Michael S.Y. Huen

6.0k citations

84 papers · 4.6k indexed · 1 hit paper · h-index 34

Co-authors: Junjie Chen Shirley M.-H. Sy Xiaochun Yu Kay Minn Michael B. Yaffe Robert A. Grant Isaac A. Manke Jun Huang
Topics: DNA Repair Mechanisms (55 papers)Genomics and Chromatin Dynamics (19 papers)Ubiquitin and proteasome pathways (18 papers)
Cited by: Molecular Biology Oncology Cancer Research
Journals: Cell Proceedings of the National Academy of Sciences Nucleic Acids Research
Partner nations: Hong Kong China United States

In The Last Decade

Michael S.Y. Huen

83 papers receiving 4.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly

2007 821 citations Michael S.Y. Huen, Junjie Chen et al. profile →

Peers

Countries citing papers authored by Michael S.Y. Huen

Since Specialization

Citations

This map shows the geographic impact of Michael S.Y. Huen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael S.Y. Huen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael S.Y. Huen more than expected).

Fields of papers citing papers by Michael S.Y. Huen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael S.Y. Huen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael S.Y. Huen. The network helps show where Michael S.Y. Huen may publish in the future.

Co-authorship network of co-authors of Michael S.Y. Huen

This figure shows the co-authorship network connecting the top 25 collaborators of Michael S.Y. Huen. A scholar is included among the top collaborators of Michael S.Y. Huen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael S.Y. Huen. Michael S.Y. Huen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The PARP1–EXD2 axis orchestrates R-loop resolution to safeguard genome stability 2025 ·Nature Chemical Biology ·Zhaoshuang Li,(unknown),(unknown),(unknown),Michael S.Y. Huen,Huasong Lu,Zhigang Zhang,Jianwei Zhou,Fang Dong,Ting Liu,Jun Huang	1
2	Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma 2024 ·Clinical Cancer Research ·Horace H.Y. Lee,(unknown),(unknown),(unknown),Alice S.T. Wong,Grace H.W. Cheng,(unknown),Hoi Cheong Siu,(unknown),Michael S.Y. Huen,Ka Yu Tse,Mark R. Bray,Tak W. Mak,Suet Yi Leung,Philip P.C. Ip	2
3	Nuclear F-actin assembly on damaged chromatin is regulated by DYRK1A and Spir1 phosphorylation 2024 ·Nucleic Acids Research ·(unknown),(unknown),(unknown),(unknown),Ching C. Lau,Jun Huang,Jian Yuan,Cheng‐han Yu,Justin Leung,Michael S.Y. Huen	1
4	53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice 2020 ·Cell Death and Differentiation ·(unknown),Peng Li,(unknown),Long Bai,Michael S.Y. Huen,Yidan Liu,Lin‐Yu Lu	28
5	Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin 2020 ·Proceedings of the National Academy of Sciences ·Chao Dong,(unknown),(unknown),(unknown),Toyotaka Ishibashi,Cheng‐han Yu,Shirley M.-H. Sy,Justin Leung,Michael S.Y. Huen	24
6	LC8/DYNLL1 is a 53BP1 effector and regulates checkpoint activation 2019 ·Nucleic Acids Research ·(unknown),(unknown),(unknown),Liwei An,Megan R. Reed,Robert L. Eoff,Jiadong Wang,Michael S.Y. Huen,Justin Leung	35
7	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response 2019 ·Scientific Reports ·(unknown),Chiara Di Vona,Jie Chen,Eva Borràs,Chao Dong,(unknown),Eduard Sabidó,Michael S.Y. Huen,Susana de la Luna	29
8	PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation 2018 ·Cell Reports ·Lok-Hei Chan,Lei Zhou,(unknown),Tin Lok Wong,Terence K. Lee,Rakesh Sharma,Jane Ho Chun Loong,Ching C. Lau,Yunfei Yuan,Dan Xie,Chung Mau Lo,Kwan Man,Benedetta Artegiani,Hans Clevers,Helen H.N. Yan,Suet Yi Leung,Stéphane Richard,Xin‐Yuan Guan,Michael S.Y. Huen,Stephanie Ma	87
