Margaret Wu

11.9k citations

56 papers · 8.7k indexed · 2 hit papers · h-index 30

Impact in

Endocrinology, Diabetes and Metabolism top 0.5%
- Diabetes Treatment and Management
- Diet, Metabolism, and Disease
Physiology top 0.5%
- Adipose Tissue and Metabolism

Papers in

Biochemistry 9
Physiology 19
- Adipose Tissue and Metabolism 16

Co-authors: Thomas W. Doebber David E. Moller John Ventre Gaochao Zhou Yuli Chen Judy Fenyk‐Melody Laurie J. Goodyear Nobuharu Fujii
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Clinical Investigation (5 papers)Biochemical and Biophysical Research Communications (5 papers)Journal of Medicinal Chemistry (4 papers)Endocrinology (3 papers)
Partner nations: United States Australia Tunisia

In The Last Decade

Margaret Wu

55 papers receiving 8.4k citations

Hit Papers

align trajectories log scale

Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity 2004 · 978 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2004 Journal of Biological Chemistry
2001 Journal of Clinical Investigation

Peers

Countries citing papers authored by Margaret Wu

Since Specialization

Citations

This map shows the geographic impact of Margaret Wu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Margaret Wu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Margaret Wu more than expected).

Fields of papers citing papers by Margaret Wu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Margaret Wu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Margaret Wu. The network helps show where Margaret Wu may publish in the future.

