Michael D. Aleo

2.7k citations

51 papers · 2.0k indexed · 1 hit paper · h-index 24

Impact in

Pharmacology top 0.2%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
Hepatology top 5%
- Liver physiology and pathology

Papers in

Pharmacology 25
- Drug-Induced Hepatotoxicity and Protection 20
- Pharmacogenetics and Drug Metabolism 18
Nephrology 5
- Chronic Kidney Disease and Diabetes 4

Co-authors: Yvonne Will David A. Price Jonathan Bauman Daniel P. Walker Thomas A. Baillie Amit S. Kalgutkar Antonia F. Stepan Rick G. Schnellmann
Journals: Chemical Research in Toxicology (8 papers)Toxicology and Applied Pharmacology (6 papers)Journal of Pharmacology and Experimental Therapeutics (3 papers)American Journal of Physiology-Renal Physiology (3 papers)Investigative Ophthalmology & Visual Science (2 papers)
Partner nations: United States United Kingdom Belgium

In The Last Decade

Michael D. Aleo

51 papers receiving 2.0k citations

Hit Papers

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Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States 2011 · 494 citations

Peers

Countries citing papers authored by Michael D. Aleo

Since Specialization

Citations

This map shows the geographic impact of Michael D. Aleo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael D. Aleo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael D. Aleo more than expected).

Fields of papers citing papers by Michael D. Aleo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael D. Aleo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael D. Aleo. The network helps show where Michael D. Aleo may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Michael D. Aleo, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael D. Aleo Line = papers co-authored together Michael D. Aleo links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	AI/ML Models to Predict the Severity of Drug-Induced Liver Injury for Small Molecules Chemical Research in Toxicology ·Mohan Rao, Vahid Nassiri, Cristóbal Alhambra, Jan Snoeys, Freddy Van Goethem, Onyi Irrechukwu, Michael D. Aleo, Helena Geys, Kaushik Mitra, Yvonne Will	2023	18
2	An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury Archives of Toxicology ·Shingo Oda, Yuka Uchida, Michael D. Aleo, Petra Koza‐Taylor, Yusuke Matsui, 泰樹黒田, Lisa D. Marroquin, Jessica Whritenour, 厉运超, Tsuyoshi Yokoi	2020	19
3	High-Content Imaging in Human and Rat Hepatocytes Using the Fluorescent Dyes CLF and CMFDA Is Not Specific Enough to Assess BSEP/Bsep and/or MRP2/Mrp2 Inhibition by Cholestatic Drugs Luping Qiu, James E. Finley, Mohammed Taimi, Michael D. Aleo, Christopher Strock, Jonathan B. Gilbert, D. Gerll, Yvonne Will	2015	6
4	Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanisticin vitroAssays Toxicological Sciences ·Falgun Shah, Louis Leung, Hugh A. Barton, Yvonne Will, A. David Rodrigues, Nigel Greene, Michael D. Aleo	2015	106
5	Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes Toxicology and Applied Pharmacology ·Sashi Nadanaciva, Michael D. Aleo, Christopher J. Strock, Donald B. Stedman, Huijun Wang, Yvonne Will	2013	38
6	Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans Toxicological Sciences ·Salman R. Khetani, Chitra Kanchagar, Okechukwu Ukairo, Alain Gloor, Amanda Moore, Lara Mendes de Oliveira Castro, Ki-Dong Kang, Michael D. Aleo, Yvonne Will	2012	169
7	Comparisons betweenin vitrowhole cell imaging andin vivozebrafish-based approaches for identifying potential human hepatotoxicants earlier in pharmaceutical development Drug Metabolism Reviews ·Adrian Hill, Natalie Mesens, Margino Steemans, Jinghai J. Xu, Michael D. Aleo	2012	88
8	Using an in vitro cytotoxicity assay to aid in compound selection for in vivo safety studies Bioorganic & Medicinal Chemistry Letters ·Nigel Greene, Michael D. Aleo, Shirley Louise‐May, David A. Price, Yvonne Will	2010	53
9	A current practice for predicting ocular toxicity of systemically delivered drugs Cutaneous and Ocular Toxicology ·Devrim Ertürk, Nigel Greene, James A. Render, Michael D. Aleo, Frédéric Martin-Achard, James A. Dykens, Fedchenko Zhanna Terentevna	2009	12
10	Ciglitazone-Induced Lenticular Opacities in Rats: In Vivo and Whole Lens Explant Culture Evaluation Journal of Pharmacology and Experimental Therapeutics ·Michael D. Aleo, V.N. Taborov, Nina G. Lavrentieva	2005	15
11	Comparisons between U18666A, Naphthalene, and Galactose on Lens Cholesterol Biosynthesis and Evaluation of Cataract Progression by Scheimpflug and Slit Lamp Exams Investigative Ophthalmology & Visual Science ·Josep Pallarés Personat, Paulo Pequeno, Kamal Elfallah, I De La Fuente Graciani, Michael D. Aleo, Roger Stewart Euler	2003	1
12	Mechanism and Implications of Brown Adipose Tissue Proliferation in Rats and Monkeys Treated with the Thiazolidinedione Darglitazone, a Potent Peroxisome Proliferator-Activated Receptor-γ Agonist Journal of Pharmacology and Experimental Therapeutics ·Michael D. Aleo, Journal Of Saussurea, Gerald P. Nicholls, 一良森本, Gerald L. Coleman, D. Shangeetha, William M. Kluwe	2003	30
13	Endoplasmic reticulum Ca2+ signaling and calpains mediate renal cell death Cell Death and Differentiation ·H. Treutler, Jacopo Bello, Michael D. Aleo, Khaled Machaca, Rick G. Schnellmann	2002	41
14	Mechanistic Analysis ofS-(1,2-Dichlorovinyl)-l-cysteine-Induced Cataractogenesisin Vitro Toxicology and Applied Pharmacology ·Marlyn Andréa de Castro Campos, Michael D. Aleo	1997	10
15	The role of short chain fatty acid substrates in aerobic and glycolytic metabolism in primary cultures of renal proximal tubule cells In Vitro Cellular & Developmental Biology - Animal ·Richard D. Griner, Michael D. Aleo, Rick G. Schnellmann	1993	10
16	The neurotoxicants strychnine and bicuculline protect renal proximal tubules from mitochondrial inhibitor-induced cell death Life Sciences ·Michael D. Aleo, Rick G. Schnellmann	1992	19
17	Primary cultures of rabbit renal proximal tubule cells Toxicology and Applied Pharmacology ·Michael D. Aleo, Mary Taub, Paul J. Kostyniak	1992	28
18	Toxicity of N-(3,5-dichlorophenyl)succinimide and metabolites to rat renal proximal tubules and mitochondria Chemico-Biological Interactions ·Michael D. Aleo, Gary O. Rankin, Kewei Ren, Rick G. Schnellmann	1991	26
19	Primary cultures of rabbit renal proximal tubule cells: II. Selected phase I and phase II metabolic capacities Toxicology in Vitro ·Michael D. Aleo, Mary Taub, James R. Olson, Paul J. Kostyniak	1990	11
20	High Performance Liquid Chromatographic Analysis of Cholesterol in Milk Journal of Dairy Science ·W. Jeffrey Hurst, Michael D. Aleo, Robert A. Martin	1983	18

