Jean‐Pierre Changeux

68.8k total citations · 17 hit papers
501 papers, 52.6k citations indexed

About

Jean‐Pierre Changeux is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Cognitive Neuroscience. According to data from OpenAlex, Jean‐Pierre Changeux has authored 501 papers receiving a total of 52.6k indexed citations (citations by other indexed papers that have themselves been cited), including 352 papers in Molecular Biology, 213 papers in Cellular and Molecular Neuroscience and 46 papers in Cognitive Neuroscience. Recurrent topics in Jean‐Pierre Changeux's work include Nicotinic Acetylcholine Receptors Study (229 papers), Receptor Mechanisms and Signaling (146 papers) and Ion channel regulation and function (143 papers). Jean‐Pierre Changeux is often cited by papers focused on Nicotinic Acetylcholine Receptors Study (229 papers), Receptor Mechanisms and Signaling (146 papers) and Ion channel regulation and function (143 papers). Jean‐Pierre Changeux collaborates with scholars based in France, United States and Italy. Jean‐Pierre Changeux's co-authors include Jacques Monod, Jeffries Wyman, Stanislas Dehaene, Pierre‐Jean Corringer, Nicolas Le Novère, Michèle Zoli, Clément Léna, Stuart J. Edelstein, François Jacob and Anne Devillers‐Thiéry and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Jean‐Pierre Changeux

489 papers receiving 49.5k citations

Hit Papers

On the nature of allosteric transitions: A plausible model 1963 2026 1984 2005 1965 1963 2011 1998 1976 2.0k 4.0k 6.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. On the nature of allosteric transitions: A plausible model
    1965 7.0k citations Jean‐Pierre Changeux et al. profile →
  2. Allosteric proteins and cellular control systems
    1963 1.6k citations Jean‐Pierre Changeux et al. profile →
  3. Experimental and Theoretical Approaches to Conscious Processing
    2011 1.5k citations Stanislas Dehaene, Jean‐Pierre Changeux profile →
  4. Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine
    1998 1.1k citations Lisa M. Marubio, Jean‐Pierre Changeux et al. profile →
  5. Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks
    1976 978 citations Jean‐Pierre Changeux et al. profile →
  6. A neuronal model of a global workspace in effortful cognitive tasks
    1998 839 citations Stanislas Dehaene, Jean‐Pierre Changeux et al. Proceedings of the National Academy of Sciences profile →
  7. Nicotinic Receptors at the Amino Acid Level
    2000 673 citations Pierre‐Jean Corringer, Jean‐Pierre Changeux et al. profile →
  8. Allosteric Mechanisms of Signal Transduction
    2005 595 citations Jean‐Pierre Changeux, Stuart J. Edelstein profile →
  9. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
    2008 578 citations Hugues Nury, Marc Baaden et al. profile →
  10. Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei.
    2001 558 citations Jean‐Pierre Changeux et al. profile →
  11. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain
    1995 554 citations Jean‐Pierre Changeux et al. profile →
  12. Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
    2009 549 citations Pierre‐Jean Corringer, Jean‐Pierre Changeux et al. profile →
  13. Molecular and Physiological Diversity of Nicotinic Acetylcholine Receptors in the Midbrain Dopaminergic Nuclei
    2001 529 citations Jean‐Pierre Changeux et al. Journal of Neuroscience profile →
  14. Development of Elementary Numerical Abilities: A Neuronal Model
    1993 526 citations Stanislas Dehaene, Jean‐Pierre Changeux profile →
  15. A neuronal network model linking subjective reports and objective physiological data during conscious perception
    2003 524 citations Stanislas Dehaene, Jean‐Pierre Changeux et al. Proceedings of the National Academy of Sciences profile →
  16. Use of a Snake Venom Toxin to Characterize the Cholinergic Receptor Protein
    1970 449 citations Jean‐Pierre Changeux et al. Proceedings of the National Academy of Sciences profile →
  17. A Neuronal Model of Predictive Coding Accounting for the Mismatch Negativity
    2012 380 citations Jean‐Pierre Changeux, Stanislas Dehaene et al. Journal of Neuroscience profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jean‐Pierre Changeux France 113 37.1k 17.4k 6.8k 5.8k 3.8k 501 52.6k
William A. Catterall United States 141 54.4k 1.5× 37.3k 2.1× 3.2k 0.5× 4.3k 0.7× 2.7k 0.7× 484 70.1k
Marc G. Caron United States 158 54.9k 1.5× 45.8k 2.6× 4.7k 0.7× 5.2k 0.9× 3.2k 0.8× 596 80.1k
Michael J. Berridge United Kingdom 96 42.2k 1.1× 19.2k 1.1× 1.1k 0.2× 9.8k 1.7× 1.9k 0.5× 210 65.7k
Eric R. Kandel United States 156 31.6k 0.9× 47.2k 2.7× 24.0k 3.5× 5.8k 1.0× 3.3k 0.9× 495 77.6k
Roger Y. Tsien United States 151 70.9k 1.9× 28.4k 1.6× 2.8k 0.4× 11.9k 2.1× 1.9k 0.5× 321 111.4k
Peter H. Seeburg Germany 112 34.1k 0.9× 26.1k 1.5× 5.7k 0.8× 2.1k 0.4× 931 0.2× 229 56.1k
Erwin Neher Germany 110 42.8k 1.2× 33.9k 1.9× 5.3k 0.8× 11.3k 2.0× 697 0.2× 256 57.0k
David E. Clapham United States 117 33.0k 0.9× 17.0k 1.0× 1.2k 0.2× 4.0k 0.7× 1.5k 0.4× 326 57.4k
Solomon H. Snyder United States 200 74.9k 2.0× 59.1k 3.4× 5.8k 0.9× 10.3k 1.8× 6.8k 1.8× 1.0k 143.6k
David J. Anderson United States 123 25.1k 0.7× 18.6k 1.1× 5.7k 0.8× 4.3k 0.7× 1.3k 0.3× 419 50.3k

Countries citing papers authored by Jean‐Pierre Changeux

Since Specialization
Citations

This map shows the geographic impact of Jean‐Pierre Changeux's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean‐Pierre Changeux with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean‐Pierre Changeux more than expected).

