Thomas W. Doebber

11.3k citations

58 papers · 9.1k indexed · 1 hit paper · h-index 34

Impact in

Endocrinology, Diabetes and Metabolism top 0.5%
- Diabetes Treatment and Management
- Diet, Metabolism, and Disease
Biochemistry top 0.5%

Papers in

Biochemistry 14
- Eicosanoids and Hypertension Pharmacology 6
Physiology 27
- Adipose Tissue and Metabolism 20

Co-authors: Margaret Wu David E. Moller John Ventre Gaochao Zhou Yuli Chen Nobuharu Fujii Robert P. Myers Judy Fenyk‐Melody
Journals: Bioorganic & Medicinal Chemistry Letters (11 papers)Journal of Medicinal Chemistry (9 papers)Endocrinology (7 papers)Journal of Clinical Investigation (6 papers)Biochemical and Biophysical Research Communications (5 papers)
Partner nations: United States Australia Belgium

In The Last Decade

Thomas W. Doebber

58 papers receiving 8.8k citations

Hit Papers

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Role of AMP-activated protein kinase in mechanism of metformin action 2001 · 4.5k citations

Peers

Countries citing papers authored by Thomas W. Doebber

Since Specialization

Citations

This map shows the geographic impact of Thomas W. Doebber's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas W. Doebber with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas W. Doebber more than expected).

Fields of papers citing papers by Thomas W. Doebber

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas W. Doebber. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas W. Doebber. The network helps show where Thomas W. Doebber may publish in the future.