About Michael D. Aleo

Michael D. Aleo is a scholar working on Pharmacology, Nephrology, Computational Theory and Mathematics, Biochemistry and Pediatrics, Perinatology and Child Health, having authored 51 papers that have together received 2.0k indexed citations. Recurring topics across this work include Drug-Induced Hepatotoxicity and Protection (20 papers), Pharmacogenetics and Drug Metabolism (18 papers), Computational Drug Discovery Methods (10 papers), Drug Transport and Resistance Mechanisms (9 papers), Pharmacological Effects and Toxicity Studies (9 papers), Connexins and lens biology (7 papers), Ion Transport and Channel Regulation (4 papers) and Chronic Kidney Disease and Diabetes (4 papers). The work is most often cited by research in Pharmacology (769 citations), Hepatology (206 citations), Computational Theory and Mathematics (343 citations), Biochemistry (82 citations) and Oncology (309 citations). Michael D. Aleo has collaborated with scholars based in United States, United Kingdom and Belgium. Frequent co-authors include Yvonne Will, David A. Price, Jonathan Bauman, Daniel P. Walker, Thomas A. Baillie, Amit S. Kalgutkar, Antonia F. Stepan, Rick G. Schnellmann, Paul D. Bonin and Rachel Swiss. Their work appears in journals such as Chemical Research in Toxicology, Toxicology and Applied Pharmacology, Journal of Pharmacology and Experimental Therapeutics, American Journal of Physiology-Renal Physiology and Investigative Ophthalmology & Visual Science.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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