Michael Wigler

67.1k total citations · 24 hit papers
222 papers, 47.0k citations indexed

About

Michael Wigler is a scholar working on Molecular Biology, Genetics and Cell Biology. According to data from OpenAlex, Michael Wigler has authored 222 papers receiving a total of 47.0k indexed citations (citations by other indexed papers that have themselves been cited), including 186 papers in Molecular Biology, 61 papers in Genetics and 27 papers in Cell Biology. Recurrent topics in Michael Wigler's work include Fungal and yeast genetics research (60 papers), Genomic variations and chromosomal abnormalities (37 papers) and Protein Kinase Regulation and GTPase Signaling (37 papers). Michael Wigler is often cited by papers focused on Fungal and yeast genetics research (60 papers), Genomic variations and chromosomal abnormalities (37 papers) and Protein Kinase Regulation and GTPase Signaling (37 papers). Michael Wigler collaborates with scholars based in United States, Germany and Sweden. Michael Wigler's co-authors include Richard Axel, Saul J. Silverstein, Àngel Pellicer, Linda Rodgers, Daniel Broek, Mitchell Goldfarb, Scott Powers, Ottavio Fasano, Scott J. Cameron and Manuel Perucho and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Michael Wigler

219 papers receiving 44.7k citations

Hit Papers

PTEN , a Putative Protein Tyrosine Phosphatase Gene... 1977 2026 1993 2009 1997 2011 2004 2004 1979 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
    1997 3.9k citations Linda Rodgers, Michael Wigler et al. profile →
  2. Tumour evolution inferred by single-cell sequencing
    2011 1.8k citations Linda Rodgers, Diane Esposito et al. profile →
  3. Large-Scale Copy Number Polymorphism in the Human Genome
    2004 1.8k citations Jonathan Sebat, John Healy et al. profile →
  4. Circular binary segmentation for the analysis of array-based DNA copy number data
    2004 1.5k citations Michael Wigler et al. profile →
  5. Transformation of mammalian cells with genes from procaryotes and eucaryotes
    1979 1.3k citations Michael Wigler et al. profile →
  6. DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.
    1979 1.3k citations Michael Wigler et al. Proceedings of the National Academy of Sciences profile →
  7. Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells
    1977 1.2k citations Michael Wigler et al. profile →
  8. Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor
    1978 1.2k citations Michael Wigler et al. profile →
  9. Cloning the Differences Between Two Complex Genomes
    1993 1.0k citations Н. А. Лисицын, Michael Wigler et al. profile →
  10. In yeast, RAS proteins are controlling elements of adenylate cyclase
    1985 993 citations Scott Powers, Daniel Broek et al. profile →
  11. The lipid phosphatase activity of PTEN is critical for its tumor supressor function
    1998 977 citations Michael Wigler et al. Proceedings of the National Academy of Sciences profile →
