Edward R. Block

8.8k total citations · 2 hit papers
149 papers, 7.2k citations indexed

About

Edward R. Block is a scholar working on Physiology, Molecular Biology and Biochemistry. According to data from OpenAlex, Edward R. Block has authored 149 papers receiving a total of 7.2k indexed citations (citations by other indexed papers that have themselves been cited), including 67 papers in Physiology, 57 papers in Molecular Biology and 36 papers in Biochemistry. Recurrent topics in Edward R. Block's work include Nitric Oxide and Endothelin Effects (58 papers), Eicosanoids and Hypertension Pharmacology (19 papers) and Pulmonary Hypertension Research and Treatments (15 papers). Edward R. Block is often cited by papers focused on Nitric Oxide and Endothelin Effects (58 papers), Eicosanoids and Hypertension Pharmacology (19 papers) and Pulmonary Hypertension Research and Treatments (15 papers). Edward R. Block collaborates with scholars based in United States, Australia and Canada. Edward R. Block's co-authors include Jawaharlal M. Patel, Sergey Zharikov, Yunchao Su, Richard J. Johnson, Takahiko Nakagawa, Karina Krotova, S. I. Zharikov, John E. Bennett, J. M. Patel and Hanbo Hu and has published in prestigious journals such as Journal of Biological Chemistry, Annals of Internal Medicine and The Journal of Immunology.

In The Last Decade

Edward R. Block

148 papers receiving 6.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hyperuricemia induces endothelial dysfunction

2005 974 citations Sergey Zharikov, Karina Krotova et al. profile →
A causal role for uric acid in fructose-induced metabolic syndrome

2005 854 citations Hanbo Hu, Sergey Zharikov et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Edward R. Block United States	45	2.1k	2.1k	1.5k	1.2k	1.1k	149	7.2k
Reiko Inagi Japan	58	2.9k 1.4×	1.4k 0.7×	2.7k 1.9×	1.4k 1.2×	1.1k 1.0×	194	10.1k
David A. Power Australia	44	2.4k 1.1×	1.5k 0.7×	1.5k 1.0×	639 0.5×	444 0.4×	187	7.0k
J Brett United States	35	3.2k 1.5×	2.4k 1.1×	764 0.5×	822 0.7×	1.2k 1.1×	45	11.8k
János G. Filep Canada	59	2.9k 1.4×	1.8k 0.9×	729 0.5×	1.4k 1.2×	366 0.3×	196	9.0k
D Stern United States	57	4.9k 2.3×	2.6k 1.2×	775 0.5×	1.4k 1.2×	1.1k 1.0×	92	16.6k
Tom Teerlink Netherlands	55	2.3k 1.1×	3.2k 1.5×	804 0.6×	1.1k 0.9×	432 0.4×	242	10.1k
George F. Schreiner United States	56	4.2k 2.0×	1.2k 0.6×	3.1k 2.1×	975 0.8×	1.2k 1.1×	139	11.3k
Gregory B. Bulkley United States	49	1.4k 0.7×	1.4k 0.7×	703 0.5×	1.7k 1.5×	1.1k 1.0×	113	8.4k
Berthold Hocher Germany	53	2.2k 1.0×	1.8k 0.9×	1.7k 1.1×	559 0.5×	886 0.8×	355	9.4k
Pravin C. Singhal United States	45	2.2k 1.0×	812 0.4×	2.1k 1.4×	664 0.6×	590 0.6×	301	7.4k

Countries citing papers authored by Edward R. Block

Since Specialization

Citations

This map shows the geographic impact of Edward R. Block's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward R. Block with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward R. Block more than expected).

Fields of papers citing papers by Edward R. Block

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward R. Block. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward R. Block. The network helps show where Edward R. Block may publish in the future.

Co-authorship network of co-authors of Edward R. Block

This figure shows the co-authorship network connecting the top 25 collaborators of Edward R. Block. A scholar is included among the top collaborators of Edward R. Block based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edward R. Block. Edward R. Block is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Krotova, Karina, Jawaharlal M. Patel, Edward R. Block, & Sergey Zharikov. (2010). Endothelial arginase II responds to pharmacological inhibition by elevation in protein level. Molecular and Cellular Biochemistry. 343(1-2). 211–216. 11 indexed citations

Kondrikov, Dmitry, Fábio V. Fonseca, Shawn Elms, et al.. (2009). β-Actin Association with Endothelial Nitric-oxide Synthase Modulates Nitric Oxide and Superoxide Generation from the Enzyme. Journal of Biological Chemistry. 285(7). 4319–4327. 43 indexed citations

Aldonytė, Rūta, Bilian Jin, Mark Brantly, et al.. (2008). Endothelial Alpha-1-Antitrypsin Attenuates Cigarette Smoke Induced ApoptosisIn Vitro. COPD Journal of Chronic Obstructive Pulmonary Disease. 5(3). 153–162. 40 indexed citations

