Nicholas C. Zachos

7.1k total citations · 3 hit papers
90 papers, 5.3k citations indexed

About

Nicholas C. Zachos is a scholar working on Molecular Biology, Surgery and Genetics. According to data from OpenAlex, Nicholas C. Zachos has authored 90 papers receiving a total of 5.3k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Molecular Biology, 21 papers in Surgery and 21 papers in Genetics. Recurrent topics in Nicholas C. Zachos's work include Ion Transport and Channel Regulation (25 papers), Cancer Cells and Metastasis (14 papers) and Digestive system and related health (12 papers). Nicholas C. Zachos is often cited by papers focused on Ion Transport and Channel Regulation (25 papers), Cancer Cells and Metastasis (14 papers) and Digestive system and related health (12 papers). Nicholas C. Zachos collaborates with scholars based in United States, Netherlands and Canada. Nicholas C. Zachos's co-authors include Mark Donowitz, Olga Kovbasnjuk, Mary K. Estes, Xuhang Li, Julie In, Jennifer Foulke‐Abel, Ming Tse, Tian-E Chen, Sarah E. Blutt and Philip Alex and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Nicholas C. Zachos

90 papers receiving 5.2k citations

Hit Papers

Distinct Cytokine Patterns Identified from Multiplex Prof... 2008 2026 2014 2020 2008 2018 2015 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS-Induced Colitis
    2008 646 citations Philip Alex, Nicholas C. Zachos et al. Inflammatory Bowel Diseases profile →
  2. Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion
    2018 310 citations Nicholas C. Zachos et al. profile →
  3. Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology
    2015 285 citations Sarah E. Blutt, Jennifer Foulke‐Abel et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Nicholas C. Zachos United States 36 2.4k 1.1k 965 877 865 90 5.3k
Jenny K. Gustafsson Sweden 25 3.0k 1.2× 842 0.8× 383 0.4× 961 1.1× 541 0.6× 40 5.6k
Le Shen United States 38 4.1k 1.7× 958 0.9× 647 0.7× 1.2k 1.4× 432 0.5× 69 8.0k
Yun Kyung Lee South Korea 27 3.4k 1.4× 619 0.6× 951 1.0× 542 0.6× 794 0.9× 59 7.1k
Joachim Mankertz Germany 34 3.3k 1.4× 1.8k 1.7× 654 0.7× 1.2k 1.4× 744 0.9× 60 7.3k
Terrence A. Barrett United States 42 1.5k 0.6× 860 0.8× 970 1.0× 679 0.8× 246 0.3× 137 5.1k
Hang Thi Thu Nguyen United States 35 2.3k 0.9× 806 0.7× 537 0.6× 470 0.5× 540 0.6× 98 4.5k
Florian Obermeier Germany 41 1.9k 0.8× 1.5k 1.4× 432 0.4× 882 1.0× 422 0.5× 95 5.7k
Noah W. Palm United States 31 3.2k 1.3× 735 0.7× 347 0.4× 704 0.8× 793 0.9× 54 6.4k
Ingrid B. Renes Netherlands 31 2.0k 0.9× 857 0.8× 388 0.4× 775 0.9× 403 0.5× 72 3.9k
Alexandra W. C. Einerhand Netherlands 41 2.8k 1.2× 1.1k 1.1× 484 0.5× 1.4k 1.5× 542 0.6× 96 5.8k

Countries citing papers authored by Nicholas C. Zachos

Since Specialization
Citations

This map shows the geographic impact of Nicholas C. Zachos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicholas C. Zachos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicholas C. Zachos more than expected).

Fields of papers citing papers by Nicholas C. Zachos

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicholas C. Zachos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicholas C. Zachos. The network helps show where Nicholas C. Zachos may publish in the future.

