Paul C. Orban

10.3k citations

47 papers · 8.2k indexed · 3 hit papers · h-index 26

Molecular Biology top 2%
Cellular and Molecular Neuroscience top 1%
Genetics top 1%
Immunology top 2%
Physiology top 2%

Co-authors: Jamey D. Marth Rüdiger Klein Klaus Rajewsky Horst Mossmann Hua Gu Markus Schubert Megan K. Levings Deborah J. Burks
Topics: Immune Cell Function and Interaction (18 papers)T-cell and B-cell Immunology (14 papers)CAR-T cell therapy research (8 papers)
Cited by: Developmental Neuroscience Endocrine and Autonomic Systems Cellular and Molecular Neuroscience
Journals: Science Proceedings of the National Academy of Sciences Journal of Clinical Investigation
Partner nations: Canada United States Italy

In The Last Decade

Paul C. Orban

45 papers receiving 8.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

2000 1.7k citations Paul C. Orban, Rüdiger Klein et al. profile →
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

1999 1.5k citations Paul C. Orban, Rüdiger Klein et al. profile →
Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

1994 1.1k citations Paul C. Orban et al. profile →

Peers

Countries citing papers authored by Paul C. Orban

Since Specialization

Citations

This map shows the geographic impact of Paul C. Orban's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul C. Orban with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul C. Orban more than expected).

Fields of papers citing papers by Paul C. Orban

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul C. Orban. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul C. Orban. The network helps show where Paul C. Orban may publish in the future.

