Bruce R. Conklin

25.2k total citations · 6 hit papers
151 papers, 15.3k citations indexed

About

Bruce R. Conklin is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Biomedical Engineering. According to data from OpenAlex, Bruce R. Conklin has authored 151 papers receiving a total of 15.3k indexed citations (citations by other indexed papers that have themselves been cited), including 117 papers in Molecular Biology, 35 papers in Cellular and Molecular Neuroscience and 27 papers in Biomedical Engineering. Recurrent topics in Bruce R. Conklin's work include CRISPR and Genetic Engineering (33 papers), Receptor Mechanisms and Signaling (30 papers) and Pluripotent Stem Cells Research (29 papers). Bruce R. Conklin is often cited by papers focused on CRISPR and Genetic Engineering (33 papers), Receptor Mechanisms and Signaling (30 papers) and Pluripotent Stem Cells Research (29 papers). Bruce R. Conklin collaborates with scholars based in United States, Japan and Netherlands. Bruce R. Conklin's co-authors include Henry R. Bourne, Nathan Salomonis, Alexander R. Pico, Kristina Hanspers, Karen Vranizan, Chris T. Evelo, Thomas Kelder, Martijn van Iersel, Mohammad A. Mandegar and Edward C. Hsiao and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Bruce R. Conklin

148 papers receiving 15.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data

2003 703 citations Nathan Salomonis, Karen Vranizan et al. Genome biology profile →
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα

1993 626 citations Bruce R. Conklin et al. profile →
Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits

1992 537 citations Bruce R. Conklin et al. profile →
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells

2016 530 citations Siyuan Liu, Max A. Horlbeck et al. Science profile →
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

2016 480 citations Michael J. Workman, Maxime M. Mahé et al. Nature Medicine profile →
Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

2015 386 citations Anurag Mathur, Peter Loskill et al. profile →

Peers

Countries citing papers authored by Bruce R. Conklin

Since Specialization

Citations

This map shows the geographic impact of Bruce R. Conklin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce R. Conklin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce R. Conklin more than expected).

Fields of papers citing papers by Bruce R. Conklin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce R. Conklin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce R. Conklin. The network helps show where Bruce R. Conklin may publish in the future.