Co-authorship network of co-authors of Nicholas C. Zachos

This figure shows the co-authorship network connecting the top 25 collaborators of Nicholas C. Zachos. A scholar is included among the top collaborators of Nicholas C. Zachos based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nicholas C. Zachos. Nicholas C. Zachos is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Laky, Karen, Jessica L. Kinard, Ian N. Moore, et al.. (2023). Epithelial-intrinsic defects in TGFβR signaling drive local allergic inflammation manifesting as eosinophilic esophagitis. Science Immunology. 8(79). eabp9940–eabp9940. 20 indexed citations
2.
Bouffi, Carine, Kathryn A. Wikenheiser‐Brokamp, Praneet Chaturvedi, et al.. (2023). In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice. Nature Biotechnology. 41(6). 824–831. 76 indexed citations
3.
Maeda, Keiko, et al.. (2023). Protocol for measuring transcytosis and recycling of IgG in intestinal epithelial Caco-2 cells and primary human intestinal organoids. STAR Protocols. 4(2). 102335–102335. 1 indexed citations
4.
Boardman, Dominic A., May Q. Wong, William D. Rees, et al.. (2022). Flagellin-specific human CAR Tregs for immune regulation in IBD. Journal of Autoimmunity. 134. 102961–102961. 29 indexed citations
5.
Zachos, Nicholas C., et al.. (2021). Optimizing Human Intestinal Enteroids for Environmental Monitoring of Human Norovirus. Food and Environmental Virology. 13(4). 470–484. 13 indexed citations
6.
Zachos, Nicholas C., et al.. (2021). Recovery of Infectious Human Norovirus GII.4 Sydney From Fomites via Replication in Human Intestinal Enteroids. Frontiers in Cellular and Infection Microbiology. 11. 693090–693090. 5 indexed citations
7.
In, Julie, Jianyi Yin, Michèle Doucet, et al.. (2020). Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury. iScience. 23(10). 101618–101618. 9 indexed citations
8.
Pearce, Sarah, et al.. (2018). Intestinal in vitro and ex vivo Models to Study Host-Microbiome Interactions and Acute Stressors. Frontiers in Physiology. 9. 1584–1584. 121 indexed citations
9.
Noël, G., Nicholas W. Baetz, Janet F. Staab, et al.. (2017). A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions. Scientific Reports. 7(1). 45270–45270. 323 indexed citations
10.
In, Julie, Jennifer Foulke‐Abel, Nicholas C. Zachos, et al.. (2015). Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived Colonoids. Cellular and Molecular Gastroenterology and Hepatology. 2(1). 48–62.e3. 194 indexed citations
11.
Singh, Varsha, Jianbo Yang, Nicholas C. Zachos, et al.. (2013). Translating Molecular Physiology of Intestinal Transport Into Pharmacologic Treatment of Diarrhea: Stimulation of Na+ Absorption. Clinical Gastroenterology and Hepatology. 12(1). 27–31. 39 indexed citations
12.
Zhu, Xinjun, Boyoung Cha, Nicholas C. Zachos, et al.. (2011). Elevated Calcium Acutely Regulates Dynamic Interactions of NHERF2 and NHE3 Proteins in Opossum Kidney (OK) Cell Microvilli. Journal of Biological Chemistry. 286(40). 34486–34496. 15 indexed citations
13.
Hartley, Jane, Nicholas C. Zachos, Ban B. Dawood, et al.. (2010). Mutations in TTC37 Cause Trichohepatoenteric Syndrome (Phenotypic Diarrhea of Infancy). Gastroenterology. 138(7). 2388–2398.e2. 96 indexed citations
14.
Alex, Philip, Mei Ye, Nicholas C. Zachos, et al.. (2010). Clcn5 Knockout Mice Exhibit Novel Immunomodulatory Effects and Are More Susceptible to Dextran Sulfate Sodium-Induced Colitis. The Journal of Immunology. 184(7). 3988–3996. 21 indexed citations
15.
Zachos, Nicholas C., Xuhang Li, Olga Kovbasnjuk, et al.. (2009). NHERF3 (PDZK1) Contributes to Basal and Calcium Inhibition of NHE3 Activity in Caco-2BBe Cells. Journal of Biological Chemistry. 284(35). 23708–23718. 31 indexed citations
16.
Zachos, Nicholas C., et al.. (2008). Regulation of Expression of Microvillus Membrane Proteins by Estrogen in Baboon Fetal Ovarian Oocytes1. Biology of Reproduction. 79(6). 1160–1168. 8 indexed citations
17.
Alex, Philip, Nicholas C. Zachos, Thuan T. Nguyen, et al.. (2008). Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS-Induced Colitis. Inflammatory Bowel Diseases. 15(3). 341–352. 646 indexed citations breakdown →
18.
Murtazina, Rakhilya, Olga Kovbasnjuk, Nicholas C. Zachos, et al.. (2007). Tissue-specific Regulation of Sodium/Proton Exchanger Isoform 3 Activity in Na+/H+ Exchanger Regulatory Factor 1 (NHERF1) Null Mice. Journal of Biological Chemistry. 282(34). 25141–25151. 63 indexed citations
19.
Zachos, Nicholas C., Reinhart B. Billiar, Eugene D. Albrecht, & Gerald J. Pepe. (2003). Developmental Regulation of Follicle-Stimulating Hormone Receptor Messenger RNA Expression in the Baboon Fetal Ovary1. Biology of Reproduction. 68(5). 1911–1917. 18 indexed citations
20.
Zachos, Nicholas C., Reinhart B. Billiar, Eugene D. Albrecht, & Gerald J. Pepe. (2002). Developmental Regulation of Baboon Fetal Ovarian Maturation by Estrogen1. Biology of Reproduction. 67(4). 1148–1156. 73 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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