Louis Leung

1.8k citations

24 papers · 754 indexed · h-index 16

Pharmacology top 1%
- Pharmacogenetics and Drug Metabolism 10
- Drug-Induced Hepatotoxicity and Protection 3
Biological Psychiatry top 10%
Computational Theory and Mathematics top 5%
- Computational Drug Discovery Methods 3
Pharmacology top 10%
- Pharmacogenetics and Drug Metabolism 10
- Drug-Induced Hepatotoxicity and Protection 3
Transplantation top 10%
- Renal Transplantation Outcomes and Treatments 2
Pediatrics, Perinatology and Child Health
- Pharmacological Effects and Toxicity Studies 7
Oncology
- Drug Transport and Resistance Mechanisms 6
Molecular Biology
- Metabolomics and Mass Spectrometry Studies 2
Physiology
- Alzheimer's disease research and treatments 2

Co-authors: Thomas A. Baillie R. Scott Obach Amit S. Kalgutkar John Y. Kao Hugh A. Barton Yvonne Will Michael D. Aleo Falgun Shah
Cited by: Pharmacology Biological Psychiatry Computational Theory and Mathematics
Journals: Journal of Agricultural and Food Chemistry (1 paper)Journal of Medicinal Chemistry (2 papers)Journal of Pharmacology and Experimental Therapeutics (2 papers)
Partner nations: United States Canada Mexico

In The Last Decade

Louis Leung

23 papers receiving 717 citations

Peers

Countries citing papers authored by Louis Leung

Since Specialization

Citations

This map shows the geographic impact of Louis Leung's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Louis Leung with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Louis Leung more than expected).

