Louis Leung

1.8k citations

24 papers · 754 indexed · h-index 16

Pharmacology top 1%
Molecular Biology
Oncology
Pharmacology top 10%
Computational Theory and Mathematics top 5%

Co-authors: Thomas A. Baillie R. Scott Obach Amit S. Kalgutkar John Y. Kao Hugh A. Barton Yvonne Will Michael D. Aleo Falgun Shah
Topics: Pharmacogenetics and Drug Metabolism (10 papers)Pharmacological Effects and Toxicity Studies (7 papers)Drug Transport and Resistance Mechanisms (6 papers)
Cited by: Pharmacology Biological Psychiatry Computational Theory and Mathematics
Journals: Journal of Agricultural and Food Chemistry Journal of Medicinal Chemistry Journal of Pharmacology and Experimental Therapeutics
Partner nations: United States Canada Mexico

In The Last Decade

Louis Leung

23 papers receiving 717 citations

Peers

Countries citing papers authored by Louis Leung

Since Specialization

Citations

This map shows the geographic impact of Louis Leung's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Louis Leung with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Louis Leung more than expected).

Fields of papers citing papers by Louis Leung

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Louis Leung. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Louis Leung. The network helps show where Louis Leung may publish in the future.

Co-authorship network of co-authors of Louis Leung

This figure shows the co-authorship network connecting the top 25 collaborators of Louis Leung. A scholar is included among the top collaborators of Louis Leung based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Louis Leung. Louis Leung is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Desvenlafaxine and Venlafaxine Exert Minimal In Vitro Inhibition of Human Cytochrome P450 and P-Glycoprotein Activities 2025 ·Psychopharmacology Bulletin ·Aram Oganesian,Adam D. Shilling,(unknown),(unknown),(unknown),(unknown),John Y. Kao,Louis Leung	0
2	Clearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance Mechanisms 2016 ·Drug Metabolism and Disposition ·Louis Leung,Xin Yang,Timothy J. Strelevitz,Justin I. Montgomery,Matthew F. Brown,Michael Zientek,Christopher Banfield,A. Gilbert,Atli Thorarensen,Martin E. Dowty	25
3	Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanisticin vitroAssays 2015 ·Toxicological Sciences ·Falgun Shah,Louis Leung,Hugh A. Barton,Yvonne Will,A. David Rodrigues,Nigel Greene,Michael D. Aleo	106
4	Disposition and Metabolic Profiling of [14C]Cerlapirdine Using Accelerator Mass Spectrometry 2014 ·Drug Metabolism and Disposition ·Susanna Tse,Louis Leung,Sangeeta Raje,Mark Seymour,Yoko Shishikura,R. Scott Obach	14
5	Drug Metabolites as Cytochrome P450 Inhibitors: A Retrospective Analysis and Proposed Algorithm for Evaluation of the Pharmacokinetic Interaction Potential of Metabolites in Drug Discovery and Development 2013 ·Drug Metabolism and Disposition ·Ernesto Callegari,Amit S. Kalgutkar,Louis Leung,R. Scott Obach,David R. Plowchalk,Susanna Tse	25
6	Cerebrospinal Fluid β-Amyloid Turnover in the Mouse, Dog, Monkey and Human Evaluated by Systematic Quantitative Analyses 2012 ·Neurodegenerative Diseases ·Yasong Lu,Hugh A. Barton,Louis Leung,Liming Zhang,Éva Hajós‐Korcsok,Charles E. Nolan,Jianhua Liu,Stacey L. Becker,Kathleen M. Wood,Ashley Robshaw,(unknown),Brian T. O’Neill,Michael A. Brodney,David Riddell	18
7	Cerebrospinal Fluid Amyloid-β (Aβ) as an Effect Biomarker for Brain Aβ Lowering Verified by Quantitative Preclinical Analyses 2012 ·Journal of Pharmacology and Experimental Therapeutics ·Yasong Lu,David Riddell,Éva Hajós‐Korcsok,Kelly R. Bales,Kathleen M. Wood,Charles E. Nolan,Ashley Robshaw,Liming Zhang,Louis Leung,Stacey L. Becker,Elaine Tseng,(unknown),Emily Happy Miller,Sarah M. Osgood,Brian T. O’Neill,Michael A. Brodney,Douglas S. Johnson,Martin Pettersson	24
8	Comparative Pharmacokinetics and Metabolism Studies in Lean and Diet- Induced Obese Mice: An Animal Efficacy Model for 11β -Hydroxysteroid Dehydrogenase Type 1 (11β -HSD1) Inhibitors 2011 ·Drug Metabolism Letters ·Mengmeng Wang,Xianbin Tian,Louis Leung,Jianyao Wang,(unknown),Jason Xiang,Eddine Saiah,Seung Hahm,Vipin Suri,Xin Xu	6