Co-authors

The 25 scholars most cited alongside Margaret Wu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Margaret Wu Line = papers co-authored together Margaret Wu links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones Molecular Metabolism ·Olga Rudenko, Jin Shang, Alexander Munk, Jeppe H. Ekberg, Natalia Petersen, Maja S. Engelstoft, Kristoffer L. Egerod, Siv A. Hjorth, Margaret Wu, Yue Feng, Yunping Zhou, Jacek Mokrosiński, Peter Thams, Frank Reimann, Fiona M. Gribble, Jens F. Rehfeld, Jens J. Holst, Jonas T. Treebak, Andrew D. Howard, Thue W. Schwartz	2018	47
2	The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys PLoS ONE ·Sheo B. Singh, Ling Kang, Andrea R. Nawrocki, Dan Zhou, Margaret Wu, Stephen F. Previs, Corey Miller, Haiying Liu, Catherine D. G. Hines, Maria Madeira, Jin Cao, Kithsiri Herath, Liangsu Wang, David E. Kelley, Cai Li, Hong-Ping Guan	2016	17
3	Potentiation of Insulin-Mediated Glucose Lowering without Elevated Hypoglycemia Risk by a Small Molecule Insulin Receptor Modulator PLoS ONE ·Margaret Wu, Ge Dai, Jun Yao, Scott Hoyt, Liangsu Wang, James Mu	2015	6
4	Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities Bioorganic & Medicinal Chemistry Letters ·Haifeng Tang, Yan Yan, Zhe Feng, Reynalda K. de Jesus, Lihu Yang, Dorothy Levorse, Karen Owens, Taro E. Akiyama, Raynald Bergeron, Gino Castriota, Thomas W. Doebber, Kenneth Ellsworth, Michael E. Lassman, Li Cai, Margaret Wu, Bei B. Zhang, Kevin T. Chapman, Sander G. Mills, Joel P. Berger, Alexander Pasternak	2010	13
5	Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo European Journal of Pharmacology ·Heather Zhou, Chen‐Ni Chin, Margaret Wu, Weihua Ni, Shuo Quan, Franklin Liu, Qing Dallas-Yang, Kenneth Ellsworth, Thu Ho, Aiwu Zhang, Tajneen Natasha, Jing Li, Kevin T. Chapman, William R. Strohl, Cai Li, I‐Ming Wang, Joel P. Berger, Zhiqiang An, Bei B. Zhang, Guoqiang Jiang	2009	28
6	A novel selective peroxisome proliferator-activator receptor-γ modulator—SPPARγM5 improves insulin sensitivity with diminished adverse cardiovascular effects European Journal of Pharmacology ·Ching H. Chang, Lesley A. McNamara, Margaret Wu, Eric S. Muise, Yejun Tan, Harold B. Wood, Peter T. Meinke, John R. Thompson, Tom Doebber, Joel P. Berger, Margaret E. McCann	2008	25
7	Highly functionalized 7-azaindoles as selective PPARγ modulators Bioorganic & Medicinal Chemistry Letters ·Sheryl D. Debenham, Audrey Chan, Fiona WaiYu Lau, Weiguo Liu, Harold B. Wood, Karen Lemme, Lawrence F. Colwell, Bahanu Habulihaz, Taro E. Akiyama, Monica Einstein, Thomas W. Doebber, Neelam Sharma, Chaunlin F. Wang, Margaret Wu, Joel P. Berger, Peter T. Meinke	2008	15
8	Kinetic analysis of the fatty acid synthesis pathway in HCT-116 colon cancer cells: role of FAS and ACC1 in maintaining tumor cell viability and proliferation Cancer Research ·Nicole Ginanni, Yanai Zhan, Michael R. Tota, Margaret Wu, Jennifer A. Roth, Dennis A. Ridenour, Peter R. Strack, Nathan Bays, Eric Bachman, Victoria M. Richon, Nancy E. Kohl, Stefan Krauß	2007	2
9	Surface enhanced laser desorption ionization spectrometry reveals biomarkers for drug treatment but not dose PROTEOMICS ·Cloud P. Paweletz, Matthew C. Wiener, Jeffrey R. Sachs, Roger Meurer, Margaret Wu, Kenney K. Wong, Nathan A. Yates, Ronald C. Hendrickson	2006	8
10	Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase–1 Journal of Clinical Investigation ·Guoqiang Jiang, Zhihua Li, Franklin Liu, Kenneth Ellsworth, Qing Dallas-Yang, Margaret Wu, John Ronan, Christine Esau, Cain Murphy, Deborah Szalkowski, Raynald Bergeron, Thomas W. Doebber, Bei B. Zhang	2005	226
11	MK-0767, a novel dual PPARα/γ agonist, displays robust antihyperglycemic and hypolipidemic activities Biochemical and Biophysical Research Communications ·Thomas W. Doebber, Linda Kelly, Gaochao Zhou, Roger Meurer, Chhabi Biswas, Ying Li, Margaret Wu, Marc C. Ippolito, Yu‐Sheng Chao, Pei-Ran Wang, Samuel D. Wright, David E. Moller, Joel P. Berger	2004	26
12	Phenylacetic acid derivatives as hPPAR agonists Bioorganic & Medicinal Chemistry Letters ·Conrad Santini, Gregory D. Berger, Wei Han, Ralph Mosley, Karen L. MacNaul, Joel P. Berger, Thomas W. Doebber, Margaret Wu, David E. Moller, Richard L. Tolman, Soumya P. Sahoo	2003	29
13	Role of AMP-activated protein kinase in mechanism of metformin action Journal of Clinical Investigation ·Gaochao Zhou, Robert P. Myers, Ying Li, Yuli Chen, Xiaolan Shen, Judy Fenyk‐Melody, Margaret Wu, John Ventre, Thomas W. Doebber, Nobuharu Fujii, Nicolas Musi, Michael F. Hirshman, Laurie J. Goodyear, David E. Moller	2001	406
14	Role of AMP-activated protein kinase in mechanism of metformin action Journal of Clinical Investigation ·Gaochao Zhou, Robert P. Myers, Ying Li, Yuli Chen, Xiaolan Shen, Judy Fenyk‐Melody, Margaret Wu, John Ventre, Thomas W. Doebber, Nobuharu Fujii, Nicolas Musi, Michael F. Hirshman, Laurie J. Goodyear, David E. Moller Hit paper breakdown →	2001	4500
15	Evidence for Peroxisome Proliferator-Activated Receptor (PPAR)α-Independent Peroxisome Proliferation: Effects of PPARγ/δ-Specific Agonists in PPARα-Null Mice Molecular Pharmacology ·John G. DeLuca, Thomas W. Doebber, Linda J Kelly, Ramon K. Kemp, Sylvain Molon-Noblot, Soumya P. Sahoo, John Ventre, Margaret Wu, Jeffrey M. Peters, Frank J. Gonzalez, David E. Moller	2000	2
16	Peroxisome Proliferator-Activated Receptors γ and α Mediate in Vivo Regulation of Uncoupling Protein (UCP-1, UCP-2, UCP-3) Gene Expression Endocrinology ·Linda Kelly, Pasquale P. Vicario, G M Thompson, Mari R. Candelore, Thomas W. Doebber, John Ventre, Margaret Wu, Roger Meurer, Michael J. Forrest, Michael W. Conner, Margaret A. Cascieri, David E. Moller	1998	245
17	An antidiabetic thiazolidinedione potentiates insulin stimulation of glycogen synthase in rat adipose tissues. Endocrinology ·N. Berger, Chhabi Biswas, D. Neil Hayes, John Ventre, Margaret Wu, Thomas W. Doebber	1996	24
18	Down-regulation of the Expression of the Obese Gene by an Antidiabetic Thiazolidinedione in Zucker Diabetic Fatty Rats and db/db Mice Journal of Biological Chemistry ·Bei Zhang, Michael P. Graziano, Thomas W. Doebber, Mark D. Leibowitz, Sylvia White-Carrington, Deborah Szalkowski, Patricia J. Hey, Margaret Wu, Catherine A. Cullinan, Philip J. Bailey, Bettina Löllmann, Robert Frederich, Jeffrey S. Flier, Catherine D. Strader, Roy G. Smith	1996	161
19	Dietary orotic acid accentuates the hepatic response to phenobarbital in rats Biochemistry and Cell Biology ·D. S. M. Haines, Margaret Wu, Sonya D. Tokmakjian	1990	1
20	Intestinal Uptake of Macromolecules The Journal of Immunology ·W. Allan Walker, Margaret Wu, Kurt J. Isselbacher, Kurt J. Bloch	1975	41

About Margaret Wu

Margaret Wu is a scholar working on Biochemistry, Physiology, Endocrinology, Diabetes and Metabolism, Molecular Biology and Cancer Research, having authored 56 papers that have together received 8.7k indexed citations. Recurring topics across this work include Peroxisome Proliferator-Activated Receptors (22 papers), Adipose Tissue and Metabolism (16 papers), Metabolism, Diabetes, and Cancer (15 papers), Pancreatic function and diabetes (8 papers), Diabetes Treatment and Management (7 papers), Adipokines, Inflammation, and Metabolic Diseases (7 papers), Cancer, Lipids, and Metabolism (5 papers) and Receptor Mechanisms and Signaling (4 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (1.9k citations), Physiology (2.5k citations), Endocrine and Autonomic Systems (572 citations), Molecular Biology (5.2k citations) and Biochemistry (505 citations). Margaret Wu has collaborated with scholars based in United States, Australia and Tunisia. Frequent co-authors include Thomas W. Doebber, David E. Moller, John Ventre, Gaochao Zhou, Yuli Chen, Judy Fenyk‐Melody, Laurie J. Goodyear, Nobuharu Fujii, Michael F. Hirshman and Xiaolan Shen. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Clinical Investigation, Biochemical and Biophysical Research Communications, Journal of Medicinal Chemistry and Endocrinology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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