Fields of papers citing papers by Jean‐Pierre Changeux

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean‐Pierre Changeux. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean‐Pierre Changeux. The network helps show where Jean‐Pierre Changeux may publish in the future.

Co-authorship network of co-authors of Jean‐Pierre Changeux

This figure shows the co-authorship network connecting the top 25 collaborators of Jean‐Pierre Changeux. A scholar is included among the top collaborators of Jean‐Pierre Changeux based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jean‐Pierre Changeux. Jean‐Pierre Changeux is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Hibbs, Ryan, et al.. (2025). Hidden complexity of α7 nicotinic acetylcholine receptor desensitization revealed by MD simulations and Markov state modeling. Proceedings of the National Academy of Sciences. 122(7). e2420993122–e2420993122. 2 indexed citations
2.
Lefebvre, S., et al.. (2023). Illumination of a progressive allosteric mechanism mediating the glycine receptor activation. Nature Communications. 14(1). 795–795. 9 indexed citations
3.
Changeux, Jean‐Pierre, et al.. (2022). Lateral fenestrations in the extracellular domain of the glycine receptor contribute to the main chloride permeation pathway. Science Advances. 8(41). eadc9340–eadc9340. 4 indexed citations
4.
Goulas, Alexandros, Jean‐Pierre Changeux, Konrad Wagstyl, et al.. (2021). The natural axis of transmitter receptor distribution in the human cerebral cortex. Proceedings of the National Academy of Sciences. 118(3). 59 indexed citations
5.
Prevost, Marie S., Gustavo Moraga‐Cid, Catherine Van Renterghem, et al.. (2013). Intermediate closed state for glycine receptor function revealed by cysteine cross-linking. Proceedings of the National Academy of Sciences. 110(42). 17113–17118. 16 indexed citations
6.
Sauguet, Ludovic, Azadeh Shahsavar, Frédéric Poitevin, et al.. (2013). Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proceedings of the National Academy of Sciences. 111(3). 966–971. 155 indexed citations
7.
Nury, Hugues, Frédéric Poitevin, Catherine Van Renterghem, et al.. (2010). One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proceedings of the National Academy of Sciences. 107(14). 6275–6280. 133 indexed citations
8.
Strochlic, Laure, Annie Cartaud, Alexandre Méjat, et al.. (2004). 14-3-3 γ associates with muscle specific kinase and regulates synaptic gene transcription at vertebrate neuromuscular synapse. Proceedings of the National Academy of Sciences. 101(52). 18189–18194. 34 indexed citations
9.
Mechawar, Naguib, Armen Saghatelyan, Régis Grailhe, et al.. (2004). Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proceedings of the National Academy of Sciences. 101(26). 9822–9826. 87 indexed citations
10.
Paas, Yoav, Jean Cartaud, Michel Recouvreur, et al.. (2003). Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid–detergent matrices. Proceedings of the National Academy of Sciences. 100(20). 11309–11314. 28 indexed citations
11.
Dehaene, Stanislas & Jean‐Pierre Changeux. (2000). Reward-dependent learning in neuronal networks for planning and decision making. Progress in brain research. 126. 217–229. 88 indexed citations
12.
Jiménez, María del Mar Arroyo, Jean‐Pierre Bourgeois, Lisa M. Marubio, et al.. (1999). Ultrastructural Localization of the α4-Subunit of the Neuronal Acetylcholine Nicotinic Receptor in the Rat Substantia Nigra. Journal of Neuroscience. 19(15). 6475–6487. 98 indexed citations
13.
Changeux, Jean‐Pierre & Paul Ricœur. (1998). Ce Qui Nous Fait Penser la Nature Et la Règle. 31 indexed citations
14.
Devillers‐Thiéry, Anne, Jean‐Luc Galzi, S. Bertrand, Jean‐Pierre Changeux, & Daniel Bertrand. (1992). Stratified organization of the nicotinic acetylcholine receptor channel. Neuroreport. 3(11). 1001–1004. 52 indexed citations
15.
Piette, Jacques, Monique Huchet, Aymeric Duclert, Atsuko Fujisawa‐Sehara, & Jean‐Pierre Changeux. (1992). Localization of mRNAs coding for CMD1, myogenin and the α-subunit of the acetylcholine receptor during skeletal muscle development in the chicken. Mechanisms of Development. 37(1-2). 95–106. 33 indexed citations
16.
Galzi, Jean‐Luc, Daniel Bertrand, Anne Devillers‐Thiéry, et al.. (1991). Functional significance of aromatic amino acids from three peptide loops of the α7 neuronal nicotinic receptor site investigated by site‐directed mutagenesis. FEBS Letters. 294(3). 198–202. 144 indexed citations
17.
Changeux, Jean‐Pierre & Stanislas Dehaene. (1990). Neuronal models of cognitive functions. MIT Press eBooks. 63–109. 6 indexed citations
18.
Changeux, Jean‐Pierre & Alain Connes. (1989). MATIERE A PENSEE. 20 indexed citations
19.
Changeux, Jean‐Pierre & David Nachmansohn. (1985). Molecular basis of nerve activity : proceedings of the International Symposium in Memory of David Nachmansohn (1899-1983), Berlin (West) Germany, October 11-13, 1984. De Gruyter eBooks. 1 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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