Andreas Plückthun

41.9k total citations · 9 hit papers
481 papers, 32.3k citations indexed

About

Andreas Plückthun is a scholar working on Molecular Biology, Radiology, Nuclear Medicine and Imaging and Genetics. According to data from OpenAlex, Andreas Plückthun has authored 481 papers receiving a total of 32.3k indexed citations (citations by other indexed papers that have themselves been cited), including 408 papers in Molecular Biology, 264 papers in Radiology, Nuclear Medicine and Imaging and 57 papers in Genetics. Recurrent topics in Andreas Plückthun's work include Monoclonal and Polyclonal Antibodies Research (264 papers), Glycosylation and Glycoproteins Research (115 papers) and RNA and protein synthesis mechanisms (95 papers). Andreas Plückthun is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (264 papers), Glycosylation and Glycoproteins Research (115 papers) and RNA and protein synthesis mechanisms (95 papers). Andreas Plückthun collaborates with scholars based in Switzerland, Germany and United States. Andreas Plückthun's co-authors include Annemarie Honegger, Jozef Hanes, Hans Binz, Arne Skerra, Patrick Amstutz, Patrik Forrer, Achim Knappik, Andrew Bradbury, Lutz Jermutus and Christian Zahnd and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Andreas Plückthun

476 papers receiving 31.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

In vitroselection and evolution of functional proteins by using ribosome display

1997 842 citations Jozef Hanes, Andreas Plückthun Proceedings of the National Academy of Sciences profile →
Assembly of a Functional Immunoglobulin F _v Fragment in Escherichia coli

1988 759 citations Andreas Plückthun et al. profile →
Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes

1998 656 citations Andreas Plückthun et al. profile →
Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides 1 1Edited by I. A. Wilson

2000 568 citations Andreas Plückthun et al. profile →
Engineering novel binding proteins from nonimmunoglobulin domains

2005 516 citations Hans Binz, Andreas Plückthun et al. profile →
High-affinity binders selected from designed ankyrin repeat protein libraries

2004 512 citations Hans Binz, A. Kohl et al. profile →
In vitrogenerated antibodies specific for telomeric guanine-quadruplex DNA react withStylonychia lemnaemacronuclei

2001 512 citations Christiane Schaffitzel, Jozef Hanes et al. Proceedings of the National Academy of Sciences profile →
Reproducibility: Standardize antibodies used in research

2015 470 citations Andreas Plückthun et al. profile →
Designed Ankyrin Repeat Proteins (DARPins): Binding Proteins for Research, Diagnostics, and Therapy

2011 448 citations Andreas Plückthun profile →

Peers

Countries citing papers authored by Andreas Plückthun

Since Specialization

Citations

This map shows the geographic impact of Andreas Plückthun's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andreas Plückthun with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andreas Plückthun more than expected).

Fields of papers citing papers by Andreas Plückthun

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andreas Plückthun. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andreas Plückthun. The network helps show where Andreas Plückthun may publish in the future.