  12. Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.
    1988 883 citations Jeffrey Field, Jun‐ichi Nikawa et al. Molecular and Cellular Biology profile →
  13. Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach
    2006 861 citations Michael Wigler, Scott Powers et al. profile →
  14. Human Sos1: a Guanine Nucleotide Exchange Factor for Ras that Binds to GRB2
    1993 697 citations Jacques Camonis, Michael Wigler et al. profile →
  15. The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins
    1990 681 citations Roymarie Ballester, Douglas A. Marchuk et al. profile →
  16. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
    1997 657 citations Michael Wigler et al. Proceedings of the National Academy of Sciences profile →
  17. Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase
    1987 613 citations Michael Wigler et al. profile →
  18. Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene
    2008 603 citations Jonathan Sebat, Michael Wigler et al. profile →
  19. Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change
    1982 596 citations Michael Wigler et al. profile →
  20. Multiple ras functions can contribute to mammalian cell transformation
    1995 596 citations Michael A. White, Michael Wigler et al. profile →
  21. Complex formation between RAS and RAF and other protein kinases.
    1993 552 citations Maureen M. Barr, S Marcus et al. Proceedings of the National Academy of Sciences profile →
  22. Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders
    2011 484 citations Anthony Leotta, Kenny Ye et al. profile →
  23. Structure and activation of the human N-ras gene
    1983 460 citations Michael Wigler et al. profile →
  24. Genetic and physical linkage of exogenous sequences in transformed cells
    1980 418 citations Manuel Perucho, Douglas Hanahan et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Michael Wigler United States 103 35.3k 10.6k 7.2k 6.2k 5.7k 222 47.0k
David W. Russell United States 126 29.5k 0.8× 11.2k 1.1× 8.0k 1.1× 4.7k 0.8× 3.8k 0.7× 542 52.6k
J. Michael Bishop United States 116 33.0k 0.9× 11.4k 1.1× 9.5k 1.3× 5.1k 0.8× 4.5k 0.8× 356 48.6k
Jan H.J. Hoeijmakers Netherlands 107 38.1k 1.1× 5.8k 0.5× 7.8k 1.1× 8.4k 1.3× 2.8k 0.5× 399 48.0k
Andrew P. Feinberg United States 92 45.0k 1.3× 15.5k 1.5× 5.9k 0.8× 6.8k 1.1× 2.4k 0.4× 235 62.2k
Joe W. Gray United States 99 26.8k 0.8× 12.1k 1.1× 11.5k 1.6× 10.8k 1.7× 3.9k 0.7× 487 46.4k
David M. Livingston United States 102 30.8k 0.9× 10.6k 1.0× 16.1k 2.2× 7.6k 1.2× 3.0k 0.5× 251 41.4k
David E. Housman United States 104 32.2k 0.9× 9.2k 0.9× 9.8k 1.4× 3.8k 0.6× 2.7k 0.5× 329 47.8k
Hediye Erdjument‐Bromage United States 125 53.4k 1.5× 5.5k 0.5× 7.4k 1.0× 6.0k 1.0× 7.7k 1.3× 285 68.1k
Richard A. Young United States 134 59.3k 1.7× 7.6k 0.7× 6.1k 0.9× 7.2k 1.2× 3.2k 0.6× 287 70.5k
Jerry W. Shay United States 118 35.3k 1.0× 5.2k 0.5× 8.9k 1.2× 4.9k 0.8× 2.2k 0.4× 522 58.0k