Zharikov, Sergey, Karina Krotova, Hanbo Hu, et al.. (2008). Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells. American Journal of Physiology-Cell Physiology. 295(5). C1183–C1190. 195 indexed citations

Li, Liuzhe, Jianliang Zhang, Bilian Jin, Edward R. Block, & Jawaharlal M. Patel. (2007). Nitric oxide upregulation of caspase-8 mRNA expression in lung endothelial cells: role of JAK2/STAT-1 signaling. Molecular and Cellular Biochemistry. 305(1-2). 71–77. 12 indexed citations

Zharikov, Sergey, et al.. (2007). Uric acid reduces nitric oxide (NO) bioavailability in endothelial cells by activating the L-arginine/arginase pathway. The FASEB Journal. 21(6). 10–1. 1 indexed citations

Krotova, Karina, Hanbo Hu, Shen‐Ling Xia, et al.. (2006). Peptides modified by myristoylation activate eNOS in endothelial cells through Akt phosphorylation. British Journal of Pharmacology. 148(5). 732–740. 22 indexed citations

Li, Liuzhe, Jianliang Zhang, Edward R. Block, & Jawaharlal M. Patel. (2004). Nitric oxide-modulated marker gene expression of signal transduction pathways in lung endothelial cells. Nitric Oxide. 11(4). 290–297. 12 indexed citations

Zhang, Jianliang, Bilian Jin, Liuzhe Li, Edward R. Block, & Jawaharlal M. Patel. (2004). Nitric oxide-induced persistent inhibition and nitrosylation of active site cysteine residues of mitochondrial cytochrome-c oxidase in lung endothelial cells. American Journal of Physiology-Cell Physiology. 288(4). C840–C849. 85 indexed citations

10.

Kahlos, Katriina, Jianliang Zhang, Edward R. Block, & Jawaharlal M. Patel. (2003). Thioredoxin restores nitric oxide-induced inhibition of protein kinase C activity in lung endothelial cells. Molecular and Cellular Biochemistry. 254(1-2). 47–54. 33 indexed citations

11.

Su, Yunchao & Edward R. Block. (2000). Phenylarsine oxide inhibits nitric oxide synthase in pulmonary artery endothelial cells. Free Radical Biology and Medicine. 28(2). 167–173. 9 indexed citations

12.

Patel, J. M., et al.. (1996). Nitric Oxide-Induced Inhibition of Lung Endothelial Cell Nitric Oxide Synthase via Interaction with Allosteric Thiols: Role of Thioredoxin in Regulation of Catalytic Activity. American Journal of Respiratory Cell and Molecular Biology. 15(3). 410–419. 72 indexed citations

13.

Su, Yunchao & Edward R. Block. (1996). Acute hypoxia increases intracellular L-arginine content in cultured porcine pulmonary artery endothelial cells. Journal of Cellular Physiology. 167(2). 349–353. 13 indexed citations

14.

Patel, J. M. & Edward R. Block. (1995). Sulfhydryl-Disulfide Modulation and the Role of Disulfide Oxidoreductases in Regulation of the Catalytic Activity of Nitric Oxide Synthase in Pulmonary Artery Endothelial Cells. American Journal of Respiratory Cell and Molecular Biology. 13(3). 352–359. 47 indexed citations

15.

Hart, M., et al.. (1990). Fatty acids alter the susceptibility of cultured endothelial cells to oxidant injury. 1 indexed citations

16.

Block, Edward R., et al.. (1990). Hypoxia Directly Increases Serotonin Transport by Porcine Pulmonary Artery Endothelial Cell Plasma Membrane Vesicles. American Journal of Respiratory Cell and Molecular Biology. 3(4). 363–367. 19 indexed citations

17.

Smith, L.M., Nancy P. Mendenhall, Michael J. Cicale, et al.. (1989). Results of a prospective study evaluating the effects of mantle irradiation on pulmonary function. International Journal of Radiation Oncology*Biology*Physics. 16(1). 79–84. 66 indexed citations

18.

Block, Edward R., et al.. (1988). Plasma membrane fluidity measurements in intact endothelial cells: Effect of hyperoxia on fluorescence anisotropies of 1‐[4‐(trimethylamino)phenyl]‐6‐phenyl hexa‐1,3,5‐triene. Journal of Cellular Physiology. 134(1). 117–123. 44 indexed citations

19.

Block, Edward R. & F J Schoen. (1982). Depression of serotonin uptake by rat lungs exposed to paraquat.. Journal of Pharmacology and Experimental Therapeutics. 221(1). 254–260. 10 indexed citations

20.

Block, Edward R., et al.. (1978). Effect of oxygen exposure on lung clearance of amines. Lung. 155(1). 287–295. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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