Co-authorship network of co-authors of Bruce R. Conklin

This figure shows the co-authorship network connecting the top 25 collaborators of Bruce R. Conklin. A scholar is included among the top collaborators of Bruce R. Conklin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bruce R. Conklin. Bruce R. Conklin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A microphysiological system for screening lipid nanoparticle−mRNA complexes predicts in vivo heart transfection efficacy 2025 ·Nature Biomedical Engineering ·(unknown), Mauro W. Costa, Hesong Han, (unknown), Tammy Ng, Brian Siemons, Tomohiro Nishino, Yu Huang, (unknown), Kenneth Wu, Luke M. Judge, Bruce R. Conklin, Deepak Srivastava, Niren Murthy, Kevin E. Healy	0
2	Generation and characterization of an isogenic control line by correcting the BAG3 P209L mutation of a human induced pluripotent stem cell (hiPSC) line from a patient with myofibrillar myopathy-6 2024 ·Stem Cell Research ·(unknown), (unknown), Luke M. Judge, Bruce R. Conklin, Bernd K. Fleischmann, Michael Hesse	0
3	Permittivity tensor imaging: modular label-free imaging of 3D dry mass and 3D orientation at high resolution 2024 ·Nature Methods ·Li-Hao Yeh, Ivan E. Ivanov, (unknown), (unknown), Bryant B. Chhun, (unknown), C. B. Foltz, Ezzat Hashemi, Juan A. Pérez-Bermejo, Huijun Wang, Yan‐Hao Yu, Peter G. Kazansky, Bruce R. Conklin, May Han, Shalin B. Mehta	9
4	Advances and challenges in modeling inherited peripheral neuropathies using iPSCs 2024 ·Experimental & Molecular Medicine ·Jonas Van Lent, (unknown), (unknown), (unknown), Marina Kennerson, Tim Vangansewinkel, Esther Wolfs, (unknown), Zachary S. Nevin, Luke M. Judge, Bruce R. Conklin, Henna Tyynismaa, Alex Clark, David Bennett, Ludo Van Den Bosch, Mario Saporta, Vincent Timmerman	10
5	Reversal of C9orf72 mutation-induced transcriptional dysregulation and pathology in cultured human neurons by allele-specific excision 2024 ·Proceedings of the National Academy of Sciences ·(unknown), (unknown), (unknown), (unknown), (unknown), Katherine A. Brown, (unknown), (unknown), (unknown), Hannah L. Watry, (unknown), Kathleen C. Keough, Yu‐Chih Tsai, Alec S.T. Smith, Bruce R. Conklin, Claire D. Clelland	5
6	Functional analysis of a common BAG3 allele associated with protection from heart failure 2023 ·Nature Cardiovascular Research ·Juan A. Pérez-Bermejo, Luke M. Judge, (unknown), Kenneth Wu, Hannah L. Watry, Annie Truong, Jaclyn J. Ho, Matthew Carter, (unknown), Robyn M. Kaake, Ernst H. Pulido, Mohammad A. Mandegar, Danielle L. Swaney, Po-Lin So, Nevan J. Krogan, Bruce R. Conklin	3
7	SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19 2021 ·Science Translational Medicine ·Juan A. Pérez-Bermejo, Michael S. Kang, Sarah J. Rockwood, Camille R. Simoneau, David Joy, (unknown), Gokul N. Ramadoss, Will Flanigan, Parinaz Fozouni, Huihui Li, Peiyi Chen, Ken Nakamura, Jeffrey D. Whitman, Paul Hanson, Bruce M. McManus, Mélanie Ott, Bruce R. Conklin, Todd C. McDevitt	130
8	Maladaptive Contractility of 3D Human Cardiac Microtissues to Mechanical Nonuniformity 2020 ·Advanced Healthcare Materials ·Chenyan Wang, Sang‐Mo Koo, (unknown), Zacharias Vangelatos, (unknown), Bruce R. Conklin, Costas P. Grigoropoulos, Kevin E. Healy, Zhen Ma	15
9	Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq 2019 ·Science ·Beeke Wienert, Stacia K. Wyman, Chris D. Richardson, Charles D. Yeh, Pınar Akçakaya, Michelle J. Porritt, (unknown), Jonathan T. Vu, Katelynn R. Kazane, Hannah L. Watry, Luke M. Judge, Bruce R. Conklin, Marcello Maresca, Jacob E. Corn	284
10	AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design 2019 ·Genome biology ·Kathleen C. Keough, Svetlana Lyalina, Michael Olvera, Sean Whalen, Bruce R. Conklin, Katherine S. Pollard	19
11	CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells breakdown → 2016 ·Science ·Siyuan Liu, Max A. Horlbeck, Seung Woo Cho, Harjus Birk, Martina Malatesta, Daniel He, Frank J. Attenello, Jacqueline E. Villalta, Min Y. Cho, Yuwen Chen, Mohammad A. Mandegar, Michael Olvera, Luke A. Gilbert, Bruce R. Conklin, Howard Y. Chang, Jonathan S. Weissman, Daniel A. Lim	530
12	Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system breakdown → 2016 ·Nature Medicine ·Michael J. Workman, Maxime M. Mahé, Stephen L. Trisno, Holly M. Poling, Carey L. Watson, Nambirajan Sundaram, Ching‐Fang Chang, Jacqueline V. Schiesser, P. Aubert, Edouard G. Stanley, Andrew G. Elefanty, Yuichiro Miyaoka, Mohammad A. Mandegar, Bruce R. Conklin, Michel Neunlist, Samantha A. Brugmann, Michael A. Helmrath, James M. Wells	480
13	Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome 2015 ·Acta Neuropathologica ·Hiroko Nobuta, Maria Roberta Cilio, Olivier Danhaive, Hui‐Hsin Tsai, Srinivasan Tupal, Sandra Chang, Alice T. Murnen, (unknown), (unknown), Catherine Czeisler, Hamza N. Gokozan, (unknown), (unknown), Debra E. Weese‐Mayer, Bruce R. Conklin, Siu‐Pok Yee, Eric J. Huang, Paul A. Gray, David H. Rowitch, José Javier Otero	37
14	Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales 2014 ·Tissue Engineering Part C Methods ·Nathaniel Huebsch, Peter Loskill, Mohammad A. Mandegar, (unknown), (unknown), Zhen Ma, Anurag Mathur, (unknown), (unknown), Luke M. Judge, C. Ian Spencer, (unknown), (unknown), (unknown), Bruce R. Conklin, Kevin E. Healy	226
15	Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation 2013 ·Orphanet Journal of Rare Diseases ·Yoshihisa Matsumoto, Yohei Hayashi, Christopher R. Schlieve, Makoto Ikeya, Hannah Kim, Trieu Nguyen, Salma Sami, Shiro Baba, Emilie Barruet, (unknown), Isao Asaka, Takanobu Otsuka, Shinya Yamanaka, Bruce R. Conklin, Junya Toguchida, Edward C. Hsiao	89
16	Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation 2010 ·Proceedings of the National Academy of Sciences ·Nathan Salomonis, Christopher R. Schlieve, Laura Pereira, Christine Wahlquist, Alexandre R. Colas, Alexander C. Zambon, Karen Vranizan, Matthew Spindler, Alexander R. Pico, Melissa Cline, Tyson A. Clark, Alan J. Williams, John E. Blume, Eva Samal, Mark Mercola, Bradley J. Merrill, Bruce R. Conklin	175
17	Osteoblast expression of an engineered G _s -coupled receptor dramatically increases bone mass 2008 ·Proceedings of the National Academy of Sciences ·Edward C. Hsiao, Benjamin Boudignon, Wei Chun Chang, (unknown), Jeffrey Peng, Trieu Nguyen, (unknown), Bernard P. Halloran, Bruce R. Conklin, Robert A. Nissenson	87
18	MicroRNA Regulation of Cell Lineages in Mouse and Human Embryonic Stem Cells 2008 ·Cell stem cell ·Kathryn N. Ivey, (unknown), (unknown), Frank W. King, Ru-Fang Yeh, Jason E. Fish, Edward C. Hsiao, Robert J. Schwartz, Bruce R. Conklin, Harold S. Bernstein, Deepak Srivastava	478
19	Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans 2004 ·Journal of Clinical Investigation ·(unknown), Cécile Lubrano-Berthelier, Cédric Govaerts, Franck Picard, Pamela Santiago, Bruce R. Conklin, (unknown)	173
20	Tetracycline-inducible system for photoreceptor-specific gene expression. 2000 ·PubMed ·Michelle Chang, James W. Horner, Bruce R. Conklin, Ronald A. DePinho, Dean Bok, Donald J. Zack	33

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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