Junjie Chen

43.3k total citations · 14 hit papers
387 papers, 32.5k citations indexed

About

Junjie Chen is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Junjie Chen has authored 387 papers receiving a total of 32.5k indexed citations (citations by other indexed papers that have themselves been cited), including 301 papers in Molecular Biology, 122 papers in Oncology and 68 papers in Cancer Research. Recurrent topics in Junjie Chen's work include DNA Repair Mechanisms (164 papers), Cancer-related Molecular Pathways (67 papers) and CRISPR and Genetic Engineering (47 papers). Junjie Chen is often cited by papers focused on DNA Repair Mechanisms (164 papers), Cancer-related Molecular Pathways (67 papers) and CRISPR and Genetic Engineering (47 papers). Junjie Chen collaborates with scholars based in United States, China and South Korea. Junjie Chen's co-authors include Irene M. Ward, Xiaochun Yu, Michael S.Y. Huen, Zhenkun Lou, Ja‐Eun Kim, Wenqi Wang, Jingsong Yuan, Kay Minn, Shirley M.-H. Sy and Claudia C.S. Chini and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Junjie Chen

380 papers receiving 32.2k citations

Hit Papers

Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells 1997 2026 2006 2016 1997 2001 2007 2006 1997 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells
    1997 1.2k citations Junjie Chen et al. profile →
  2. Histone H2AX Is Phosphorylated in an ATR-dependent Manner in Response to Replicational Stress
    2001 936 citations Junjie Chen et al. Journal of Biological Chemistry profile →
  3. RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly
    2007 821 citations Xiaochun Yu, Junjie Chen et al. profile →
  4. Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair
    2006 765 citations Junjie Chen, Georges Mer et al. profile →
  5. Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage
    1997 748 citations Junjie Chen et al. profile →
  6. BAP1 links metabolic regulation of ferroptosis to tumour suppression
    2018 743 citations Xiaoguang Liu, Yongkun Wei et al. Nature Cell Biology profile →
  7. The BRCT Domain Is a Phospho-Protein Binding Domain
    2003 678 citations Xiaochun Yu, Claudia C.S. Chini et al. Science profile →
  8. Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis
    2023 648 citations Xiaoguang Liu, Litong Nie et al. Nature Cell Biology profile →
  9. METTL3-mediated m 6 A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance
    2019 629 citations Junjie Chen et al. profile →
  10. Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α
    2010 628 citations Junjie Chen et al. profile →
  11. DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1
    2002 562 citations Junjie Chen et al. Nature Cell Biology profile →
  12. mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation
    2021 533 citations Litong Nie, Xiaoguang Liu et al. profile →
  13. AMPK modulates Hippo pathway activity to regulate energy homeostasis
    2015 433 citations Wenqi Wang, Xu Li et al. Nature Cell Biology profile →
  14. Biological and clinical aspects of HPV-related cancers
    2020 227 citations Junjie Chen et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Junjie Chen United States 93 26.9k 9.8k 6.6k 4.5k 4.0k 387 32.5k
Christoph Lengauer United States 66 22.3k 0.8× 11.7k 1.2× 7.4k 1.1× 5.7k 1.3× 4.0k 1.0× 129 31.7k
Alan D. D’Andrea United States 98 25.3k 0.9× 11.2k 1.2× 6.7k 1.0× 2.9k 0.6× 5.1k 1.3× 313 32.7k
Kristian Helin Denmark 103 31.3k 1.2× 9.1k 0.9× 4.8k 0.7× 2.0k 0.4× 4.6k 1.2× 275 37.0k
Yue Xiong United States 91 24.3k 0.9× 11.3k 1.2× 5.4k 0.8× 5.0k 1.1× 2.2k 0.6× 254 34.2k
Michael B. Kastan United States 77 30.5k 1.1× 18.4k 1.9× 8.3k 1.3× 4.0k 0.9× 2.6k 0.6× 156 39.1k
Nikola P. Pavletich United States 65 25.2k 0.9× 9.2k 0.9× 3.9k 0.6× 3.6k 0.8× 2.7k 0.7× 79 30.0k
Xin‐Yuan Guan China 85 18.3k 0.7× 7.9k 0.8× 8.7k 1.3× 1.7k 0.4× 3.6k 0.9× 645 28.7k
Sanford D. Markowitz United States 82 20.3k 0.8× 12.4k 1.3× 8.4k 1.3× 2.6k 0.6× 3.4k 0.9× 239 32.1k
Carol Prives United States 84 25.6k 1.0× 20.9k 2.1× 6.2k 0.9× 2.7k 0.6× 2.6k 0.6× 218 33.7k
Geoffrey M. Wahl United States 80 21.7k 0.8× 11.1k 1.1× 4.8k 0.7× 2.6k 0.6× 4.3k 1.1× 178 30.1k

Countries citing papers authored by Junjie Chen

Since Specialization
Citations

This map shows the geographic impact of Junjie Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Junjie Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Junjie Chen more than expected).

Fields of papers citing papers by Junjie Chen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Junjie Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Junjie Chen. The network helps show where Junjie Chen may publish in the future.