Co-authors

The 25 scholars most cited alongside Thomas W. Doebber, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Thomas W. Doebber Line = papers co-authored together Thomas W. Doebber links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities Bioorganic & Medicinal Chemistry Letters ·Haifeng Tang, Steven Trac, Zhe Feng, Vinay Durbhakula, Lihu Yang, Dorothy Levorse, Karen Owens, Taro E. Akiyama, Raynald Bergeron, Gino Castriota, Thomas W. Doebber, Kenneth Ellsworth, Michael E. Lassman, Li Cai, Margaret Wu, Bei B. Zhang, Kevin T. Chapman, Sander G. Mills, Joel P. Berger, Alexander Pasternak	2010	13
2	Discovery of a Peroxisome Proliferator Activated Receptor γ (PPARγ) Modulator with Balanced PPARα Activity for the Treatment of Type 2 Diabetes and Dyslipidemia Journal of Medicinal Chemistry ·Weiguo Liu, Kun Liu, Harold B. Wood, Margaret E. McCann, Thomas W. Doebber, Ching H. Chang, Taro E. Akiyama, Monica Einstein, Joel P. Berger, Peter T. Meinke	2009	18
3	Discovery of (2R)-2-(3-{3-[(4-Methoxyphenyl)carbonyl]-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl}phenoxy)butanoic Acid (MK-0533): A Novel Selective Peroxisome Proliferator-Activated Receptor γ Modulator for the Treatment of Type 2 Diabetes Mellitus with a Reduced Potential to Increase Plasma and Extracellular Fluid Volume Journal of Medicinal Chemistry ·John J. Acton, Taro E. Akiyama, Ching H. Chang, Lawrence F. Colwell, Sheryl D. Debenham, Thomas W. Doebber, Monica Einstein, Kun Liu, Margaret E. McCann, David E. Moller, Eric S. Muise, 隆志士谷, John R. Thompson, Kenny K. Wong, Margaret Wu, Libo Xu, Peter T. Meinke, Joel P. Berger, Harold B. Wood	2009	47
4	Highly functionalized 7-azaindoles as selective PPARγ modulators Bioorganic & Medicinal Chemistry Letters ·Sheryl D. Debenham, Audrey Chan, U. Phani Kumari, Weiguo Liu, Harold B. Wood, 斯波廣大, Lawrence F. Colwell, Bahanu Habulihaz, Taro E. Akiyama, Monica Einstein, Thomas W. Doebber, Neelam Sharma, 修一朗田川, Margaret Wu, Joel P. Berger, Peter T. Meinke	2008	15
5	Peroxisome Proliferator-Activated Receptor (PPAR)-α Agonism Prevents the Onset of Type 2 Diabetes in Zucker Diabetic Fatty Rats: A Comparison with PPARγ Agonism Endocrinology ·Raynald Bergeron, Jun Yao, John Woods, Emanuel Zycband, Patricia Ginez Povez, Zhihua Li, Alan Adams, Joel P. Berger, Bei B. Zhang, David E. Moller, Thomas W. Doebber	2006	36
6	Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase–1 Journal of Clinical Investigation ·Guoqiang Jiang, Zhihua Li, Franklin Liu, Kenneth Ellsworth, Qing Dallas-Yang, Margaret Wu, John Ronan, Christine Esau, Cain Murphy, Deborah Szalkowski, Raynald Bergeron, Thomas W. Doebber, Bei B. Zhang	2005	226
7	MK-0767, a novel dual PPARα/γ agonist, displays robust antihyperglycemic and hypolipidemic activities Biochemical and Biophysical Research Communications ·Thomas W. Doebber, Linda Kelly, Gaochao Zhou, Roger Meurer, Chhabi Biswas, Ying Li, Margaret Wu, Marc C. Ippolito, Yu‐Sheng Chao, Pei-Ran Wang, Samuel D. Wright, David E. Moller, Joel P. Berger	2004	26
8	Aryloxazolidinediones: identification of potent orally active PPAR dual α/γ agonists Bioorganic & Medicinal Chemistry Letters ·Ranjit C. Desai, Duma Margaretha, A. Abounadi, Hiroo Koyama, E. Joseph Metzger, Chih-Mou Hsieh, Karen L. MacNaul, Thomas W. Doebber, Joel P. Berger, Kwan Leung, Ronald B. Franklin, David E. Moller, James V. Heck, Soumya P. Sahoo	2003	18
9	5-Aryl thiazolidine-2,4-diones: discovery of PPAR dual α/γ agonists as antidiabetic agents Bioorganic & Medicinal Chemistry Letters ·Ranjit C. Desai, A. Abounadi, E. Joseph Metzger, Jongho Jung, Duma Margaretha, Karen L. MacNaul, Joel P. Berger, Thomas W. Doebber, Kwan Leung, David E. Moller, James V. Heck, Soumya P. Sahoo	2003	42
10	5-Aryl thiazolidine-2,4-diones as selective PPARγ agonists Bioorganic & Medicinal Chemistry Letters ·Hiroo Koyama, Elena Tadeo, A. Abounadi, E. Joseph Metzger, Jongho Jung, Duma Margaretha, Daniel J. Miller, Richard L. Tolman, Karen L. MacNaul, Joel P. Berger, Thomas W. Doebber, Kwan Leung, David E. Moller, James V. Heck, Soumya P. Sahoo	2003	34
11	Amphipathic 3-Phenyl-7-propylbenzisoxazoles; human pPaR γ, δ and α agonists Bioorganic & Medicinal Chemistry Letters ·Alan D. Adams, Sdb Scb, Mary Ann Rousseau, Conrad Santini, A. Brian Jones, Karen L. MacNaul, Joel P. Berger, Thomas W. Doebber, David E. Moller	2003	34
12	Phenylacetic acid derivatives as hPPAR agonists Bioorganic & Medicinal Chemistry Letters ·Conrad Santini, Gregory D. Berger, A. Abounadi, Ralph Mosley, Karen L. MacNaul, Joel P. Berger, Thomas W. Doebber, Margaret Wu, David E. Moller, Richard L. Tolman, Soumya P. Sahoo	2003	29
13	Role of AMP-activated protein kinase in mechanism of metformin action Journal of Clinical Investigation ·Gaochao Zhou, Robert P. Myers, Ying Li, Yuli Chen, Xiaolan Shen, Judy Fenyk‐Melody, Margaret Wu, John Ventre, Thomas W. Doebber, Nobuharu Fujii, Nicolas Musi, Michael F. Hirshman, Laurie J. Goodyear, David E. Moller	2001	406
14	Role of AMP-activated protein kinase in mechanism of metformin action Journal of Clinical Investigation ·Gaochao Zhou, Robert P. Myers, Ying Li, Yuli Chen, Xiaolan Shen, Judy Fenyk‐Melody, Margaret Wu, John Ventre, Thomas W. Doebber, Nobuharu Fujii, Nicolas Musi, Michael F. Hirshman, Laurie J. Goodyear, David E. Moller Hit paper breakdown →	2001	4500
15	Evidence for Peroxisome Proliferator-Activated Receptor (PPAR)α-Independent Peroxisome Proliferation: Effects of PPARγ/δ-Specific Agonists in PPARα-Null Mice Molecular Pharmacology ·John G. DeLuca, Thomas W. Doebber, Linda J Kelly, L. N. Mirzoyan, Sylvain Molon-Noblot, Soumya P. Sahoo, John Ventre, Margaret Wu, Jeffrey M. Peters, Frank J. Gonzalez, David E. Moller	2000	2
16	Evidence for Peroxisome Proliferator-Activated Receptor (PPAR)α-Independent Peroxisome Proliferation: Effects of PPARγ/δ-Specific Agonists in PPARα-Null Mice Molecular Pharmacology ·John G. DeLuca, Thomas W. Doebber, Linda J Kelly, L. N. Mirzoyan, Sylvain Molon-Noblot, Soumya P. Sahoo, John Ventre, Margaret Wu, Jeffrey M. Peters, Frank J. Gonzalez, David E. Moller	2000	46
17	Peroxisome Proliferator-Activated Receptors γ and α Mediate in Vivo Regulation of Uncoupling Protein (UCP-1, UCP-2, UCP-3) Gene Expression Endocrinology ·Linda Kelly, Pasquale P. Vicario, G M Thompson, Mari R. Candelore, Thomas W. Doebber, John Ventre, Margaret Wu, Roger Meurer, Michael J. Forrest, Michael W. Conner, Margaret A. Cascieri, David E. Moller	1998	245
18	Down-regulation of the Expression of the Obese Gene by an Antidiabetic Thiazolidinedione in Zucker Diabetic Fatty Rats and db/db Mice Journal of Biological Chemistry ·Bei Zhang, Michael P. Graziano, Thomas W. Doebber, Mark D. Leibowitz, Punyasamudram Sandhya, Deborah Szalkowski, Patricia J. Hey, Margaret Wu, Catherine A. Cullinan, Philip J. Bailey, Injun Ohk, Robert Frederich, Jeffrey S. Flier, Catherine D. Strader, Roy G. Smith	1996	161
19	(±)- Trans -2-(3-methoxy-5-methylsulfonyl-4-propoxyphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran (L-659,989), a novel, potent PAF receptor antagonist Biochemical and Biophysical Research Communications ·Mitree M. Ponpipom, San-Bao Hwang, Thomas W. Doebber, John J. Acton, Alfred W. Alberts, Tesfaye Biftu, C. F. CARMO, Robert L. Bugianesi, John C. Chabala, M. G. Tatko, Donald W. Graham, My‐Hanh Lam, Margaret Wu	1988	49
20	Platelet activating factor (PAF) involvement in endotoxin-induced hypotension in rats. studies with paf-receptor antagonist kadsurenone Biochemical and Biophysical Research Communications ·Thomas W. Doebber, Margaret Wu, James C. Robbins, Lindita Shehu-Gjikolli, Michael N. Chang, T. Y. Shen	1985	239