Countries citing papers authored by Michael Wigler

Since Specialization
Citations

This map shows the geographic impact of Michael Wigler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Wigler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Wigler more than expected).

Fields of papers citing papers by Michael Wigler

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Wigler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Wigler. The network helps show where Michael Wigler may publish in the future.

Co-authorship network of co-authors of Michael Wigler

This figure shows the co-authorship network connecting the top 25 collaborators of Michael Wigler. A scholar is included among the top collaborators of Michael Wigler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael Wigler. Michael Wigler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Buja, Andreas, Natalia Volfovsky, Abba Μ. Krieger, et al.. (2018). Damaging de novo mutations diminish motor skills in children on the autism spectrum. Proceedings of the National Academy of Sciences. 115(8). E1859–E1866. 44 indexed citations
2.
Zhao, Xiaoyue, Anthony Leotta, Vlad Kustanovich, et al.. (2007). A unified genetic theory for sporadic and inherited autism. Proceedings of the National Academy of Sciences. 104(31). 12831–12836. 223 indexed citations
3.
Healy, John, et al.. (2003). Annotating Large Genomes With Exact Word Matches. Genome Research. 13(10). 2306–2315. 53 indexed citations
4.
Hamaguchi, Masaaki, Jennifer Meth, Christine von Klitzing, et al.. (2002). DBC2 , a candidate for a tumor suppressor gene involved in breast cancer. Proceedings of the National Academy of Sciences. 99(21). 13647–13652. 177 indexed citations
5.
Tu, Hua & Michael Wigler. (1999). Genetic Evidence for Pak1 Autoinhibition and Its Release by Cdc42. Molecular and Cellular Biology. 19(1). 602–611. 81 indexed citations
6.
Tu, Hua, et al.. (1997). Multiple Regulatory Domains on the Byr2 Protein Kinase. Molecular and Cellular Biology. 17(10). 5876–5887. 71 indexed citations
7.
Thiagalingam, Sam, Н. А. Лисицын, Masaaki Hamaguchi, et al.. (1996). Evaluation of the FHIT gene in colorectal cancers.. PubMed. 56(13). 2936–9. 106 indexed citations
8.
Jung, Vincent, et al.. (1995). Mutations in the SHR5 Gene of Saccharomyces cerevisiae Suppress Ras Function and Block Membrane Attachment and Palmitoylation of Ras Proteins. Molecular and Cellular Biology. 15(3). 1333–1342. 23 indexed citations
9.
Лисицын, Н. А. & Michael Wigler. (1995). [19] Representational difference analysis in detection of genetic lesions in cancer. Methods in enzymology on CD-ROM/Methods in enzymology. 254. 291–304. 53 indexed citations
10.
Xu, Haopeng, Michael A. White, Stevan Marcus, & Michael Wigler. (1994). Concerted action of RAS and G proteins in the sexual response pathways of Schizosaccharomyces pombe. Molecular and Cellular Biology. 14(1). 50–58. 30 indexed citations
11.
Andersen, Lone B., Roymarie Ballester, Douglas A. Marchuk, et al.. (1993). A Conserved Alternative Splice in the von Recklinghausen Neurofibromatosis ( NF1 ) Gene Produces Two Neurofibromin Isoforms, Both of Which Have GTPase-Activating Protein Activity. Molecular and Cellular Biology. 13(1). 487–495. 137 indexed citations
12.
Neiman, Aaron M., Brian J. Stevenson, G. F. Sprague, et al.. (1993). Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms.. Molecular Biology of the Cell. 4(1). 107–120. 142 indexed citations
13.
Bolger, Graeme B., Tamar Michaeli, Tom St. John, et al.. (1993). A Family of Human Phosphodiesterases Homologous to the Dunce Learning and Memory Gene Product of Drosophila melanogaster are Potential Targets for Antidepressant Drugs. Molecular and Cellular Biology. 13(10). 6558–6571. 256 indexed citations
14.
Xu, Hengyi, T B Rajavashisth, Vincent Jung, et al.. (1992). A gene encoding a protein with seven zinc finger domains acts on the sexual differentiation pathways of Schizosaccharomyces pombe.. Molecular Biology of the Cell. 3(7). 721–734. 42 indexed citations
15.
Kawamukai, Makoto, K M Ferguson, Michael Wigler, & Dallan Young. (1991). Genetic and biochemical analysis of the adenylyl cyclase of Schizosaccharomyces pombe.. PubMed. 2(2). 155–164. 81 indexed citations
16.
Watson, James Dewey, Michael Wigler, & James R. Feramisco. (1988). Abstracts of papers presented at the LIII Cold Spring Harbor Symposium on Quantitative Biology : the Molecular Biology of Signal Transduction, May 25-June 1, 1988. 1 indexed citations
17.
Field, Jeffrey, Jun‐ichi Nikawa, Daniel Broek, et al.. (1988). Purification of a RAS -Responsive Adenylyl Cyclase Complex from Saccharomyces cerevisiae by Use of an Epitope Addition Method. Molecular and Cellular Biology. 8(5). 2159–2165. 327 indexed citations
18.
Kishimoto, Takeo, et al.. (1986). INDUCTION OF OOCYTE MATURATION BY INJECTION OF ONCOGENIC H-ras PROTEIN IN THE STARFISH : Developmental Biology. ZOOLOGICAL SCIENCE. 3(6). 1036. 1 indexed citations
19.
Perucho, Manuel & Michael Wigler. (1981). Linkage and Expression of Foreign DNA in Cultured Animal Cells. Cold Spring Harbor Symposia on Quantitative Biology. 45(0). 829–838. 26 indexed citations
20.
Wigler, Michael, Manuel Perucho, Leah Lipsich, et al.. (1980). DNA Mediated Gene Transfer: Theory and Application. Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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