Michael R. Wester

2.8k total citations · 1 hit paper
18 papers, 2.4k citations indexed

About

Michael R. Wester is a scholar working on Pharmacology, Oncology and Computational Theory and Mathematics. According to data from OpenAlex, Michael R. Wester has authored 18 papers receiving a total of 2.4k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Pharmacology, 11 papers in Oncology and 7 papers in Computational Theory and Mathematics. Recurrent topics in Michael R. Wester's work include Pharmacogenetics and Drug Metabolism (18 papers), Drug Transport and Resistance Mechanisms (11 papers) and Computational Drug Discovery Methods (7 papers). Michael R. Wester is often cited by papers focused on Pharmacogenetics and Drug Metabolism (18 papers), Drug Transport and Resistance Mechanisms (11 papers) and Computational Drug Discovery Methods (7 papers). Michael R. Wester collaborates with scholars based in United States and France. Michael R. Wester's co-authors include Eric F. Johnson, Keith J. Griffin, G. Schoch, Jason K. Yano, C.D. Stout, C.D. Stout, Christine Yang, Patrick M. Dansette, Cristina Marques‐Soares and Daniel Mansuy and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Biochemistry.

In The Last Decade

Michael R. Wester

18 papers receiving 2.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-Å Resolution

2004 585 citations Jason K. Yano, Michael R. Wester et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michael R. Wester United States	15	1.9k	790	790	761	442	18	2.4k
José Cosme France	16	2.0k 1.0×	841 1.1×	754 1.0×	1.0k 1.3×	439 1.0×	24	2.8k
G. Schoch France	18	1.5k 0.8×	563 0.7×	729 0.9×	1.5k 1.9×	371 0.8×	21	2.8k
Jason K. Yano United States	20	1.9k 1.0×	1.0k 1.3×	1.1k 1.4×	1.6k 2.1×	466 1.1×	29	3.6k
Ken Korzekwa United States	27	2.2k 1.2×	1.6k 2.0×	461 0.6×	937 1.2×	377 0.9×	67	3.4k
Barry Jones United Kingdom	29	2.1k 1.1×	1.1k 1.4×	914 1.2×	1.1k 1.4×	583 1.3×	63	3.6k
Martha V. Martin United States	25	1.9k 1.0×	780 1.0×	232 0.3×	1.1k 1.5×	230 0.5×	36	2.9k
Ralph A. Stearns United States	27	1.3k 0.7×	590 0.7×	254 0.3×	715 0.9×	262 0.6×	68	2.5k
Hayley C. Angove United States	15	954 0.5×	475 0.6×	474 0.6×	745 1.0×	282 0.6×	16	2.4k
Gerald T. Miwa United States	34	2.1k 1.1×	1.0k 1.3×	235 0.3×	1.4k 1.8×	282 0.6×	75	4.0k
Irina F. Sevrioukova United States	33	1.6k 0.8×	569 0.7×	566 0.7×	1.8k 2.3×	355 0.8×	74	3.4k

Countries citing papers authored by Michael R. Wester

Since Specialization

Citations

This map shows the geographic impact of Michael R. Wester's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael R. Wester with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael R. Wester more than expected).

Fields of papers citing papers by Michael R. Wester

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael R. Wester. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael R. Wester. The network helps show where Michael R. Wester may publish in the future.

Co-authorship network of co-authors of Michael R. Wester

This figure shows the co-authorship network connecting the top 25 collaborators of Michael R. Wester. A scholar is included among the top collaborators of Michael R. Wester based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael R. Wester. Michael R. Wester is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

1.

Lee, Caroline A., Deepak Dalvie, Michael R. Wester, et al.. (2009). Identification of Novel Substrates for Human Cytochrome P450 2J2. Drug Metabolism and Disposition. 38(2). 347–356. 110 indexed citations

2.

Kang, Ping, Mingxiang Liao, Michael R. Wester, et al.. (2007). CYP3A4-Mediated Carbamazepine (CBZ) Metabolism: Formation of a Covalent CBZ-CYP3A4 Adduct and Alteration of the Enzyme Kinetic Profile. Drug Metabolism and Disposition. 36(3). 490–499. 50 indexed citations

3.

Yano, Jason K., Michael R. Wester, G. Schoch, et al.. (2004). The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-Å Resolution. Journal of Biological Chemistry. 279(37). 38091–38094. 585 indexed citations breakdown →

4.