Co-authorship network of co-authors of Andreas Plückthun

This figure shows the co-authorship network connecting the top 25 collaborators of Andreas Plückthun. A scholar is included among the top collaborators of Andreas Plückthun based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andreas Plückthun. Andreas Plückthun is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2 2024 ·Journal of Biological Chemistry ·(unknown), (unknown), Eva Karasmanis, Kathryn S. Hatch, Deep Chatterjee, (unknown), Kamal R. Abdul Azeez, (unknown), (unknown), Birgit Dreier, Andreas Plückthun, Wim Versées, Sebastian Mathea, Andrés E. Leschziner, Samara L. Reck‐Peterson, Stefan Knapp	1
2	FAP-retargeted Ad5 enables in vivo gene delivery to stromal cells in the tumor microenvironment 2023 ·Molecular Therapy ·K. Patricia Hartmann, Merel van Gogh, (unknown), (unknown), Gabriela Nagy‐Davidescu, Lubor Borsig, Andreas Plückthun	9
3	DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma 2023 ·Cell Death and Disease ·Alexander Strubel, (unknown), Oliver Hartmann, A. Chaikuad, Birgit Dreier, Jonas V. Schaefer, Jakob Gebel, Christian Osterburg, Marcel Tuppi, Birgit Schäfer, (unknown), Mathias T. Rosenfeldt, Stefan Knapp, Andreas Plückthun, Markus E. Diefenbacher, Volker Dötsch	7
4	Structures of neurokinin 1 receptor in complex with G _q and G _s proteins reveal substance P binding mode and unique activation features 2021 ·Science Advances ·(unknown), Janosch Ehrenmann, (unknown), (unknown), Jendrik Schöppe, Ohad Medalia, Andreas Plückthun	35
5	The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody 2021 ·Proceedings of the National Academy of Sciences ·Sheena N. Smith, Rajib Schubert, (unknown), (unknown), Markus Schmid, Niels Kirk, (unknown), Viviana Gradinaru, Andreas Plückthun	19
6	Probing the Conformation States of Neurotensin Receptor 1 Variants by NMR Site‐Directed Methyl Labeling 2020 ·ChemBioChem ·(unknown), (unknown), (unknown), Matthias Hillenbrand, Andreas Plückthun, Franz Hagn	17
7	High-Throughput Generation of Bispecific Binding Proteins by Sortase A–Mediated Coupling for Direct Functional Screening in Cell Culture 2019 ·Molecular Cancer Therapeutics ·(unknown), Martin Schwill, Ykelien L. Boersma, Andreas Plückthun	9
8	Multispecific Targeting with Synthetic Ankyrin Repeat Motif Chimeric Antigen Receptors 2019 ·Clinical Cancer Research ·Ashwini Balakrishnan, Anusha Rajan, Alexander I. Salter, Paula L. Kosasih, Qian Wu, Jenna Voutsinas, Michael C. Jensen, Andreas Plückthun, Stanley R. Riddell	48
9	Insight into microtubule nucleation from tubulin-capping proteins 2019 ·Proceedings of the National Academy of Sciences ·Valérie Campanacci, Agathe Urvoas, (unknown), Magali Aumont‐Nicaise, Ana‐Andreea Arteni, Christophe Velours, Marie Valerio‐Lepiniec, Birgit Dreier, Andreas Plückthun, Antoine Pilon, Christian Poüs, Philippe Minard, Benoı̂t Gigant	17
10	DARPins recognizing mTFP1 as novel reagents for in vitro and in vivo protein manipulations 2018 ·Biology Open ·M Viganò, (unknown), Jonas V. Schaefer, Roman P. Jakob, Shinya Matsuda, Timm Maier, Andreas Plückthun, Markus Affolter	10
11	A quantitative comparison of cytosolic delivery via different protein uptake systems 2017 ·Scientific Reports ·Wouter P. R. Verdurmen, (unknown), Andreas Plückthun	67
12	Conformational dynamics of a G-protein α subunit is tightly regulated by nucleotide binding 2016 ·Proceedings of the National Academy of Sciences ·(unknown), Ralf Stehle, Pascal Egloff, Simina Grigoriu, Andreas Plückthun, Gerhard Wagner, Franz Hagn	79
13	Increasing the Antitumor Effect of an EpCAM-Targeting Fusion Toxin by Facile Click PEGylation 2013 ·Molecular Cancer Therapeutics ·Manuel Simon, Norbert Stefan, Lubor Borsig, Andreas Plückthun, Uwe Zangemeister‐Wittke	33
14	Directed Evolution of G-Protein-Coupled Receptors for High Functional Expression and Detergent Stability 2013 ·Methods in enzymology on CD-ROM/Methods in enzymology ·(unknown), Andreas Plückthun	16
15	Efficient Tumor Targeting with High-Affinity Designed Ankyrin Repeat Proteins: Effects of Affinity and Molecular Size 2010 ·Cancer Research ·Christian Zahnd, (unknown), Michael T. Stumpp, (unknown), Rastislav Tamaskovic, Gabriela Nagy‐Davidescu, Birgit Dreier, Roger Schibli, Hans Binz, Robert Waibel, Andreas Plückthun	208
16	A Novel Fusion Toxin Derived from an EpCAM-Specific Designed Ankyrin Repeat Protein Has Potent Antitumor Activity 2010 ·Clinical Cancer Research ·(unknown), Norbert Stefan, Sacha I. Rothschild, Andreas Plückthun, Uwe Zangemeister‐Wittke	76
17	EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteins 2009 ·Molecular Cancer Therapeutics ·Johannes Winkler, (unknown), Andreas Plückthun, Uwe Zangemeister‐Wittke	71
18	Directed evolution of a G protein-coupled receptor for expression, stability, and binding selectivity 2008 ·Proceedings of the National Academy of Sciences ·Casim A. Sarkar, Igor Dodevski, Manca Kenig, Stefan Dudli, (unknown), Emmanuel Hermans, Andreas Plückthun	157
19	Designed to be stable: Crystal structure of a consensus ankyrin repeat protein 2003 ·Proceedings of the National Academy of Sciences ·A. Kohl, Hans Binz, Patrik Forrer, Michael T. Stumpp, Andreas Plückthun, Markus G. Grütter	213
20	In vitro selection and evolution of proteins 2001 ·Advances in protein chemistry ·Andreas Plückthun, Christiane Schaffitzel, Jozef Hanes, Lutz Jermutus	42

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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