Patrick A. Baeuerle

64.3k total citations · 23 hit papers
290 papers, 52.8k citations indexed

About

Patrick A. Baeuerle is a scholar working on Immunology, Oncology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Patrick A. Baeuerle has authored 290 papers receiving a total of 52.8k indexed citations (citations by other indexed papers that have themselves been cited), including 150 papers in Immunology, 129 papers in Oncology and 102 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Patrick A. Baeuerle's work include Monoclonal and Polyclonal Antibodies Research (102 papers), NF-κB Signaling Pathways (85 papers) and CAR-T cell therapy research (82 papers). Patrick A. Baeuerle is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (102 papers), NF-κB Signaling Pathways (85 papers) and CAR-T cell therapy research (82 papers). Patrick A. Baeuerle collaborates with scholars based in Germany, United States and Switzerland. Patrick A. Baeuerle's co-authors include Ralf Schreck, David Baltimore, Thomas Henkel, P. Rieber, Heike L. Pahl, Peter Kufer, M. Lienhard Schmitz, Christian Kaltschmidt, E. Britta-Mareen Traenckner and Markus Meyer and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Patrick A. Baeuerle

282 papers receiving 51.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Function and Activation of NF-kappaB in the Immune System

1994 4.3k citations Patrick A. Baeuerle et al. profile →
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 3.3k citations Patrick A. Baeuerle et al. profile →
NF-κB: Ten Years After

1996 2.7k citations Patrick A. Baeuerle et al. profile →
IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 1.9k citations Patrick A. Baeuerle et al. profile →
Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 1.4k citations Wulf Dröge, Patrick A. Baeuerle et al. The Journal of Experimental Medicine profile →
Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)

1992 1.2k citations Patrick A. Baeuerle et al. profile →
H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1993 1.2k citations Patrick A. Baeuerle et al. profile →
Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

1993 1.0k citations Patrick A. Baeuerle et al. profile →
The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 950 citations Patrick A. Baeuerle profile →
Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli.

1995 933 citations Patrick A. Baeuerle et al. profile →
The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 829 citations Patrick A. Baeuerle et al. profile →
Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B.

1990 818 citations Patrick A. Baeuerle et al. profile →
Tumor Regression in Cancer Patients by Very Low Doses of a T Cell–Engaging Antibody

2008 798 citations Ralf C. Bargou, Gert Riethmüller et al. profile →
The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.

1991 718 citations Patrick A. Baeuerle et al. profile →
Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

1996 677 citations Korbinian Brand, Sharon Page et al. Journal of Clinical Investigation profile →
A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.

1994 642 citations Patrick A. Baeuerle et al. profile →
Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

1998 607 citations Gerhard Rogler, Korbinian Brand et al. Gastroenterology profile →
Tyrosine Phosphorylation of IκB-α Activates NF-κB without Proteolytic Degradation of IκB-α

1996 597 citations Patrick A. Baeuerle et al. profile →
Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb

2000 582 citations Yvonne Janssen‐Heininger, Matthew E. Poynter et al. Free Radical Biology and Medicine profile →
Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

1995 567 citations Marek Łoś, Patrick A. Baeuerle et al. profile →
Nuclear signalling by tumour-associated antigen EpCAM

2009 565 citations Patrick A. Baeuerle et al. profile →
Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease

1997 532 citations Barbara Kaltschmidt, Patrick A. Baeuerle et al. profile →
NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules.

1997 529 citations Patrick A. Baeuerle et al. profile →

Peers

Countries citing papers authored by Patrick A. Baeuerle

Since Specialization

Citations

This map shows the geographic impact of Patrick A. Baeuerle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick A. Baeuerle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick A. Baeuerle more than expected).

Fields of papers citing papers by Patrick A. Baeuerle

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick A. Baeuerle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick A. Baeuerle. The network helps show where Patrick A. Baeuerle may publish in the future.

