Nicolas Le Novère

25.0k citations

138 papers · 11.0k indexed · 2 hit papers · h-index 53

Impact in

Cellular and Molecular Neuroscience top 0.5%
- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
Molecular Biology top 0.5%
- Nicotinic Acetylcholine Receptors Study
- Receptor Mechanisms and Signaling
- Gene Regulatory Network Analysis
- Microbial Metabolic Engineering and Bioproduction
- Bioinformatics and Genomic Networks
- Ion channel regulation and function

Papers in

Information Systems and Management 15
- Scientific Computing and Data Management 15
Molecular Biology 124
- Gene Regulatory Network Analysis 50
- Bioinformatics and Genomic Networks 46
- Microbial Metabolic Engineering and Bioproduction 41
- Receptor Mechanisms and Signaling 26
- Nicotinic Acetylcholine Receptors Study 25
- Biomedical Text Mining and Ontologies 19

Co-authors: Jean‐Pierre Changeux Pierre‐Jean Corringer Michèle Zoli Melanie I. Stefan Camille Laibe Clément Léna Vijayalakshmi Chelliah Michael Hucka
Journals: Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics (14 papers)BMC Systems Biology (10 papers)Nucleic Acids Research (8 papers)Bioinformatics (8 papers)BMC Bioinformatics (6 papers)
Partner nations: United Kingdom United States France

In The Last Decade

Nicolas Le Novère

138 papers receiving 10.7k citations

Hit Papers

align trajectories log scale

BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems 2005 · 517 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2005 Nucleic Acids Research
2000 The Annual Review of Pharmacology and Toxicology

Peers

Countries citing papers authored by Nicolas Le Novère

Since Specialization

Citations

This map shows the geographic impact of Nicolas Le Novère's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicolas Le Novère with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicolas Le Novère more than expected).

Fields of papers citing papers by Nicolas Le Novère

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicolas Le Novère. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicolas Le Novère. The network helps show where Nicolas Le Novère may publish in the future.

