Heng‐Keang Lim

2.2k total citations
33 papers, 1.2k citations indexed

About

Heng‐Keang Lim is a scholar working on Molecular Biology, Pharmacology and Spectroscopy. According to data from OpenAlex, Heng‐Keang Lim has authored 33 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 12 papers in Pharmacology and 11 papers in Spectroscopy. Recurrent topics in Heng‐Keang Lim's work include Pharmacogenetics and Drug Metabolism (12 papers), Analytical Chemistry and Chromatography (9 papers) and Mass Spectrometry Techniques and Applications (7 papers). Heng‐Keang Lim is often cited by papers focused on Pharmacogenetics and Drug Metabolism (12 papers), Analytical Chemistry and Chromatography (9 papers) and Mass Spectrometry Techniques and Applications (7 papers). Heng‐Keang Lim collaborates with scholars based in United States, Canada and Belgium. Heng‐Keang Lim's co-authors include S. Ball, Georgia Cornelius, Elizabeth A. Dierks, Hong‐Xing Zhang, Kevin Cook, Carlo Sensenhauser, Samuel F. Sisenwine, Yin Liang Hsieh, Jack D. Henion and Bruce Ganem and has published in prestigious journals such as Analytical Chemistry, Journal of Pharmacology and Experimental Therapeutics and Journal of Chromatography A.

In The Last Decade

Heng‐Keang Lim

29 papers receiving 1.1k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Heng‐Keang Lim United States	19	562	436	332	270	132	33	1.2k
JoAnn Scatina United States	22	681 1.2×	483 1.1×	210 0.6×	318 1.2×	90 0.7×	56	1.6k
James G. Baxter United States	8	552 1.0×	441 1.0×	173 0.5×	385 1.4×	201 1.5×	10	1.3k
James A. Eckstein United States	17	560 1.0×	618 1.4×	151 0.5×	321 1.2×	65 0.5×	25	1.8k
Deborah J. Newton United States	15	903 1.6×	419 1.0×	105 0.3×	593 2.2×	104 0.8×	18	1.5k
Chungang Gu United States	16	403 0.7×	721 1.7×	355 1.1×	154 0.6×	56 0.4×	46	1.6k
Donald Tweedie United States	24	834 1.5×	499 1.1×	103 0.3×	568 2.1×	158 1.2×	49	1.6k
Tian J. Yang United States	15	721 1.3×	314 0.7×	88 0.3×	365 1.4×	139 1.1×	28	1.2k
David J. Rance United Kingdom	15	834 1.5×	636 1.5×	178 0.5×	452 1.7×	216 1.6×	18	1.7k
Shigeyuki Terashita Japan	16	666 1.2×	302 0.7×	136 0.4×	705 2.6×	132 1.0×	30	1.3k
G. Gordon Gibson United Kingdom	18	710 1.3×	489 1.1×	77 0.2×	370 1.4×	75 0.6×	38	1.4k

Countries citing papers authored by Heng‐Keang Lim

Since Specialization

Citations

This map shows the geographic impact of Heng‐Keang Lim's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Heng‐Keang Lim with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Heng‐Keang Lim more than expected).

Fields of papers citing papers by Heng‐Keang Lim

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Heng‐Keang Lim. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Heng‐Keang Lim. The network helps show where Heng‐Keang Lim may publish in the future.

Co-authorship network of co-authors of Heng‐Keang Lim

This figure shows the co-authorship network connecting the top 25 collaborators of Heng‐Keang Lim. A scholar is included among the top collaborators of Heng‐Keang Lim based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Heng‐Keang Lim. Heng‐Keang Lim is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Flinders, Bryn, Bhanu Singh, Heng‐Keang Lim, et al.. (2025). Investigation into Drug-Induced Liver Damage Using Multimodal Mass Spectrometry Imaging. Journal of the American Society for Mass Spectrometry. 36(2). 265–276.

Lim, Heng‐Keang, Jie Chen, Wing Lam, et al.. (2023). Metabolism and disposition of JNJ-10450232 (NTM-006) in rats, dogs, monkeys and humans. Regulatory Toxicology and Pharmacology. 161. 105379–105379. 5 indexed citations

Gong, Yong, Jie Chen, Heng‐Keang Lim, Naidong Weng, & Rhys Salter. (2021). Bifunctionalized isotopologs as calibrants for standard‐free quantitation of drug metabolites in plasma by liquid chromatography coupled with radiometry and mass spectrometry. Biomedical Chromatography. 36(1). e5242–e5242.

