Owen W. Griffith

21.0k total citations · 9 hit papers
142 papers, 18.2k citations indexed

About

Owen W. Griffith is a scholar working on Biochemistry, Molecular Biology and Physiology. According to data from OpenAlex, Owen W. Griffith has authored 142 papers receiving a total of 18.2k indexed citations (citations by other indexed papers that have themselves been cited), including 68 papers in Biochemistry, 51 papers in Molecular Biology and 46 papers in Physiology. Recurrent topics in Owen W. Griffith's work include Nitric Oxide and Endothelin Effects (37 papers), Sulfur Compounds in Biology (37 papers) and Amino Acid Enzymes and Metabolism (28 papers). Owen W. Griffith is often cited by papers focused on Nitric Oxide and Endothelin Effects (37 papers), Sulfur Compounds in Biology (37 papers) and Amino Acid Enzymes and Metabolism (28 papers). Owen W. Griffith collaborates with scholars based in United States, France and Canada. Owen W. Griffith's co-authors include A Meister, Dennis J. Stuehr, A Meister, Robert G. Kilbourn, Roberto Levi, Steven S. Gross, Alton Meister, Kazuo Aisaka, C F Nathan and Robert F. Lodato and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Circulation.

In The Last Decade

Owen W. Griffith

141 papers receiving 17.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1980 4.2k citations Owen W. Griffith profile →
Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).

1979 1.5k citations Owen W. Griffith et al. Journal of Biological Chemistry profile →
Nitric Oxide Synthases: Properties and Catalytic Mechanism

1995 1.1k citations Owen W. Griffith, Dennis J. Stuehr profile →
Biologic and pharmacologic regulation of mammalian glutathione synthesis

1999 992 citations Owen W. Griffith profile →
Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis.

1982 628 citations Owen W. Griffith Journal of Biological Chemistry profile →
Glutathione: interorgan translocation, turnover, and metabolism.

1979 526 citations Owen W. Griffith, A Meister profile →
NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide.

1990 520 citations Robert G. Kilbourn, Steven S. Gross et al. profile →
Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis

1990 455 citations Robert G. Kilbourn, Steven S. Gross et al. Biochemical and Biophysical Research Communications profile →
Origin and turnover of mitochondrial glutathione.

1985 410 citations Owen W. Griffith, A Meister profile →

Peers

Countries citing papers authored by Owen W. Griffith

Since Specialization

Citations

This map shows the geographic impact of Owen W. Griffith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Owen W. Griffith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Owen W. Griffith more than expected).

Fields of papers citing papers by Owen W. Griffith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Owen W. Griffith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Owen W. Griffith. The network helps show where Owen W. Griffith may publish in the future.

