You Ai He

1.2k total citations
15 papers, 1.1k citations indexed

About

You Ai He is a scholar working on Pharmacology, Spectroscopy and Molecular Biology. According to data from OpenAlex, You Ai He has authored 15 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Pharmacology, 6 papers in Spectroscopy and 5 papers in Molecular Biology. Recurrent topics in You Ai He's work include Pharmacogenetics and Drug Metabolism (14 papers), Analytical Chemistry and Chromatography (5 papers) and Computational Drug Discovery Methods (5 papers). You Ai He is often cited by papers focused on Pharmacogenetics and Drug Metabolism (14 papers), Analytical Chemistry and Chromatography (5 papers) and Computational Drug Discovery Methods (5 papers). You Ai He collaborates with scholars based in United States, China and South Korea. You Ai He's co-authors include James R. Halpert, Emily E. Scott, Eric F. Johnson, Mark A. White, You He, Grażyna D. Szklarz, C.D. Stout, Michael R. Wester, Christopher C.Q. Chin and C.D. Stout and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and The Journal of Clinical Endocrinology & Metabolism.

In The Last Decade

You Ai He

15 papers receiving 1.1k citations

Peers

You Ai He

PHARM

ONCOL

CTM

SPECT

T D Porter United States

Tammy L. Domanski United States

Jan L. Wahlstrom United States

Peter Hlavica Germany

Sylvie Dijols France

Kirk R. Henne United States

Kishore K. Khan United States

T. Baba Japan

Shawn Harriman United States

Sharon L. Ripp United States

T D Porter United States

You Ai He

855 ×1.0

PHARM

609 ×1.6

379 ×1.0

ONCOL

121 ×0.4

CTM

107 ×0.5

SPECT

Citations per year, relative to You Ai He You Ai He (= 1×) peers T D Porter

Countries citing papers authored by You Ai He

Since Specialization

Citations

This map shows the geographic impact of You Ai He's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by You Ai He with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites You Ai He more than expected).

Fields of papers citing papers by You Ai He

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by You Ai He. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by You Ai He. The network helps show where You Ai He may publish in the future.

Co-authorship network of co-authors of You Ai He

This figure shows the co-authorship network connecting the top 25 collaborators of You Ai He. A scholar is included among the top collaborators of You Ai He based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with You Ai He. You Ai He is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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15 of 15 papers shown

He, You Ai, et al.. (2019). Effect of introducing disulfide bridges in C-terminal structure on the thermostability of xylanase XynZF-2 from <i>Aspergillus niger</i>. The Journal of General and Applied Microbiology. 65(5). 240–245. 5 indexed citations

Gupta, Ram P., You Ai He, Kennerly S. Patrick, James R. Halpert, & Norman H. Bell. (2005). CYP3A4 Is a Vitamin D-24- and 25-Hydroxylase: Analysis of Structure Function by Site-Directed Mutagenesis. The Journal of Clinical Endocrinology & Metabolism. 90(2). 1210–1219. 82 indexed citations

Yamaguchi, Yoshitaka, Kishore K. Khan, You Ai He, You He, & James R. Halpert. (2004). TOPOLOGICAL CHANGES IN THE CYP3A4 ACTIVE SITE PROBED WITH PHENYLDIAZENE: EFFECT OF INTERACTION WITH NADPH-CYTOCHROME P450 REDUCTASE AND CYTOCHROME B5 AND OF SITE-DIRECTED MUTAGENESIS. Drug Metabolism and Disposition. 32(1). 155–161. 20 indexed citations

Scott, Emily E., Mark A. White, You Ai He, et al.. (2004). Structure of Mammalian Cytochrome P450 2B4 Complexed with 4-(4-Chlorophenyl)imidazole at 1.9-Å Resolution. Journal of Biological Chemistry. 279(26). 27294–27301. 255 indexed citations

Scott, Emily E., You Ai He, Michael R. Wester, et al.. (2003). An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution. Proceedings of the National Academy of Sciences. 100(23). 13196–13201. 298 indexed citations

He, You Ai, et al.. (2002). Analysis of homotropic and heterotropic cooperativity of diazepam oxidation by CYP3A4 using site-directed mutagenesis and kinetic modeling. Archives of Biochemistry and Biophysics. 409(1). 92–101. 65 indexed citations

Khan, Kishore K., You Ai He, You He, & James R. Halpert. (2002). Site-Directed Mutagenesis of Cytochrome P450eryF: Implications for Substrate Oxidation, Cooperativity, and Topology of the Active Site. Chemical Research in Toxicology. 15(6). 843–853. 20 indexed citations

Waller, Stephen, You Ai He, Greg R. Harlow, et al.. (1999). 2,2‘,3,3‘,6,6‘-Hexachlorobiphenyl Hydroxylation by Active Site Mutants of Cytochrome P450 2B1 and 2B11. Chemical Research in Toxicology. 12(8). 690–699. 57 indexed citations

Harlow, Greg R., You Ai He, & James R. Halpert. (1997). Functional interaction between amino-acid residues 242 and 290 in cytochromes P-450 2B1 and 2B11. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1338(2). 259–266. 27 indexed citations

10.

He, You Ai, You He, Grażyna D. Szklarz, & James R. Halpert. (1997). Identification of Three Key Residues in Substrate Recognition Site 5 of Human Cytochrome P450 3A4 by Cassette and Site-Directed Mutagenesis. Biochemistry. 36(29). 8831–8839. 78 indexed citations

11.

He, Kan, You Ai He, Grażyna D. Szklarz, James R. Halpert, & Maria Almira Correia. (1996). Secobarbital-mediated Inactivation of Cytochrome P450 2B1 and Its Active Site Mutants. Journal of Biological Chemistry. 271(42). 25864–25872. 25 indexed citations

12.

Liu, Juping, You Ai He, & James R. Halpert. (1996). Role of Residue 480 in Substrate Specificity of Cytochrome P450 2B5 and 2B11. Archives of Biochemistry and Biophysics. 327(1). 167–173. 14 indexed citations

13.

He, You, You Ai He, & James R. Halpert. (1995). Escherichia coli Expression of Site-Directed Mutants of Cytochrome P450 2B1 from Six Substrate Recognition Sites: Substrate Specificity and Inhibitor Selectivity Studies. Chemical Research in Toxicology. 8(4). 574–579. 61 indexed citations

14.

Szklarz, Grażyna D., You Ai He, & James R. Halpert. (1995). Site-Directed Mutagenesis as a Tool for Molecular Modeling of Cytochrome P450 2B1. Biochemistry. 34(44). 14312–14322. 74 indexed citations

15.

He, You Ai, Celia A. Balfour, Karen M. Kedzie, & James R. Halpert. (1992). Role of residue 478 as a determinant of the substrate specificity of cytochrome P450 2B1. Biochemistry. 31(38). 9220–9226. 51 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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