Misaki Sekiguchi

1.8k total citations · 2 hit papers
19 papers, 1.4k citations indexed

About

Misaki Sekiguchi is a scholar working on Physiology, Molecular Biology and Pharmacology. According to data from OpenAlex, Misaki Sekiguchi has authored 19 papers receiving a total of 1.4k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Physiology, 8 papers in Molecular Biology and 5 papers in Pharmacology. Recurrent topics in Misaki Sekiguchi's work include Alzheimer's disease research and treatments (12 papers), Cholinesterase and Neurodegenerative Diseases (4 papers) and Autophagy in Disease and Therapy (4 papers). Misaki Sekiguchi is often cited by papers focused on Alzheimer's disease research and treatments (12 papers), Cholinesterase and Neurodegenerative Diseases (4 papers) and Autophagy in Disease and Therapy (4 papers). Misaki Sekiguchi collaborates with scholars based in Japan, Sweden and United Kingdom. Misaki Sekiguchi's co-authors include Takaomi C. Saido, Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki, Hahn-Jun Lee, Kaori Watanabe, Yoko Sekine‐Aizawa, Emi Hama, Takashi Saito and Per Nilsson and has published in prestigious journals such as Journal of Biological Chemistry, Nature Medicine and Nature Communications.

In The Last Decade

Misaki Sekiguchi

19 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification of the major Aβ1–42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition

2000 714 citations Nobuhisa Iwata, Satoshi Tsubuki et al. Nature Medicine profile →
Aβ Secretion and Plaque Formation Depend on Autophagy

2013 386 citations Per Nilsson, Misaki Sekiguchi et al. Cell Reports profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Misaki Sekiguchi Japan	11	964	531	287	272	262	19	1.4k
Patricia Spilman United States	15	767 0.8×	695 1.3×	362 1.3×	198 0.7×	282 1.1×	26	1.5k
Charlotte Bauer France	15	733 0.8×	529 1.0×	154 0.5×	241 0.9×	188 0.7×	20	1.1k
Kerri J. Kinghorn United Kingdom	17	525 0.5×	604 1.1×	213 0.7×	187 0.7×	153 0.6×	23	1.4k
Sarah Mueller-Steiner United States	5	674 0.7×	393 0.7×	240 0.8×	158 0.6×	129 0.5×	6	1.2k
Suzanne J. Randle United Kingdom	14	470 0.5×	639 1.2×	242 0.8×	162 0.6×	132 0.5×	20	1.1k
Lotta Agholme Sweden	15	592 0.6×	537 1.0×	121 0.4×	264 1.0×	130 0.5×	24	1.2k
Kunié Ando Belgium	25	1.1k 1.1×	869 1.6×	124 0.4×	512 1.9×	229 0.9×	57	1.8k
Eva Czirr United States	14	635 0.7×	391 0.7×	145 0.5×	149 0.5×	160 0.6×	21	1.2k
Kazuchika Nishitsuji Japan	22	770 0.8×	795 1.5×	90 0.3×	217 0.8×	166 0.6×	60	1.6k
Fiona Pickford United States	8	1.1k 1.2×	546 1.0×	712 2.5×	244 0.9×	308 1.2×	8	1.8k

Countries citing papers authored by Misaki Sekiguchi

Since Specialization

Citations

This map shows the geographic impact of Misaki Sekiguchi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Misaki Sekiguchi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Misaki Sekiguchi more than expected).

Fields of papers citing papers by Misaki Sekiguchi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Misaki Sekiguchi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Misaki Sekiguchi. The network helps show where Misaki Sekiguchi may publish in the future.

Co-authorship network of co-authors of Misaki Sekiguchi

This figure shows the co-authorship network connecting the top 25 collaborators of Misaki Sekiguchi. A scholar is included among the top collaborators of Misaki Sekiguchi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Misaki Sekiguchi. Misaki Sekiguchi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

Hashimoto, Shoko, Naoto Watamura, Misaki Sekiguchi, et al.. (2025). The Role of Neprilysin and Insulin-Degrading Enzyme in the Etiology of Sporadic Alzheimer's Disease. Journal of Neuroscience. 45(23). e2152242025–e2152242025. 2 indexed citations

Nagata, Kenichi, Shoko Hashimoto, Yukio Matsuba, et al.. (2024). Tau Accumulation Induces Microglial State Alterations in Alzheimer's Disease Model Mice. eNeuro. 11(12). ENEURO.0260–24.2024. 5 indexed citations

Mihira, Naomi, Misaki Sekiguchi, Luca Sartori, et al.. (2024). The Icelandic Mutation (APP-A673T) Is Protective against Amyloid Pathology In Vivo. Journal of Neuroscience. 44(47). e0223242024–e0223242024. 3 indexed citations