Co-authorship network of co-authors of Owen W. Griffith

This figure shows the co-authorship network connecting the top 25 collaborators of Owen W. Griffith. A scholar is included among the top collaborators of Owen W. Griffith based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Owen W. Griffith. Owen W. Griffith is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study 2025 ·Frontiers in Neurology ·Owen W. Griffith, Xiaoxiao Bai, Alexa E. Walter, Michael Gay, (unknown), Wayne J. Sebastianelli, Linda Papa, Semyon Slobounov	0
2	Perspective: supplementation with macular pigment carotenoids with respect to brain injury 2025 ·Discover Medicine ·(unknown), Owen W. Griffith, Linda Papa, Lacy M. Alexander, Semyon Slobounov	1
3	Glutathione Synthesis in Streptococcus agalactiae 2005 ·Journal of Biological Chemistry ·Blythe E. Janowiak, Owen W. Griffith	95
4	Structural Characterization and Kinetics of Nitric-oxide Synthase Inhibition by Novel N5-(Iminoalkyl)- and N5-(Iminoalkenyl)-ornithines 2003 ·Journal of Biological Chemistry ·Lynn E. Bretscher, Huiying Li, T.L. Poulos, Owen W. Griffith	32
5	Glutaminase and the Control of Airway pH: Yet Another Problem for the Asthmatic Lung? 2002 ·American Journal of Respiratory and Critical Care Medicine ·Owen W. Griffith	23
6	Implications for Isoform-selective Inhibitor Design Derived from the Binding Mode of Bulky Isothioureas to the Heme Domain of Endothelial Nitric-oxide Synthase 2001 ·Journal of Biological Chemistry ·C.S. Raman, Huiying Li, Pavel Martásek, (unknown), Owen W. Griffith, B.S.S. Masters, T.L. Poulos	24
7	The Enzymes of Glutathione Synthesis: γ‐Glutamylcysteine Synthetase 1999 ·Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects ·Owen W. Griffith, Ríona Mulcahy	222
8	l-Arginine Binding to Nitric-oxide Synthase 1999 ·Journal of Biological Chemistry ·(unknown), (unknown), Owen W. Griffith	40
9	Inhibition of endothelial cell amino acid transport System y+ by arginine analogs that inhibit nitric oxide synthase 1997 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·Kelly McDonald, (unknown), Mary E. Handlogten, Edward R. Block, Owen W. Griffith, R. Donald Allison, Michael S. Kilberg	23
10	Design of nitric oxide synthase inhibitors and their use to reverse hypotension associated with cancer immunotherapy 1997 ·Advances in Enzyme Regulation ·Owen W. Griffith, Robert G. Kilbourn	12
11	Nitric oxide synthase inhibitors: Amino acids 1996 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Owen W. Griffith, Robert G. Kilbourn	100
12	NO in septic shock: Good, bad or ugly? Learning from iNOS knockouts 1996 ·Trends in Microbiology ·Steven S. Gross, Robert G. Kilbourn, Owen W. Griffith	23
13	S-Alkyl-l-thiocitrullines 1995 ·Journal of Biological Chemistry ·Narayanan Krishnaswamy, (unknown), Kirk McMillan, Robert G. Kilbourn, Michael A. Hayward, Bettie Sue Siler Masters, Owen W. Griffith	72
14	N sup G-methyl-L-arginine, an inhibitor of nitric oxide synthase, reverses interleukin-2-induced hypotension 1995 ·Critical Care Medicine ·Robert G. Kilbourn, Gustavo Fonseca, Owen W. Griffith, Michael S. Ewer, Kristen Price, (unknown), (unknown), Christopher J. Logothetis	45
15	Effect of carnitine acetyltransferase inhibition on rat hepatocyte metabolism 1991 ·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Eric P. Brass, Richard D. Gandour, Owen W. Griffith	6
16	Macrophage and endothelial cell nitric oxide synthesis: Cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine 1990 ·Biochemical and Biophysical Research Communications ·Steven S. Gross, Dennis J. Stuehr, Kazuo Aisaka, Eric Jaffe, Roberto Levi, Owen W. Griffith	242
17	Lack of Effect of Glutathione Depletion by L-Buthionine-SR-Sulfoximine on Gentamicin Nephrotoxicity in Rats 1990 ·Pharmacology ·Dafang Wu, Owen W. Griffith, Marcus M. Reidenberg	8
18	Buthionine sulfoximine-mediated depletion of glutathione in intracranial human glioma-derived xenografts 1988 ·Biochemical Pharmacology ·Stephen X. Skapek, O. Michael Colvin, Owen W. Griffith, Dennis R. Groothuis, Edward V. Colapinto, Yisheng Lee, John Hilton, Gertrude B. Elion, Darell D. Bigner, (unknown)	18
19	Inhibition of glutathione synthesis as a chemotherapeutic strategy for trypanosomiasis. 1981 ·The Journal of Experimental Medicine ·Bradley A. Arrick, Owen W. Griffith, Anthony Cerami	119
20	Effects of methionine sulfoximine analogs on the synthesis of glutamine and glutathione: possible chemotherapeutic implications. 1979 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·A Meister, Owen W. Griffith	55

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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