Paul H. Wen

2.2k citations

24 papers · 1.4k indexed · h-index 14

Molecular Biology top 10%
Physiology top 5%
Cellular and Molecular Neuroscience top 5%
Developmental Neuroscience top 2%
Pharmacology top 5%

Co-authors: Nikolaos K. Robakis Junichi Shioi Philippe Marambaud Robert Siman Akihiko Takashima Lia Baki Zhiping Shao Gregory A. Elder
Topics: Alzheimer's disease research and treatments (11 papers)Neurogenesis and neuroplasticity mechanisms (6 papers)Cholinesterase and Neurodegenerative Diseases (3 papers)
Cited by: Developmental Neuroscience Physiology Cellular and Molecular Neuroscience
Journals: Cell Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States Japan Australia

In The Last Decade

Paul H. Wen

24 papers receiving 1.4k citations

Peers

Countries citing papers authored by Paul H. Wen

Since Specialization

Citations

This map shows the geographic impact of Paul H. Wen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul H. Wen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul H. Wen more than expected).

Fields of papers citing papers by Paul H. Wen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul H. Wen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul H. Wen. The network helps show where Paul H. Wen may publish in the future.

Co-authorship network of co-authors of Paul H. Wen

This figure shows the co-authorship network connecting the top 25 collaborators of Paul H. Wen. A scholar is included among the top collaborators of Paul H. Wen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul H. Wen. Paul H. Wen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Identification of normal and depression EEG signals in variational mode decomposition domain 2022 ·Health Information Science and Systems ·Hesam Akbari,Muhammad Tariq Sadiq,Siuly Siuly,Yan Li,Paul H. Wen	12
2	The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement 2020 ·Bioorganic & Medicinal Chemistry Letters ·Michael Frohn,Longbin Liu,Aaron C. Siegmund,Wenyuan Qian,Albert Amegadzie,Ning Chen,(unknown),Dean Hickman,Stephen Wood,Paul H. Wen,Michael D. Bartberger,Douglas A. Whittington,Jennifer R. Allen,Matthew P. Bourbeau	4
3	TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer's disease variant Trem2R47H on murine myeloid cell function 2018 ·Journal of Biological Chemistry ·Qingwen Cheng,Jean Danao,(unknown),Paul H. Wen,Jun Yin,Ning Sun,Chi-Ming Li,Danny Chui,David Tran,Samir Koirala,Hang Chen,Ian N. Foltz,Songli Wang,Shilpa Sambashivan	69
4	Effect of LXR/RXR agonism on brain and CSF Aβ40 levels in rats [version 2; referees: 1 approved, 2 approved with reservations] 2016 ·Songli Wang,Paul H. Wen,Stephen Wood	1
5	Lead Optimization and Modulation of hERG Activity in a Series of Aminooxazoline Xanthene β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors 2014 ·Journal of Medicinal Chemistry ·O. I. Epstein,Marian C. Bryan,Alan C. Cheng,Katayoun Derakhchan,Thomas A. Dineen,Dean Hickman,Zihao Hua,(unknown),(unknown),Isaac E. Marx,Matthew M. Weiss,Robert C. Wahl,Paul H. Wen,Douglas A. Whittington,Stephen Wood,(unknown),Robert T. Fremeau,Ryan D. White,Vinod F. Patel	32
6	Inhibitors of β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1): Identification of (S)-7-(2-Fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5′H-spiro[chromeno[2,3-b]pyridine-5,4′-oxazol]-2′-amine (AMG-8718) 2014 ·Journal of Medicinal Chemistry ·Thomas A. Dineen,Kui Chen,Alan C. Cheng,Katayoun Derakhchan,O. I. Epstein,(unknown),Dean Hickman,(unknown),Isaac E. Marx,Robert C. Wahl,Paul H. Wen,Matthew M. Weiss,Douglas A. Whittington,Stephen Wood,Robert T. Fremeau,Ryan D. White,Vinod F. Patel	49
7	Establishing the Relationship between In Vitro Potency, Pharmacokinetic, and Pharmacodynamic Parameters in a Series of Orally Available, Hydroxyethylamine-Derived β-Secretase Inhibitors 2012 ·Journal of Pharmacology and Experimental Therapeutics ·Stephen Wood,Paul H. Wen,Jianhua Zhang,Li Zhu,Yi Luo,Safura Babu‐Khan,Kui Chen,(unknown),(unknown),Thomas A. Dineen,Matthew R. Kaller,Matthew M. Weiss,Stephen A. Hitchcock,Martin Citron,Wenge Zhong,Dean Hickman,Toni Williamson	8