9	Metabolic activation in drug-induced liver injury 2011 ·Drug Metabolism Reviews ·Louis Leung,Amit S. Kalgutkar,R. Scott Obach	88
10	Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCθ inhibitors 2010 ·Bioorganic & Medicinal Chemistry Letters ·Diane H. Boschelli,Joan Subrath,(unknown),Biqi Wu,Yan Wang,Julie Lee,Agnes Brennan,(unknown),Bijia Deng,Xiaoke Yang,Xin Xu,Louis Leung,Jianyao Wang,James Atherton,Divya Chaudhary	14
11	Using a homology model of cytochrome P450 2D6 to predict substrate site of metabolism 2010 ·Journal of Computer-Aided Molecular Design ·Rayomand J. Unwalla,Jason B. Cross,Sumeet Salaniwal,Adam D. Shilling,Louis Leung,John Y. Kao,Christine Humblet	32
12	C-5 substituted heteroaryl-3-pyridinecarbonitriles as PKCθ inhibitors: Part II 2009 ·Bioorganic & Medicinal Chemistry Letters ·Amar S. Prashad,Daniel Wang,Joan Subrath,Biqi Wu,Melissa Lin,Meiyi Zhang,(unknown),Julie Lee,Xiaoke Yang,Agnes Brennan,Divya Chaudhary,Xin Xu,Louis Leung,Jack Wang,Diane H. Boschelli	16
13	Pharmacokinetics and Metabolic Disposition of Sirolimus in Healthy Male Volunteers After a Single Oral Dose 2006 ·Therapeutic Drug Monitoring ·Louis Leung,Heng‐Keang Lim,(unknown),James J. Zimmerman	19
14	Use of canalicular membrane vesicles (CMVs) from rats, dogs, monkeys and humans to assess drug transport across the canalicular membrane 2005 ·Journal of Pharmacological and Toxicological Methods ·Adam D. Shilling,Fardous Mohammad Safiul Azam,John Y. Kao,Louis Leung	26
15	New Insights into Drug Absorption 2004 ·Therapeutic Drug Monitoring ·Mary F. Paine,Louis Leung,Paul B. Watkins	21
16	Identification of a Novel Route of Extraction of Sirolimus in Human Small Intestine: Roles of Metabolism and Secretion 2002 ·Journal of Pharmacology and Experimental Therapeutics ·Mary F. Paine,Louis Leung,Heng‐Keang Lim,(unknown),Aram Oganesian,(unknown),Kenneth E. Thummel,Paul B. Watkins	31
17	C-Formylation in the presence of rat brain mitochondria of the 2,3,4,5-tetrahydropyridinium metabolite derived from the psychotomimetic drug phencyclidine 1991 ·Chemical Research in Toxicology ·Zhiyang Zhao,Louis Leung,Anthony J. Trevor,Neal Castagnoli	6
18	Studies on the biotransformation of ketamine. II—quantitative significance of theN-demethylation pathway in ratsin vivo determined by a novel stable isotope technique 1989 ·Journal of Mass Spectrometry ·Louis Leung,Thomas A. Baillie	11
19	Pharmacokinetic and deuterium isotope effect studies on the metabolism of formaldehyde and formate to carbon dioxide in rats in vivo. 1987 ·Drug Metabolism and Disposition ·Larry K. Keefer,Anthony J. Streeter,Louis Leung,(unknown),Hongzhen Hu,Thomas A. Baillie	10
20	Comparative pharmacology in the rat of ketamine and its two principal metabolites, norketamine and (Z)-6-hydroxynorketamine 1986 ·Journal of Medicinal Chemistry ·Louis Leung,Thomas A. Baillie	105

About Louis Leung

Louis Leung is a scholar working on Pharmacology, Biological Psychiatry and Transplantation, having authored 24 papers that have together received 754 indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (10 papers), Pharmacological Effects and Toxicity Studies (7 papers) and Drug Transport and Resistance Mechanisms (6 papers). The work is most often cited by research in Pharmacology (287 citations), Biological Psychiatry (40 citations) and Computational Theory and Mathematics (117 citations). Louis Leung has collaborated with scholars based in United States, Canada and Mexico. Frequent co-authors include Thomas A. Baillie, R. Scott Obach, Amit S. Kalgutkar, John Y. Kao, Hugh A. Barton, Yvonne Will, Michael D. Aleo, Falgun Shah, Lilian Yengi and Nigel Greene. Their work appears in journals such as Journal of Agricultural and Food Chemistry, Journal of Medicinal Chemistry and Journal of Pharmacology and Experimental Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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