Xin‐Yuan Guan

41.8k total citations · 8 hit papers
645 papers, 28.7k citations indexed

About

Xin‐Yuan Guan is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Xin‐Yuan Guan has authored 645 papers receiving a total of 28.7k indexed citations (citations by other indexed papers that have themselves been cited), including 404 papers in Molecular Biology, 158 papers in Cancer Research and 156 papers in Oncology. Recurrent topics in Xin‐Yuan Guan's work include RNA modifications and cancer (86 papers), Cancer-related gene regulation (58 papers) and Genomic variations and chromosomal abnormalities (55 papers). Xin‐Yuan Guan is often cited by papers focused on RNA modifications and cancer (86 papers), Cancer-related gene regulation (58 papers) and Genomic variations and chromosomal abnormalities (55 papers). Xin‐Yuan Guan collaborates with scholars based in China, Hong Kong and United States. Xin‐Yuan Guan's co-authors include Stephanie Ma, Dan Xie, Terence K. Lee, Jeffrey M. Trent, Paul S. Meltzer, Kwok Wah Chan, Li Fu, Liang Hu, Leilei Chen and Irene Oi‐Lin Ng and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Xin‐Yuan Guan

617 papers receiving 28.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer

1997 1.4k citations Xin‐Yuan Guan et al. profile →
Identification and Characterization of Tumorigenic Liver Cancer Stem/Progenitor Cells

2007 967 citations Stephanie Ma, Terence K. Lee et al. profile →
CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway

2007 645 citations Stephanie Ma, Terence K. Lee et al. profile →
N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

2019 537 citations Jiaxing Zhang, Xin‐Yuan Guan et al. profile →
Exploring treatment options in cancer: tumor treatment strategies

2024 412 citations Xin‐Yuan Guan et al. profile →
Cancer stem cells in hepatocellular carcinoma — from origin to clinical implications

2021 327 citations Terence K. Lee, Xin‐Yuan Guan et al. profile →
FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma

2024 54 citations Jiao Huang, Xin‐Yuan Guan et al. Cancer Research profile →
Intrinsic RNA Targeting Triggers Indiscriminate DNase Activity of CRISPR‐Cas12a

2024 48 citations Xin‐Yuan Guan et al. profile →

Peers

Countries citing papers authored by Xin‐Yuan Guan

Since Specialization

Citations

This map shows the geographic impact of Xin‐Yuan Guan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xin‐Yuan Guan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xin‐Yuan Guan more than expected).

Fields of papers citing papers by Xin‐Yuan Guan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xin‐Yuan Guan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xin‐Yuan Guan. The network helps show where Xin‐Yuan Guan may publish in the future.

