Keith J. Griffin

6.9k total citations · 1 hit paper
46 papers, 5.6k citations indexed

About

Keith J. Griffin is a scholar working on Pharmacology, Molecular Biology and Oncology. According to data from OpenAlex, Keith J. Griffin has authored 46 papers receiving a total of 5.6k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Pharmacology, 23 papers in Molecular Biology and 16 papers in Oncology. Recurrent topics in Keith J. Griffin's work include Pharmacogenetics and Drug Metabolism (27 papers), Drug Transport and Resistance Mechanisms (14 papers) and Peroxisome Proliferator-Activated Receptors (12 papers). Keith J. Griffin is often cited by papers focused on Pharmacogenetics and Drug Metabolism (27 papers), Drug Transport and Resistance Mechanisms (14 papers) and Peroxisome Proliferator-Activated Receptors (12 papers). Keith J. Griffin collaborates with scholars based in United States, United Kingdom and Austria. Keith J. Griffin's co-authors include Eric F. Johnson, Jason K. Yano, G. Schoch, Mei‐Hui Hsu, Michael R. Wester, Judy L. Raucy, C.D. Stout, C.D. Stout, Michael P. Manns and A. Scott Muerhoff and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Keith J. Griffin

46 papers receiving 5.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-Å Resolution

2004 585 citations Jason K. Yano, Michael R. Wester et al. Journal of Biological Chemistry profile →

Peers

Keith J. Griffin

PHARM

ONCOL

CTM

EPIDE

Tommy B. Andersson Sweden

Judy L. Raucy United States

Eric F. Johnson United States

Lance R. Pohl United States

Susumu Imaoka Japan

Thomas H. Rushmore United States

J. Brian Houston United Kingdom

Patrick M. Dansette France

John T. Moore United States

Jerome M. Lasker United States

Tommy B. Andersson Sweden

Keith J. Griffin

1.8k ×0.7

3.1k ×1.2

PHARM

1.9k ×1.4

ONCOL

612 ×0.7

CTM

479 ×0.7

EPIDE

Citations per year, relative to Keith J. Griffin Keith J. Griffin (= 1×) peers Tommy B. Andersson

Countries citing papers authored by Keith J. Griffin

Since Specialization

Citations

This map shows the geographic impact of Keith J. Griffin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Keith J. Griffin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Keith J. Griffin more than expected).

Fields of papers citing papers by Keith J. Griffin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Keith J. Griffin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Keith J. Griffin. The network helps show where Keith J. Griffin may publish in the future.

Co-authorship network of co-authors of Keith J. Griffin

This figure shows the co-authorship network connecting the top 25 collaborators of Keith J. Griffin. A scholar is included among the top collaborators of Keith J. Griffin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Keith J. Griffin. Keith J. Griffin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Zinnanti, William J., Jelena Lazović, Keith J. Griffin, et al.. (2008). Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease. Brain. 132(4). 903–918. 107 indexed citations

Sansen, Stefaan, Jason K. Yano, G. Schoch, et al.. (2007). Adaptations for the Oxidation of Polycyclic Aromatic Hydrocarbons Exhibited by the Structure of Human P450 1A2. Journal of Biological Chemistry. 282(19). 14348–14355. 392 indexed citations

Hsu, Mei‐Hui, Üzen Savas, Keith J. Griffin, & Eric F. Johnson. (2007). Human Cytochrome P450 Family 4 Enzymes: Function, Genetic Variation and Regulation. Drug Metabolism Reviews. 39(2-3). 515–538. 111 indexed citations

Hsu, Mei‐Hui, et al.. (2006). Regulation of Human Cytochrome P450 4F2 Expression by Sterol Regulatory Element-binding Protein and Lovastatin. Journal of Biological Chemistry. 282(8). 5225–5236. 43 indexed citations

Savas, Üzen, Mei‐Hui Hsu, Keith J. Griffin, David Bell, & Eric F. Johnson. (2005). Conditional regulation of the human CYP4X1 and CYP4Z1 genes. Archives of Biochemistry and Biophysics. 436(2). 377–385. 39 indexed citations