Co-authorship network of co-authors of Paul C. Orban

This figure shows the co-authorship network connecting the top 25 collaborators of Paul C. Orban. A scholar is included among the top collaborators of Paul C. Orban based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul C. Orban. Paul C. Orban is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell-derived insulin producing cells 2024 ·Molecular Metabolism ·(unknown),Xiao-Qing Dai,Cuilan Nian,Paul C. Orban,C. Bruce Verchere,Patrick E. MacDonald,Francis C. Lynn	1
2	DDIT4L regulates mitochondrial and innate immune activities in early life 2024 ·JCI Insight ·Christina Michalski,(unknown),Ju‐Hee Oh,(unknown),(unknown),(unknown),Martin A. Prusinkiewicz,(unknown),Abdelilah Majdoubi,(unknown),(unknown),Frederic Reicherz,Annette E. Patterson,(unknown),Ashish Sharma,Chinten James Lim,Paul C. Orban,Ramon I. Klein Geltink,Pascal M. Lavoie	2
3	Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes in mice 2023 ·Journal of Clinical Investigation ·Justin A. Spanier,Vivian Fung,(unknown),(unknown),Yixin Chen,(unknown),(unknown),(unknown),(unknown),Jason S. Mitchell,Paul C. Orban,Majid Mojibian,C. Bruce Verchere,Brian T. Fife,Megan K. Levings	33
4	Islet amyloid polypeptide does not suppress pancreatic cancer 2023 ·Molecular Metabolism ·(unknown),Evgeniy Panzhinskiy,Paul C. Orban,Francis C. Lynn,David F. Schaeffer,James D. Johnson,Janel L. Kopp,C. Bruce Verchere	4
5	Flagellin-specific human CAR Tregs for immune regulation in IBD 2022 ·Journal of Autoimmunity ·Dominic A. Boardman,May Q. Wong,William D. Rees,Dan Wu,Megan E. Himmel,Paul C. Orban,Jens Vent‐Schmidt,Nicholas C. Zachos,Theodore S. Steiner,Megan K. Levings	29
6	Neonatal T Helper 17 Responses Are Skewed Towards an Immunoregulatory Interleukin-22 Phenotype 2021 ·Frontiers in Immunology ·Hamid Reza Razzaghian,(unknown),Ashish Sharma,Guilaine K. Boyce,Kelsey Lee,(unknown),Paul C. Orban,Rafick‐Pierre Sékaly,Colin J.D. Ross,Pascal M. Lavoie	14
7	T reg–specific insulin receptor deletion prevents diet-induced and age-associated metabolic syndrome 2020 ·The Journal of Experimental Medicine ·Dan Wu,Chi Kin Wong,Jonathan M. Han,Paul C. Orban,Qing Huang,Jana Gillies,Majid Mojibian,William T. Gibson,Megan K. Levings	31
8	Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in T regulatory cells 2019 ·JCI Insight ·Nicholas A.J. Dawson,Caroline Lamarche,Romy E. Hoeppli,Peter Bergqvist,Vivian Fung,(unknown),Qing Huang,Jana Gillies,Madeleine Speck,Paul C. Orban,(unknown),Majid Mojibian,Megan K. Levings	71
9	Prevention of autoimmune diabetes and islet allograft rejection by beta cell expression of XIAP: Insight into possible mechanisms of local immunomodulation 2018 ·Molecular and Cellular Endocrinology ·Mercè Obach,Azadeh Hosseini‐Tabatabaei,Joel Montané,(unknown),Galina Soukhatcheva,Derek L. Dai,John J. Priatel,Paul C. Orban,C. Bruce Verchere	3
10	Measurement of Pro-Islet Amyloid Polypeptide (1–48) in Diabetes and Islet Transplants 2017 ·The Journal of Clinical Endocrinology & Metabolism ·(unknown),Agnieszka Klimek‐Abercrombie,Yi‐Chun Chen,(unknown),(unknown),Cate Speake,Paul C. Orban,Behzad Najafian,Graydon S. Meneilly,Carla J. Greenbaum,Garth L. Warnock,Constadina Panagiotopoulos,C. Bruce Verchere	32
11	T regulatory cell therapy in transplantation 2012 ·Current Opinion in Organ Transplantation ·Katherine G. MacDonald,Paul C. Orban,Megan K. Levings	19
12	Synaptic dysfunction in progranulin-deficient mice 2011 ·Neurobiology of Disease ·Terri L. Petkau,Scott J. Neal,Austen J. Milnerwood,(unknown),Austin Hill,Paul C. Orban,(unknown),Ge Lu,Howard Feldman,Ian R. Mackenzie,Lynn A. Raymond,Blair R. Leavitt	125
13	Progranulin expression in the developing and adult murine brain 2010 ·The Journal of Comparative Neurology ·Terri L. Petkau,Scott J. Neal,Paul C. Orban,Jessica L. MacDonald,Austin Hill,Ge Lu,Howard Feldman,Ian R. Mackenzie,Blair R. Leavitt	112
14	Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) Controls Activation of Extracellular Signal-Regulated Kinase (ERK) Signaling in the Striatum and Long-Term Behavioral Responses to Cocaine 2009 ·Biological Psychiatry ·Stefania Fasano,(unknown),Paul C. Orban,Emmanuel Valjent,Elena Putignano,Hugo Vara,Tommaso Pizzorusso,Maurizio Giustetto,Bong-June Yoon,Paul D. Soloway,Rafaël Maldonado,Jocelyne Caboche,Riccardo Brambilla	81
15	Cross-species characterization of the ALS2 gene and analysis of its pattern of expression in development and adulthood 2004 ·Neurobiology of Disease ·Rebecca S. Devon,Claudia Schwab,Justin D. Topp,Paul C. Orban,(unknown),Terry D. Pape,(unknown),(unknown),Daniel A. Rogers,François Gros‐Louis,Guy A. Rouleau,Bruce Horazdovsky,Blair R. Leavitt,Michael R. Hayden	23
16	Two ENU-induced mutations in Rasgrf1 and early mouse growth retardation 2003 ·Mammalian Genome ·(unknown),Josephine Peters,Paul C. Orban,Riccardo Brambilla,Chris Graham	31
17	Knockout of ERK1 MAP Kinase Enhances Synaptic Plasticity in the Striatum and Facilitates Striatal-Mediated Learning and Memory 2002 ·Neuron ·Cristina Mazzucchelli,Chiara Vantaggiato,Alessandro Ciamei,Stefania Fasano,Pavel Pakhotin,Wojciech Krężel,Hans Welzl,David P Wolfer,Gilles Pagès,Olga Valverde,Anne Marowsky,(unknown),Paul C. Orban,Rafaël Maldonado,Markus U. Ehrengruber,Vincenzo Cestari,Hans-Peter Lipp,Paul F. Chapman,Jacques Pouysségur,Riccardo Brambilla	376
18	β1-Class Integrins Regulate the Development of Laminae and Folia in the Cerebral and Cerebellar Cortex 2001 ·Neuron ·Diana Graus-Porta,Sandra Blaess,Mathias Senften,Amanda Littlewood-Evans,Caroline H. Damsky,Zhen Huang,Paul C. Orban,Rüdiger Klein,Johannes C. Schittny,Ulrich Müller	474
19	Is the Ras-MAPK signalling pathway necessary for long-term memory formation? 1999 ·Trends in Neurosciences ·Paul C. Orban,Paul F. Chapman,Riccardo Brambilla	166
20	Antibodies to an autostimulatory growth factor (IL-2) or its receptor induce death of leukemogenic cells 1996 ·The Journal of Immunology ·Paul C. Orban,John W. Schrader	2

About Paul C. Orban

Paul C. Orban is a scholar working on Immunology, Cellular and Molecular Neuroscience and Oncology, having authored 47 papers that have together received 8.2k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (18 papers), T-cell and B-cell Immunology (14 papers) and CAR-T cell therapy research (8 papers). The work is most often cited by research in Developmental Neuroscience (600 citations), Endocrine and Autonomic Systems (963 citations) and Cellular and Molecular Neuroscience (1.6k citations). Paul C. Orban has collaborated with scholars based in Canada, United States and Italy. Frequent co-authors include Jamey D. Marth, Rüdiger Klein, Klaus Rajewsky, Horst Mossmann, Hua Gu, Markus Schubert, Megan K. Levings, Deborah J. Burks, Dirk Müller‐Wieland and Wilhelm Krone. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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