Iwata, Nobuhisa, Satoshi Tsubuki, Misaki Sekiguchi, et al.. (2024). Metabolic resistance of Aβ3pE-42, a target epitope of the anti-Alzheimer therapeutic antibody, donanemab. Life Science Alliance. 7(12). e202402650–e202402650. 2 indexed citations

Watamura, Naoto, Kaori Sato, Naoko Kamano, et al.. (2022). An isogenic panel of App knock-in mouse models: Profiling β-secretase inhibition and endosomal abnormalities. Science Advances. 8(23). eabm6155–eabm6155. 11 indexed citations

Sato, Kaori, Naoto Watamura, Naomi Mihira, et al.. (2021). A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid β peptide. Journal of Biological Chemistry. 297(3). 101004–101004. 19 indexed citations

Schedin‐Weiss, Sophia, Per Nilsson, Anna Matton, et al.. (2020). Proteomics Time-Course Study of App Knock-In Mice Reveals Novel Presymptomatic Aβ42-Induced Pathways to Alzheimer’s Disease Pathology. Journal of Alzheimer s Disease. 75(1). 321–335. 12 indexed citations

Sasaguri, Hiroki, Kenichi Nagata, Misaki Sekiguchi, et al.. (2018). Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID. Nature Communications. 9(1). 2892–2892. 53 indexed citations

Sekiguchi, Misaki, Atsushi Yamamoto, Sen‐ichi Aizawa, et al.. (2018). Separation of Synephrine Enantiomers in Citrus Fruits by a Reversed Phase HPLC after Chiral Precolumn Derivatization. Analytical Sciences. 35(4). 407–412. 10 indexed citations

10.

Nilsson, Per, Misaki Sekiguchi, Bengt Winblad, et al.. (2015). Loss of neprilysin alters protein expression in the brain of Alzheimer's disease model mice. PROTEOMICS. 15(19). 3349–3355. 11 indexed citations

11.

Nilsson, Per, Misaki Sekiguchi, Takumi Akagi, et al.. (2014). Autophagy-Related Protein 7 Deficiency in Amyloid β (Aβ) Precursor Protein Transgenic Mice Decreases Aβ in the Multivesicular Bodies and Induces Aβ Accumulation in the Golgi. American Journal Of Pathology. 185(2). 305–313. 83 indexed citations

12.

Nilsson, Per, Misaki Sekiguchi, Takumi Akagi, et al.. (2014). P1‐076: MECHANISMS OF AUTOPHAGY‐MEDIATED AB SECRETION. Alzheimer s & Dementia. 10(4S_Part_8). 1 indexed citations

13.

Nilsson, Per, Misaki Sekiguchi, Yukio Matsuba, et al.. (2013). Aβ Secretion and Plaque Formation Depend on Autophagy. Cell Reports. 5(1). 61–69. 386 indexed citations breakdown →

14.

Iwata, Nobuhisa, Misaki Sekiguchi, Masashi Asai, et al.. (2013). Global brain delivery of neprilysin gene by intravascular administration of AAV vector in mice. Scientific Reports. 3(1). 1472–1472. 79 indexed citations

15.

Nilsson, Per, Nobuhisa Iwata, Misaki Sekiguchi, Takashi Saito, & Takaomi C. Saido. (2012). P4‐014: Autophagy deficiency increases beta‐amyloid pathology and memory impairment in APP transgenic mice. Alzheimer s & Dementia. 8(4S_Part_17). 1 indexed citations

16.

Saito, Takashi, Nobuhisa Iwata, Yoshie Takaki, et al.. (2004). P4-174 Neuropeptides regulate brain amyloid beta levels through a modulation of neprilysin activity. Neurobiology of Aging. 25. S525–S525. 1 indexed citations

17.

Higuchi, Makoto, Jiro Takano, Nobuhisa Iwata, Misaki Sekiguchi, & Takaomi C. Saido. (2004). P1-234 Contribution of calpains and caspases to Abeta-induced neuritic and synaptic pathologies in Alzheimer's disease patients and amyloid precursor protein transgenic mice. Neurobiology of Aging. 25. S163–S163. 2 indexed citations

18.

Watanabe, Kiyotaka, et al.. (2001). Iron Content of Rat Serum Ferritin.. Journal of Veterinary Medical Science. 63(5). 587–589. 27 indexed citations

19.

Iwata, Nobuhisa, Satoshi Tsubuki, Yoshie Takaki, et al.. (2000). Identification of the major Aβ1–42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition. Nature Medicine. 6(2). 143–150. 714 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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