Fields of papers citing papers by Louis Leung

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Louis Leung. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Louis Leung. The network helps show where Louis Leung may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Louis Leung, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Louis Leung Line = papers co-authored together Louis Leung links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Desvenlafaxine and Venlafaxine Exert Minimal In Vitro Inhibition of Human Cytochrome P450 and P-Glycoprotein Activities Psychopharmacology Bulletin ·Aram Oganesian,Adam D. Shilling,Ruth Young-Sciame,Judy Tran,Adiba Watanyar,Farooq Azam,John Y. Kao,Louis Leung	2025	0
2	Clearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance Mechanisms Drug Metabolism and Disposition ·Louis Leung,Xin Yang,Timothy J. Strelevitz,Justin I. Montgomery,Matthew F. Brown,Michael Zientek,Christopher Banfield,A. Gilbert,Atli Thorarensen,Martin E. Dowty	2016	25
3	Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanisticin vitroAssays Toxicological Sciences ·Falgun Shah,Louis Leung,Hugh A. Barton,Yvonne Will,A. David Rodrigues,Nigel Greene,Michael D. Aleo	2015	106
4	Disposition and Metabolic Profiling of [14C]Cerlapirdine Using Accelerator Mass Spectrometry Drug Metabolism and Disposition ·Susanna Tse,Louis Leung,Sangeeta Raje,Mark Seymour,Yoko Shishikura,R. Scott Obach	2014	14
5	Drug Metabolites as Cytochrome P450 Inhibitors: A Retrospective Analysis and Proposed Algorithm for Evaluation of the Pharmacokinetic Interaction Potential of Metabolites in Drug Discovery and Development Drug Metabolism and Disposition ·Ernesto Callegari,Amit S. Kalgutkar,Louis Leung,R. Scott Obach,David R. Plowchalk,Susanna Tse	2013	25
6	Cerebrospinal Fluid β-Amyloid Turnover in the Mouse, Dog, Monkey and Human Evaluated by Systematic Quantitative Analyses Neurodegenerative Diseases ·Yasong Lu,Hugh A. Barton,Louis Leung,Liming Zhang,Éva Hajós‐Korcsok,Charles E. Nolan,Jianhua Liu,Stacey L. Becker,Kathleen M. Wood,Ashley Robshaw,Christine K. Taylor,Brian T. O’Neill,Michael A. Brodney,David Riddell	2012	18
7	Cerebrospinal Fluid Amyloid-β (Aβ) as an Effect Biomarker for Brain Aβ Lowering Verified by Quantitative Preclinical Analyses Journal of Pharmacology and Experimental Therapeutics ·Yasong Lu,David Riddell,Éva Hajós‐Korcsok,Kelly R. Bales,Kathleen M. Wood,Charles E. Nolan,Ashley Robshaw,Liming Zhang,Louis Leung,Stacey L. Becker,Elaine Tseng,Jason Barricklow,Emily Happy Miller,Sarah M. Osgood,Brian T. O’Neill,Michael A. Brodney,Douglas S. Johnson,Martin Pettersson	2012	24
8	Comparative Pharmacokinetics and Metabolism Studies in Lean and Diet- Induced Obese Mice: An Animal Efficacy Model for 11β -Hydroxysteroid Dehydrogenase Type 1 (11β -HSD1) Inhibitors Drug Metabolism Letters ·Mengmeng Wang,Xianbin Tian,Louis Leung,Jianyao Wang,Nicole Houvig,Jason Xiang,Eddine Saiah,Seung Hahm,Vipin Suri,Xin Xu	2011	6
9	Metabolic activation in drug-induced liver injury Drug Metabolism Reviews ·Louis Leung,Amit S. Kalgutkar,R. Scott Obach	2011	88
10	Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCθ inhibitors Bioorganic & Medicinal Chemistry Letters ·Diane H. Boschelli,Joan Subrath,Chuansheng Niu,Biqi Wu,Yan Wang,Julie Lee,Agnes Brennan,Melisa W.Y. Ho,Bijia Deng,Xiaoke Yang,Xin Xu,Louis Leung,Jianyao Wang,James Atherton,Divya Chaudhary	2010	14
11	Using a homology model of cytochrome P450 2D6 to predict substrate site of metabolism Journal of Computer-Aided Molecular Design ·Rayomand J. Unwalla,Jason B. Cross,Sumeet Salaniwal,Adam D. Shilling,Louis Leung,John Y. Kao,Christine Humblet	2010	32
12	C-5 substituted heteroaryl-3-pyridinecarbonitriles as PKCθ inhibitors: Part II Bioorganic & Medicinal Chemistry Letters ·Amar S. Prashad,Daniel Wang,Joan Subrath,Biqi Wu,Melissa Lin,Meiyi Zhang,Natasha Kagan,Julie Lee,Xiaoke Yang,Agnes Brennan,Divya Chaudhary,Xin Xu,Louis Leung,Jack Wang,Diane H. Boschelli	2009	16
13	Pharmacokinetics and Metabolic Disposition of Sirolimus in Healthy Male Volunteers After a Single Oral Dose Therapeutic Drug Monitoring ·Louis Leung,Heng‐Keang Lim,Madelyn Abell,James J. Zimmerman	2006	19
14	Use of canalicular membrane vesicles (CMVs) from rats, dogs, monkeys and humans to assess drug transport across the canalicular membrane Journal of Pharmacological and Toxicological Methods ·Adam D. Shilling,Fardous Mohammad Safiul Azam,John Y. Kao,Louis Leung	2005	26
15	New Insights into Drug Absorption Therapeutic Drug Monitoring ·Mary F. Paine,Louis Leung,Paul B. Watkins	2004	21
16	Identification of a Novel Route of Extraction of Sirolimus in Human Small Intestine: Roles of Metabolism and Secretion Journal of Pharmacology and Experimental Therapeutics ·Mary F. Paine,Louis Leung,Heng‐Keang Lim,Kecheng Liao,Aram Oganesian,Mei-Yi Zhang,Kenneth E. Thummel,Paul B. Watkins	2002	31
17	C-Formylation in the presence of rat brain mitochondria of the 2,3,4,5-tetrahydropyridinium metabolite derived from the psychotomimetic drug phencyclidine Chemical Research in Toxicology ·Zhiyang Zhao,Louis Leung,Anthony J. Trevor,Neal Castagnoli	1991	6
18	Studies on the biotransformation of ketamine. II—quantitative significance of theN-demethylation pathway in ratsin vivo determined by a novel stable isotope technique Journal of Mass Spectrometry ·Louis Leung,Thomas A. Baillie	1989	11
19	Pharmacokinetic and deuterium isotope effect studies on the metabolism of formaldehyde and formate to carbon dioxide in rats in vivo. Drug Metabolism and Disposition ·Larry K. Keefer,Anthony J. Streeter,Louis Leung,W. C. Perry,Hongzhen Hu,Thomas A. Baillie	1987	10
20	Comparative pharmacology in the rat of ketamine and its two principal metabolites, norketamine and (Z)-6-hydroxynorketamine Journal of Medicinal Chemistry ·Louis Leung,Thomas A. Baillie	1986	105

About Louis Leung

Louis Leung is a scholar working on Pharmacology, Biological Psychiatry and Transplantation, having authored 24 papers that have together received 754 indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (10 papers), Pharmacological Effects and Toxicity Studies (7 papers), Drug Transport and Resistance Mechanisms (6 papers), Computational Drug Discovery Methods (3 papers), Drug-Induced Hepatotoxicity and Protection (3 papers), Metabolomics and Mass Spectrometry Studies (2 papers), Renal Transplantation Outcomes and Treatments (2 papers) and Alzheimer's disease research and treatments (2 papers). The work is most often cited by research in Pharmacology (287 citations), Biological Psychiatry (40 citations) and Computational Theory and Mathematics (117 citations). Louis Leung has collaborated with scholars based in United States, Canada and Mexico. Frequent co-authors include Thomas A. Baillie, R. Scott Obach, Amit S. Kalgutkar, John Y. Kao, Hugh A. Barton, Yvonne Will, Michael D. Aleo, Falgun Shah, Lilian Yengi and Nigel Greene. Their work appears in journals such as Journal of Agricultural and Food Chemistry, Journal of Medicinal Chemistry and Journal of Pharmacology and Experimental Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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