Co-authorship network of co-authors of Patrick A. Baeuerle

This figure shows the co-authorship network connecting the top 25 collaborators of Patrick A. Baeuerle. A scholar is included among the top collaborators of Patrick A. Baeuerle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Patrick A. Baeuerle. Patrick A. Baeuerle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	CLN-617 Retains IL2 and IL12 in Injected Tumors to Drive Robust and Systemic Immune-Mediated Antitumor Activity 2024 ·Cancer Immunology Research ·Naveen K. Mehta, Kavya Rakhra, Kristan Meetze, (unknown), Noor Momin, Jason Y.H. Chang, K. Dane Wittrup, Patrick A. Baeuerle, Jennifer S. Michaelson	6
2	CD19-directed T cell–engaging antibodies for the treatment of autoimmune disease 2024 ·The Journal of Experimental Medicine ·Jennifer S. Michaelson, Patrick A. Baeuerle	3
3	CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression 2023 ·Journal for ImmunoTherapy of Cancer ·Kristan Meetze, Naveen K. Mehta, Bochong Li, (unknown), (unknown), Agapitos Patakas, Jennifer S. Michaelson, Patrick A. Baeuerle	11
4	Preclinical Characterization of HPN536, a Trispecific, T-Cell–Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors 2020 ·Clinical Cancer Research ·(unknown), Richard J. Austin, Bryan D. Lemon, Wade H. Aaron, (unknown), (unknown), Susan Dana Jones, (unknown), (unknown), Kenneth G. Sexton, (unknown), Timothy Z. Yu, Patrick A. Baeuerle, Che‐Leung Law, Holger Wesche	35
5	Preclinical Characterization of AMG 330, a CD3/CD33-Bispecific T-Cell–Engaging Antibody with Potential for Treatment of Acute Myelogenous Leukemia 2014 ·Molecular Cancer Therapeutics ·Matthias Friedrich, Anja Henn, Tobias Raum, (unknown), Katja Matthes, (unknown), Joachim Wahl, Patrick Hoffmann, Roman Kischel, (unknown), Jerry W. Slootstra, Patrick A. Baeuerle, Peter Kufer, Benno Rattel	106
6	BiTE Antibodies for Cancer Therapy 2013 ·Journal of Cancer Science & Therapy ·Patrick A. Baeuerle, Roman Kischel	0
7	EpCAM/CD3-Bispecific T-cell Engaging Antibody MT110 Eliminates Primary Human Pancreatic Cancer Stem Cells 2011 ·Clinical Cancer Research ·Michele Cioffi, Jorge Navarro‐Dorado, Patrick A. Baeuerle, Christopher Heeschen	117
8	Bioavailability, pharmacodynamic activity, and anti-tumor efficacy of the CD19/CD3-specific BiTE antibody MEDI-538 (MT103) delivered subcutaneously in animal models 2008 ·Cancer Research ·Kathy Mulgrew, David J. Stewart, (unknown), Wendy L. Trigona, Patricia C. Ryan, (unknown), Ambarish Shah, (unknown), Liang Zhao, Stacy Fuhrmann, Philipp Steiner, Gabriel J. Robbie, Petra Lutterbuese, Bernd Schlereth, Patrick A. Baeuerle, Peter Kufer, Peter A. Kiener, Bahija Jallal, Steven Coats, Scott A. Hammond	2
9	Selective Targeting and Potent Control of Tumor Growth Using an EphA2/CD3-Bispecific Single-Chain Antibody Construct 2007 ·Cancer Research ·Scott A. Hammond, Ralf Lutterbuese, Shannon Roff, Petra Lutterbuese, Bernd Schlereth, Elizabeth Bruckheimer, Michael S. Kinch, Steve Coats, Patrick A. Baeuerle, Peter Kufer, Peter A. Kiener	66
10	Therapeutic window of MuS110, a single-chain antibody construct bispecific for EpCAM (CD326) and CD3 2007 ·Molecular Cancer Therapeutics ·Patrick A. Baeuerle, Maria Amann, Klaus Brischwein, Petra Lutterbuese, Grit Lorenczewski, (unknown), Roman Kischel, Ralf Lutterbuese, Peter Kufer, Bernd Schlereth	3
11	A Subset of Human Dendritic Cells in the T Cell Area of Mucosa-Associated Lymphoid Tissue with a High Potential to Produce TNF-α 2003 ·The Journal of Immunology ·(unknown), Ines Mende, Gustavo Baretton, Andreas Greiner, Wolfgang H. Hartl, Patrick A. Baeuerle, Helmut M. Diepolder	72
12	T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct 2003 ·The Journal of Immunology ·Torsten Dreier, Patrick A. Baeuerle, Iduna Fichtner, M. Grün, Bernd Schlereth, Grit Lorenczewski, Peter Kufer, Ralf Lutterbüse, Gert Riethmüller, P. Gjörstrup, Ralf C. Bargou	155
13	Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb breakdown → 2000 ·Free Radical Biology and Medicine ·Yvonne Janssen‐Heininger, Matthew E. Poynter, Patrick A. Baeuerle	582
14	Antioxidant and redox regulation of genes 1999 ·Academic Press eBooks ·Chandan K. Sen, Helmut Sies, Patrick A. Baeuerle	71
15	Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa breakdown → 1998 ·Gastroenterology ·Gerhard Rogler, Korbinian Brand, Daniela Vogl, Sharon Page, Robert Hofmeister, Tilo Andus, Ruth Knuechel, Patrick A. Baeuerle, Jürgen Schölmerich, Volker Groß	607
16	trans -Activation of the HIV Type 1 Promoter by 7,8-Dihydroneopterin in Vitro 1997 ·AIDS Research and Human Retroviruses ·Gottfried Baier, Dietmar Fuchs, Robert Zangerle, Patrick A. Baeuerle, Ernst R. Werner, Friedrich Fresser, Florian Überall, Helmut Wächter	14
17	Activation of NF-kB by nerve growth factor through the neurotrophin receptor p75 1996 ·PUB – Publications at Bielefeld University (Bielefeld University) ·(unknown), Christian Kaltschmidt, Barbara Kaltschmidt, Nina Offenhäuser, (unknown), Patrick A. Baeuerle, Yves‐Alain Barde	3
18	Transcription factor NF-kB/Rel is activated in the atherosclerotic lesion. 1996 ·Journal of Clinical Investigation ·Korbinian Brand, Gerhard Rogler, Andreas Bartsch, Ruth Knuechel, Michael J. Page, Patrick A. Baeuerle, D. Neumeier, Christian Kaltschmidt	11
19	Environmental stresses and nutrients 1995 ·Birkhäuser eBooks ·Patrick A. Baeuerle	2
20	Hydrogen peroxide as a potent activator of T lymphocyte functions 1995 ·European Journal of Immunology ·Marek Łoś, Wulf Dröge, Kirstin Stricker, Patrick A. Baeuerle, Klaus Schulze‐Osthoff	172

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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