Otieno, Monicah A., Jan Snoeys, Wing Lam, et al.. (2017). Fasiglifam (TAK-875): Mechanistic Investigation and Retrospective Identification of Hazards for Drug Induced Liver Injury. Toxicological Sciences. 163(2). 374–384. 66 indexed citations

Yu, Hongbin, Suresh K. Balani, Wei‐Chao Chen, et al.. (2015). Contribution of Metabolites to P450 Inhibition–Based Drug–Drug Interactions: Scholarship from the Drug Metabolism Leadership Group of the Innovation and Quality Consortium Metabolite Group. Drug Metabolism and Disposition. 43(4). 620–630. 24 indexed citations

Lim, Heng‐Keang, Yuan Cao, Xi Qiu, José de Paula Silva, & David C. Evans. (2014). A Nonradioactive Approach to Investigate the Metabolism of Therapeutic Peptides by Tagging with 127I and Using Inductively-Coupled Plasma Mass Spectrometry Analysis. Drug Metabolism and Disposition. 43(1). 17–26.

Xu, Yaodong, Yang Yuan, Naidong Weng, et al.. (2013). LC–ESI-MS/MS quantification of 4β-hydroxycholesterol and cholesterol in plasma samples of limited volume. Journal of Pharmaceutical and Biomedical Analysis. 85. 145–154. 27 indexed citations

Li, Pei, Yong Gong, Heng‐Keang Lim, et al.. (2013). Bio-generation of stable isotope labeled internal standards for absolute and relative quantitation of drug metabolites in plasma samples by LC–MS/MS. Journal of Chromatography B. 926. 92–100. 12 indexed citations

Lim, Heng‐Keang, Wing Lam, Jie Chen, et al.. (2012). Free radical metabolism of raloxifene in human liver microsomes. Xenobiotica. 42(8). 737–747. 6 indexed citations

10.

Grimm, Scott, Heidi J. Einolf, Kan He, et al.. (2009). The Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of America. Drug Metabolism and Disposition. 37(7). 1355–1370. 224 indexed citations

11.

Lim, Heng‐Keang, Jie Chen, Kevin Cook, et al.. (2008). A generic method to detect electrophilic intermediates using isotopic pattern triggered data‐dependent high‐resolution accurate mass spectrometry. Rapid Communications in Mass Spectrometry. 22(8). 1295–1311. 57 indexed citations

12.

Lim, Heng‐Keang, Jie Chen, Carlo Sensenhauser, Kevin Cook, & Vangala Subrahmanyam. (2007). Metabolite identification by data‐dependent accurate mass spectrometric analysis at resolving power of 60 000 in external calibration mode using an LTQ/Orbitrap. Rapid Communications in Mass Spectrometry. 21(12). 1821–1832. 78 indexed citations

13.

Leung, Louis, et al.. (2006). Pharmacokinetics and Metabolic Disposition of Sirolimus in Healthy Male Volunteers After a Single Oral Dose. Therapeutic Drug Monitoring. 28(1). 51–61. 19 indexed citations

14.

Lim, Heng‐Keang, et al.. (2005). AUTOMATED SCREENING WITH CONFIRMATION OF MECHANISM-BASED INACTIVATION OF CYP3A4, CYP2C9, CYP2C19, CYP2D6, AND CYP1A2 IN POOLED HUMAN LIVER MICROSOMES. Drug Metabolism and Disposition. 33(8). 1211–1219. 62 indexed citations

15.

Zimmerman, James J., Kenneth C. Lasseter, Heng‐Keang Lim, et al.. (2005). Pharmacokinetics of Sirolimus (Rapamycin) in Subjects With Mild to Moderate Hepatic Impairment. The Journal of Clinical Pharmacology. 45(12). 1368–1372. 24 indexed citations

16.

Gu, M. F. & Heng‐Keang Lim. (2001). An intelligent data acquisition system for simultaneous screening of microsomal stability and metabolite profiling by liquid chromatography/mass spectrometry. Journal of Mass Spectrometry. 36(9). 1053–1061. 5 indexed citations

17.

Dierks, Elizabeth A., et al.. (2001). A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry.. PubMed. 29(1). 23–9. 204 indexed citations

18.

Zimmerman, James J., Géraldine M. Ferron, Heng‐Keang Lim, & Vernon D. Parker. (1999). The Effect of a High‐Fat Meal on the Oral Bioavailability of the Immunosuppressant Sirolimus (Rapamycin). The Journal of Clinical Pharmacology. 39(11). 1155–1161. 50 indexed citations

19.

Lim, Heng‐Keang, et al.. (1999). Rapid drug metabolite profiling using fast liquid chromatography, automated multiple-stage mass spectrometry and receptor-binding. Journal of Chromatography A. 831(2). 227–241. 49 indexed citations

20.

Lim, Heng‐Keang, et al.. (1997). High Performance Liquid Chromatographic Isolation and Spectroscopic Characterization of Metabolites from the Bile of Rats Receiving Rapamycin (Sirolimus) Intravenously. Journal of Liquid Chromatography & Related Technologies. 20(11). 1689–1701. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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