Co-authorship network of co-authors of Junjie Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Junjie Chen. A scholar is included among the top collaborators of Junjie Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Junjie Chen. Junjie Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Liu, Mi, et al.. (2025). Extracellular vesicles: messengers of cross-talk between gastric cancer cells and the tumor microenvironment. Frontiers in Cell and Developmental Biology. 13. 1561856–1561856. 1 indexed citations
2.
Xiong, Yan-Bin, Junjie Chen, Tianyi Xie, et al.. (2024). Sintering activation energy and low-temperature sinterable process of Boron-lanthanide glass/Li2Zn3Ti4O12 ceramic composite systems for LTCC technology. Ceramics International. 50(24). 52797–52807. 2 indexed citations
3.
Yin, Ling, Xiaoding Hu, Guangsheng Pei, et al.. (2024). Genome-wide CRISPR screen reveals the synthetic lethality between BCL2L1 inhibition and radiotherapy. Life Science Alliance. 7(4). e202302353–e202302353. 4 indexed citations
4.
Liu, Xiaoguang, Zhen Chen, Yuelong Yan, et al.. (2024). Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis. Protein & Cell. 15(9). 686–703. 19 indexed citations
5.
Chen, Junjie, et al.. (2023). Mitochondria in cancer stem cells: Achilles heel or hard armor. Trends in Cell Biology. 33(8). 708–727. 42 indexed citations
6.
Azizian, Nancy G., Delaney K. Sullivan, Litong Nie, et al.. (2020). Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo. Journal of Proteome Research. 20(1). 858–866. 12 indexed citations
7.
Nie, Litong, Chao Wang, Nan Li, et al.. (2020). Proteome-wide Analysis Reveals Substrates of E3 Ligase RNF146 Targeted for Degradation. Molecular & Cellular Proteomics. 19(12). 2015–2030. 13 indexed citations
8.
Han, Han, Yuxuan Chen, Shiji Zhao, et al.. (2019). Elucidation of WW domain ligand binding specificities in the Hippo pathway reveals STXBP 4 as YAP inhibitor. The EMBO Journal. 39(1). e102406–e102406. 25 indexed citations
9.
Jung, Youn‐Sang, Wenqi Wang, Sohee Jun, et al.. (2018). Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin. Nature Cell Biology. 20(11). 1303–1314. 37 indexed citations
10.
Sorokin, Alexey V., Binoj C. Nair, Yongkun Wei, et al.. (2015). Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis. Cancer Research. 75(9). 1846–1858. 21 indexed citations
11.
Kavela, Sridhar, Swapnil Rohidas Shinde, Swarnalata Gowrishankar, et al.. (2012). PNUTS Functions as a Proto-Oncogene by Sequestering PTEN. Cancer Research. 73(1). 205–214. 41 indexed citations
12.
Kang, Zhigang, Junjie Chen, Yunkai Yu, et al.. (2011). Drozitumab, a Human Antibody to Death Receptor 5, Has Potent Antitumor Activity against Rhabdomyosarcoma with the Expression of Caspase-8 Predictive of Response. Clinical Cancer Research. 17(10). 3181–3192. 39 indexed citations
13.
Chen, Junjie, Steen Knudsen, Wiktor Mazin, Jesper Dahlgaard, & Baolin Zhang. (2011). A 71-Gene Signature of TRAIL Sensitivity in Cancer Cells. Molecular Cancer Therapeutics. 11(1). 34–44. 39 indexed citations
14.
Yoshida, Tatsushi, Yaqin Zhang, Leslie A. Rivera Rosado, et al.. (2010). Blockade of Rac1 Activity Induces G1 Cell Cycle Arrest or Apoptosis in Breast Cancer Cells through Downregulation of Cyclin D1, Survivin, and X-Linked Inhibitor of Apoptosis Protein. Molecular Cancer Therapeutics. 9(6). 1657–1668. 83 indexed citations
15.
Dray, Eloïse, Julia Etchin, Claudia Wiese, et al.. (2010). Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Nature Structural & Molecular Biology. 17(10). 1255–1259. 128 indexed citations
16.
Kim, Hongtae, Junjie Chen, & Xiaochun Yu. (2007). Ubiquitin-Binding Protein RAP80 Mediates BRCA1-Dependent DNA Damage Response. Science. 316(5828). 1202–1205. 455 indexed citations
17.
Huang, Haojie, Kevin M. Regan, Zhenkun Lou, Junjie Chen, & Donald J. Tindall. (2006). CDK2-Dependent Phosphorylation of FOXO1 as an Apoptotic Response to DNA Damage. Science. 314(5797). 294–297. 279 indexed citations
18.
Chini, Claudia C.S. & Junjie Chen. (2006). Repeated Phosphopeptide Motifs in Human Claspin Are Phosphorylated by Chk1 and Mediate Claspin Function. Journal of Biological Chemistry. 281(44). 33276–33282. 50 indexed citations
19.
Yu, Xiaochun, et al.. (2003). The BRCT Domain Is a Phospho-Protein Binding Domain. Science. 302(5645). 639–642. 678 indexed citations breakdown →
20.
Li, Ji, Junjie Chen, Fang Zhang, & Cui Zhang. (2000). Ebselen protection against hydrogen peroxide-induced cytotoxicity and DNA damage in HL-60 cells.. PubMed. 21(5). 455–9. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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