Co-authors

The 25 scholars most cited alongside Nicolas Le Novère, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Nicolas Le Novère Line = papers co-authored together Nicolas Le Novère links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Neurogranin stimulates Ca2+/calmodulin-dependent kinase II by suppressing calcineurin activity at specific calcium spike frequencies PLoS Computational Biology ·Lu Li, Massimo Lai, Stephen Cole, Nicolas Le Novère, Stuart J. Edelstein	2020	21
2	Multi-Omics and Genome-Scale Modeling Reveal a Metabolic Shift During C. elegans Aging Frontiers in Molecular Biosciences ·Janna Hastings, Abraham Mains, Bhupinder Virk, Nicolás Rodríguez, Sharlene Murdoch, Juliette Pearce, Sven Bergmann, Nicolas Le Novère, Olivia Casanueva	2019	40
3	Community-driven roadmap for integrated disease maps Briefings in Bioinformatics ·Marek Ostaszewski, Stephan Gebel, Inna Kuperstein, Alexander Mazein, Andreï Zinovyev, Uğur Doğrusöz, Jan Hasenauer, Ronan M. T. Fleming, Nicolas Le Novère, Piotr Gawron, Thomas Ligon, Anna Niarakis, David Nickerson, Daniel Weindl, Rudi Balling, Emmanuel Barillot, Charles Auffray, Reinhard Schneider	2018	37
4	Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition eLife ·Veronica Musante, Lu Li, Jean Kanyo, TuKiet T. Lam, Christopher M. Colangelo, Shuk Kei Cheng, A. Harrison Brody, Paul Greengard, Nicolas Le Novère, Angus C. Nairn	2017	21
5	BioModels: expanding horizons to include more modelling approaches and formats Nucleic Acids Research ·Mihai Glont, Tung V. N. Nguyen, Martin Graesslin, Robert Hälke, Ali Raza, Jochen Schramm, Sarala Wimalaratne, Varun B. Kothamachu, Nicolás Rodríguez, Maciej J. Swat, Roland Eils, Camille Laibe, Rahuman S. Malik‐Sheriff, Vijayalakshmi Chelliah, Nicolas Le Novère, Henning Hermjakob	2017	55
6	Systems Biology Markup Language (SBML) Level 2 Version 5: Structures and Facilities for Model Definitions Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics ·Michael Hucka, Frank Bergmann, Andreas Dräger, Stefan Hoops, Sarah Keating, Nicolas Le Novère, Chris J. Myers, Brett G. Olivier, Sven Sahle, James C. Schaff, Lucian P. Smith, Dagmar Waltemath, Darren J. Wilkinson	2015	5
7	Perturbations of PIP3 signalling trigger a global remodelling of mRNA landscape and reveal a transcriptional feedback loop Nucleic Acids Research ·Vladimir Yu Kiselev, Véronique Juvin, Mouhannad Malek, Nicholas M. Luscombe, Phillip T. Hawkins, Nicolas Le Novère, Len Stephens	2015	15
8	Quantitative and logic modelling of molecular and gene networks Nature Reviews Genetics ·Nicolas Le Novère	2015	287
9	Mathematical Models of Pluripotent Stem Cells: At the Dawn of Predictive Regenerative Medicine Methods in molecular biology ·Pınar Pir, Nicolas Le Novère	2015	14
10	Modulation of Calmodulin Lobes by Different Targets: An Allosteric Model with Hemiconcerted Conformational Transitions PLoS Computational Biology ·Massimo Lai, Denis Brun, Stuart J. Edelstein, Nicolas Le Novère	2015	23
11	Considerations of graph-based concepts to manage of computational biology models and associated simulations. GI-Jahrestagung ·Ron Henkel, Nicolas Le Novère, Olaf Wolkenhauer, Dagmar Waltemath	2012	6
12	Wanting what we don't want to want: Representing Addiction in Interoperable Bio-Ontologies PhilPapers (PhilPapers Foundation) ·Janna Hastings, Nicolas Le Novère, Werner Ceusters, Kevin Mulligan, Barry Smith	2012	1
13	Delivering 'Cool URIs' That Do Not Change. Nick Juty, Nicolas Le Novère, Henning Hermjakob, Camille Laibe	2012	1
14	Identifiers.org and MIRIAM Registry: community resources to provide persistent identification Nucleic Acids Research ·Nick Juty, Nicolas Le Novère, Camille Laibe	2011	124
15	Ligand Depletion in vivo Modulates the Dynamic Range and Cooperativity of Signal Transduction PLoS ONE ·Stuart J. Edelstein, Melanie I. Stefan, Nicolas Le Novère	2010	14
16	Comparative models of P2X2 receptor support inter-subunit ATP-binding sites Biochemical and Biophysical Research Communications ·Guillaume Guerlet, Antoine Taly, Lia Prado de Carvalho, Adeline Martz, Ruotian Jiang, Alexandre Specht, Nicolas Le Novère, Thomas Grütter	2008	8
17	Minimum information requested in the annotation of biochemical models (MIRIAM) Nature Biotechnology ·Nicolas Le Novère, Andrew Finney, Michael Hucka, Upinder S. Bhalla, Fabien Campagne, Julio Collado‐Vides, Edmund J. Crampin, Matt Halstead, Edda Klipp, Pedro Mendes, Poul MF Nielsen, Herbert M. Sauro, Bruce E. Shapiro, Jacky L. Snoep, H. D. Spence, Barry L. Wanner	2005	390
18	Normal Mode Analysis Suggests a Quaternary Twist Model for the Nicotinic Receptor Gating Mechanism Biophysical Journal ·Antoine Taly, Marc Delarue, Thomas Grütter, Michaël Nilges, Nicolas Le Novère, Pierre‐Jean Corringer, Jean‐Pierre Changeux	2005	161
19	Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis Nature Cell Biology ·Thomas Shimizu, Nicolas Le Novère, Matthew D. Levin, Andrew J. Beavil, Brian J. Sutton, Dennis Bray	2000	158
20	Promoter elements conferring neuron-specific expression of the β2-subunit of the neuronal nicotinic acetylcholine receptor studiedin vitro and in transgenic mice Neuroscience ·Alain Bessis, A.-M. Salmon, Michèle Zoli, Nicolas Le Novère, Marina R. Picciotto, Jean‐Pierre Changeux	1995	55

About Nicolas Le Novère

Nicolas Le Novère is a scholar working on Information Systems and Management, Molecular Biology, Cellular and Molecular Neuroscience, Aging and Biophysics, having authored 138 papers that have together received 11.0k indexed citations. Recurring topics across this work include Gene Regulatory Network Analysis (50 papers), Bioinformatics and Genomic Networks (46 papers), Microbial Metabolic Engineering and Bioproduction (41 papers), Receptor Mechanisms and Signaling (26 papers), Nicotinic Acetylcholine Receptors Study (25 papers), Biomedical Text Mining and Ontologies (19 papers), Scientific Computing and Data Management (15 papers) and Neuroscience and Neuropharmacology Research (14 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (2.6k citations), Molecular Biology (9.3k citations), Information Systems and Management (429 citations), Pharmacology (925 citations) and Biophysics (304 citations). Nicolas Le Novère has collaborated with scholars based in United Kingdom, United States and France. Frequent co-authors include Jean‐Pierre Changeux, Pierre‐Jean Corringer, Michèle Zoli, Melanie I. Stefan, Camille Laibe, Jean‐Pierre Changeux, Clément Léna, Vijayalakshmi Chelliah, Michael Hucka and Matilde Cordero‐Erausquin. Their work appears in journals such as Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics, BMC Systems Biology, Nucleic Acids Research, Bioinformatics and BMC Bioinformatics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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