About Thomas W. Doebber

Thomas W. Doebber is a scholar working on Biochemistry, Physiology, Molecular Biology, Nutrition and Dietetics and Endocrinology, Diabetes and Metabolism, having authored 58 papers that have together received 9.1k indexed citations. Recurring topics across this work include Peroxisome Proliferator-Activated Receptors (28 papers), Adipose Tissue and Metabolism (20 papers), Metabolism, Diabetes, and Cancer (15 papers), Eicosanoids and Hypertension Pharmacology (6 papers), Glycosylation and Glycoproteins Research (5 papers), Cholesterol and Lipid Metabolism (4 papers), Adipokines, Inflammation, and Metabolic Diseases (4 papers) and Carbohydrate Chemistry and Synthesis (4 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (1.9k citations), Biochemistry (674 citations), Physiology (2.4k citations), Molecular Biology (6.0k citations) and Endocrine and Autonomic Systems (350 citations). Thomas W. Doebber has collaborated with scholars based in United States, Australia and Belgium. Frequent co-authors include Margaret Wu, David E. Moller, John Ventre, Gaochao Zhou, Yuli Chen, Nobuharu Fujii, Robert P. Myers, Judy Fenyk‐Melody, Laurie J. Goodyear and Michael F. Hirshman. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Endocrinology, Journal of Clinical Investigation and Biochemical and Biophysical Research Communications.

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