Yano, Jason K., et al.. (2005). Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen. Nature Structural & Molecular Biology. 12(9). 822–823. 245 indexed citations

Yano, Jason K., Michael R. Wester, G. Schoch, et al.. (2004). The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-Å Resolution. Journal of Biological Chemistry. 279(37). 38091–38094. 585 indexed citations breakdown →

Schoch, G., Jason K. Yano, Michael R. Wester, et al.. (2004). Structure of Human Microsomal Cytochrome P450 2C8. Journal of Biological Chemistry. 279(10). 9497–9503. 314 indexed citations

Wester, Michael R., Jason K. Yano, G. Schoch, et al.. (2004). The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0-Å Resolution. Journal of Biological Chemistry. 279(34). 35630–35637. 361 indexed citations

10.

Johnson, Eric F., Mei‐Hui Hsu, Üzen Savas, & Keith J. Griffin. (2002). Regulation of P450 4A expression by peroxisome proliferator activated receptors. Toxicology. 181-182. 203–206. 59 indexed citations

11.

Savas, Üzen, Michael R. Wester, Keith J. Griffin, & Eric F. Johnson. (2000). Rabbit Pregnane X Receptor Is Activated by Rifampicin. Drug Metabolism and Disposition. 28(5). 529–537. 42 indexed citations

12.

Savas, Üzen, Keith J. Griffin, & Eric F. Johnson. (1999). Molecular Mechanisms of Cytochrome P-450 Induction by Xenobiotics: An Expanded Role for Nuclear Hormone Receptors. Molecular Pharmacology. 56(5). 851–857. 89 indexed citations

13.

Jung, Frank, et al.. (1998). Identification of Amino Acid Substitutions that Confer a High Affinity for Sulfaphenazole Binding and a High Catalytic Efficiency for Warfarin Metabolism To P450 2C19. Biochemistry. 37(46). 16270–16279. 43 indexed citations

14.

Richardson, Toby H., Keith J. Griffin, Frank Jung, Judy L. Raucy, & Eric F. Johnson. (1997). Targeted Antipeptide Antibodies to Cytochrome P450 2C18 Based on Epitope Mapping of an Inhibitory Monoclonal Antibody to P450 2C51. Archives of Biochemistry and Biophysics. 338(2). 157–164. 30 indexed citations

15.

Roman, L. J., J.E. Clark, A. Scott Muerhoff, et al.. (1993). Expression of Rabbit Cytochromes P4504A Which Catalyze the ω-Hydroxylation of Arachidonic Acid, Fatty Acids, and Prostaglandins. Archives of Biochemistry and Biophysics. 307(1). 57–65. 63 indexed citations

16.

Griffin, Keith J., et al.. (1993). Rabbit Prostaglandin ω-Hydroxylase (CYP4A4): Gene Structure and Expression. Archives of Biochemistry and Biophysics. 300(2). 670–676. 16 indexed citations

17.

Griffin, Keith J., et al.. (1992). Opioid peptides are substrates for the bifunctional enzyme LTA4 hydrolase/aminopeptidase. Prostaglandins. 44(3). 251–257. 29 indexed citations

18.

Manns, Michael P., Keith J. Griffin, Linda C. Quattrochi, et al.. (1990). Identification of cytochrome P450IA2 as a human autoantigen. Archives of Biochemistry and Biophysics. 280(1). 229–232. 45 indexed citations

19.

Johnson, Eric F., Duard L. Walker, Keith J. Griffin, et al.. (1990). Cloning and expression of three rabbit kidney cDNAs encoding lauric acid .omega.-hydroxylases. Biochemistry. 29(4). 873–879. 55 indexed citations

20.

Manns, Michael P., Eric F. Johnson, Keith J. Griffin, Eng M. Tan, & Kevin F. Sullivan. (1989). Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1.. Journal of Clinical Investigation. 83(3). 1066–1072. 275 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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