9	Dual-utility NLS drives RNF169-dependent DNA damage responses 2017 ·Proceedings of the National Academy of Sciences ·Liwei An,Yiyang Jiang,(unknown),Ellen P.S. Man,Jie Chen,US Khoo,Qingguo Gong,Michael S.Y. Huen	53
10	A Genome-Wide Association Study Identifies Genetic Variants Associated with Mathematics Ability 2017 ·Scientific Reports ·Huan Chen,(unknown),Yuxi Zhou,Zeng Ge,Bin Wang,Wai Ting Siok,Guoqing Wang,Michael S.Y. Huen,Yuyang Jiang,Li‐Hai Tan,Yimin Sun	26
11	AUNIP/C1orf135 directs DNA double-strand breaks towards the homologous recombination repair pathway 2017 ·Nature Communications ·Jiangman Lou,Hongxia Chen,Jinhua Han,Hanqing He,Michael S.Y. Huen,Xin‐Hua Feng,Ting Liu,Jun Huang	30
12	BRCA2 antagonizes classical and alternative nonhomologous end-joining to prevent gross genomic instability 2017 ·Nature Communications ·Jinhua Han,(unknown),Michael S.Y. Huen,Jiadong Wang,Anyong Xie,Chun Fu,Ting Liu,Jun Huang	38
13	TRAIP regulates replication fork recovery and progression via PCNA 2016 ·Cell Discovery ·Wanjuan Feng,Yingying Guo,Jun Huang,Yiqun Deng,Jianye Zang,Michael S.Y. Huen	36
14	Stuttering candidate genes DRD2 but not SLC6A3 is associated with developmental dyslexia in Chinese population 2014 ·Behavioral and Brain Functions ·Huan Chen,Guoqing Wang,(unknown),Yuxi Zhou,Yong Gao,(unknown),Michael S.Y. Huen,Wai Ting Siok,Yuyang Jiang,Li Hai Tan,Yimin Sun	14
15	Impact of G2 checkpoint defect on centromeric instability 2010 ·Oncogene ·(unknown),Sarah Tsao,Grace Wing-Yan Mak,Chi‐Man Tsang,Ching C. Lau,Xin‐Yuan Guan,Michael S.Y. Huen,Annie L.M. Cheung	5
16	SON is a spliceosome-associated factor required for mitotic progression 2010 ·Cell Cycle ·Michael S.Y. Huen,Shirley M.-H. Sy,(unknown),Ching C. Lau,George L. Tipoe,Cornelia Man,Shuo Dong,Junjie Chen	26
17	MRG15 Is a Novel PALB2-interacting Factor Involved in Homologous Recombination 2009 ·Journal of Biological Chemistry ·Shirley M.-H. Sy,Michael S.Y. Huen,Junjie Chen	55
18	BRCA1 and its toolbox for the maintenance of genome integrity 2009 ·Nature Reviews Molecular Cell Biology ·Michael S.Y. Huen,Shirley M.-H. Sy,Junjie Chen	396
19	Active transcription promotes single-stranded oligonucleotide mediated gene repair 2006 ·Biochemical and Biophysical Research Communications ·Michael S.Y. Huen,Lin‐Yu Lu,De‐Pei Liu,Jian‐Dong Huang	14
20	5,7-Dihydroxy-6-methoxyflavone, a benzodiazepine site ligand isolated from Scutellaria baicalensis Georgi, with selective antagonistic properties 2003 ·Biochemical Pharmacology ·Michael S.Y. Huen,Justin Leung,(unknown),(unknown),(unknown),J. Tze‐Fei Wong,Hong Xue	63

About Michael S.Y. Huen

Michael S.Y. Huen is a scholar working on Oncology, Molecular Biology and Cell Biology, having authored 84 papers that have together received 4.6k indexed citations. Recurring topics across this work include DNA Repair Mechanisms (55 papers), Genomics and Chromatin Dynamics (19 papers) and Ubiquitin and proteasome pathways (18 papers). The work is most often cited by research in Molecular Biology (3.9k citations), Oncology (1.5k citations) and Cancer Research (544 citations). Michael S.Y. Huen has collaborated with scholars based in Hong Kong, China and United States. Frequent co-authors include Junjie Chen, Shirley M.-H. Sy, Xiaochun Yu, Kay Minn, Michael B. Yaffe, Robert A. Grant, Isaac A. Manke, Jun Huang, J. N. Mark Glover and Yiqun Deng. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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