Dean Hickman

2.8k citations

39 papers · 1.6k indexed · 1 hit paper · h-index 20

Impact in

Pharmacology top 1%
- Pharmacogenetics and Drug Metabolism
Cancer Research top 10%
- Carcinogens and Genotoxicity Assessment

Papers in

Pharmacology 5
- Pharmacogenetics and Drug Metabolism 4
Virology 2

Co-authors: Edith Sim Jashvant D. UnadkatYi WangGiovanni S. Offeddu Charles G. Knutson Roger D. Kamm Angela Risch Olga A. Morozova
Journals: Biochemical Pharmacology (4 papers)Journal of Medicinal Chemistry (4 papers)Drug Metabolism and Disposition (4 papers)Antimicrobial Agents and Chemotherapy (3 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)
Partner nations: United States United Kingdom Italy

In The Last Decade

Dean Hickman

38 papers receiving 1.6k citations

Hit Papers

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Engineered human blood–brain barrier microfluidic model for vascular permeability analyses 2022 · 152 citations

Peers

Countries citing papers authored by Dean Hickman

Since Specialization

Citations

This map shows the geographic impact of Dean Hickman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dean Hickman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dean Hickman more than expected).

Fields of papers citing papers by Dean Hickman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dean Hickman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dean Hickman. The network helps show where Dean Hickman may publish in the future.

