorak, Marc C. Hansel, Wenchen Zhao, Raman Venkataramanan, Ewa Ellis, Carl Jorns, Bo-Göran Ericzon, Staffan Rosenborg, Raoul Kuiper, Kyle Soltys, George Mazariegos, Ira J. Fox, Elizabeth M. Wilson, Markus Grompe, Stephen C. Strom	2013	44
13	Hepatic differentiation of amniotic epithelial cells Hepatology ·Fabio Marongiu, Roberto Gramignoli, Kenneth Dorko, Toshio Miki, Aarati R. Ranade, Maria Paola Serra, Silvia Doratiotto, Marcella Sini, Shringi Sharma, Keitaro Mitamura, Tiffany L. Sellaro, Veysel Tahan, Kristen J. Skvorak, Ewa Ellis, Stephen F. Badylak, Julio C. Dávila, Ronald N. Hines, Ezio Laconi, Stephen C. Strom	2011	109
14	The second extracellular loop dictates Occludin-mediated HCV entry Virology ·Shufeng Liu, Wayne Kuo, Wei Yang, Weiqun Liu, Gregory A. Gibson, Kenneth Dorko, Simon C. Watkins, Stephen C. Strom, Tianyi Wang	2010	39
15	Hepatocyte Transplantation Improves Phenotype and Extends Survival in a Murine Model of Intermediate Maple Syrup Urine Disease Molecular Therapy ·Kristen J. Skvorak, Harbhajan S. Paul, Kenneth Dorko, Fabio Marongiu, Ewa Ellis, Donald H. Chace, Carolyn Ferguson, K. Michael Gibson, Gregg E. Homanics, Stephen C. Strom	2009	28
16	Maintenance of Human Hepatocyte Function In Vitro by Liver-Derived Extracellular Matrix Gels Tissue Engineering Part A ·Tiffany L. Sellaro, Aarati R. Ranade, Denver M. Faulk, George P. McCabe, Kenneth Dorko, Stephen F. Badylak, Stephen C. Strom	2009	228
17	Cross-talk between Epidermal Growth Factor Receptor and c-Met Signal Pathways in Transformed Cells Journal of Biological Chemistry ·Minji Jo, Donna B. Stolz, James E. Esplen, Kenneth Dorko, George K. Michalopoulos, Stephen C. Strom	2000	287
18	Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand Nature Medicine ·Minji Jo, Tae‐Hyoung Kim, Dai‐Wu Seol, James E. Esplen, Kenneth Dorko, Timothy R. Billiar, Stephen C. Strom Hit paper breakdown →	2000	705
19	Troglitazone Increases Cytochrome P-450 3A Protein and Activity in Primary Cultures of Human Hepatocytes Drug Metabolism and Disposition ·Veerakumar Ramachandran, V.E. Kostrubsky, Bernard J. Komoroski, Shimin Zhang, Kenneth Dorko, James E. Esplen, S C Strom, R. Venkataramanan	1999	53
20	[42] Use of human hepatocytes to study P450 gene induction Methods in enzymology on CD-ROM/Methods in enzymology ·Stephen C. Strom, Liubomir A. Pisarov, Kenneth Dorko, Melissa Thompson, John D. Schuetz, Erin G. Schuetz	1996	153

About Kenneth Dorko

Kenneth Dorko is a scholar working on Hepatology, Clinical Biochemistry, Pharmacology, Biochemistry and Oncology, having authored 51 papers that have together received 4.3k indexed citations. Recurring topics across this work include Liver physiology and pathology (18 papers), Pancreatic function and diabetes (10 papers), Drug Transport and Resistance Mechanisms (10 papers), Organ Transplantation Techniques and Outcomes (9 papers), Metabolism and Genetic Disorders (8 papers), Drug-Induced Hepatotoxicity and Protection (6 papers), Pharmacogenetics and Drug Metabolism (6 papers) and Liver Disease Diagnosis and Treatment (6 papers). The work is most often cited by research in Hepatology (1.6k citations), Pharmacology (587 citations), Surgery (1.7k citations), Genetics (324 citations) and Clinical Biochemistry (197 citations). Kenneth Dorko has collaborated with scholars based in United States, Sweden and Italy. Frequent co-authors include Stephen C. Strom, James E. Esplen, Minji Jo, Timothy R. Billiar, Tae‐Hyoung Kim, Dai‐Wu Seol, Ira J. Fox, Bernhard Sauter, Namita Roy Chowdhury and Stuart S. Kaufman. Their work appears in journals such as Drug Metabolism and Disposition, Cell Transplantation, Journal of Biological Chemistry, Hepatology and Toxicology and Applied Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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