Co-authorship network of co-authors of Xin‐Yuan Guan

This figure shows the co-authorship network connecting the top 25 collaborators of Xin‐Yuan Guan. A scholar is included among the top collaborators of Xin‐Yuan Guan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xin‐Yuan Guan. Xin‐Yuan Guan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Optimization of operational performance of cantor fractal microchannels under high heat flux conditions 2025 ·International Journal of Thermal Sciences ·Min Xue, (unknown), Jing Tao, Xin‐Yuan Guan	0
2	Optimizing the nested PCR method for Decapod iridescent virus 1 (DIV1) targeting ATPase gene by reselecting the inner primers 2024 ·Journal of Invertebrate Pathology ·(unknown), Anqi Li, Xiaomeng Guo, (unknown), Xin‐Yuan Guan, Liang Qiu, Qingli Zhang, Jie Huang	2
3	HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer 2024 ·Journal of Experimental & Clinical Cancer Research ·Daqin Suo, Xiaoling Gao, Qingyun Chen, Tingting Zeng, (unknown), Guanghui Li, Yinli Zheng, Senlin Zhu, Jing‐Ping Yun, Xin‐Yuan Guan, Yan Li	10
4	Theoretical predictions of high-performance dual-atom alloys for the decomposition of formic acid 2024 ·Materials Today Sustainability ·Xin‐Yuan Guan, Wang Gao, Meiling Xiao, Changpeng Liu, Wei Xing	1
5	Whole-genome analysis of the benzoic acid-degrading bacterium Bacillus halotolerans B28 to reveal its phytoprobiotic effects 2023 ·International Biodeterioration & Biodegradation ·(unknown), Li Sun, Yu Hong, Chengkai Zhang, Xin‐Yuan Guan, Meng‐Liang Wang, Rui Cheng, C. Wang, Zhihong Xie	7
6	A neural‐related gene risk score for head and neck squamous cell carcinoma 2022 ·Oral Diseases ·(unknown), Wei‐fa Yang, Wang‐Yong Zhu, (unknown), Kar Yan Li, Xin‐Yuan Guan, Yu‐Xiong Su	5
7	ORAI2 Promotes Gastric Cancer Tumorigenicity and Metastasis through PI3K/Akt Signaling and MAPK-Dependent Focal Adhesion Disassembly 2020 ·Cancer Research ·(unknown), (unknown), Jiao Huang, Feifei Zhang, Zhaojie Lv, Yongxu Jia, (unknown), Liang-Zhan Sun, Ying Wang, Ying Tang, Krista R. Verhoeft, Yan Li, Yanru Qin, Xiang Lin, Xin‐Yuan Guan, Ka-On Lam	86
8	PDSS2 Deficiency Induces Hepatocarcinogenesis by Decreasing Mitochondrial Respiration and Reprogramming Glucose Metabolism 2018 ·Cancer Research ·Yan Li, Shuhai Lin, Lei Li, Zhi Tang, Yumin Hu, Xiaojiao Ban, Tingting Zeng, Ying Zhou, Ying‐Hui Zhu, Song Gao, Wen Deng, Xiaoshi Zhang, Dan Xie, Yunfei Yuan, Peng Huang, Jinjun Li, Zongwei Cai, Xin‐Yuan Guan	34
9	CSTF2-Induced Shortening of the RAC1 3′UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder 2018 ·Cancer Research ·Xin Chen, Jiaxing Zhang, Junhang Luo, Song Wu, (unknown), Ning-Fang Ma, Yong Feng, Mu-Yan Cai, (unknown), Jun Lü, (unknown), Jie-Wei Chen, Xiao-Han Jin, Hailiang Liu, Wei Chen, Xin‐Yuan Guan, Tiebang Kang, Fangjian Zhou, Dan Xie	55
10	TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma 2017 ·Cancer Research ·(unknown), Lok-Hei Chan, Stella Chai, Man Tong, Xin‐Yuan Guan, Nikki P. Lee, Yunfei Yuan, Dan Xie, Terence K. Lee, Nelson Dusetti, Alice Carrier, Stephanie Ma	42
11	A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma 2013 ·Gut ·Tim Hon Man Chan, Chi Ho Lin, Lihua Qi, Jing Fei, Yan Li, Kol Jia Yong, Ming Liu, Yangyang Song, (unknown), Vanessa Hui En Ng, Yunfei Yuan, Daniel G. Tenen, Xin‐Yuan Guan, Leilei Chen	186
12	A CD90+ Tumor-Initiating Cell Population with an Aggressive Signature and Metastatic Capacity in Esophageal Cancer 2013 ·Cancer Research ·Kwan Ho Tang, Yong Dai, Man Tong, Yuen Piu Chan, Pak Shing Kwan, Li Fu, Yan Qin, Sai Wah Tsao, Hong Lok Lung, Maria Li Lung, Daniel King Hung Tong, Simon Law, Kwok Wah Chan, Stephanie Ma, Xin‐Yuan Guan	128
13	Downregulation of the Novel Tumor Suppressor DIRAS1 Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma 2013 ·Cancer Research ·(unknown), Li Fu, Leilei Chen, Yanru Qin, Haibo Liu, Fajun Xie, Tingting Zeng, Sui-Sui Dong, Jiangchao Li, Yan Li, Yongdong Dai, Dan Xie, Xin‐Yuan Guan	51
14	Rab25 Is a Tumor Suppressor Gene with Antiangiogenic and Anti-Invasive Activities in Esophageal Squamous Cell Carcinoma 2012 ·Cancer Research ·Man Tong, Kwok Wah Chan, Jessie Y.J. Bao, Kai Yau Wong, Jinna Chen, Pak Shing Kwan, Kwan Ho Tang, Li Fu, Yanru Qin, Si Lok, Xin‐Yuan Guan, Stephanie Ma	96
15	MicroRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2 2011 ·Cancer Research ·Stephanie Ma, Yuen Piu Chan, Pak Shing Kwan, Terence K. Lee, Mingxia Yan, Kwan Ho Tang, (unknown), Juergen R. Vielkind, Xin‐Yuan Guan, Kwok Wah Chan	5
16	Downregulation of RBMS3 Is Associated with Poor Prognosis in Esophageal Squamous Cell Carcinoma 2011 ·Cancer Research ·Yan Li, Leilei Chen, (unknown), Tingting Zeng, Haibo Liu, Xueying Mao, Yanru Qin, Ying-Hui Zhu, Li Fu, Xin‐Yuan Guan	48
17	Characterization of Tumor-Suppressive Function of SOX6 in Human Esophageal Squamous Cell Carcinoma 2010 ·Clinical Cancer Research ·Yanru Qin, Hong Tang, Fajun Xie, Haibo Liu, Ying‐Hui Zhu, (unknown), Leilei Chen, Yan Li, Dora L.�W. Kwong, Li Fu, Xin‐Yuan Guan	57
18	Transforming Growth Factor β1 Promotes Chromosomal Instability in Human Papillomavirus 16 E6E7–Infected Cervical Epithelial Cells 2008 ·Cancer Research ·Wen Deng, Sai Wah Tsao, Yvonne K. Kwok, (unknown), Xiao Ru Huang, Si Liu, Chi Man Tsang, Hys Ngan, Any Cheung, Hui Y. Lan, Xin‐Yuan Guan, Annie L.M. Cheung	33
19	High-throughput Loss-of-Heterozygosity Study of Chromosome 3p in Lung Cancer Using Single-Nucleotide Polymorphism Markers 2006 ·Cancer Research ·(unknown), (unknown), (unknown), Daniel Chua, Mandy Ng, Li Fu, Kevin Chu, Yan Fang, You‐Qiang Song, Muhan Chen, Minyue Zhang, Pak C. Sham, Xin‐Yuan Guan	47
20	Array-Based Comparative Genomic Hybridization Analysis Identified Cyclin D1 as a Target Oncogene at 11q13.3 in Nasopharyngeal Carcinoma 2005 ·Cancer Research ·Angela B. Hui, (unknown), (unknown), Raymond King‐Yin Tsang, Ka‐Fai To, Xin‐Yuan Guan, (unknown), (unknown), (unknown), C. Andrew van Hasselt, Wen-Lin Kuo, Joe W. Gray, Dolly P. Huang, Kwok Wai Lo	89

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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