8	Structure- and Property-Based Design of Aminooxazoline Xanthenes as Selective, Orally Efficacious, and CNS Penetrable BACE Inhibitors for the Treatment of Alzheimer’s Disease 2012 ·Journal of Medicinal Chemistry ·Hongbing Huang,Daniel S. La,Alan C. Cheng,Douglas A. Whittington,Vinod F. Patel,Kui Chen,Thomas A. Dineen,O. I. Epstein,Russell F. Graceffa,Dean Hickman,Y.-H. Kiang,Steven W. Louie,Yi Luo,Robert C. Wahl,Paul H. Wen,Stephen Wood,Robert T. Fremeau	51
9	Cortical development in the presenilin‐1 null mutant mouse fails after splitting of the preplate and is not due to a failure of reelin‐dependent signaling 2008 ·Developmental Dynamics ·Rita De Gasperi,Miguel A. Gama Sosa,Paul H. Wen,Jingjun Li,Gissel M. Perez,Tom Curran,Gregory A. Elder	7
10	Selective expression of presenilin 1 in neural progenitor cells rescues the cerebral hemorrhages and cortical lamination defects in presenilin 1-null mutant mice 2005 ·Development ·Paul H. Wen,Rita De Gasperi,Miguel A. Gama Sosa,Anne B. Rocher,Victor L. Friedrich,Patrick R. Hof,Gregory A. Elder	27
11	Neural progenitor cells do not differentiate prematurely in presenilin-1 null mutant mice 2004 ·Neuroscience Letters ·Paul H. Wen,Rita De Gasperi,Miguel A. Gama Sosa,Gregory A. Elder	4
12	The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice 2004 ·Experimental Neurology ·Paul H. Wen,Patrick R. Hof,Xiaoping Chen,(unknown),Gregory L. Austin,Steven G. Younkin,Linda H. Younkin,Rita DeGasperi,Miguel A. Gama Sosa,Nikolaos K. Robakis,Vahram Haroutunian,Gregory A. Elder	154
13	PS1 activates PI3K thus inhibiting GSK‐3 activity and tau overphosphorylation: effects of FAD mutations 2004 ·The EMBO Journal ·Lia Baki,Junichi Shioi,Paul H. Wen,Zhiping Shao,A. L. Schwarzman,Miguel A. Gama-Sosa,Rachael L. Neve,Nikolaos K. Robakis	247
14	Transgenic rescue of Krabbe disease in the twitcher mouse 2004 ·Gene Therapy ·Rita De Gasperi,Victor L. Friedrich,Gissel M. Perez,Emir Senturk,Paul H. Wen,Kevin A. Kelley,Gregory A. Elder,Miguel A. Gama Sosa	22
15	A CBP Binding Transcriptional Repressor Produced by the PS1/ϵ-Cleavage of N-Cadherin Is Inhibited by PS1 FAD Mutations 2003 ·Cell ·Philippe Marambaud,Paul H. Wen,(unknown),Junichi Shioi,Akihiko Takashima,Robert Siman,Nikolaos K. Robakis	400
16	Human midsized neurofilament subunit induces motor neuron disease in transgenic mice 2003 ·Experimental Neurology ·Miguel A. Gama Sosa,Victor L. Friedrich,Rita DeGasperi,Kevin A. Kelley,Paul H. Wen,Emir Senturk,Robert A. Lazzarini,Gregory A. Elder	25
17	Overexpression of Wild Type But Not an FAD Mutant Presenilin-1 Promotes Neurogenesis in the Hippocampus of Adult Mice 2002 ·Neurobiology of Disease ·Paul H. Wen,Xiang Shao,Zhiping Shao,Patrick R. Hof,Thomas Wısnıewskı,Kevin A. Kelley,Victor L. Friedrich,Lap Ho,Giulio Maria Pasinetti,Junichi Shioi,Nikolaos K. Robakis,Gregory A. Elder	90
18	Presenilin-1 is expressed in neural progenitor cells in the hippocampus of adult mice 2002 ·Neuroscience Letters ·Paul H. Wen,Victor L. Friedrich,Junichi Shioi,Nikolaos K. Robakis,Gregory A. Elder	25
19	BAC and PAC DNA for the Generation of Transgenic Animals 2002 ·BioTechniques ·Miguel A. Gama Sosa,Rita De Gasperi,Paul H. Wen,(unknown),Kevin A. Kelley,Robert A. Lazzarini,Gregory A. Elder	9
20	Role of Electrostatic Interactions in Defining the Potency of Neurotoxin B-IV from Cerebratulus lacteus 1996 ·Journal of Biological Chemistry ·Paul H. Wen,Kenneth M. Blumenthal	4

About Paul H. Wen

Paul H. Wen is a scholar working on Developmental Neuroscience, Physiology and Neurology, having authored 24 papers that have together received 1.4k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (11 papers), Neurogenesis and neuroplasticity mechanisms (6 papers) and Cholinesterase and Neurodegenerative Diseases (3 papers). The work is most often cited by research in Developmental Neuroscience (231 citations), Physiology (674 citations) and Cellular and Molecular Neuroscience (369 citations). Paul H. Wen has collaborated with scholars based in United States, Japan and Australia. Frequent co-authors include Nikolaos K. Robakis, Junichi Shioi, Philippe Marambaud, Robert Siman, Akihiko Takashima, Lia Baki, Zhiping Shao, Gregory A. Elder, Victor L. Friedrich and Miguel A. Gama-Sosa. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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