Schoch, G., Jason K. Yano, Michael R. Wester, et al.. (2004). Structure of Human Microsomal Cytochrome P450 2C8. Journal of Biological Chemistry. 279(10). 9497–9503. 314 indexed citations

5.

Wester, Michael R., Jason K. Yano, G. Schoch, et al.. (2004). The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0-Å Resolution. Journal of Biological Chemistry. 279(34). 35630–35637. 361 indexed citations

6.

Wester, Michael R., Eric F. Johnson, Cristina Marques‐Soares, et al.. (2003). STRUCTURE OF MAMMALIAN CYTOCHROME P450 2C5 COMPLEXED WITH DICLOFENAC AT 2.Å RESOLUTION : EVIDENCE FOR AN INDUCED FIT MODEL OF SUBSTRATE BINDING. HAL (Le Centre pour la Communication Scientifique Directe). 1 indexed citations

7.

Wester, Michael R., Eric F. Johnson, Cristina Marques‐Soares, et al.. (2003). Structure of a Substrate Complex of Mammalian Cytochrome P450 2C5 at 2.3 Å Resolution: Evidence for Multiple Substrate Binding Modes^,. Biochemistry. 42(21). 6370–6379. 150 indexed citations

8.

Scott, Emily E., You Ai He, Michael R. Wester, et al.. (2003). An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution. Proceedings of the National Academy of Sciences. 100(23). 13196–13201. 298 indexed citations

9.

Wester, Michael R., Eric F. Johnson, Cristina Marques‐Soares, et al.. (2003). Structure of Mammalian Cytochrome P450 2C5 Complexed with Diclofenac at 2.1 Å Resolution: Evidence for an Induced Fit Model of Substrate Binding^,. Biochemistry. 42(31). 9335–9345. 144 indexed citations

10.

Marques‐Soares, Cristina, Sylvie Dijols, Michael R. Wester, et al.. (2003). Sulfaphenazole Derivatives as Tools for Comparing Cytochrome P450 2C5 and Human Cytochromes P450 2Cs: Identification of a New High Affinity Substrate Common to Those Enzymes. Biochemistry. 42(21). 6363–6369. 15 indexed citations

11.

Johnson, Eric F., Michael R. Wester, & C.D. Stout. (2002). THE STRUCTURE OF MICROSOMAL CYTOCHROME P450 2C5: A STEROID AND DRUG METABOLIZING ENZYME. Endocrine Research. 28(4). 435–441. 14 indexed citations

12.

Wester, Michael R., et al.. (2002). Purification and crystallization of N-terminally truncated forms of microsomal cytochrome P450 2C5. Methods in enzymology on CD-ROM/Methods in enzymology. 357. 73–79. 29 indexed citations

13.

Spatzenegger, Margit, et al.. (2001). Amino Acid Residues Critical for Differential Inhibition of CYP2B4, CYP2B5, and CYP2B1 by Phenylimidazoles. Molecular Pharmacology. 59(3). 475–484. 34 indexed citations

14.

Spatzenegger, Margit, et al.. (2001). Amino Acid Residues Critical for Differential Inhibition of CYP2B4, CYP2B5, and CYP2B1 by Phenylimidazoles. Molecular Pharmacology. 59(3). 475–484. 5 indexed citations

15.

Tsao, Cheng‐Chung, Michael R. Wester, Burhan I. Ghanayem, et al.. (2001). Identification of Human CYP2C19 Residues that Confer S-Mephenytoin 4‘-Hydroxylation Activity to CYP2C9. Biochemistry. 40(7). 1937–1944. 36 indexed citations

16.

Savas, Üzen, Michael R. Wester, Keith J. Griffin, & Eric F. Johnson. (2000). Rabbit Pregnane X Receptor Is Activated by Rifampicin. Drug Metabolism and Disposition. 28(5). 529–537. 42 indexed citations

17.

Wester, Michael R., Jerome M. Lasker, Eric F. Johnson, & Judy L. Raucy. (2000). CYP2C19 Participates in Tolbutamide Hydroxylation by Human Liver Microsomes. Drug Metabolism and Disposition. 28(3). 354–359. 60 indexed citations

18.

Lasker, Jerome M., et al.. (1998). Characterization of CYP2C19 and CYP2C9 from Human Liver: Respective Roles in Microsomal Tolbutamide,S-Mephenytoin, and Omeprazole Hydroxylations. Archives of Biochemistry and Biophysics. 353(1). 16–28. 124 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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