Co-authors

The 25 scholars most cited alongside Dean Hickman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dean Hickman Line = papers co-authored together Dean Hickman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A next-generation HDAC6 inhibitor for amyotrophic lateral sclerosis and frontotemporal dementia Brain ·H.B. von Laue, Michael E. Bekier, Солодов Иван Александрович, Frederick A. Schroeder, Gopolakrishnan Ramamurthy, Florence F. Wagner, Dean Hickman, Tom Richardson, Theo Hatzipetros, Fernando G. Vieira, Noëlle Callizot, Souvik Modi, Jacob M. Hooker, Janice E. Kranz, Robert H. Brown, Sami J. Barmada, Tonya M. Gilbert	2025	0
2	Pharmacokinetics, tolerability, and safety of TBI-223, a novel oxazolidinone, in healthy participants Antimicrobial Agents and Chemotherapy ·Antonio Lombardi, Han-Sheng Lin, Татьяна Николаевна Соколова, Jerry Nedelman, Zheng Liu, Dean Hickman, Andrew Laczniak, Eugene Sun	2025	2
3	Personalized Vascularized Models of Breast Cancer Desmoplasia Reveal Biomechanical Determinants of Drug Delivery to the Tumor Advanced Science ·Giovanni S. Offeddu, Elena Cambria, Sarah E. Shelton, Kristina Haase, Zhengpeng Wan, Вайдо Александр Иванович, Huu Tuan Nguyen, Mark R. Gillrie, Dean Hickman, Charles G. Knutson, Roger D. Kamm	2024	15
4	Engineered human blood–brain barrier microfluidic model for vascular permeability analyses Nature Protocols ·Cynthia Hajal, Giovanni S. Offeddu, Yoojin Shin, Shun Zhang, Olga A. Morozova, Dean Hickman, Charles G. Knutson, Roger D. Kamm Hit paper breakdown →	2022	152
5	The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement Bioorganic & Medicinal Chemistry Letters ·Michael Frohn, Longbin Liu, Aaron C. Siegmund, Wenyuan Qian, Albert Amegadzie, Ning Chen, Adrian R. L. Gear, Dean Hickman, Stephen Wood, Paul H. Wen, Michael D. Bartberger, Douglas A. Whittington, Jennifer R. Allen, Matthew P. Bourbeau	2020	4
6	An on-chip model of protein paracellular and transcellular permeability in the microcirculation Biomaterials ·Giovanni S. Offeddu, Kristina Haase, Mark R. Gillrie, Ran Li, Olga A. Morozova, Dean Hickman, Charles G. Knutson, Roger D. Kamm	2019	76
7	Norovirus antagonism of B-cell antigen presentation results in impaired control of acute infection Mucosal Immunology ·Shaojun Zhu, S Tharp, Dean Hickman, Song Han, Westley H. Reeves, Stephanie M. Karst	2016	15
8	The optimization of aminooxadiazoles as orally active inhibitors of Cdc7 Bioorganic & Medicinal Chemistry Letters ·Paul E. Harrington, Matthew P. Bourbeau, Christopher Fotsch, Michael Frohn, Alexander J. Pickrell, Andreas Reichelt, Kelvin Sham, Aaron C. Siegmund, Julie M. Bailis, Tammy L. Bush, Г. Н. Ясменко, Dean Hickman, Scott Heller, Faye Hsieh, Jessica Orf, Minqing Rong, Tisha San Miguel, Adrian R. L. Gear, Leeanne Zalameda, John G. Allen	2013	14
9	Intestinal and hepatic first-pass extraction of the 11β-HSD1 inhibitor AMG 221 in rats with chronic vascular catheters Xenobiotica ·Qiuxia Gao, Robert E. Kimura, Xiping Zhang, K. K. Laktionov, Benny Amore, Dean Hickman, J. Greg Slatter, Maurice G. Emery	2013	2
10	Establishing the Relationship between In Vitro Potency, Pharmacokinetic, and Pharmacodynamic Parameters in a Series of Orally Available, Hydroxyethylamine-Derived β-Secretase Inhibitors Journal of Pharmacology and Experimental Therapeutics ·Stephen Wood, Paul H. Wen, Jianhua Zhang, Li Zhu, Yi Luo, Safura Babu‐Khan, Kui Chen, M. Jylh auml, Л В Мурыгина, Thomas A. Dineen, Matthew R. Kaller, Matthew M. Weiss, Stephen A. Hitchcock, Martin Citron, Wenge Zhong, Dean Hickman, Toni Williamson	2012	8
11	Activity-based exposure comparisons among humans and nonclinical safety testing species in an extensively metabolized drug candidate Xenobiotica ·Xiaochun Zhu, J. Greg Slatter, Maurice G. Emery, S. Katoh, Anna Akrami, Xiping Zhang, Dean Hickman, Gary L. Skiles, Raju Subramanian	2012	3
12	In Vitro Metabolism of the Novel, Highly Selective Oral Angiogenesis Inhibitor Motesanib Diphosphate in Preclinical Species and in Humans Drug Metabolism and Disposition ·Chun Li, Lagipoiva Cherelle Jackson, Dean Hickman, Leszek Poppe, 正樹川野, Yihong Zhou, Raju Subramanian, Gondi Kumar, Sekhar Surapaneni	2009	13
13	Structural Characterization and Pharmacodynamic Effects of an Orally Active 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitor Chemical Biology & Drug Design ·Clarence Hale, Murielle M. Véniant, Zhulun Wang, Michelle Chen, U. Settmacher, Rod Cupples, Dean Hickman, Xiaoshan Min, Athena Sudom, Haoda Xu, Richard Yip Je Too, Christopher Fotsch, David J. St. Jean, Minghan Wang	2007	26
14	Potent Inhibition of the Cytochrome P-450 3A-Mediated Human Liver Microsomal Metabolism of a Novel HIV Protease Inhibitor by Ritonavir: A Positive Drug-Drug Interaction Drug Metabolism and Disposition ·Gondi Kumar, Gregorio Alcazar, Ellen Roberts, Liam Pascoe, Dean Hickman, John T. Uchic, Ye Yao, Bruce W. Surber, Samuel Thomas, G. Richard Granneman	1999	133
15	Expression of arylamine N -acetyltransferase in human intestine Gut ·Dean Hickman, Dragos Buculei Buculei, Shivakumar D. Patil, Giannoulis Fakis, Valerie Smelt, Lesley A. Stanley, Mark A. Payton, Jashvant D. Unadkat, Edith Sim	1998	114
16	Enzyme kinetic properties of human recombinant arylamine n-acetyltransferase 2 allotypic variants expressed in Escherichia coli Biochemical Pharmacology ·Dean Hickman, Jairam Palamanda, Jashvant D. Unadkat, Edith Sim	1995	48
17	Arylamine N-acetyltransferase in human red blood cells Biochemical Pharmacology ·Jesús. Brufal Sucarrat, Dean Hickman, Jing Long-hui, Edith Sim	1992	49
18	Genotyping human polymorphic arylamine N-acetyltransferase: identification of new slow allotypic variants Pharmacogenetics ·Dean Hickman, Angela Risch, J. Camilleri, Edith Sim	1992	74
19	N-acetyltransferase polymorphism Biochemical Pharmacology ·Dean Hickman, Luis Santander Cruz	1991	143
20	Effects of dietary Ca/P levels on boars at different developmental phases. Journal of Animal Science ·Dean Hickman, D. C. Mahan	1980	2

About Dean Hickman

Dean Hickman is a scholar working on Pharmacology, Virology, Pharmacology, Pharmaceutical Science and Infectious Diseases, having authored 39 papers that have together received 1.6k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (6 papers), Polyamine Metabolism and Applications (5 papers), Pharmacogenetics and Drug Metabolism (4 papers), Carcinogens and Genotoxicity Assessment (4 papers), 3D Printing in Biomedical Research (3 papers), Hormonal Regulation and Hypertension (3 papers), Drug Transport and Resistance Mechanisms (3 papers) and Computational Drug Discovery Methods (3 papers). The work is most often cited by research in Pharmacology (316 citations), Cancer Research (253 citations), Virology (69 citations), Biochemistry (93 citations) and Pharmaceutical Science (77 citations). Dean Hickman has collaborated with scholars based in United States, United Kingdom and Italy. Frequent co-authors include Edith Sim, Jashvant D. Unadkat, Yi Wang, Giovanni S. Offeddu, Charles G. Knutson, Roger D. Kamm, Angela Risch, Olga A. Morozova, Lesley A. Stanley and Shun Zhang. Their work appears in journals such as Biochemical Pharmacology, Journal of Medicinal Chemistry, Drug Metabolism and Disposition, Antimicrobial Agents and Chemotherapy and Bioorganic & Medicinal Chemistry Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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